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List of works by Sophie Van Linthout

A P19 and P19CL6 cell-based complementary approach to determine paracrine effects in cardiac tissue engineering

scientific article published on 21 August 2014

A Toolbox of Potential Immune-Related Therapies for Inflammatory Cardiomyopathy

scientific article published on 21 May 2020

Akt/protein kinase B and endothelial nitric oxide synthase mediate muscular neovascularization induced by tissue kallikrein gene transfer

scientific article published on 13 September 2004

Apolipoprotein A-I gene transfer exerts immunomodulatory effects and reduces vascular inflammation and fibrosis in ob/ob mice.

scientific article published on 02 August 2016

CX3CR1 knockout aggravates Coxsackievirus B3-induced myocarditis

scientific article published on 11 August 2017

Cardiac (myo)fibroblasts modulate the migration of monocyte subsets

scientific article published on 3 April 2018

Cardiac Extracellular Vesicles (EVs) Released in the Presence or Absence of Inflammatory Cues Support Angiogenesis in Different Manners ⬇️

scientific article published on 17 December 2019

Cardiac cell therapies: the next generation

scientific article published on 14 October 2010

Cardiac cell therapy: anno 2011

scientific article published on 01 October 2011

Cardiac contractility modulation signals improve exercise intolerance and maladaptive regulation of cardiac key proteins for systolic and diastolic function in HFpEF.

scientific article published on 27 October 2015

Cardiac contractility modulation: mechanisms of action in heart failure with reduced ejection fraction and beyond

scientific article published on 28 November 2018

Cardiac effects of HDL and its components on diabetic cardiomyopathy.

scientific article published on June 2012

Cardiac function and remodeling is attenuated in transgenic rats expressing the human kallikrein-1 gene after myocardial infarction

scientific article published on 7 September 2006

Cardiac migration of endogenous mesenchymal stromal cells in patients with inflammatory cardiomyopathy

scientific article

Cardioprotective and anti-inflammatory effects of interleukin converting enzyme inhibition in experimental diabetic cardiomyopathy

scientific article published in May 2007

Cardioprotective mechanisms of the kallikrein-kinin system in diabetic cardiopathy.

scientific article

Circadian rhythms in ischaemic heart disease: key aspects for preclinical and translational research: position paper of the ESC working group on cellular biology of the heart

scientific article published in 2021

Coronary microvascular dysfunction in heart failure with preserved ejection fraction - adding new pieces to the jigsaw puzzle

scientific article published on 07 January 2020

Coronary microvascular dysfunction in hypertrophy and heart failure

scientific article published on 01 March 2020

Critical role of scavenger receptor-BI-expressing bone marrow-derived endothelial progenitor cells in the attenuation of allograft vasculopathy after human apo A-I transfer

scientific article published on 29 September 2008

Crosstalk between fibroblasts and inflammatory cells

scientific article published on 11 April 2014

Down-regulation of endothelial TLR4 signalling after apo A-I gene transfer contributes to improved survival in an experimental model of lipopolysaccharide-induced inflammation

scientific article published on 24 October 2010

ESC Working Group on Cellular Biology of the Heart: position paper for Cardiovascular Research: tissue engineering strategies combined with cell therapies for cardiac repair in ischaemic heart disease and heart failure

scientific article published on 01 March 2019

Early Treatment of Coxsackievirus B3-Infected Animals With Soluble Coxsackievirus-Adenovirus Receptor Inhibits Development of Chronic Coxsackievirus B3 Cardiomyopathy

scientific article published on 13 November 2019

Effect of promoters and enhancers on expression, transgene DNA persistence, and hepatotoxicity after adenoviral gene transfer of human apolipoprotein A-I

article

Elimination of innate immune responses and liver inflammation by PEGylation of adenoviral vectors and methylprednisolone

scientific article

Empagliflozin directly improves diastolic function in human heart failure

scientific article published on 17 October 2018

Empagliflozin improves endothelial and cardiomyocyte function in human heart failure with preserved ejection fraction via reduced pro-inflammatory-oxidative pathways and protein kinase Gα oxidation

scientific article published on 12 May 2020

Endomyocardial biopsy derived adherent proliferating cells - a potential cell source for cardiac tissue engineering

scientific article published in February 2010

Enhanced Cardiomyocyte Function in Hypertensive Rats With Diastolic Dysfunction and Human Heart Failure Patients After Acute Treatment With Soluble Guanylyl Cyclase (sGC) Activator

scientific article published on 25 May 2020

Epigenetic modulation of vascular diseases: Assessing the evidence and exploring the opportunities

scientific article published on 13 March 2018

Extracellular vesicles from regenerative human cardiac cells act as potent immune modulators by priming monocytes

scientific article published on 27 May 2019

Heart Failure with Preserved Ejection Fraction and Future Pharmacological Strategies: a Glance in the Crystal Ball

scientific article

High-density lipoprotein at the interface of type 2 diabetes mellitus and cardiovascular disorders.

scientific article published on May 2010

High-density lipoprotein-raising strategies: update 2010.

scientific article published on May 2010

High-density lipoproteins reduce endothelial-to-mesenchymal transition

scientific article published on 18 June 2015

High-density lipoproteins reduce palmitate-induced cardiomyocyte apoptosis in an AMPK-dependent manner

scientific article published on 8 September 2015

Human ApoA-I transfer attenuates transplant arteriosclerosis via enhanced incorporation of bone marrow-derived endothelial progenitor cells

scientific article published on 6 December 2007

Human Endomyocardial Biopsy Specimen-Derived Stromal Cells Modulate Angiotensin II-Induced Cardiac Remodeling.

scientific article published on 26 July 2016

Human apolipoprotein A-I gene transfer reduces the development of experimental diabetic cardiomyopathy

scientific article published on 10 March 2008

Human cardiac-derived adherent proliferating cells reduce murine acute Coxsackievirus B3-induced myocarditis

scientific article

Immune attributes of cardiac-derived adherent proliferating (CAP) cells in cardiac therapy

scientific article

Immunomodulation by adoptive regulatory T-cell transfer improves Coxsackievirus B3-induced myocarditis

scientific article published on 04 June 2018

Immunomodulatory effects of mesenchymal stromal cells revisited in the context of inflammatory cardiomyopathy

scientific article published on 19 June 2013

Immunosuppression in inflammatory cardiomyopathy and parvovirus B19 persistence

scientific article published on 02 September 2019

Impact of HDL on adipose tissue metabolism and adiponectin expression

scientific article

Impaired Endothelial Regeneration Through Human Parvovirus B19-Infected Circulating Angiogenic Cells in Patients With Cardiomyopathy

scientific article

Inflammation - Cause or Consequence of Heart Failure or Both?

scientific article

Innate and adaptive immunity in atherosclerosis

scientific article published on 22 April 2018

Interferon beta modulates endothelial damage in patients with cardiac persistence of human parvovirus b19 infection.

scientific article

Interleukin-6 receptor inhibition modulates the immune reaction and restores titin phosphorylation in experimental myocarditis

scientific article published on 25 October 2014

Investigating a biomarker-driven approach to target collagen turnover in diabetic heart failure with preserved ejection fraction patients. Effect of torasemide vs. furosemide on serum C-terminal propeptide of procollagen type I (DROP-PIP trial).

scientific article published on 11 September 2017

LXR agonism improves TNF-α-induced endothelial dysfunction in the absence of its cholesterol-modulating effects.

scientific article published on 26 October 2013

Lack in treatment options for virus-induced inflammatory cardiomyopathy: can iPS-derived cardiomyocytes close the gap?

scientific article published in August 2014

Lost in markers? Time for phenomics and phenomapping in dilated cardiomyopathy

scientific article published on 19 January 2017

MALDI-IMS As A Tool to Determine The myocardial Response to Syndecan-2-selected Mesenchymal Stromal Cell Application in An Experimental Model of Diabetic Cardiomyopathy

scientific article published on 17 October 2020

Management of Myocarditis-Related Cardiomyopathy in Adults

scientific article published on 01 May 2019

Mechanical Unloading by Fulminant Myocarditis: LV-IMPELLA, ECMELLA, BI-PELLA, and PROPELLA Concepts

scientific article published on 06 August 2018

Mesenchymal Stromal Cells Modulate Monocytes Trafficking in Coxsackievirus B3-Induced Myocarditis

scientific article published on 3 January 2017

Mesenchymal stromal cells inhibit NLRP3 inflammasome activation in a model of Coxsackievirus B3-induced inflammatory cardiomyopathy

scientific article published on 12 February 2018

Mode-of-action of the PROPELLA concept in fulminant myocarditis

scientific article published on 01 July 2019

Modulation of the acute defence reaction by eplerenone prevents cardiac disease progression in viral myocarditis

scientific article published on 14 July 2020

Myocarditis and inflammatory cardiomyopathy: current evidence and future directions

scientific article published on 12 October 2020

NOD2 (Nucleotide-Binding Oligomerization Domain 2) Is a Major Pathogenic Mediator of Coxsackievirus B3-Induced Myocarditis

scientific article published on September 2017

Nerve growth factor promotes cardiac repair following myocardial infarction

scientific article

New insights in (inter)cellular mechanisms by heart failure with preserved ejection fraction

scientific article published on December 2014

Nitric oxide-releasing aspirin derivative, NCX 4016, promotes reparative angiogenesis and prevents apoptosis and oxidative stress in a mouse model of peripheral ischemia

scientific article (publication date: November 2004)

Opioid-Induced Immunomodulation: Consequences for the Experimental Coxsackievirus B3-Induced Myocarditis Model

scientific article published on 13 October 2020

Pathogenic Role of the Damage-Associated Molecular Patterns S100A8 and S100A9 in Coxsackievirus B3-Induced Myocarditis

scientific article published in November 2017

Placenta-Derived Adherent Stromal Cells Improve Diabetes Mellitus-Associated Left Ventricular Diastolic Performance ⬇️

scientific article published on 10 October 2017

Reduced MMP-2 activity contributes to cardiac fibrosis in experimental diabetic cardiomyopathy.

scientific article

Regional and global protective effects of tissue kallikrein gene delivery to the peri-infarct myocardium

scientific article

Reversible transition from a hypertrophic to a dilated cardiomyopathy.

scientific article published on 09 December 2015

Role of heart rate reduction in the prevention of experimental heart failure: comparison between If-channel blockade and β-receptor blockade.

scientific article published on 9 April 2012

SARS-CoV2-related myocarditis-like syndroms: Shakespeare´s question: What´s in a name?

scientific article published on 19 May 2020

Staurosporine-induced differentiation of the RGC-5 cell line leads to apoptosis and cell death at the lowest differentiating concentration

scientific article published on 6 January 2012

Stimulating pro-reparative immune responses to prevent adverse cardiac remodelling: Consensus Document from the joint 2019 meeting of the ESC Working Groups of Cellular Biology of the heart and Myocardial Function

scientific article published on 12 May 2020

Systems biology identifies cytosolic PLA2 as a target in vascular calcification treatment.

scientific article published on 16 May 2019

Targeting CD20+ B-lymphocytes in inflammatory dilated cardiomyopathy with rituximab improves clinical course: a case series

scientific article published on 01 September 2019

Telbivudine in chronic lymphocytic myocarditis and human parvovirus B19 transcriptional activity

The Quest for Antiinflammatory and Immunomodulatory Strategies in Heart Failure

scientific article published on 28 October 2019

The atrial appendage as a suitable source to generate cardiac-derived adherent proliferating cells for regenerative cell-based therapies.

scientific article published on 28 July 2017

The two faces of high-density lipoprotein

scientific article published in May 2010

Therapeutic potential of HDL in cardioprotection and tissue repair

scientific article

Tumor necrosis factor-alpha antagonism protects from myocardial inflammation and fibrosis in experimental diabetic cardiomyopathy

scientific article

Type-2 diabetic Lepr(db/db) mice show a defective microvascular phenotype under basal conditions and an impaired response to angiogenesis gene therapy in the setting of limb ischemia

scientific article

Vascular-protective effects of high-density lipoprotein include the downregulation of the angiotensin II type 1 receptor

scientific article published on 9 March 2009

Viral myocarditis: a prime example for endomyocardial biopsy-guided diagnosis and therapy

scientific article published on 9 March 2018

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