List of works - Mikel Oiarbide

A Concise beta-Lactam Route to Short Peptide Segments Containing beta,beta-Disubstituted beta-Amino Acids

scientific article published on 01 April 1998

A beta-lactam-based stereoselective access to beta,gamma-dihydroxy alpha-amino acid-derived peptides with either alpha,beta-like or unlike configurations.

scientific article published in June 2001

A concise synthesis of α-amino acid N-carboxy anhydrides of (2S,3S)-β-substituted serines

A strategy for the asymmetric aminohomologation of alpha, beta-dihydroxy aldehydes: application to the synthesis of the southwest tripeptide segment of echinocandin B.

scientific article

Alkylation of chiral alpha-hydroxy ketones derived from (1R)-(+)-camphor. An asymmetric variant of the classical acetylene route to carbonyl compounds

scientific article published on 01 October 2001

Asymmetric Assembly of All-Carbon Tertiary/Quaternary Nonadjacent Stereocenters through Organocatalytic Conjugate Addition of α-Cyanoacetates to a Methacrylate Equivalent.

scientific article published on 3 August 2016

Asymmetric synthesis of beta-mercapto carboxylic acid derivatives by intramolecular sulfur transfer in N-enoyl oxazolidine-2-thiones promoted by Lewis acids

scientific article published on 01 June 2001

Base-Catalyzed Asymmetric α-Functionalization of 2-(Cyanomethyl)azaarene N-Oxides Leading to Quaternary Stereocenters

scientific article published on 3 March 2016

Bifunctional Brønsted Base Catalyst Enables Regio-, Diastereo-, and Enantioselective Cα -Alkylation of β-Tetralones and Related Aromatic-Ring-Fused Cycloalkanones.

scientific article published on 18 January 2017

Brønsted Base Catalyzed One-Pot Synthesis of Stereodefined Six-Member Carbocycles Featuring Transient Trienolates and a Key Intramolecular 1,6-Addition

scientific article published on 30 August 2019

Camphor-based alpha-bromo ketones for the asymmetric darzens reaction

scientific article published on 01 December 2000

Catalytic Asymmetric Synthesis of Quaternary Barbituric Acids

scientific article published on 12 October 2017

Catalytic Enantioselective Synthesis of N,C(α),C(α)-Trisubstituted α-Amino Acid Derivatives Using 1H-Imidazol-4(5H)-ones as Key Templates.

scientific article

Catalytic Michael reactions of ketoesters with a camphor-derived acrylate equivalent: stereoselective access to all-carbon quaternary centers

scientific article published on 03 June 2008

Catalytic conjugate additions of geminal bis(sulfone)s: expanding the chemistry of sulfones as simple alkyl anion equivalents.

scientific article published in November 2009

Catalytic enantioselective aza-Henry reaction with broad substrate scope.

scientific article

Catalytic enantioselective conjugate addition of carbamates

scientific article published on 01 August 2004

Catalytic enantioselective quick route to aldol-tethered 1,6- and 1,7-enynes from ω-unsaturated aldehydes.

scientific article published on 3 October 2014

Conjugate addition of nitroalkanes to an acrylate equivalent. Stereocontrol at C-alpha of the nitro group through double catalytic activation

scientific article published on 01 September 2009

Construction of C--S bonds with a quaternary stereocenter through a formal michael reaction: asymmetric synthesis of tertiary thiols

scientific article published on 01 June 2004

Controlling the α/γ-Reactivity of Vinylogous Ketone Enolates in Organocatalytic Enantioselective Michael Reactions.

scientific article published on 30 May 2017

Copper-catalyzed enantioselective conjugate addition of dialkylzinc reagents to alpha'-oxy enones

scientific article published on 01 January 2008

Design and synthesis of a novel class of sugar-peptide hybrids: C-linked glyco beta-amino acids through a stereoselective "acetate" Mannich reaction as the key strategic element

scientific article

Development of a syn-Selective Mannich Reaction of Aldehydes with Propargylic Imines by Dual Catalysis: Asymmetric Synthesis of Functionalized Propargylic Amines

scientific article published on 13 April 2016

Enantio- and diastereoselective organocatalytic α-alkylation of aldehydes with 3-substituted 2-(bromomethyl)acrylates

scientific article published on 14 December 2011

Enantioselective Addition of Alkynyl Ketones to Nitroolefins Assisted by Brønsted Base/H-Bonding Catalysis

scientific article published on 27 February 2019

Enantioselective Synthesis of 5,5-Disubstituted Hydantoins by Brønsted Base/H-Bond Catalyst Assisted Michael Reactions of a Design Template.

scientific article published on 25 March 2018

Enantioselective Synthesis of Quaternary Δ4 - and Δ5 -Dehydroprolines Based on a Two-Step Formal [3+2] Cycloaddition of α-Aryl and α-Alkyl Isocyano(thio)acetates with Vinyl Ketones.

scientific article published on 28 July 2017

Enantioselective aza-Henry reactions assisted by Zn(II) and N-methylephedrine.

scientific article

Enantioselective construction of tetrasubstituted stereogenic carbons through Brønsted base catalyzed michael reactions: α'-hydroxy enones as key enoate equivalent

scientific article published on 09 December 2014

Enantioselective henry reactions under dual Lewis acid/amine catalysis using chiral amino alcohol ligands

scientific article published on 01 June 2005

From beta-lactams to alpha- and beta-amino acid derived peptides.

scientific article

Helical Oligourea Foldamers as Powerful Hydrogen Bonding Catalysts for Enantioselective C-C Bond-Forming Reactions

scientific article

Highly Diastereoselective Aldol Reactions with Camphor-Based Acetate Enolate Equivalents

scientific article published on 01 October 1999

Highly enantioselective Friedel-Crafts alkylations of pyrroles and indoles with alpha'-hydroxy enones under Cu(II)-simple bis(oxazoline) catalysis.

scientific article published in March 2005

Highly enantioselective conjugate additions of aldehydes to vinyl sulfones

scientific article published on 01 January 2009

Intramolecular sulfur transfer in N-enoyl oxazolidine-2-thiones promoted by Brønsted acids. Practical asymmetric synthesis of beta-mercapto carboxylic acids and mechanistic insights

scientific article published on 01 November 2006

Lewis acid catalyzed asymmetric cycloadditions of nitrones: alpha'-hydroxy enones as efficient reaction partners

scientific article published on 01 September 2005

N-(Diazoacetyl)oxazolidin-2-thiones as sulfur-donor reagents: asymmetric synthesis of thiiranes from aldehydes

scientific article published on 26 September 2012

Practical Synthesis of α-Amino AcidN-Carboxy Anhydrides of Polyhydroxylated α-Amino Acids from β-Lactam Frameworks. Model Studies toward the Synthesis of Directly Linked Peptidyl Nucleoside Antibiotics

article

The aldol addition reaction: an old transformation at constant rebirth

scientific article published on 01 January 2002

Towards Direct Mukaiyama‐Type Reactions Catalytic in Silicon ⬇️

scientific article published on 08 July 2011

Unveiling reliable catalysts for the asymmetric nitroaldol (Henry) reaction.

scientific article published in October 2004

alpha-Oxymethyl Ketone Enolates for the Asymmetric Mannich Reaction. From Acetylene and N-Alkoxycarbonylimines to beta-Amino Acids This work was supported by the University of the Basque Country, the Basque Government (Projects UPV 170.215-G47/98, E

scientific article published on 01 March 2000

α-Hydroxy Ketones as Masked Ester Donors in Brønsted Base Catalyzed Conjugate Additions to Nitroalkenes

scientific article published on 15 February 2018

α-Hydroxy ketones as useful templates in asymmetric reactions.

scientific article published on 17 April 2012

List of works by Mikel Oiarbide

A Concise beta-Lactam Route to Short Peptide Segments Containing beta,beta-Disubstituted beta-Amino Acids

A beta-lactam-based stereoselective access to beta,gamma-dihydroxy alpha-amino acid-derived peptides with either alpha,beta-like or unlike configurations.

A concise synthesis of α-amino acid N-carboxy anhydrides of (2S,3S)-β-substituted serines

A strategy for the asymmetric aminohomologation of alpha, beta-dihydroxy aldehydes: application to the synthesis of the southwest tripeptide segment of echinocandin B.

Alkylation of chiral alpha-hydroxy ketones derived from (1R)-(+)-camphor. An asymmetric variant of the classical acetylene route to carbonyl compounds

Asymmetric Assembly of All-Carbon Tertiary/Quaternary Nonadjacent Stereocenters through Organocatalytic Conjugate Addition of α-Cyanoacetates to a Methacrylate Equivalent.

Asymmetric synthesis of beta-mercapto carboxylic acid derivatives by intramolecular sulfur transfer in N-enoyl oxazolidine-2-thiones promoted by Lewis acids

Base-Catalyzed Asymmetric α-Functionalization of 2-(Cyanomethyl)azaarene N-Oxides Leading to Quaternary Stereocenters

Bifunctional Brønsted Base Catalyst Enables Regio-, Diastereo-, and Enantioselective Cα -Alkylation of β-Tetralones and Related Aromatic-Ring-Fused Cycloalkanones.

Brønsted Base Catalyzed One-Pot Synthesis of Stereodefined Six-Member Carbocycles Featuring Transient Trienolates and a Key Intramolecular 1,6-Addition

Camphor-based alpha-bromo ketones for the asymmetric darzens reaction

Catalytic Asymmetric Synthesis of Quaternary Barbituric Acids

Catalytic Enantioselective Synthesis of N,C(α),C(α)-Trisubstituted α-Amino Acid Derivatives Using 1H-Imidazol-4(5H)-ones as Key Templates.

Catalytic Michael reactions of ketoesters with a camphor-derived acrylate equivalent: stereoselective access to all-carbon quaternary centers

Catalytic conjugate additions of geminal bis(sulfone)s: expanding the chemistry of sulfones as simple alkyl anion equivalents.

Catalytic enantioselective aza-Henry reaction with broad substrate scope.

Catalytic enantioselective conjugate addition of carbamates

Catalytic enantioselective quick route to aldol-tethered 1,6- and 1,7-enynes from ω-unsaturated aldehydes.

Conjugate addition of nitroalkanes to an acrylate equivalent. Stereocontrol at C-alpha of the nitro group through double catalytic activation

Construction of C--S bonds with a quaternary stereocenter through a formal michael reaction: asymmetric synthesis of tertiary thiols

Controlling the α/γ-Reactivity of Vinylogous Ketone Enolates in Organocatalytic Enantioselective Michael Reactions.

Copper-catalyzed enantioselective conjugate addition of dialkylzinc reagents to alpha'-oxy enones

Design and synthesis of a novel class of sugar-peptide hybrids: C-linked glyco beta-amino acids through a stereoselective "acetate" Mannich reaction as the key strategic element

Development of a syn-Selective Mannich Reaction of Aldehydes with Propargylic Imines by Dual Catalysis: Asymmetric Synthesis of Functionalized Propargylic Amines

Enantio- and diastereoselective organocatalytic α-alkylation of aldehydes with 3-substituted 2-(bromomethyl)acrylates

Enantioselective Addition of Alkynyl Ketones to Nitroolefins Assisted by Brønsted Base/H-Bonding Catalysis

Enantioselective Synthesis of 5,5-Disubstituted Hydantoins by Brønsted Base/H-Bond Catalyst Assisted Michael Reactions of a Design Template.

Enantioselective Synthesis of Quaternary Δ4 - and Δ5 -Dehydroprolines Based on a Two-Step Formal [3+2] Cycloaddition of α-Aryl and α-Alkyl Isocyano(thio)acetates with Vinyl Ketones.

Enantioselective aza-Henry reactions assisted by Zn(II) and N-methylephedrine.

Enantioselective construction of tetrasubstituted stereogenic carbons through Brønsted base catalyzed michael reactions: α'-hydroxy enones as key enoate equivalent

Enantioselective henry reactions under dual Lewis acid/amine catalysis using chiral amino alcohol ligands

From beta-lactams to alpha- and beta-amino acid derived peptides.

Helical Oligourea Foldamers as Powerful Hydrogen Bonding Catalysts for Enantioselective C-C Bond-Forming Reactions

Highly Diastereoselective Aldol Reactions with Camphor-Based Acetate Enolate Equivalents

Highly enantioselective Friedel-Crafts alkylations of pyrroles and indoles with alpha'-hydroxy enones under Cu(II)-simple bis(oxazoline) catalysis.

Highly enantioselective conjugate additions of aldehydes to vinyl sulfones

Intramolecular sulfur transfer in N-enoyl oxazolidine-2-thiones promoted by Brønsted acids. Practical asymmetric synthesis of beta-mercapto carboxylic acids and mechanistic insights

Lewis acid catalyzed asymmetric cycloadditions of nitrones: alpha'-hydroxy enones as efficient reaction partners

N-(Diazoacetyl)oxazolidin-2-thiones as sulfur-donor reagents: asymmetric synthesis of thiiranes from aldehydes

Practical Synthesis of α-Amino AcidN-Carboxy Anhydrides of Polyhydroxylated α-Amino Acids from β-Lactam Frameworks. Model Studies toward the Synthesis of Directly Linked Peptidyl Nucleoside Antibiotics

The aldol addition reaction: an old transformation at constant rebirth

Towards Direct Mukaiyama‐Type Reactions Catalytic in Silicon ⬇️

Unveiling reliable catalysts for the asymmetric nitroaldol (Henry) reaction.

alpha-Oxymethyl Ketone Enolates for the Asymmetric Mannich Reaction. From Acetylene and N-Alkoxycarbonylimines to beta-Amino Acids This work was supported by the University of the Basque Country, the Basque Government (Projects UPV 170.215-G47/98, E

α-Hydroxy Ketones as Masked Ester Donors in Brønsted Base Catalyzed Conjugate Additions to Nitroalkenes

α-Hydroxy ketones as useful templates in asymmetric reactions.