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List of works by Irena Audzeyenka

Cathepsin C is a novel mediator of podocyte and renal injury induced by hyperglycemia

scientific article published on 14 April 2020

Combined effect of insulin and high glucose concentration on albumin permeability in cultured rat podocytes.

scientific article published on 15 April 2015

Enhancement of cGMP-dependent pathway activity ameliorates hyperglycemia-induced decrease in SIRT1-AMPK activity in podocytes: Impact on glucose uptake and podocyte function

scientific article published in December 2022

Expression of membrane-bound NPP-type ecto-phosphodiesterases in rat podocytes cultured at normal and high glucose concentrations

scientific article

Extracellular ATP modulates podocyte function through P2Y purinergic receptors and pleiotropic effects on AMPK and cAMP/PKA signaling pathways

scientific article published on 22 October 2020

Extracellular purines' action on glomerular albumin permeability in isolated rat glomeruli: insights into the pathogenesis of albuminuria

scientific article

High glucose concentration affects the oxidant-antioxidant balance in cultured mouse podocytes

scientific article published on 01 June 2011

High glucose increases glomerular filtration barrier permeability by activating protein kinase G type Iα subunits in a Nox4-dependent manner.

scientific article published on 13 September 2013

Hyperglycemia alters mitochondrial respiration efficiency and mitophagy in human podocytes

scientific article

Hyperglycemic environment disrupts phosphate transporter function and promotes calcification processes in podocytes and isolated glomeruli

scientific article published on 12 February 2022

Inhibition of phosphodiesterase 5A by tadalafil improves SIRT1 expression and activity in insulin-resistant podocytes

scientific article published in May 2023

Insulin controls cytoskeleton reorganization and filtration barrier permeability via the PKGIα-Rac1-RhoA crosstalk in cultured rat podocytes

scientific article published in September 2022

Insulin increases filtration barrier permeability via TRPC6-dependent activation of PKGIα signaling pathways.

scientific article published on 2 March 2017

Insulin increases glomerular filtration barrier permeability through PKGIα-dependent mobilization of BKCa channels in cultured rat podocytes.

scientific article published on 4 May 2015

Intracellular calcium signaling regulates glomerular filtration barrier permeability: the role of the PKGIα-dependent pathway.

scientific article published on 27 May 2016

Involvement of nitric oxide synthase/nitric oxide pathway in the regulation of SIRT1–AMPK crosstalk in podocytes: Impact on glucose uptake

scientific article

Involvement of the AMPK-PTEN pathway in insulin resistance induced by high glucose in cultured rat podocytes

scientific article

Metformin overcomes high glucose-induced insulin resistance of podocytes by pleiotropic effects on SIRT1 and AMPK.

scientific article

Metformin reduces TRPC6 expression through AMPK activation and modulates cytoskeleton dynamics in podocytes under diabetic conditions

scientific article published on 25 November 2019

PTEN-induced kinase 1 deficiency alters albumin permeability and insulin signaling in podocytes

scientific article published on 9 May 2022

Pit 1 transporter (SLC20A1) as a key factor in the NPP1‐mediated inhibition of insulin signaling in human podocytes

scientific article published on 3 June 2023

Reactive oxygen species are involved in insulin-dependent regulation of autophagy in primary rat podocytes.

scientific article

Regulation of podocytes function by AMP-activated protein kinase

scientific article published on 08 August 2020

Role of Klotho in Hyperglycemia: Its Levels and Effects on Fibroblast Growth Factor Receptors, Glycolysis, and Glomerular Filtration ⬇️

journal article from 'International Journal of Molecular Sciences' published in 2021

Role of L-lactate as an energy substrate in primary rat podocytes under physiological and glucose deprivation conditions

scientific article published in June 2023

Role of lysosomes in insulin signaling and glucose uptake in cultured rat podocytes

scientific article published in October 2023

SIRT1-AMPK crosstalk is involved in high glucose-dependent impairment of insulin responsiveness in primary rat podocytes.

scientific article published on 8 November 2016

The PKGIα-Rac1 pathway is a novel regulator of insulin-dependent glucose uptake in cultured rat podocytes

scientific article published on 26 November 2020

The PKGIα/VASP pathway is involved in insulin- and high glucose-dependent regulation of albumin permeability in cultured rat podocytes

scientific article published on 02 June 2020

The Role of PKGIα and AMPK Signaling Interplay in the Regulation of Albumin Permeability in Cultured Rat Podocytes

scientific article published in 2023

The Role of PKGIα and AMPK Signaling Interplay in the Regulation of Albumin Permeability in Cultured Rat Podocytes

scientific article published on 16 February 2023

The TRPC6-AMPK Pathway is Involved in Insulin-Dependent Cytoskeleton Reorganization and Glucose Uptake in Cultured Rat Podocytes

scientific article published on 19 November 2018

Viability of primary cultured podocytes is associated with extracellular high glucose-dependent autophagy downregulation.

scientific article

β-Aminoisobutyric acid (L-BAIBA) is a novel regulator of mitochondrial biogenesis and respiratory function in human podocytes

β-Aminoisobutyric acid (L-BAIBA) is a novel regulator of mitochondrial biogenesis and respiratory function in human podocytes

scientific article published on 14 January 2023

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