List of works - Jacek Plewka

A bacteriophage mimic of the bacterial nucleoid-associated protein Fis

scientific article published on 24 March 2020

A computationally designed β-amino acid-containing miniprotein

scientific article published in 2021

A fragment-based approach identifies an allosteric pocket that impacts malate dehydrogenase activity

scientific article published on 10 August 2021

Antibody Binding Heterogeneity of Protein A Resins

scientific article published on 20 May 2019

Antibody adsorption in protein-A affinity chromatography - in situ measurement of nanoscale structure by small-angle X-ray scattering

scientific article published on 16 October 2018

CA-170 - A Potent Small-Molecule PD-L1 Inhibitor or Not?

scientific article published on 01 August 2019

Competition NMR for Detection of Hit/Lead Inhibitors of Protein-Protein Interactions

scientific article published on 01 July 2020

Design, Synthesis, and Biological Evaluation of Imidazopyridines as PD-1/PD-L1 Antagonists

scientific article published on 28 April 2021

Despite the odds: formation of the SARS-CoV-2 methylation complex

scientific article published on 26 January 2022

Di-Bromo-based small-molecule inhibitors of the PD-1/PD-L1 immune checkpoint

scientific article published on 16 September 2020

Human and mouse PD-L1: similar molecular structure, but different druggability profiles

scientific article published on 22 January 2021

Macrocyclic Peptide Inhibitor of PD‐1/PD‐L1 Immune Checkpoint

scientific article published on 18 November 2020

Multicomponent Peptide Stapling as a Diversity-Driven Tool for the Development of Inhibitors of Protein-Protein Interactions

scientific article published on 06 February 2020

Novel Gene Mutation in One of Dizygotic Twins Causing Profound Changes of Receptor Structure

scientific article published in 2022

PD-L1 Inhibitors: Different Classes, Activities, and Mechanisms of Action

scientific article published on 30 October 2021

Pseudanabaena galeata CCNP1313—Biological Activity and Peptides Production

scientific article published on 6 May 2022

Refolding of lid subdomain of SARS-CoV-2 nsp14 upon nsp10 interaction releases exonuclease activity

scientific article published on 18 February 2022

Refolding of lid subdomain of SARS-CoV-2 nsp14 upon nsp10 interaction releases exonuclease activity

scientific article published on 20 May 2022

TRIM5α SPRY/coiled-coil interactions optimize avid retroviral capsid recognition

scientific article published on 17 October 2017

Terphenyl-Based Small-Molecule Inhibitors of Programmed Cell Death-1/Programmed Death-Ligand 1 Protein-Protein Interaction

scientific article published on 12 August 2021

The pearl necklace model in protein A chromatography: Molecular mechanisms at the resin interface

scientific article published on 25 October 2018

Viscoelasticity and structure of blood clots generated in-vitro by rheometry: A comparison between human, horse, rat, and camel

scientific article published on 01 January 2018

List of works by Jacek Plewka

A bacteriophage mimic of the bacterial nucleoid-associated protein Fis

A computationally designed β-amino acid-containing miniprotein

A fragment-based approach identifies an allosteric pocket that impacts malate dehydrogenase activity

Antibody Binding Heterogeneity of Protein A Resins

Antibody adsorption in protein-A affinity chromatography - in situ measurement of nanoscale structure by small-angle X-ray scattering

CA-170 - A Potent Small-Molecule PD-L1 Inhibitor or Not?

Competition NMR for Detection of Hit/Lead Inhibitors of Protein-Protein Interactions

Design, Synthesis, and Biological Evaluation of Imidazopyridines as PD-1/PD-L1 Antagonists

Despite the odds: formation of the SARS-CoV-2 methylation complex

Di-Bromo-based small-molecule inhibitors of the PD-1/PD-L1 immune checkpoint

Human and mouse PD-L1: similar molecular structure, but different druggability profiles

Macrocyclic Peptide Inhibitor of PD‐1/PD‐L1 Immune Checkpoint

Multicomponent Peptide Stapling as a Diversity-Driven Tool for the Development of Inhibitors of Protein-Protein Interactions

Novel Gene Mutation in One of Dizygotic Twins Causing Profound Changes of Receptor Structure

PD-L1 Inhibitors: Different Classes, Activities, and Mechanisms of Action

Pseudanabaena galeata CCNP1313—Biological Activity and Peptides Production

Refolding of lid subdomain of SARS-CoV-2 nsp14 upon nsp10 interaction releases exonuclease activity

Refolding of lid subdomain of SARS-CoV-2 nsp14 upon nsp10 interaction releases exonuclease activity

TRIM5α SPRY/coiled-coil interactions optimize avid retroviral capsid recognition

Terphenyl-Based Small-Molecule Inhibitors of Programmed Cell Death-1/Programmed Death-Ligand 1 Protein-Protein Interaction

The pearl necklace model in protein A chromatography: Molecular mechanisms at the resin interface

Viscoelasticity and structure of blood clots generated in-vitro by rheometry: A comparison between human, horse, rat, and camel