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List of works by Thorsten Trimbuch

A Trio of Active Zone Proteins Comprised of RIM-BPs, RIMs, and Munc13s Governs Neurotransmitter Release

scientific article published on 01 August 2020

A vicious cycle involving release of heat shock protein 60 from injured cells and activation of toll-like receptor 4 mediates neurodegeneration in the CNS.

scientific article

An unconventional role for miRNA: let-7 activates Toll-like receptor 7 and causes neurodegeneration.

scientific article published in June 2012

Autaptic cultures of human induced neurons as a versatile platform for studying synaptic function and neuronal morphology

article

BDNF Expression in Cortical GABAergic Interneurons

scientific article published on 25 February 2020

Clathrin regenerates synaptic vesicles from endosomes.

scientific article

Clathrin/AP-2 mediate synaptic vesicle reformation from endosome-like vacuoles but are not essential for membrane retrieval at central synapses.

scientific article

Complexin Suppresses Spontaneous Exocytosis by Capturing the Membrane-Proximal Regions of VAMP2 and SNAP25

scientific article published on 01 July 2020

Dendritic compartment and neuronal output mode determine pathway-specific long-term potentiation in the piriform cortex

scientific article published in October 2009

Differential pH Dynamics in Synaptic Vesicles From Intact Glutamatergic and GABAergic Synapses

scientific article published on 03 December 2018

Disentangling the roles of RIM and Munc13 in synaptic vesicle localization and neurotransmission

scientific article published on 02 November 2020

Distinct Functions of Syntaxin-1 in Neuronal Maintenance, Synaptic Vesicle Docking, and Fusion in Mouse Neurons.

scientific article published on July 2016

Distinct Localization of SNAP47 Protein in GABAergic and Glutamatergic Neurons in the Mouse and the Rat Hippocampus.

scientific article

Epilepsy-causing STX1B mutations translate altered protein functions into distinct phenotypes in mouse neurons

scientific article published on 23 June 2020

Functional synergy between the Munc13 C-terminal C1 and C2 domains

scientific article published on 23 May 2016

Heterodimerization of Munc13 C2A domain with RIM regulates synaptic vesicle docking and priming

scientific article

Human endogenous retrovirus HERV-K(HML-2) RNA causes neurodegeneration through Toll-like receptors

scientific article published on 09 April 2020

Investigation of synapse formation and function in a glutamatergic-GABAergic two-neuron microcircuit

scientific article published on 01 January 2014

Layer 6b Is Driven by Intracortical Long-Range Projection Neurons

scientific article published on 01 March 2020

Light-Activated ROS Production Induces Synaptic Autophagy

scientific article published on 17 January 2019

Loss of MeCP2 disrupts cell autonomous and autocrine BDNF signaling in mouse glutamatergic neurons

scientific article published on 26 October 2016

Loss of a mammalian circular RNA locus causes miRNA deregulation and affects brain function

scientific article published on 10 August 2017

Mechanistic insights into neurotransmitter release and presynaptic plasticity from the crystal structure of Munc13-1 C1C2BMUN.

scientific article published on 08 February 2017

Membrane bridging by Munc13-1 is crucial for neurotransmitter release

scientific article published on 28 February 2019

NOMA-GAP/ARHGAP33 regulates synapse development and autistic-like behavior in the mouse.

scientific article published on 14 April 2015

ORP/Osh mediate cross-talk between ER-plasma membrane contact site components and plasma membrane SNAREs

scientific article published on 30 July 2020

Parkin contributes to synaptic vesicle autophagy in Bassoon-deficient mice

scientific article published on 04 May 2020

Precise Somatotopic Thalamocortical Axon Guidance Depends on LPA-Mediated PRG-2/Radixin Signaling.

scientific article published on 13 September 2016

RIM-binding protein 2 regulates release probability by fine-tuning calcium channel localization at murine hippocampal synapses.

scientific article published on 26 September 2016

Re-examining how complexin inhibits neurotransmitter release

scientific article

Role of the transmembrane potential in the membrane proton leak.

scientific article

Should I stop or should I go? The role of complexin in neurotransmitter release.

scientific article

Synaptic PRG-1 Modulates Excitatory Transmission via Lipid Phosphate-Mediated Signaling

article

Synaptic PRG-1 modulates excitatory transmission via lipid phosphate-mediated signaling.

scientific article

Synaptobrevin 1 mediates vesicle priming and evoked release in a subpopulation of hippocampal neurons.

scientific article

Synaptojanin and Endophilin Mediate Neck Formation during Ultrafast Endocytosis

scientific article published on 01 June 2018

Synaptotagmin-1 drives synchronous Ca2+-triggered fusion by C2B-domain-mediated synaptic-vesicle-membrane attachment.

scientific article published on 11 December 2017

The Axonal Membrane Protein PRG2 Inhibits PTEN and Directs Growth to Branches

scientific article published on 01 November 2019

The RGS gene loco is essential for male reproductive system differentiation in Drosophila melanogaster

scientific article

Titration of Syntaxin1 in mammalian synapses reveals multiple roles in vesicle docking, priming, and release probability

scientific journal article

Ultrafast Recycling of Synaptic Vesicles

VGLUT2 EXPRESSION IN DOPAMINE NEURONS CONTRIBUTES TO POST-LESIONAL STRIATAL REINNERVATION

scientific article published on 14 September 2020

Vesicular glutamate transporter expression level affects synaptic vesicle release probability at hippocampal synapses in culture.

scientific article published in August 2014