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List of works by Martin Witzenrath

"Atypische" bakterielle Pneumonie - Tipps zu Diagnostik und Therapie : Infektiologie

scientific article published on 01 September 2020

"Management of Community-Acquired Pneumonia in Immunocompromised Adults: A Consensus Statement Regarding Initial Strategies"

scientific article published on 16 June 2020

25-hydroxvitamin D3 promotes the long-term effect of specific immunotherapy in a murine allergy model

scientific article published on 20 June 2014

A Biomathematical Model of Pneumococcal Lung Infection and Antibiotic Treatment in Mice

scientific article

A SARS-CoV-2 neutralizing antibody protects from lung pathology in a COVID-19 hamster model

scientific article published on 16 August 2020

A Semi-Synthetic Glycoconjugate Vaccine Candidate for Carbapenem-Resistant Klebsiella pneumoniae

A Semi-synthetic Oligosaccharide Conjugate Vaccine Candidate Confers Protection against Streptococcus pneumoniae Serotype 3 Infection.

scientific article published on 2 November 2016

A Streptococcus pneumoniae Type 2 Oligosaccharide Glycoconjugate Elicits Opsonic Antibodies and Is Protective in an Animal Model of Invasive Pneumococcal Disease

scientific article published on 25 September 2017

A Therapeutic Non-self-reactive SARS-CoV-2 Antibody Protects from Lung Pathology in a COVID-19 Hamster Model

scientific article published on 23 September 2020

A biomathematical model of immune response and barrier function in mice with pneumococcal lung infection

scientific article published on 03 December 2020

A semi-synthetic glycoconjugate vaccine candidate for carbapenem-resistant Klebsiella pneumoniae

scientific article published on 16 August 2017

A semisynthetic Streptococcus pneumoniae serotype 8 glycoconjugate vaccine.

scientific article published on March 2017

Acute Moraxella catarrhalis Airway Infection of Chronically Smoke-Exposed Mice Increases Mechanisms of Emphysema Development: A Pilot Study

scientific article published on 11 December 2018

Adrenomedullin attenuates ventilator-induced lung injury in mice ⬇️

scientific article published on October 22, 2010

Adrenomedullin reduces endothelial hyperpermeability

scientific article

Angiopoietin-2 sensitizes endothelial cells to TNF-alpha and has a crucial role in the induction of inflammation

scientific article published on 5 February 2006

Anti-C5a antibody IFX-1 (vilobelimab) treatment versus best supportive care for patients with severe COVID-19 (PANAMO): an exploratory, open-label, phase 2 randomised controlled trial

scientific article published on 28 September 2020

Antibiotic treatment-induced secondary IgA deficiency enhances susceptibility to Pseudomonas aeruginosa pneumonia

scholarly article by Oliver H Robak et al published 1 August 2018 in Journal of Clinical Investigation

Antihistone Properties of C1 Esterase Inhibitor Protect against Lung Injury

scientific article published on 22 December 2016

Arterial hypertension in a murine model of sleep apnea: role of NADPH oxidase 2.

scientific article published on February 2014

Autoantibodies to angiotensin and endothelin receptors in systemic sclerosis induce cellular and systemic events associated with disease pathogenesis

scientific article published on 28 January 2014

COVID-19 severity correlates with airway epithelium-immune cell interactions identified by single-cell analysis

scientific article published on 26 June 2020

Cardiovascular sequelae of pneumonia

scientific article published on 01 May 2019

Cell-specific interleukin-15 and interleukin-15 receptor subunit expression and regulation in pneumococcal pneumonia--comparison to chlamydial lung infection.

scientific article published on May 2007

Chronic liver disease negatively affects outcome in hospitalised patients with community-acquired pneumonia

scientific article published on 06 April 2020

Classical transient receptor potential channel 1 in hypoxia-induced pulmonary hypertension

scientific article

Clinical classifiers of COVID-19 infection from novel ultra-high-throughput proteomics

scientific article published on 03 May 2020

Cross-talk between the airway epithelium and activated immune cells defines severity in COVID-19

scientific article published on 05 May 2020

Cystathionine γ-Lyase-Produced Hydrogen Sulfide Controls Endothelial NO Bioavailability and Blood Pressure

scientific article published on 30 April 2018

Delay in antibiotic therapy results in fatal disease outcome in murine pneumococcal pneumonia

scientific article published in November 2018

Delayed viral clearance and exacerbated airway hyperinflammation in hypertensive COVID-19 patients ⬇️

journal article from 'medRxiv' published in 2020

Delivery of the endolysin Cpl-1 by inhalation rescues mice with fatal pneumococcal pneumonia

scientific article published on 30 April 2013

Detection of allergen-induced airway hyperresponsiveness in isolated mouse lungs.

scientific article published on 14 April 2006

Development of an Efficacious, Semisynthetic Glycoconjugate Vaccine Candidate against Streptococcus pneumoniae Serotype 1.

scientific article published on 14 March 2018

Digital Image Analyses on Whole Lung Slides in Mouse Models of Acute Pneumonia

scientific article published on 23 January 2018

Dissection of a type I interferon pathway in controlling bacterial intracellular infection in mice

scientific article published on 24 August 2011

Dynamics of cytokines, immune cell counts and disease severity in patients with community-acquired pneumonia - Unravelling potential causal relationships

scientific article published on 03 September 2020

Dynamics of pulmonary endothelial barrier function in acute inflammation: mechanisms and therapeutic perspectives

scientific article published on 06 March 2014

Effects of dimethylarginine dimethylaminohydrolase-1 overexpression on the response of the pulmonary vasculature to hypoxia.

scientific article published on September 2013

Endoscopic Lung Volume Reduction: Can Endobronchial Valves Be Safely Removed?

scientific article published on 20 March 2020

Endothelial adhesion molecules and multiple organ failure in patients with severe sepsis.

scientific article published in October 2016

Endothelial progenitor cells for acute respiratory distress syndrome treatment: support your local sheriff!

scientific article published in June 2014

High endocan levels are associated with the need for mechanical ventilation among patients with severe sepsis

scientific article published on 5 July 2017

Histone acetylation and flagellin are essential for Legionella pneumophila-induced cytokine expression.

scientific article

Hypoxic pulmonary vasoconstriction requires connexin 40-mediated endothelial signal conduction.

scientific article

Hypoxic vascular response and ventilation/perfusion matching in end-stage COPD may depend on p22phox.

scientific article published on 20 July 2017

IFNs Modify the Proteome of Legionella-Containing Vacuoles and Restrict Infection Via IRG1-Derived Itaconic Acid

scientific article

Immunomodulation by fish-oil containing lipid emulsions in murine acute respiratory distress syndrome

scientific article published on 29 April 2014

Immunomodulation by lipid emulsions in pulmonary inflammation: a randomized controlled trial

scientific article

Immunostimulation with macrophage-activating lipopeptide-2 increased survival in murine pneumonia

scientific article published on 17 October 2008

Improving vaccines against Streptococcus pneumoniae using synthetic glycans

scientific article published on 07 December 2018

Increasing the inspiratory time and I:E ratio during mechanical ventilation aggravates ventilator-induced lung injury in mice

scientific article

Indwelling pleural catheters for malignancy-associated pleural effusion: report on a single centre's ten years of experience ⬇️

scientific article published on 02 December 2019

Indwelling pleural catheters for non-malignant pleural effusions: report on a single centre's 10 years of experience

scientific article published on 01 January 2020

Infectious Causes of Granulomatous Lung Diseases

scientific article published on 5 January 2017

Intermedin stabilized endothelial barrier function and attenuated ventilator-induced lung injury in mice

scientific article

Intracellular bacteria differentially regulated endothelial cytokine release by MAPK-dependent histone modification

scientific article published in September 2005

Juvenile megaesophagus in PKCα-deficient mice is associated with an increase in the segment of the distal esophagus lined by smooth muscle cells

scientific article published on 4 May 2014

Listeria monocytogenes-infected human peripheral blood mononuclear cells produce IL-1beta, depending on listeriolysin O and NLRP3.

scientific article

Local ablative treatment for synchronous single organ oligometastatic lung cancer-A propensity score analysis of 180 patients

scientific article published on 25 September 2018

Macrolide combination therapy for patients hospitalised with community-acquired pneumonia? An individualised approach supported by machine learning

scientific article published on 12 December 2019

Markov State Modelling of Disease Courses and Mortality Risks of Patients with Community-Acquired Pneumonia

scientific article published on 05 February 2020

Maternal asthma is associated with persistent changes in allergic offspring antibody glycosylation

scientific article published on 28 January 2020

Mechanical ventilation drives pneumococcal pneumonia into lung injury and sepsis in mice: protection by adrenomedullin

scientific article

Mediastinal emphysema after long-distance flight with ketoacidosis and underlying diabetes mellitus type 1

scientific article published on 05 April 2019

Miniaturized bronchoscopy enables unilateral investigation, application, and sampling in mice.

scientific article published on December 2014

Moraxella catarrhalis induces an immune response in the murine lung that is independent of human CEACAM5 expression and long-term smoke exposure

scientific article published on 5 June 2015

Murine CLCA5 is uniquely expressed in distinct niches of airway epithelial cells

scientific article

N-3 vs. n-6 fatty acids differentially influence calcium signalling and adhesion of inflammatory activated monocytes: impact of lipid rafts.

scientific article

NF-κB2/p100 deficiency impairs immune responses to T-cell-independent type 2 antigens.

scientific article

NLRP3 protects alveolar barrier integrity by an inflammasome-independent increase of epithelial cell adherence.

scientific article published on August 2016

Neutralizing Complement C5a Protects Mice with Pneumococcal Pulmonary Sepsis

scientific article published on 01 April 2020

No SARS-CoV-2 detection in the German CAPNETZ cohort of community acquired pneumonia before COVID-19 peak in March 2020

scientific article published on 03 July 2020

Nucleotide oligomerization domain 1 ligation suppressed murine allergen-specific T-cell proliferation and airway hyperresponsiveness

scientific article published on May 2014

On Top of the Alveolar Epithelium: Surfactant and the Glycocalyx

scientific article published on 27 April 2020

Optimising experimental research in respiratory diseases: an ERS statement.

scientific article

PKCα Deficiency in Mice Is Associated with Pulmonary Vascular Hyperresponsiveness to Thromboxane A2 and Increased Thromboxane Receptor Expression

scientific article

Pemetrexed-Based Chemotherapy Is Inferior to Pemetrexed-Free Regimens in Thyroid Transcription Factor 1 (TTF-1)-Negative, EGFR/ALK-Negative Lung Adenocarcinoma: A Propensity Score Matched Pairs Analysis

scientific article published on 22 May 2020

Perturbation of endothelial junction proteins by Staphylococcus aureus alpha-toxin: inhibition of endothelial gap formation by adrenomedullin

scientific article published on 5 April 2006

Phage capsid nanoparticles with defined ligand arrangement block influenza virus entry

scientific article published on 30 March 2020

Phosphodiesterase 2 inhibition diminished acute lung injury in murine pneumococcal pneumonia

scientific article

Plasma mediators in patients with severe COVID-19 cause lung endothelial barrier failure

scientific article published on 05 November 2020

Pneumococcal conjugate serotype distribution and predominating role of serotype 3 in German adults with community-acquired pneumonia

scientific article published on 21 November 2019

Pneumolysin induced mitochondrial dysfunction leads to release of mitochondrial DNA.

scientific article

Pneumolysin induces platelet destruction, not platelet activation, which can be prevented by immunoglobulin preparations in vitro

scientific article published on 01 December 2020

Pneumonia in the face of COVID-19

scientific article published on 30 September 2020

Presence of SARS-CoV-2 reactive T cells in COVID-19 patients and healthy donors

scientific article published on 22 April 2020

Prognostic and Pathogenic Role of Angiopoietin-1 and -2 in Pneumonia

scientific article published on 15 February 2018

Proteasome β5i Subunit Deficiency Affects Opsonin Synthesis and Aggravates Pneumococcal Pneumonia

scientific article

Pulmonary immunostimulation with MALP-2 in influenza virus-infected mice increases survival after pneumococcal superinfection

scientific article

RNAi-mediated suppression of constitutive pulmonary gene expression by small interfering RNA in mice

scientific article published in April 2010

Rate and Predictors of Bacteremia in Afebrile Community-Acquired Pneumonia

scientific article published on 26 October 2019

Resolvin E1 and its precursor 18R-HEPE restore mitochondrial function in inflammation

scientific article published on 12 June 2018

Rho-kinase and contractile apparatus proteins in murine airway hyperresponsiveness.

scientific article published on 22 April 2008

Role of Ryanodine Type 2 Receptors in Elementary Ca Signaling in Arteries and Vascular Adaptive Responses

article

Role of Transient Receptor Potential Vanilloid 4 in Neutrophil Activation and Acute Lung Injury

scientific article published on 29 July 2015

Role of local pulmonary IFN-gamma expression in murine allergic airway inflammation

scientific article published on 16 March 2006

Role of platelet-activating factor in pneumolysin-induced acute lung injury

scientific article published in July 2007

Role of pneumolysin for the development of acute lung injury in pneumococcal pneumonia.

scientific article published in July 2006

Role of sphingosine kinase 1 in allergen-induced pulmonary vascular remodeling and hyperresponsiveness

scientific article published on 8 August 2009

SARS-CoV-2-reactive T cells in healthy donors and patients with COVID-19

scientific article published on 29 July 2020

Schistosomiasis in European Travelers and Migrants: Analysis of 14 Years TropNet Surveillance Data

scientific article published on 30 May 2017

Semisynthetic glycoconjugate vaccine candidate against Streptococcus pneumoniae serotype 5.

scientific article published on 2 October 2017

Sequential organ failure assessment score is an excellent operationalization of disease severity of adult patients with hospitalized community acquired pneumonia - results from the prospective observational PROGRESS study

scientific article published on 04 April 2019

Severe COVID-19 Is Marked by a Dysregulated Myeloid Cell Compartment

scientific article published on 05 August 2020

Severe Pneumococcal Pneumonia Causes Acute Cardiac Toxicity and Subsequent Cardiac Remodeling.

scientific article published on 14 June 2017

Simvastatin Attenuates Ventilator-induced Lung Injury In Mice

scholarly article published May 2010

Simvastatin attenuates ventilator-induced lung injury in mice

scientific article

Simvastatin reduces Chlamydophila pneumoniae-mediated histone modifications and gene expression in cultured human endothelial cells

scientific article published on 28 February 2008

Small interfering RNA against transcription factor STAT6 inhibits allergic airway inflammation and hyperreactivity in mice

scientific article

Spectrum of pathogen- and model-specific histopathologies in mouse models of acute pneumonia

scientific article

Sphingosine Kinase 1 Regulates Inflammation and Contributes to Acute Lung Injury in Pneumococcal Pneumonia via the Sphingosine-1-Phosphate Receptor 2.

scientific article published on 2 January 2018

Sphingosine-1-phospate receptor 4 (S1P₄) deficiency profoundly affects dendritic cell function and TH17-cell differentiation in a murine model

scientific article published on 08 August 2011

Streptococcus pneumoniae induced p38 MAPK- and NF-kappaB-dependent COX-2 expression in human lung epithelium

scientific article

Streptococcus pneumoniae stimulates a STING- and IFN regulatory factor 3-dependent type I IFN production in macrophages, which regulates RANTES production in macrophages, cocultured alveolar epithelial cells, and mouse lungs

scientific article published on 12 December 2011

Structural and functional prevention of hypoxia-induced pulmonary hypertension by individualized exercise training in mice

scientific article published on 4 April 2014

Studying the pathophysiology of coronavirus disease 2019 - a protocol for the Berlin prospective COVID-19 patient cohort (Pa- COVID-19)

scientific article published on 11 May 2020

Studying the pathophysiology of coronavirus disease 2019: a protocol for the Berlin prospective COVID-19 patient cohort (Pa-COVID-19)

scientific article published on 13 June 2020

Surfactant protein A mediates pulmonary clearance of Staphylococcus aureus

scientific article published on 5 August 2014

Systemic use of the endolysin Cpl-1 rescues mice with fatal pneumococcal pneumonia.

scientific article published in February 2009

TLR2- and nucleotide-binding oligomerization domain 2-dependent Krüppel-like factor 2 expression downregulates NF-kappa B-related gene expression.

scientific article

TLR9- and Src-dependent expression of Krueppel-like factor 4 controls interleukin-10 expression in pneumonia

scientific article

The C-type lectin receptor Mincle binds to Streptococcus pneumoniae but plays a limited role in the anti-pneumococcal innate immune response

scientific article

The Glycemic Gap and 90-Day Mortality in Community-acquired Pneumonia. A Prospective Cohort Study

scientific article published on 01 December 2019

The NLRP3 Inflammasome Is Differentially Activated by Pneumolysin Variants and Contributes to Host Defense in Pneumococcal Pneumonia

scientific article published on 06 June 2011

The Sphingosine-1 Phosphate receptor agonist FTY720 dose dependently affected endothelial integrity in vitro and aggravated ventilator-induced lung injury in mice

scientific article

The cGAS/STING pathway detects Streptococcus pneumoniae but appears dispensable for anti-pneumococcal defense in mice and humans.

scientific article published on 20 December 2017

The common HAQ STING variant impairs cGAS-dependent antibacterial responses and is associated with susceptibility to Legionnaires' disease in humans.

scientific article published on 3 January 2018

Time for tailored antimicrobials: adapted bacteriophages in the ICU.

scientific article published in June 2015

Towards Inhaled Phage Therapy in Western Europe

scientific article published on 23 March 2019

Tumor necrosis factor-alpha-dependent expression of phosphodiesterase 2: role in endothelial hyperpermeability

scientific article

Ultra-High-Throughput Clinical Proteomics Reveals Classifiers of COVID-19 Infection

scientific article published on 02 June 2020

Undiagnosed Diabetes Mellitus in Community-Acquired Pneumonia: A Prospective Cohort Study

scholarly article by Andreas Vestergaard Jensen et al published 29 November 2017 in Clinical Infectious Diseases

Vascular Receptor Autoantibodies in Pulmonary Arterial Hypertension Associated with Systemic Sclerosis

scientific article published on 01 October 2014

Vasculotide reduces pulmonary hyperpermeability in experimental pneumococcal pneumonia.

scientific article published on 13 November 2017

Ventilator-induced lung injury is aggravated by antibiotic mediated microbiota depletion in mice

scientific article published on 29 October 2018

[Community-acquired pneumonia in adults]

scientific article published on 19 March 2020

[Rare pulmonary infections]

scientific article published on 31 August 2020

[Unexpected increase in extravascular lung water after acute lung injury]

scientific article published on 13 August 2020

cIAP-1 controls innate immunity to C. pneumoniae pulmonary infection

scientific article (publication date: 2009)

mCLCA3 modulates IL-17 and CXCL-1 induction and leukocyte recruitment in murine Staphylococcus aureus pneumonia

scientific article

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