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List of works by Helmut Segner

15N Metabolic test for the determination of phytotoxic effects of chemicals and contaminated environmental samples

17Beta-estradiol affects the response of complement components and survival of rainbow trout (Oncorhynchus mykiss) challenged by bacterial infection ⬇️

scientific article published on April 28, 2011

20 Years of fish immunotoxicology - what we know and where we are.

scientific article

A natural freshwater origin for two chlamydial species, Candidatus Piscichlamydia salmonis and Candidatus Clavochlamydia salmonicola, causing mixed infections in wild brown trout (Salmo trutta).

scientific article published on 19 December 2011

A role for multiple estrogen receptors in immune regulation of common carp

scientific article published on 7 April 2016

A survey on the expression of IGF-I in the early developing bony fish with special emphasis on the tilapia, Oreochromis niloticus

scientific article

ABC transporters and xenobiotic defense systems in early life stages of rainbow trout (Oncorhynchus mykiss).

scientific article published on 02 March 2016

ABC transporters in gills of rainbow trout (Oncorhynchus mykiss)

scientific article published on 12 June 2020

Advances in the Multibiomarker Approach for Risk Assessment in Aquatic Ecosystems

Alterations of tissue glutathione levels and metallothionein mRNA in rainbow trout during single and combined exposure to cadmium and zinc

scientific article published in March 2002

An International Perspective on the Tools and Concepts for Effluent Toxicity Assessments in the Context of Animal Alternatives: Reduction in Vertebrate Use

article

An environmentally relevant concentration of estrogen induces arrest of male gonad development in zebrafish, Danio rerio

scientific article published in May 2005

Analysis of protein expression in zebrafish during gonad differentiation by targeted proteomics

scientific article published on 19 August 2013

Antimicrobial activity and mechanisms of multiple antimicrobial peptides isolated from rockfish Sebastiscus marmoratus

scientific article published on 23 August 2019

Aromatase in zebrafish: a potential target for endocrine disrupting chemicals

scientific article published on 7 April 2006

Aromatase modulation alters gonadal differentiation in developing zebrafish (Danio rerio).

scientific article published in April 2004

Aryl Hydrocarbon Receptor Signaling Is Functional in Immune Cells of Rainbow Trout (Oncorhynchus mykiss)

scientific article published on 31 August 2020

Assessment of estrogenic exposure in brown trout (Salmo trutta) in a Swiss midland river: integrated analysis of passive samplers, wild and caged fish, and vitellogenin mRNA and protein

scientific article published in August 2006

Attenuated virulence of an Aeromonas salmonicida subsp. salmonicida type III secretion mutant in a rainbow trout model

scientific article published in June 2005

Benzo(a)pyrene Metabolism and EROD and GST Biotransformation Activity in the Liver of Red- and White-Blooded Antarctic Fish

scientific article

Beta-naphthoflavone alters normal plasma levels of vitellogenin, 17 beta-estradiol and luteinizing hormone in sea bass broodstock

scientific article published in May 2004

Candidatus Syngnamydia venezia, a novel member of the phylum Chlamydiae from the broad nosed pipefish, Syngnathus typhle

scientific article

Characterization of the estrogenicity of Swiss midland rivers using a recombinant yeast bioassay and plasma vitellogenin concentrations in feral male brown trout

scientific article

Comet assay with the fish cell line rainbow trout gonad-2 for in vitro genotoxicity testing of xenobiotics and surface waters

scientific article published on August 2005

Comparative Cytotoxicity Study of Silver Nanoparticles (AgNPs) in a Variety of Rainbow Trout Cell Lines (RTL-W1, RTH-149, RTG-2) and Primary Hepatocytes

scientific article published on 20 May 2015

Cytochrome P4501A induction in brown trout exposed to small streams of an urbanised area: results of a five-year-study

scientific article published on July 2005

Cytotoxicity assays with fish cells as an alternative to the acute lethality test with fish

scientific article

Cytotoxicity of metals toward rainbow trout R1 cell line

scholarly article by Helmut Segner et al published November 1994 in Environmental toxicology and water quality

Detection and quantification of Flavobacterium psychrophilum in water and fish tissue samples by quantitative real time PCR

scientific article

Determination of Metabolic Stability Using Cryopreserved Hepatocytes from Rainbow Trout (Oncorhynchus mykiss).

scientific article

Developmental oestrogen exposure differentially modulates IGF-I and TNF-α expression levels in immune organs of Yersinia ruckeri-challenged young adult rainbow trout (Oncorhynchus mykiss).

scientific article published on 27 May 2014

Differential expression of IGF-I mRNA and peptide in the male and female gonad during early development of a bony fish, the tilapia Oreochromis niloticus

scientific article published on 18 January 2006

Do fish get wasted? Assessing the influence of effluents on parasitic infection of wild fish

scientific article published on 13 November 2018

Does hepatotoxicity interfere with endocrine activity in zebrafish (Danio rerio)?

scientific article published on 14 August 2019

Ecological Relevance of Key Toxicants in Aquatic Systems

article

Endocrine disrupting compounds: Can they target the immune system of fish? ⬇️

scientific article published on June 17, 2011

Environmentally relevant concentrations of 17alpha-ethinylestradiol (EE2) interfere with the growth hormone (GH)/insulin-like growth factor (IGF)-I system in developing bony fish

scientific article published on 27 July 2008

Establishing Causality between Pollution and Effects at Different Levels of Biological Organization: The VALIMAR Project

article by Rita Triebskorn et al published January 2003 in Human and Ecological Risk Assessment: An International Journal

Estrogen Modulates Hepatic Gene Expression and Survival of Rainbow Trout Infected with Pathogenic Bacteria Yersinia ruckeri ⬇️

scientific article published on July 24, 2012

Estrogenic Endocrine Disruption in Switzerland: Assessment of Fish Exposure and Effects

article

Ethinylestradiol differentially interferes with IGF-I in liver and extrahepatic sites during development of male and female bony fish

scientific article published in December 2007

Expert opinion on toxicity profiling--report from a NORMAN expert group meeting

scientific article

Expression of zebra fish aromatase cyp19a and cyp19b genes in response to the ligands of estrogen receptor and aryl hydrocarbon receptor

scientific article published on 18 January 2007

Feed contamination with zearalenone promotes growth but affects the immune system of rainbow trout

article

Fluorescent In Situ hybridization: a new tool for the direct identification and detection of F. psychrophilum

scientific article

Future water quality monitoring--adapting tools to deal with mixtures of pollutants in water resource management

scientific article published on 31 January 2015

Hepatocytes as in vitro test system to investigate metabolite patterns of pesticides in farmed rainbow trout and common carp: Comparison between in vivo and in vitro and across species

scientific article published on 13 May 2016

Human and ecological risk assessment of a crop protection chemical: a case study with the azole fungicide epoxiconazole

scientific article

INDUCTION OF CYP1A BY THE N-IMIDAZOLE DERIVATIVE, 1-BENZYLIMIDAZOLE

Identification of candidate genes and physiological pathways involved in gonad deformation in whitefish (Coregonus spp.) from Lake Thun, Switzerland

scientific article

Immune-Specific Expression and Estrogenic Regulation of the Four Estrogen Receptor Isoforms in Female Rainbow Trout (Oncorhynchus mykiss).

scientific article

Immunotoxic effects of environmental toxicants in fish — how to assess them? ⬇️

scientific article published on August 31, 2012

Impact of environmental estrogens on Yfish considering the diversity of estrogen signaling

scientific article published on 11 June 2013

In response: The evidence--What actions are needed to effectively transfer from science to policy? An academic perspective

scientific article published in June 2015

In vitro methodologies in ecotoxicological hazard assessment: the case of bioaccumulation testing for fish

scientific article

In vitro or not in vitro: a short journey through a long history

scientific article published on 26 June 2018

In-vitroscreening of the antiestrogenic activity of chemicals

Increasing Scientific Confidence in Adverse Outcome Pathways: Application of Tailored Bradford-Hill Considerations for Evaluating Weight of Evidence

scientific article published on 8 April 2015

Induction of CYP1A by the N-imidazole derivative, 1-benzylimidazole

scientific article published in April 2003

Induction of cytochrome P4501A (CYP1A) by clotrimazole, a non-planar aromatic compound. Computational studies on structural features of clotrimazole and related imidazole derivatives

scientific article published in December 2004

Integrated testing strategy (ITS) for bioaccumulation assessment under REACH.

scientific article published on 4 May 2014

Interference of endocrine disrupting chemicals with aromatase CYP19 expression or activity, and consequences for reproduction of teleost fish

scientific article published on 21 March 2007

Intersex occurrence in rainbow trout (Oncorhynchus mykiss) male fry chronically exposed to ethynylestradiol

scientific article

Intra- and interlaboratory reliability of a cryopreserved trout hepatocyte assay for the prediction of chemical bioaccumulation potential

scientific article published on 2 July 2014

Investigating the role of free-ranging wild boar (Sus scrofa) in the re-emergence of enzootic pneumonia in domestic pig herds: a pathological, prevalence and risk-factor study

scientific article

Let us empower the WFD to prevent risks of chemical pollution in European rivers and lakes

scientific article published on 7 August 2019

Life-stage-dependent sensitivity of zebrafish (Danio rerio) to estrogen exposure

scientific article published in October 2004

Linear Alkylbenzene Sulfonates and Intermediate Products from their Degradation are not Estrogenic

article published in 1999

Linking Ah receptor mediated effects of sediments and impacts on fish to key pollutants in the Yangtze Three Gorges Reservoir, China - A comprehensive perspective

scientific article published on 20 August 2015

MODELKEY. Models for assessing and forecasting the impact of environmental key pollutants on freshwater and marine ecosystems and biodiversity

scientific article published in September 2005

Molecular epidemiology of Flavobacterium psychrophilum from Swiss fish farms

scientific article published on September 2013

Monitoring pollution in river Mureş, Romania, Part III: biochemical effect markers in fish and integrative reflection

scientific article published on 7 September 2006

Morphological alterations in the liver of yellow perch (Perca flavescens) from a biological mercury hotspot

scientific article

Moving beyond a descriptive aquatic toxicology: The value of biological process and trait information ⬇️

scientific article published on June 28, 2011

Multivariate mode-of-action analysis of acute toxicity of phenols

article

Nutritional Metabolic Bone Disease in Juvenile Veiled Chameleons (Chamaeleo calyptratus) and Its Prevention ⬇️

scientific article published on September 29, 2010

Optimizing the aquatic toxicity assessment under REACH through an integrated testing strategy (ITS).

scientific article

Pathogenic infection confounds induction of the estrogenic biomarker vitellogenin in rainbow trout

scientific article published on 23 August 2012

Persistent organic pollutants in red- and white-blooded High-Antarctic notothenioid fish from the remote Weddell Sea.

scientific article

Persistent organic pollutants in tissues of the white-blooded Antarctic fish Champsocephalus gunnari and Chaenocephalus aceratus

scientific article

Prochloraz causes irreversible masculinization of zebrafish (Danio rerio).

scientific article published on 28 August 2014

Protein and Lipid Binding Parameters in Rainbow Trout (Oncorhynchus mykiss) Blood and Liver Fractions to Extrapolate from anin VitroMetabolic Degradation Assay toin VivoBioaccumulation Potential of Hydrophobic Organic Chemicals ⬇️

scientific article published on June 8, 2011

Screening and testing for endocrine disruption in fish-biomarkers as "signposts," not "traffic lights," in risk assessment

scientific article published on April 2006

Sensitivity of brown trout reproduction to long-term estrogenic exposure

scientific article

Sex-specific immunomodulatory action of the environmentalestrogen 17α-ethynylestradiol alongside with reproductive impairment in fish

scientific article published on 31 July 2018

Strengthen the European collaborative environmental research to meet European policy goals for achieving a sustainable, non-toxic environment

scientific article published on 30 September 2019

Surface marker-defined head kidney granulocytes and B lymphocytes of rainbow trout express benzo[a]pyrene-inducible cytochrome P4501A protein

scientific article

The 2015 Annual Meeting of SETAC German Language Branch in Zurich (7-10 September, 2015): Ecotoxicology and environmental chemistry-from research to application

scientific article

The SOLUTIONS project: challenges and responses for present and future emerging pollutants in land and water resources management

scientific article

The emergence of epitheliocystis in the upper Rhone region: evidence for Chlamydiae in wild and farmed salmonid populations

scientific article published on 22 January 2016

The immunomodulatory role of the hypothalamus-pituitary-gonad axis: Proximate mechanism for reproduction-immune trade offs?

scientific article

The potential of mechanism-based bioanalytical tools in ecotoxicological exposure and effect assessment

scientific article

The state of in vitro science for use in bioaccumulation assessments for fish

scientific article published on January 2009

The teleostean liver as an immunological organ: Intrahepatic immune cells (IHICs) in healthy and benzo[a]pyrene challenged rainbow trout (Oncorhynchus mykiss).

scientific article published on 6 April 2014

The use of mechanisms and modes of toxic action in integrated testing strategies: the report and recommendations of a workshop held as part of the European Union OSIRIS Integrated Project

scientific article published in November 2009

The zebrafish, brain-specific, aromatase cyp19a2 is neither expressed nor distributed in a sexually dimorphic manner during sexual differentiation

scientific article published in November 2007

Thyroid Hormone Disruptors Interfere with Molecular Pathways of Eye Development and Function in Zebrafish ⬇️

article

Tissue-specific metabolism of benzo[a]pyrene in rainbow trout (Oncorhynchus mykiss): a comparison between the liver and immune organs.

scientific article

Toward sustainable environmental quality: Priority research questions for Europe

scholarly article

Towards science-based sediment quality standards-Effects of field-collected sediments in rainbow trout (Oncorhynchus mykiss).

scientific article

Use ofIn VitroAbsorption, Distribution, Metabolism, and Excretion (ADME) Data in Bioaccumulation Assessments for Fish

scientific article published in 2007

Variability of in vivo fish acute toxicity data

scientific article

Vitellogenin synthesis in primary cultures of fish liver cells as endpoint for in vitro screening of the (anti)estrogenic activity of chemical substances

scientific article published on September 2006

What constitutes a model organism in ecotoxicology?

scientific article published on 3 December 2015

Who needs the hotspot? The effect of temperature on the fish host immune response to Tetracapsuloides bryosalmonae the causative agent of proliferative kidney disease

scientific article published on 23 February 2017

Wirkungsforschung in der Chemischen Ökotoxikologie

scientific article published in 1994

Zebrafish (Danio rerio) as a model organism for investigating endocrine disruption

scientific article published on 14 October 2008

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