List of works - Mahmoud ElHefnawi

A cellular screening platform, stably expressing DENV2 NS5, defines a novel anti-DENV mechanism of action of Apigenin based on STAT2 activation

scientific article published in June 2023

A review study: Computational techniques for expecting the impact of non-synonymous single nucleotide variants in human diseases

article

Accurate classification and hemagglutinin amino acid signatures for influenza A virus host-origin association and subtyping.

scientific article published on 22 December 2013

Altered expression of WFS1 and NOTCH2 genes associated with diabetic nephropathy in T2DM patients.

scientific article

An integrated methodology for mining promiscuous proteins: a case study of an integrative bioinformatics approach for hepatitis C virus non-structural 5A protein

scientific article published on January 2010

An integrative meta-analysis of microRNAs in hepatocellular carcinoma.

scientific article

Bioinformatics functional analysis of let-7a, miR-34a, and miR-199a/b reveals novel insights into immune system pathways and cancer hallmarks for hepatocellular carcinoma

scientific article published on 01 May 2018

Computational Identification of Tissue-Specific Splicing Regulatory Elements in Human Genes from RNA-Seq Data

scientific article

Correlating novel variable and conserved motifs in the Hemagglutinin protein with significant biological functions.

scientific article published on 5 August 2008

DeNovo: virus-host sequence-based protein-protein interaction prediction.

scientific article

Down-regulation of circulating microRNA let-7a in Egyptian smokers

scientific article published on 12 February 2018

Ensemble-based classification approach for micro-RNA mining applied on diverse metagenomic sequences

scientific article

Evaluation of computational techniques for predicting non-synonymous single nucleotide variants pathogenicity

scientific article published on 26 May 2018

Genetic variability of the core protein in hepatitis C virus genotype 4 in Saudi Arabian patients and its implication on pegylated interferon and ribavirin therapy

scientific article

Hepatitis C virus genotype 1: how genetic variability of the core protein affects the response to pegylated-interferon and ribavirin therapy.

scientific article published on 28 October 2013

Hsa-miR-195 targets PCMT1 in hepatocellular carcinoma that increases tumor life span.

scientific article published on 14 August 2014

Identification of novel conserved functional motifs across most Influenza A viral strains

scientific article

In silico identification of potential key regulatory factors in smoking-induced lung cancer.

scientific article

MicroRNA expression analysis in endometriotic serum treated mesenchymal stem cells

scientific article

MicroRNA-150 down Regulation in Acute Myeloid Leukaemia Patients and Its Prognostic Implication

scientific article published on 19 November 2018

MicroTarget: MicroRNA target gene prediction approach with application to breast cancer.

scientific article published on 2 May 2017

Modified gold nanoparticles for intracellular delivery of anti-liver cancer siRNA.

scientific article published on 29 March 2016

Multiple virtual screening approaches for finding new hepatitis C virus RNA-dependent RNA polymerase inhibitors: structure-based screens and molecular dynamics for the pursue of new poly pharmacological inhibitors

scientific article

MysiRNA-designer: a workflow for efficient siRNA design

scientific article

MysiRNA: improving siRNA efficacy prediction using a machine-learning model combining multi-tools and whole stacking energy (ΔG).

scientific article published on 25 February 2012

Natural genetic engineering of hepatitis C virus NS5A for immune system counterattack.

scientific article published in October 2009

New benzimidazoles and their antitumor effects with Aurora A kinase and KSP inhibitory activities.

scientific article

Part I: Synthesis, cancer chemopreventive activity and molecular docking study of novel quinoxaline derivatives ⬇️

scientific article published on November 24, 2010

Rational drug design for identifying novel multi-target inhibitors for hepatocellular carcinoma.

scientific article

Synthesis, pharmacological activity evaluation and molecular modeling of new polynuclear heterocyclic compounds containing benzimidazole derivatives.

scientific article

The design of optimal therapeutic small interfering RNA molecules targeting diverse strains of influenza A virus

scientific article published on 11 October 2011

Whole genome sequencing and bioinformatics analysis of two Egyptian genomes

article

List of works by Mahmoud ElHefnawi

A cellular screening platform, stably expressing DENV2 NS5, defines a novel anti-DENV mechanism of action of Apigenin based on STAT2 activation

A review study: Computational techniques for expecting the impact of non-synonymous single nucleotide variants in human diseases

Accurate classification and hemagglutinin amino acid signatures for influenza A virus host-origin association and subtyping.

Altered expression of WFS1 and NOTCH2 genes associated with diabetic nephropathy in T2DM patients.

An integrated methodology for mining promiscuous proteins: a case study of an integrative bioinformatics approach for hepatitis C virus non-structural 5A protein

An integrative meta-analysis of microRNAs in hepatocellular carcinoma.

Bioinformatics functional analysis of let-7a, miR-34a, and miR-199a/b reveals novel insights into immune system pathways and cancer hallmarks for hepatocellular carcinoma

Computational Identification of Tissue-Specific Splicing Regulatory Elements in Human Genes from RNA-Seq Data

Correlating novel variable and conserved motifs in the Hemagglutinin protein with significant biological functions.

DeNovo: virus-host sequence-based protein-protein interaction prediction.

Down-regulation of circulating microRNA let-7a in Egyptian smokers

Ensemble-based classification approach for micro-RNA mining applied on diverse metagenomic sequences

Evaluation of computational techniques for predicting non-synonymous single nucleotide variants pathogenicity

Genetic variability of the core protein in hepatitis C virus genotype 4 in Saudi Arabian patients and its implication on pegylated interferon and ribavirin therapy

Hepatitis C virus genotype 1: how genetic variability of the core protein affects the response to pegylated-interferon and ribavirin therapy.

Hsa-miR-195 targets PCMT1 in hepatocellular carcinoma that increases tumor life span.

Identification of novel conserved functional motifs across most Influenza A viral strains

In silico identification of potential key regulatory factors in smoking-induced lung cancer.

MicroRNA expression analysis in endometriotic serum treated mesenchymal stem cells

MicroRNA-150 down Regulation in Acute Myeloid Leukaemia Patients and Its Prognostic Implication

MicroTarget: MicroRNA target gene prediction approach with application to breast cancer.

Modified gold nanoparticles for intracellular delivery of anti-liver cancer siRNA.

Multiple virtual screening approaches for finding new hepatitis C virus RNA-dependent RNA polymerase inhibitors: structure-based screens and molecular dynamics for the pursue of new poly pharmacological inhibitors

MysiRNA-designer: a workflow for efficient siRNA design

MysiRNA: improving siRNA efficacy prediction using a machine-learning model combining multi-tools and whole stacking energy (ΔG).

Natural genetic engineering of hepatitis C virus NS5A for immune system counterattack.

New benzimidazoles and their antitumor effects with Aurora A kinase and KSP inhibitory activities.

Part I: Synthesis, cancer chemopreventive activity and molecular docking study of novel quinoxaline derivatives ⬇️

Rational drug design for identifying novel multi-target inhibitors for hepatocellular carcinoma.

Synthesis, pharmacological activity evaluation and molecular modeling of new polynuclear heterocyclic compounds containing benzimidazole derivatives.

The design of optimal therapeutic small interfering RNA molecules targeting diverse strains of influenza A virus

Whole genome sequencing and bioinformatics analysis of two Egyptian genomes