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List of works by Marc Ruel

(18)F-FDG cell labeling may underestimate transplanted cell homing: more accurate, efficient, and stable cell labeling with hexadecyl-4-[(18)F]fluorobenzoate for in vivo tracking of transplanted human progenitor cells by positron emission tomography

scientific article

3-dimensional structures to enhance cell therapy and engineer contractile tissue.

scientific article published on February 2010

A collagen–chitosan hydrogel for endothelial differentiation and angiogenesis.

scientific article published in October 2010

A method to distinguish between gaseous and solid cerebral emboli in patients with prosthetic heart valves.

scientific article published on 25 October 2008

Activation of pulmonary mitogen-activated protein kinases during cardiopulmonary bypass

scientific article published on 01 November 2003

Adverse effects associated with transcatheter aortic valve implantation: a meta-analysis of contemporary studies

scientific article published in January 2013

An update on mechanical circulatory support for heart failure therapy.

scientific article published on March 2014

Anticoagulation strategies for left ventricular assist devices.

scientific article published on 08 January 2015

Aortic valve cusp shearing and migration into the left main coronary artery during transcatheter aortic valve implantation

scientific article published on 17 May 2012

Apico-Aortic Conduit for severe aortic stenosis: Technique, applications, and systematic review.

scientific article published on 07 July 2010

Aspirin plus clopidogrel versus aspirin alone after coronary artery bypass grafting: the clopidogrel after surgery for coronary artery disease (CASCADE) Trial.

scientific article published on 6 December 2010

Avoiding prosthesis-patient mismatch in the elderly: options other than mechanical prostheses.

scientific article

CD117-positive cells and mast cells in adult human cardiac valves--observations and implications for the creation of bioengineered grafts.

scientific article published on January 2006

Can minimally invasive coronary artery bypass grafting be initiated and practiced safely?: a learning curve analysis

scientific article published in November 2013

Cardiopulmonary bypass reduces peripheral microvascular contractile function by inhibition of mitogen-activated protein kinase activity

scientific article published in August 2003

Cardiovascular Surgery Supplement.

scientific article

Cardiovascular progenitor-derived extracellular vesicles recapitulate the beneficial effects of their parent cells in the treatment of chronic heart failure.

scientific article published on 19 January 2016

Cell-based vasculogenic studies in preclinical models of chronic myocardial ischaemia and hibernation.

scientific article published on 21 December 2012

Centrifugal pump and roller pump in adult cardiac surgery: a meta-analysis of randomized controlled trials.

scientific article published on 16 July 2012

Circuits with surface modifying additive alter the haemodynamic response to cardiopulmonary bypass

scientific article published on 01 March 1999

Clinical Impact of Changes in Left Ventricular Function After Aortic Valve Replacement: Analysis From 3112 Patients.

scientific article published on August 2015

Clinical and echocardiographic impact of functional tricuspid regurgitation repair at the time of mitral valve replacement

scientific article published on 01 October 2009

Clinical and echocardiographic outcomes after repair of mitral valve bileaflet prolapse due to myxomatous disease

scientific article published on 04 February 2012

Clinical evaluation of functional mitral stenosis after mitral valve repair for degenerative disease: potential affect on surgical strategy.

scientific article published on 26 September 2013

Clinical impact of mild acute kidney injury after cardiac surgery.

scientific article published on 31 July 2014

Clinical outcomes of treatment by percutaneous coronary intervention versus coronary artery bypass graft surgery in patients with chronic kidney disease undergoing index revascularization in Ontario

scientific article published on January 2015

Clinically relevant extracellular-matrix scaffolds for cell transplantation and vascular repair.

scientific article published in May 2012

Clopidogrel after coronary artery bypass graft surgery: insufficient evidence

scientific article published on 01 August 2011

Clopidogrel is safe early after on- and off-pump coronary artery bypass surgery.

scientific article published in November 2007

Collagen matrix-induced expression of integrin αVβ3 in circulating angiogenic cells can be targeted by matricellular protein CCN1 to enhance their function.

scientific article published on 2 December 2014

Collagen scaffolds with or without the addition of RGD peptides support cardiomyogenesis after aggregation of mouse embryonic stem cells.

scientific article

Collagen-based matrices improve the delivery of transplanted circulating progenitor cells: development and demonstration by ex vivo radionuclide cell labeling and in vivo tracking with positron-emission tomography.

scientific article published in November 2008

Comparative effects of mesenchymal progenitor cells, endothelial progenitor cells, or their combination on myocardial infarct regeneration and cardiac function.

scientific article published in November 2007

Comparison of coronary artery bypass surgery and percutaneous coronary intervention in patients with diabetes: a meta-analysis of randomised controlled trials

scientific article published on 13 September 2013

Comparison of hemodynamic performance of self-expandable CoreValve versus balloon-expandable Edwards SAPIEN aortic valves inserted by catheter for aortic stenosis.

scientific article

Comparison of vascular endothelial growth factor and fibroblast growth factor-2 in a swine model of endothelial dysfunction.

scientific article published on 16 January 2008

Contemporary midterm echocardiographic outcomes of Bentall procedure and aortic valve sparing root replacement

scientific article published on 24 June 2014

Correlates of saphenous vein graft hyperplasia and occlusion 1 year after coronary artery bypass grafting: analysis from the CASCADE randomized trial.

scientific article published on September 2013

Current readings: status of tricuspid valve repair.

scientific article published on January 2013

Delayed thrombin generation with hirudin anticoagulation during prolonged cardiopulmonary bypass

scientific article

Determinants of left ventricular dysfunction after repair of chronic asymptomatic mitral regurgitation

scientific article published on 06 November 2014

Development of reporter gene imaging techniques for long-term assessment of human circulating angiogenic cells.

scientific article published on 18 March 2015

Differential effects on the mesenteric microcirculatory response to vasopressin and phenylephrine after cardiopulmonary bypass

scientific article published on 01 March 2007

Does high-density lipoprotein influence the development of saphenous vein graft disease after coronary bypass surgery?: exploratory analysis from the CASCADE trial.

scientific article published on 10 July 2013

Dual antiplatelet therapy use by Canadian cardiac surgeons.

scientific article published on 28 August 2015

Early Surgery for Infective Endocarditis

scientific article published on 01 October 2012

Effects of L-arginine on fibroblast growth factor 2-induced angiogenesis in a model of endothelial dysfunction.

scientific article

Effects of methylprednisolone and a biocompatible copolymer circuit on blood activation during cardiopulmonary bypass

scientific article

Effects of off-pump versus on-pump coronary artery bypass grafting on function and viability of circulating endothelial progenitor cells

scientific article published on 01 September 2005

Endogenous myocardial angiogenesis and revascularization using a gastric submucosal patch

scientific article published on 01 May 2003

Enhanced freedom from prosthesis-patient mismatch with transcatheter aortic valve replacement: More to aortic regurgitation than meets the eye?

scientific article published on 10 December 2015

Enlargement of the small aortic root during aortic valve replacement: is there a benefit?

scientific article published in January 2008

Ex vivo generation of a highly potent population of circulating angiogenic cells using a collagen matrix.

scientific article

Exploiting extracellular matrix-stem cell interactions: a review of natural materials for therapeutic muscle regeneration.

scientific article published on 19 October 2011

First direct aortic retrievable transcatheter aortic valve implantation in humans

scientific article published on 22 July 2014

From genes to regenerative medicine: approaches in development.

scientific article published in November 2008

Gender differences in outcomes following cardiac surgery: implications for managing patients with mitral valve disease.

scientific article published on 08 January 2015

Gender differences in the long-term outcomes after valve replacement surgery.

scientific article published on 24 July 2008

Gene expression profile after cardiopulmonary bypass and cardioplegic arrest

scientific article published in November 2003

Generation of CD133+ cells from CD133- peripheral blood mononuclear cells and their properties

scientific article published on 10 March 2006

Genetics and genomics for the prevention and treatment of cardiovascular disease: update: a scientific statement from the American Heart Association

scientific article published on 02 December 2013

Handsewn proximal anastomoses onto the ascending aorta through a small left thoracotomy during minimally invasive multivessel coronary artery bypass grafting: a stepwise approach to safety and reproducibility

scientific article published on 01 January 2012

Heart valve prosthesis selection in patients with end-stage renal disease requiring dialysis: a systematic review and meta-analysis

scientific article published on 11 October 2011

High flow rates during modified ultrafiltration decrease cerebral blood flow velocity and venous oxygen saturation in infants

scientific article published on 01 July 2005

High-risk mitral valve surgery: what is the role of risk calculators?

scientific article published on March 2014

Highlights from the 2008 American Heart Association scientific session

scientific article published on 01 March 2009

Human blood and cardiac stem cells synergize to enhance cardiac repair when cotransplanted into ischemic myocardium.

scientific article published on September 2013

Hybrid approach for coronary artery revascularization: where do we stand?

scientific article

Hyperglycemia inhibits cardiac stem cell-mediated cardiac repair and angiogenic capacity

scientific article published on September 2014

ISMICS Consensus Conference and Statements of Randomized Controlled Trials of Off-Pump Versus Conventional Coronary Artery Bypass Surgery

scientific article published on 12 September 2015

Impact of Preexisting Left Bundle Branch Block in Transcatheter Aortic Valve Replacement Recipients

scientific article published on 01 November 2018

Impact of clopidogrel plus aspirin versus aspirin alone on the progression of native coronary artery disease after bypass surgery: analysis from the Clopidogrel After Surgery for Coronary Artery DiseasE (CASCADE) randomized trial

scientific article published on September 2014

Impact of mitral annular calcification on early and late outcomes following mitral valve repair of myxomatous degeneration.

scientific article published on 14 April 2013

Impact of statin use on outcomes after coronary artery bypass graft surgery

scientific article published on 13 October 2008

Impact of subglottic suctioning on the incidence of pneumonia after cardiac surgery: a retrospective observational study.

scientific article published on 29 August 2014

Impairment of human cell-based vasculogenesis in rats by hypercholesterolemia-induced endothelial dysfunction and rescue with L-arginine supplementation

scientific article published in January 2010

Improving cell engraftment with tissue engineering.

scientific article published in January 2008

Infected right ventricular myxoma and pulmonary valve endocarditis

scientific article published on 01 July 2007

Inhibition of the cardiac angiogenic response to exogenous vascular endothelial growth factor

scientific article published on 01 August 2004

Injectable small intestine submucosal extracellular matrix in an acute myocardial infarction model

scientific article published on 29 September 2013

Interventional valve surgery: building a team and working together.

scientific article published on January 2010

Intracardiac ultrasonic suture welding for knotless mitral valve replacement

scientific article published on 01 February 2002

Intraoperative indocyanine green angiography: ready for prime time?

scientific article published in February 2007

Invited Commentary

Invited Commentary

Invited commentary

Invited commentary

Invited commentary

Invited commentary

Invited commentary

Invited commentary

Is Aortic Valve Repair Reproducible? Analysis of the Learning Curve for Aortic Valve Repair.

scientific article published on 28 May 2015

Knowledge, attitudes, and practice patterns in surgical management of bicuspid aortopathy: a survey of 100 cardiac surgeons.

scientific article published on 26 August 2013

Late cardiac death in patients undergoing transcatheter aortic valve replacement: incidence and predictors of advanced heart failure and sudden cardiac death.

scientific article published on February 2015

Late incidence and determinants of stroke after aortic and mitral valve replacement

scientific article (publication date: July 2004)

Late incidence and predictors of persistent or recurrent heart failure in patients with mitral prosthetic valves.

scientific article published in August 2004

Leaflet resection versus leaflet preservation for repair of degenerative mitral regurgitation: Does it matter how the mitral valve is repaired?

scientific article

Left ventricular assist device in the management of refractory electrical storm.

scientific article published on 8 August 2014

Left ventricular assist device outflow graft disconnection

scientific article

Letter by Al-Atassi et al Regarding Article, "Cost-Effectiveness of Percutaneous Coronary Intervention With Drug-Eluting Stents Versus Bypass Surgery for Patients With 3-Vessel or Left Main Coronary Artery Disease: Final Results From the Synergy Bet

scientific article

Letter by Toeg et al regarding article, "Outcomes with coronary artery bypass graft surgery versus percutaneous coronary intervention for patients with diabetes mellitus: can newer generation drug-eluting stents bridge the gap?".

scientific article

Long-term clinical and hemodynamic performance of the Hancock II versus the Perimount aortic bioprostheses

scientific article published on 01 September 2010

Long-term effects of surgical angiogenic therapy with fibroblast growth factor 2 protein

scientific article published on 01 July 2002

Long-term evaluation of biological versus mechanical prosthesis use at reoperative aortic valve replacement

scientific article published on 29 September 2011

Long-term outcomes after valve replacement for low-gradient aortic stenosis: impact of prosthesis-patient mismatch

scientific article published in July 2006

Long-term outcomes of valve replacement with modern prostheses in young adults.

scientific article published on 30 December 2004

Malignant invasion of sternotomy incision after cardiac operation

scientific article published on 01 April 2010

Mechanical valve thrombosis with dabigatran

scientific article published on 26 September 2012

Mesenchymal Stem Cells for Cardiovascular Regeneration

scientific article published on August 1, 2011

Minimally invasive coronary artery bypass grafting via a small thoracotomy versus off-pump: a case-matched study.

scientific article

Minimally invasive coronary bypass in a patient with metal allergy

scientific article published on 03 December 2014

Mitogen-activated protein kinase pathways and cardiac surgery.

scientific article published on March 2004

Mitral valve replacement is a viable alternative to mitral valve repair for ischemic mitral regurgitation: a case-matched study

scientific article published on 01 October 2011

Myosin phosphatase modulates the cardiac cell fate by regulating the subcellular localization of Nkx2.5 in a Wnt/Rho-associated protein kinase-dependent pathway.

scientific article published on 20 November 2012

Natural history and management of aortocoronary saphenous vein graft aneurysms: a systematic review of published cases.

scientific article published on October 2012

Natural history and predictors of outcome in patients with concomitant functional mitral regurgitation at the time of aortic valve replacement.

scientific article

Normalization of coronary microvascular reactivity and improvement in myocardial perfusion by surgical vascular endothelial growth factor therapy combined with oral supplementation of l-arginine in a porcine model of endothelial dysfunction.

scientific article published in June 2005

Off-pump coronary artery bypass grafting does not preserve renal function better than on-pump coronary artery bypass grafting: results of a case-matched study.

scientific article published on 27 October 2011

Off-pump minimally invasive coronary artery bypass grafting using the bilateral internal thoracic arteries and the right gastroepiproic artery

scientific article published on 14 September 2015

Operative mortality with coronary artery bypass graft: where do we stand in 2015?

scientific article published on 08 September 2015

PET imaging of a collagen matrix reveals its effective injection and targeted retention in a mouse model of myocardial infarction.

scientific article published on 11 February 2015

Percutaneous mitral valve repair for chronic ischemic mitral regurgitation: a real-time three-dimensional echocardiographic study in an ovine model.

scientific article published on 25 April 2005

Perioperative deaths after mitral valve operations may be overestimated by contemporary risk models

scientific article published on 24 June 2014

Postoperative lipid-lowering therapy and bioprosthesis structural valve deterioration: justification for a randomised trial?

scientific article published on 11 August 2009

Preclinical evaluation of biopolymer-delivered circulating angiogenic cells in a swine model of hibernating myocardium

scientific article

Predictive factors, management, and clinical outcomes of coronary obstruction following transcatheter aortic valve implantation: insights from a large multicenter registry.

scientific article

Predictors and impact of myocardial injury after transcatheter aortic valve replacement: a multicenter registry.

scientific article published on November 2015

Preoperative anaemia is a risk factor for mortality and morbidity following aortic valve surgery.

scientific article published on 25 March 2013

Preparation and characterization of circulating angiogenic cells for tissue engineering applications

scientific article published on 01 January 2014

Prevention of ischemia-reperfusion injury in cardiac surgery: therapeutic strategies targeting signaling pathways

scientific article published on 02 December 2014

Prosthesis-patient mismatch after aortic valve replacement predominantly affects patients with preexisting left ventricular dysfunction: effect on survival, freedom from heart failure, and left ventricular mass regression.

scientific article published in May 2006

Prosthesis-patient mismatch is less frequent and more clinically indolent in patients operated for aortic insufficiency.

scientific article published on 26 March 2009

Radial artery graft treatment with phenoxybenzamine is clinically safe and may reduce perioperative myocardial injury

scientific article published on 01 February 2007

Regenerative therapies for improving myocardial perfusion in patients with cardiovascular disease: failure to meet expectations but optimism for the future.

scientific article

Repeat cardiac surgery in a Jehovah's Witness patient with thrombocytopenia

scientific article

Resection of right atrial tumor thrombi without circulatory arrest.

scientific article published in February 2001

Results of the Minimally Invasive Coronary Artery Bypass Grafting Angiographic Patency Study

scientific article

Secondary prevention after coronary artery bypass graft surgery: a scientific statement from the American Heart Association.

scientific article published on 9 February 2015

Should dual antiplatelet therapy be used in patients following coronary artery bypass surgery? A meta-analysis of randomized controlled trials

scientific article

Should we anticoagulate after bioprosthetic aortic valve replacement?

scientific article published on December 2013

Skeletonized internal thoracic artery harvest reduces pain and dysesthesia and improves sternal perfusion after coronary artery bypass surgery: a randomized, double-blind, within-patient comparison

scientific article published on 14 August 2006

Statin therapy and saphenous vein graft disease after coronary bypass surgery: analysis from the CASCADE randomized trial

scientific article published on 01 October 2011

Subannular prosthetic valve embolization complicating transapical transcatheter aortic valve implantation: management without sternotomy

scientific article

Successful pulmonary thrombectomy for malignant tumor thrombus after adrenal cancer resection

scientific article published on 27 September 2013

Successful surgical repair of ventricular double rupture

scientific article published on 01 November 2011

Surgery for chronic thromboembolic pulmonary hypertension--inclusive experience from a national referral center.

scientific article published on March 2007

Surgical approach to repair of ruptured chordae tendineae causing tricuspid regurgitation

scientific article published on 02 May 2008

Testosterone enhances cardiomyogenesis in stem cells and recruits the androgen receptor to the MEF2C and HCN4 genes.

scientific article published on 15 April 2013

The "hybrid flip-over" technique for anterior leaflet prolapse repair

scientific article published on 01 January 2007

The Learning Curve and Annual Procedure Volume Standards for Optimum Outcomes of Transcatheter Aortic Valve Replacement: Findings From an International Registry

scientific article published on 01 September 2018

The clinical application potential of extracellular matrix in cardiac tissue engineering.

scientific article published on 7 August 2015

The effect of encapsulation of cardiac stem cells within matrix-enriched hydrogel capsules on cell survival, post-ischemic cell retention and cardiac function

scientific article published on 04 October 2013

The future of regenerating the myocardium

scientific article published on November 1, 2010

The impact of patient co-morbidities on the regenerative capacity of cardiac explant-derived stem cells

scientific article published on 26 May 2016

The impact of patient-prosthesis mismatch on late outcomes after mitral valve replacement.

scientific article published on 27 April 2007

The impact of prosthesis-patient mismatch after aortic valve replacement varies according to age at operation.

scientific article published on 19 May 2014

The many challenges of interpreting recurrent moderate mitral regurgitation after MitraClip percutaneous mitral valve repair: What does it mean?

scientific article published on 29 October 2015

The role of integrin α2 in cell and matrix therapy that improves perfusion, viability and function of infarcted myocardium

scientific article published on 14 March 2014

Timing underpins the benefits associated with injectable collagen biomaterial therapy for the treatment of myocardial infarction

scientific article

Tissue engineering a small diameter vessel substitute: engineering constructs with select biomaterials and cells

scientific article published on 01 May 2012

Tissue-engineered injectable collagen-based matrices for improved cell delivery and vascularization of ischemic tissue using CD133+ progenitors expanded from the peripheral blood.

scientific article published in July 2006

Tracking stem cell therapy in the myocardium: applications of positron emission tomography.

scientific article published on January 2008

Transcatheter aortic-valve replacement: a cardiac surgeon and cardiologist team perspective.

scientific article published on March 2010

Transfemoral vs Non-transfemoral Access for Transcatheter Aortic Valve Implantation: A Systematic Review and Meta-analysis.

scientific article published on 30 April 2015

Twenty-year durability of the aortic Hancock II bioprosthesis in young patients: is it durable enough?

scientific article published on 07 February 2014

Use of bilateral internal thoracic artery during coronary artery bypass graft surgery in Canada: The bilateral internal thoracic artery survey

scientific article published on 18 February 2012

Valproic acid and bleeding: caution required

scientific article published on 01 February 2007

Vascular growth factors and angiogenesis in cardiac surgery.

scientific article

Vasomotor dysfunction after cardiac surgery.

scientific article

Very long-term survival implications of heart valve replacement with tissue versus mechanical prostheses in adults <60 years of age.

scientific article published in September 2007

Warfarin Treatment After Bioprosthetic Aortic Valve Replacement

scientific article published on March 27, 2013