List of works - Jon E Hawkinson

7-Methylation of Chenodeoxycholic Acid Derivatives Yields a Substantial Increase in TGR5 Receptor Potency

scientific article published on 03 July 2019

Automated Live-Cell Imaging of Synapses in Rat and Human Neuronal Cultures

scientific article published on 17 October 2019

Cooperativity Between Orthosteric Inhibitors and Allosteric Inhibitor 8-Anilino-1-Naphthalene Sulfonic Acid (ANS) in Cyclin-Dependent Kinase 2

scientific article published on 20 May 2020

Design, Synthesis, and Characterization of a Fluorescence Polarization Pan-BET Bromodomain Probe

scientific article published on 31 October 2018

Design, Synthesis, and in Vitro and in Vivo Evaluation of Ouabain Analogues as Potent and Selective Na,K-ATPase α4 Isoform Inhibitors for Male Contraception

scientific article published in January 2018

Development of WEE2 kinase inhibitors as novel non-hormonal female contraceptives that target meiosis†

scientific article published on 12 June 2020

FBNTI, a DOR-Selective Antagonist That Allosterically Activates MOR within a MOR-DOR Heteromer

scientific article published on 20 September 2020

From HTS to Phase I: the Institute for Therapeutics Discovery and Development at the University of Minnesota

scientific article published in March 2014

Human Adenine Nucleotide Translocase (ANT) Modulators Identified by High-Throughput Screening of Transgenic Yeast

scientific article published on 8 January 2016

Pharmacological, pharmacokinetic, and primate analgesic efficacy profile of the novel bradykinin B1 Receptor antagonist ELN441958.

scientific article published on 30 April 2007

Potent Pyrimidine and Pyrrolopyrimidine Inhibitors of Testis-Specific Serine/Threonine Kinase 2 (TSSK2).

scientific article published on 26 September 2017

Probing the S2' Subsite of the Anthrax Toxin Lethal Factor Using Novel N-Alkylated Hydroxamates

scientific article

Quantification of Adverse Events Associated with Functional MRI Scanning and with Real-Time fMRI-Based Training ⬇️

scientific article published on September 1, 2012

Quantifying the Selectivity of Protein-Protein and Small Molecule Interactions with Fluorinated Tandem Bromodomain Reader Proteins

scientific article published on 03 November 2020

Recombinant production of enzymatically active male contraceptive drug target hTSSK2 - Localization of the TSKS domain phosphorylated by TSSK2

scientific article

Reduction of protein kinase A-mediated phosphorylation of ATXN1-S776 in Purkinje cells delays onset of Ataxia in a SCA1 mouse model.

scientific article

Structure-Activity Studies of N-Butyl-1-deoxynojirimycin (NB-DNJ) Analogues: Discovery of Potent and Selective Aminocyclopentitol Inhibitors of GBA1 and GBA2.

scientific article published on 3 October 2017

Synthesis and SAR of novel di- and trisubstituted 1,4-dihydroquinoxaline-2,3-diones related to licostinel (Acea 1021) as NMDA/glycine site antagonists

scientific article published in April 2003

The Fungal Sexual Pheromone Sirenin Activates the Human CatSper Channel Complex

scientific article published on 16 December 2015

The anti-parasitic agent suramin and several of its analogues are inhibitors of the DNA binding protein Mcm10

scientific article published on 14 August 2019

List of works by Jon E Hawkinson

7-Methylation of Chenodeoxycholic Acid Derivatives Yields a Substantial Increase in TGR5 Receptor Potency

Automated Live-Cell Imaging of Synapses in Rat and Human Neuronal Cultures

Cooperativity Between Orthosteric Inhibitors and Allosteric Inhibitor 8-Anilino-1-Naphthalene Sulfonic Acid (ANS) in Cyclin-Dependent Kinase 2

Design, Synthesis, and Characterization of a Fluorescence Polarization Pan-BET Bromodomain Probe

Design, Synthesis, and in Vitro and in Vivo Evaluation of Ouabain Analogues as Potent and Selective Na,K-ATPase α4 Isoform Inhibitors for Male Contraception

Development of WEE2 kinase inhibitors as novel non-hormonal female contraceptives that target meiosis†

FBNTI, a DOR-Selective Antagonist That Allosterically Activates MOR within a MOR-DOR Heteromer

From HTS to Phase I: the Institute for Therapeutics Discovery and Development at the University of Minnesota

Human Adenine Nucleotide Translocase (ANT) Modulators Identified by High-Throughput Screening of Transgenic Yeast

Pharmacological, pharmacokinetic, and primate analgesic efficacy profile of the novel bradykinin B1 Receptor antagonist ELN441958.

Potent Pyrimidine and Pyrrolopyrimidine Inhibitors of Testis-Specific Serine/Threonine Kinase 2 (TSSK2).

Probing the S2' Subsite of the Anthrax Toxin Lethal Factor Using Novel N-Alkylated Hydroxamates

Quantification of Adverse Events Associated with Functional MRI Scanning and with Real-Time fMRI-Based Training ⬇️

Quantifying the Selectivity of Protein-Protein and Small Molecule Interactions with Fluorinated Tandem Bromodomain Reader Proteins

Recombinant production of enzymatically active male contraceptive drug target hTSSK2 - Localization of the TSKS domain phosphorylated by TSSK2

Reduction of protein kinase A-mediated phosphorylation of ATXN1-S776 in Purkinje cells delays onset of Ataxia in a SCA1 mouse model.

Structure-Activity Studies of N-Butyl-1-deoxynojirimycin (NB-DNJ) Analogues: Discovery of Potent and Selective Aminocyclopentitol Inhibitors of GBA1 and GBA2.

Synthesis and SAR of novel di- and trisubstituted 1,4-dihydroquinoxaline-2,3-diones related to licostinel (Acea 1021) as NMDA/glycine site antagonists

The Fungal Sexual Pheromone Sirenin Activates the Human CatSper Channel Complex

The anti-parasitic agent suramin and several of its analogues are inhibitors of the DNA binding protein Mcm10