List of works - Rebecca B Riggins

Acquisition of estrogen independence induces TOB1-related mechanisms supporting breast cancer cell proliferation

scientific article published on 13 July 2015

Alterations in Cell Motility, Proliferation, and Metabolism in Novel Models of Acquired Temozolomide Resistant Glioblastoma.

scientific article published on 8 May 2018

Antiestrogens, aromatase inhibitors, and apoptosis in breast cancer

scientific article

Antimitotic activity of DY131 and the estrogen-related receptor beta 2 (ERRβ2) splice variant in breast cancer

scientific article published on 30 May 2016

BCL2 and CASP8 regulation by NF-kappaB differentially affect mitochondrial function and cell fate in antiestrogen-sensitive and -resistant breast cancer cells.

scientific article

Breast cancer antiestrogen resistance-3 expression regulates breast cancer cell migration through promotion of p130Cas membrane localization and membrane ruffling

scientific article

Co-inhibition of BCL-W and BCL2 restores antiestrogen sensitivity through BECN1 and promotes an autophagy-associated necrosis

scientific article

Differential prioritization of therapies to subtypes of triple negative breast cancer using a systems medicine method

scientific article published on 9 October 2017

ERK/MAPK regulates ERRγ expression, transcriptional activity and receptor-mediated tamoxifen resistance in ER+ breast cancer

scientific article

ERRβ splice variants differentially regulate cell cycle progression.

scientific article

ERRγ target genes are poor prognostic factors in Tamoxifen-treated breast cancer

scientific article published on 15 May 2015

Endoplasmic reticulum stress, the unfolded protein response, and gene network modeling in antiestrogen resistant breast cancer

scientific article published on March 2011

Functions of the adapter protein Cas: signal convergence and the determination of cellular responses

scientific article

G-DOC: a systems medicine platform for personalized oncology

scientific article

Gene network signaling in hormone responsiveness modifies apoptosis and autophagy in breast cancer cells

scientific article published on March 2009

Human X-box binding protein-1 confers both estrogen independence and antiestrogen resistance in breast cancer cell lines.

scientific article

IFNgamma restores breast cancer sensitivity to fulvestrant by regulating STAT1, IFN regulatory factor 1, NF-kappaB, BCL2 family members, and signaling to caspase-dependent apoptosis

scientific article

Identification of condition-specific regulatory modules through multi-level motif and mRNA expression analysis.

scientific article

Identifying cancer biomarkers by network-constrained support vector machines

scientific article

Identifying protein interaction subnetworks by a bagging Markov random field-based method.

scientific article published on 17 November 2012

Integrated molecular analysis of Tamoxifen-resistant invasive lobular breast cancer cells identifies MAPK and GRM/mGluR signaling as therapeutic vulnerabilities

scientific article

Interferon regulatory factor-1 signaling regulates the switch between autophagy and apoptosis to determine breast cancer cell fate

scientific article

Motif-guided sparse decomposition of gene expression data for regulatory module identification

scientific article

Multilevel support vector regression analysis to identify condition-specific regulatory networks

scientific article

NF-κB signaling is required for XBP1 (unspliced and spliced)-mediated effects on antiestrogen responsiveness and cell fate decisions in breast cancer

scientific article

Nutritional modulation of the cell cycle and breast cancer.

scientific article

Orphan nuclear receptors in breast cancer pathogenesis and therapeutic response.

scientific article

Physical and functional interactions between Cas and c-Src induce tamoxifen resistance of breast cancer cells through pathways involving epidermal growth factor receptor and signal transducer and activator of transcription 5b.

scientific article

Reconstruction of transcriptional regulatory networks by stability-based network component analysis.

scientific article published on November 2013

Robust identification of transcriptional regulatory networks using a Gibbs sampler on outlier sum statistic

scientific article published in 2014

Synergistic promotion of c-Src activation and cell migration by Cas and AND-34/BCAR3.

scientific article

The A4396G polymorphism in interferon regulatory factor 1 is frequently expressed in breast cancer cell lines.

scientific article published on May 2007

The mitochondrial citrate carrier, SLC25A1, drives stemness and therapy resistance in non-small cell lung cancer.

scientific article published on 12 April 2018

The proapoptotic molecule BLID interacts with Bcl-XL and its downregulation in breast cancer correlates with poor disease-free and overall survival.

scientific article published on 16 April 2010

The role of X-box binding protein-1 in tumorigenicity.

scientific article published on June 2009

Trans-resveratrol boronic acid exhibits enhanced anti-proliferative activity on estrogen-dependent MCF-7 breast cancer cells

scientific article published on August 2012

interferon regulatory factor-1 mediates the proapoptotic but not cell cycle arrest effects of the steroidal antiestrogen ICI 182,780 (faslodex, fulvestrant).

scientific article published on June 2004

List of works by Rebecca B Riggins

Acquisition of estrogen independence induces TOB1-related mechanisms supporting breast cancer cell proliferation

Alterations in Cell Motility, Proliferation, and Metabolism in Novel Models of Acquired Temozolomide Resistant Glioblastoma.

Antiestrogens, aromatase inhibitors, and apoptosis in breast cancer

Antimitotic activity of DY131 and the estrogen-related receptor beta 2 (ERRβ2) splice variant in breast cancer

BCL2 and CASP8 regulation by NF-kappaB differentially affect mitochondrial function and cell fate in antiestrogen-sensitive and -resistant breast cancer cells.

Breast cancer antiestrogen resistance-3 expression regulates breast cancer cell migration through promotion of p130Cas membrane localization and membrane ruffling

Co-inhibition of BCL-W and BCL2 restores antiestrogen sensitivity through BECN1 and promotes an autophagy-associated necrosis

Differential prioritization of therapies to subtypes of triple negative breast cancer using a systems medicine method

ERK/MAPK regulates ERRγ expression, transcriptional activity and receptor-mediated tamoxifen resistance in ER+ breast cancer

ERRβ splice variants differentially regulate cell cycle progression.

ERRγ target genes are poor prognostic factors in Tamoxifen-treated breast cancer

Endoplasmic reticulum stress, the unfolded protein response, and gene network modeling in antiestrogen resistant breast cancer

Functions of the adapter protein Cas: signal convergence and the determination of cellular responses

G-DOC: a systems medicine platform for personalized oncology

Gene network signaling in hormone responsiveness modifies apoptosis and autophagy in breast cancer cells

Human X-box binding protein-1 confers both estrogen independence and antiestrogen resistance in breast cancer cell lines.

IFNgamma restores breast cancer sensitivity to fulvestrant by regulating STAT1, IFN regulatory factor 1, NF-kappaB, BCL2 family members, and signaling to caspase-dependent apoptosis

Identification of condition-specific regulatory modules through multi-level motif and mRNA expression analysis.

Identifying cancer biomarkers by network-constrained support vector machines

Identifying protein interaction subnetworks by a bagging Markov random field-based method.

Integrated molecular analysis of Tamoxifen-resistant invasive lobular breast cancer cells identifies MAPK and GRM/mGluR signaling as therapeutic vulnerabilities

Interferon regulatory factor-1 signaling regulates the switch between autophagy and apoptosis to determine breast cancer cell fate

Motif-guided sparse decomposition of gene expression data for regulatory module identification

Multilevel support vector regression analysis to identify condition-specific regulatory networks

NF-κB signaling is required for XBP1 (unspliced and spliced)-mediated effects on antiestrogen responsiveness and cell fate decisions in breast cancer

Nutritional modulation of the cell cycle and breast cancer.

Orphan nuclear receptors in breast cancer pathogenesis and therapeutic response.

Physical and functional interactions between Cas and c-Src induce tamoxifen resistance of breast cancer cells through pathways involving epidermal growth factor receptor and signal transducer and activator of transcription 5b.

Reconstruction of transcriptional regulatory networks by stability-based network component analysis.

Robust identification of transcriptional regulatory networks using a Gibbs sampler on outlier sum statistic

Synergistic promotion of c-Src activation and cell migration by Cas and AND-34/BCAR3.

The A4396G polymorphism in interferon regulatory factor 1 is frequently expressed in breast cancer cell lines.

The mitochondrial citrate carrier, SLC25A1, drives stemness and therapy resistance in non-small cell lung cancer.

The proapoptotic molecule BLID interacts with Bcl-XL and its downregulation in breast cancer correlates with poor disease-free and overall survival.

The role of X-box binding protein-1 in tumorigenicity.

Trans-resveratrol boronic acid exhibits enhanced anti-proliferative activity on estrogen-dependent MCF-7 breast cancer cells

interferon regulatory factor-1 mediates the proapoptotic but not cell cycle arrest effects of the steroidal antiestrogen ICI 182,780 (faslodex, fulvestrant).