List of works - Christophe Furman

4-Oxo-1,4-dihydropyridines as selective CB₂ cannabinoid receptor ligands. Part 2: discovery of new agonists endowed with protective effect against experimental colitis.

scientific article published on 12 October 2012

6-Sulfonylbenzothiazolones as potential scaffolds for the design of 5-HT6 ligands

scientific article

A High Concentration of Melatonin Inhibits In Vitro LDL Peroxidation But Not Oxidized LDL Toxicity Toward Cultured Endothelial Cells

article

Antagonists of the P2X7 receptor: mechanism of enantioselective recognition using highly sulfated and sulfobutylether cyclodextrins by capillary electrokinetic chromatography

scientific article published on 18 July 2014

Antagonists of the adenosine A2A receptor based on a 2-arylbenzoxazole scaffold: Investigation of the C5- and C7-positions to enhance affinity.

scientific article published on 5 December 2017

Antioxidant properties of di-tert-butylhydroxylated flavonoids

scientific article published on 01 November 2000

Apolipoprotein E knockout mice over-expressing human tissue inhibitor of metalloproteinase 1 are protected against aneurysm formation but not against atherosclerotic plaque development

scientific article published on 24 August 2006

Carboline- and phenothiazine-derivated heterocycles as potent SIGMA-1 protein ligands

scientific article published on 18 October 2014

Corrigendum to “Evaluation and comparison of three different separation techniques for analysis of retroamide enantiomers and their biological evaluation against h -P2X7 receptor” [J. Chromatogr. B 986–987 (2015) 35–43]

scientific article published on 24 May 2016

Daily melatonin supplementation in mice increases atherosclerosis in proximal aorta

scientific article

Development and validation of a reversed-phase HPLC method for the quantification of paclitaxel in different PLGA nanocarriers

scientific article

Development of innovative paclitaxel-loaded small PLGA nanoparticles: study of their antiproliferative activity and their molecular interactions on prostatic cancer cells.

scientific article published on 21 May 2013

Di-tert-butylhydroxylated flavonoids protect endothelial cells against oxidized LDL-induced cytotoxicity.

scientific article published on January 2001

Differential toxicities of air (mO-LDL) or copper-oxidized LDLs (Cu-LDL) toward endothelial cells.

scientific article

Enantioseparation of pyroglutamide derivatives on polysaccharide based chiral stationary phases by high-performance liquid chromatography and supercritical fluid chromatography: a comparative study

scientific article published on 4 July 2014

Enhanced VDUP-1 gene expression by PPARgamma agonist induces apoptosis in human macrophage

scientific article published on 01 January 2008

Evaluation and comparison of three different separation techniques for analysis of retroamide enantiomers and their biological evaluation against h-P2X7 receptor

scientific article published on 09 February 2015

Extracellular human thioredoxin-1 inhibits lipopolysaccharide-induced interleukin-1beta expression in human monocyte-derived macrophages.

scientific article

Increased susceptibility of low-density lipoprotein to ex vivo oxidation in mice transgenic for human apolipoprotein B treated with 1 melatonin-related compound is not associated with atherosclerosis progression

scientific article published in September 2005

Oxidized phospholipids activate PPARα in a phospholipase A2-dependent manner

scientific article published on 01 April 2000

Ozonized low density lipoprotein (ozLDL) inhibits NF-kappaB and IRAK-1-associated signaling.

scientific article published on 19 October 2006

Perilipin, a potential substitute for adipophilin in triglyceride storage in human macrophages

scientific article published on 24 January 2006

Peroxisome proliferator-activated receptor-alpha activation as a mechanism of preventive neuroprotection induced by chronic fenofibrate treatment.

scientific article published in July 2003

Potent farnesyltransferase inhibitors with 1,4-diazepane scaffolds as novel destabilizing microtubule agents in hormone-resistant prostate cancer.

scientific article published on 7 February 2011

Pyroglutamide-Based P2X7 Receptor Antagonists Targeting Inflammatory Bowel Disease

scientific article published on 27 September 2019

REDD2 gene is upregulated by modified LDL or hypoxia and mediates human macrophage cell death.

scientific article published on 12 August 2004

Rosuvastatin reduces MMP-7 secretion by human monocyte-derived macrophages: potential relevance to atherosclerotic plaque stability.

scientific article

Scaffold hopping strategy toward original pyrazolines as selective CB2 receptor ligands

scientific article published on 26 October 2012

Synthesis and pharmacological evaluation of benzannulated derivatives as potent and selective sigma-1 protein ligands

scientific article

Systemic tissue inhibitor of metalloproteinase-1 gene delivery reduces neointimal hyperplasia in balloon-injured rat carotid artery

article

Targeting peroxisome proliferator-activated receptors (PPARs): development of modulators.

scientific article published on 27 February 2012

Thioredoxin-1 and its natural inhibitor, vitamin D3 up-regulated protein 1, are differentially regulated by PPARalpha in human macrophages

scientific article

Virtual screening of CB(2) receptor agonists from bayesian network and high-throughput docking: structural insights into agonist-modulated GPCR features.

scientific article

List of works by Christophe Furman

4-Oxo-1,4-dihydropyridines as selective CB₂ cannabinoid receptor ligands. Part 2: discovery of new agonists endowed with protective effect against experimental colitis.

6-Sulfonylbenzothiazolones as potential scaffolds for the design of 5-HT6 ligands

A High Concentration of Melatonin Inhibits In Vitro LDL Peroxidation But Not Oxidized LDL Toxicity Toward Cultured Endothelial Cells

Antagonists of the P2X7 receptor: mechanism of enantioselective recognition using highly sulfated and sulfobutylether cyclodextrins by capillary electrokinetic chromatography

Antagonists of the adenosine A2A receptor based on a 2-arylbenzoxazole scaffold: Investigation of the C5- and C7-positions to enhance affinity.

Antioxidant properties of di-tert-butylhydroxylated flavonoids

Apolipoprotein E knockout mice over-expressing human tissue inhibitor of metalloproteinase 1 are protected against aneurysm formation but not against atherosclerotic plaque development

Carboline- and phenothiazine-derivated heterocycles as potent SIGMA-1 protein ligands

Corrigendum to “Evaluation and comparison of three different separation techniques for analysis of retroamide enantiomers and their biological evaluation against h -P2X7 receptor” [J. Chromatogr. B 986–987 (2015) 35–43]

Daily melatonin supplementation in mice increases atherosclerosis in proximal aorta

Development and validation of a reversed-phase HPLC method for the quantification of paclitaxel in different PLGA nanocarriers

Development of innovative paclitaxel-loaded small PLGA nanoparticles: study of their antiproliferative activity and their molecular interactions on prostatic cancer cells.

Di-tert-butylhydroxylated flavonoids protect endothelial cells against oxidized LDL-induced cytotoxicity.

Differential toxicities of air (mO-LDL) or copper-oxidized LDLs (Cu-LDL) toward endothelial cells.

Enantioseparation of pyroglutamide derivatives on polysaccharide based chiral stationary phases by high-performance liquid chromatography and supercritical fluid chromatography: a comparative study

Enhanced VDUP-1 gene expression by PPARgamma agonist induces apoptosis in human macrophage

Evaluation and comparison of three different separation techniques for analysis of retroamide enantiomers and their biological evaluation against h-P2X7 receptor

Extracellular human thioredoxin-1 inhibits lipopolysaccharide-induced interleukin-1beta expression in human monocyte-derived macrophages.

Increased susceptibility of low-density lipoprotein to ex vivo oxidation in mice transgenic for human apolipoprotein B treated with 1 melatonin-related compound is not associated with atherosclerosis progression

Oxidized phospholipids activate PPARα in a phospholipase A2-dependent manner

Ozonized low density lipoprotein (ozLDL) inhibits NF-kappaB and IRAK-1-associated signaling.

Perilipin, a potential substitute for adipophilin in triglyceride storage in human macrophages

Peroxisome proliferator-activated receptor-alpha activation as a mechanism of preventive neuroprotection induced by chronic fenofibrate treatment.

Potent farnesyltransferase inhibitors with 1,4-diazepane scaffolds as novel destabilizing microtubule agents in hormone-resistant prostate cancer.

Pyroglutamide-Based P2X7 Receptor Antagonists Targeting Inflammatory Bowel Disease

REDD2 gene is upregulated by modified LDL or hypoxia and mediates human macrophage cell death.

Rosuvastatin reduces MMP-7 secretion by human monocyte-derived macrophages: potential relevance to atherosclerotic plaque stability.

Scaffold hopping strategy toward original pyrazolines as selective CB2 receptor ligands

Synthesis and pharmacological evaluation of benzannulated derivatives as potent and selective sigma-1 protein ligands

Systemic tissue inhibitor of metalloproteinase-1 gene delivery reduces neointimal hyperplasia in balloon-injured rat carotid artery

Targeting peroxisome proliferator-activated receptors (PPARs): development of modulators.

Thioredoxin-1 and its natural inhibitor, vitamin D3 up-regulated protein 1, are differentially regulated by PPARalpha in human macrophages

Virtual screening of CB(2) receptor agonists from bayesian network and high-throughput docking: structural insights into agonist-modulated GPCR features.