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List of works by Michael G Kharas

A 1536-well fluorescence polarization assay to screen for modulators of the MUSASHI family of RNA-binding proteins.

scientific article

Altered Nuclear Export Signal Recognition as a Driver of Oncogenesis

scientific article published on 08 July 2019

Author Correction: ChromaFold predicts the 3D contact map from single-cell chromatin accessibility ⬇️

scientific article published on 15 January 2025

ChromaFold predicts the 3D contact map from single-cell chromatin accessibility ⬇️

scientific article published in November 2024

Csnk1a1 inhibition has p53-dependent therapeutic efficacy in acute myeloid leukemia.

scientific article

From Hen House to Bedside: Tracing Hanafusa's Legacy from Avian Leukemia Viruses to SRC to ABL and Beyond

scientific article

HyperTRIBE uncovers increased MUSASHI-2 RNA binding activity and differential regulation in leukemic stem cells

scientific article published on 24 April 2020

MSI2 is required for maintaining activated myelodysplastic syndrome stem cells

scientific article published on 22 February 2016

Modulation of the IGF1R-MTOR pathway attenuates motor neuron toxicity of human ALS SOD1<sup>G93A</sup> astrocytes

scientific article published on 22 March 2021

Msi RNA-binding proteins control reserve intestinal stem cell quiescence.

scientific article published on 31 October 2016

Musashi-2 controls cell fate, lineage bias, and TGF-β signaling in HSCs

scientific article published on 06 January 2014

Musashi-2 regulates normal hematopoiesis and promotes aggressive myeloid leukemia

scientific article

PI3K inhibition results in enhanced estrogen receptor function and dependence in hormone receptor-positive breast cancer

scientific article published on April 2015

Peptidomimetic blockade of MYB in acute myeloid leukemia

scientific article published on 9 January 2018

RNA-binding proteins Musashi and tau soluble aggregates initiate nuclear dysfunction

scientific article published on 27 August 2020

Real-time quantitative analysis of metabolic flux in live cells using a hyperpolarized micromagnetic resonance spectrometer

scientific article

Small-molecule targeting of MUSASHI RNA-binding activity in acute myeloid leukemia.

scientific article

The Lin28/let-7 axis regulates glucose metabolism

scientific article

The N6-methyladenosine (m6A)-forming enzyme METTL3 controls myeloid differentiation of normal hematopoietic and leukemia cells. ⬇️

scientific article published on 18 September 2017

Therapeutic efficacy of an Fc-enhanced TCR-like antibody to the intracellular WT1 oncoprotein

scientific article

Transformation of the intestinal epithelium by the MSI2 RNA-binding protein.

scientific article

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