List of works - Brenda M Luken

Activated protein C cofactor function of protein S: a critical role for Asp95 in the EGF1-like domain

scientific article

Amino acid regions 572-579 and 657-666 of the spacer domain of ADAMTS13 provide a common antigenic core required for binding of antibodies in patients with acquired TTP.

scientific article

An autoantibody epitope comprising residues R660, Y661, and Y665 in the ADAMTS13 spacer domain identifies a binding site for the A2 domain of VWF

scientific article

Antibodies against the CUB1-2 domains of ADAMTS13 in a patient with benign monoclonal gammopathy: no causal relationship

scientific article published on 01 July 2007

Autoregulation of von Willebrand factor function by a disulfide bond switch.

scientific article published on 28 February 2018

Circulating ADAMTS-13-von Willebrand factor complexes: an enzyme on demand

scientific article published on 18 September 2009

Complexes of factor VII-activating protease with plasminogen activator inhibitor-1 in human sepsis

scientific article published on 20 March 2014

Conformational activation of ADAMTS13.

scientific article

Control of VWF A2 domain stability and ADAMTS13 access to the scissile bond of full-length VWF.

scientific article published on 20 February 2014

Differential effects of the loss of intrachain- versus interchain-disulfide bonds in the cystine-knot domain of von Willebrand factor on the clinical phenotype of von Willebrand disease

scientific article published on 01 December 2006

Evidence for a role of anti-ADAMTS13 autoantibodies despite normal ADAMTS13 activity in recurrent thrombotic thrombocytopenic purpura

scientific article

FSAP-mediated nucleosome release from late apoptotic cells is inhibited by autoantibodies present in SLE

scientific article published on 22 December 2015

High VWF, low ADAMTS13, and oral contraceptives increase the risk of ischemic stroke and myocardial infarction in young women

scientific article published on 22 November 2011

Humoral immune response to ADAMTS13 in acquired thrombotic thrombocytopenic purpura ⬇️

scientific article published on July 1, 2011

Multiple B-cell clones producing antibodies directed to the spacer and disintegrin/thrombospondin type-1 repeat 1 (TSP1) of ADAMTS13 in a patient with acquired thrombotic thrombocytopenic purpura.

scientific article published on 8 August 2006

The importance of vicinal cysteines, C1669 and C1670, for von Willebrand factor A2 domain function

scientific article

The spacer domain of ADAMTS13 contains a major binding site for antibodies in patients with thrombotic thrombocytopenic purpura

scientific article

Unraveling the scissile bond: how ADAMTS13 recognizes and cleaves von Willebrand factor.

scientific article published on 29 June 2011

List of works by Brenda M Luken

Activated protein C cofactor function of protein S: a critical role for Asp95 in the EGF1-like domain

Amino acid regions 572-579 and 657-666 of the spacer domain of ADAMTS13 provide a common antigenic core required for binding of antibodies in patients with acquired TTP.

An autoantibody epitope comprising residues R660, Y661, and Y665 in the ADAMTS13 spacer domain identifies a binding site for the A2 domain of VWF

Antibodies against the CUB1-2 domains of ADAMTS13 in a patient with benign monoclonal gammopathy: no causal relationship

Autoregulation of von Willebrand factor function by a disulfide bond switch.

Circulating ADAMTS-13-von Willebrand factor complexes: an enzyme on demand

Complexes of factor VII-activating protease with plasminogen activator inhibitor-1 in human sepsis

Conformational activation of ADAMTS13.

Control of VWF A2 domain stability and ADAMTS13 access to the scissile bond of full-length VWF.

Differential effects of the loss of intrachain- versus interchain-disulfide bonds in the cystine-knot domain of von Willebrand factor on the clinical phenotype of von Willebrand disease

Evidence for a role of anti-ADAMTS13 autoantibodies despite normal ADAMTS13 activity in recurrent thrombotic thrombocytopenic purpura

FSAP-mediated nucleosome release from late apoptotic cells is inhibited by autoantibodies present in SLE

High VWF, low ADAMTS13, and oral contraceptives increase the risk of ischemic stroke and myocardial infarction in young women

Humoral immune response to ADAMTS13 in acquired thrombotic thrombocytopenic purpura ⬇️

Multiple B-cell clones producing antibodies directed to the spacer and disintegrin/thrombospondin type-1 repeat 1 (TSP1) of ADAMTS13 in a patient with acquired thrombotic thrombocytopenic purpura.

The importance of vicinal cysteines, C1669 and C1670, for von Willebrand factor A2 domain function

The spacer domain of ADAMTS13 contains a major binding site for antibodies in patients with thrombotic thrombocytopenic purpura

Unraveling the scissile bond: how ADAMTS13 recognizes and cleaves von Willebrand factor.