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List of works by Norbert Suttorp

42-year-old woman with progressive dyspnea, lower limb swelling and skin lesions ⬇️

scientific article published on April 10, 2012

A case of multiple brain abscesses due to Streptococcus constellatus

scientific article published in February 2002

A haemorrhagic fever from the Côte d'Ivoire

scientific article published on November 1999

A permissive role for tumor necrosis factor in vascular endothelial growth factor-induced vascular permeability.

scientific article

A phase II study of weekly docetaxel-cisplatin as first-line treatment for advanced non-small cell lung cancer

scientific article

A severe case of leptospirosis acquired during an iron man contest.

scientific article published in February 2001

Activation of the pulmonary arachidonic acid system and its consequences for hemodynamics and fluid balance

scientific article published on January 1987

Acute fascioliasis with multiple liver abscesses

scientific article published in January 2000

Adenosine diphosphate-ribosylation of G-actin by botulinum C2 toxin increases endothelial permeability in vitro

scientific article published on May 1991

Adhesion of Moraxella catarrhalis to human bronchial epithelium characterized by a novel fluorescence-based assay

scientific article

Adrenomedullin attenuates ventilator-induced lung injury in mice ⬇️

scientific article published on October 22, 2010

Adrenomedullin reduces Staphylococcus aureus alpha-toxin-induced rat ileum microcirculatory damage

scientific article published in April 2005

Adrenomedullin reduces endothelial hyperpermeability

scientific article

Adrenomedullin reduces vascular hyperpermeability and improves survival in rat septic shock

scientific article published on 22 February 2007

Adrenomedullin treatment abolishes ileal mucosal hypoperfusion induced by Staphylococcus aureus alpha-toxin--an intravital microscopic study on an isolated rat ileum

scientific article published in December 2005

Allergic lung inflammation induces pulmonary vascular hyperresponsiveness

scientific article published on 29 March 2006

Antioxidant defense mechanisms of endothelial cells: glutathione redox cycle versus catalase

scientific article published on 01 November 1986

Ascending cellulitis after an insect bite

scientific article published in March 2001

Assessment of oxygenation and comorbidities improves outcome prediction in patients with community-acquired pneumonia with a low CRB-65 score

scientific article published on 13 February 2015

Avoiding invasive mechanical ventilation by extracorporeal carbon dioxide removal in patients failing noninvasive ventilation

scientific article

Bacterial exotoxins and endothelial permeability for water and albumin in vitro

scientific article

Bartonella henselae induces NF-kappaB-dependent upregulation of adhesion molecules in cultured human endothelial cells: possible role of outer membrane proteins as pathogenic factors

scientific article published on August 2001

Beta-PIX and Rac1 GTPase mediate trafficking and negative regulation of NOD2.

scientific article

Brain metastases of lung cancer

scientific article

CAPNETZ-community-acquired pneumonia competence network

scientific article published on 01 August 2004

CAPNet--network of competence for community acquired pneumonia: structures and aims

scientific article published in January 2003

CFTR and sphingolipids mediate hypoxic pulmonary vasoconstriction

scientific article

CRB-65 predicts death from community-acquired pneumonia

scientific article published in July 2006

Communicable diseases prioritized for surveillance and epidemiological research: results of a standardized prioritization procedure in Germany, 2011.

scientific article

Community-acquired pneumonia through Enterobacteriaceae and Pseudomonas aeruginosa: Diagnosis, incidence and predictors

scientific article published on 13 August 2009

Comparative transcriptional profiling of the lung reveals shared and distinct features of Streptococcus pneumoniae and influenza A virus infection.

scientific article published on 8 December 2006

Competence network "community acquired pneumonia" (CAPNETZ). A first interim report

scientific article published in April 2004

Complement complex C5b-8 induces PGI2 formation in cultured endothelial cells

scientific article published on 01 July 1987

Decreased Bactericidal Function and Impaired Respiratory Burst in Lung Macrophages after Sustained in vitro Hyperoxia ⬇️

scientific article published on 01 September 1983

Deregulation of the CEACAM expression pattern causes undifferentiated cell growth in human lung adenocarcinoma cells

scientific article

Development and evaluation of an implementation strategy for the German guideline on community-acquired pneumonia

scientific article

Differences in cell activation by Chlamydophila pneumoniae and Chlamydia trachomatis infection in human endothelial cells

scientific article

Differences in clinical manifestations of imported versus autochthonous leptospirosis in Austria and Germany

scientific article

Differential antiviral response of endothelial cells after infection with pathogenic and nonpathogenic hantaviruses

scientific article

Differential regulation of Moraxella catarrhalis-induced interleukin-8 response by protein kinase C isoforms.

scientific article published on 9 January 2008

Dissection of a type I interferon pathway in controlling bacterial intracellular infection in mice

scientific article published on 24 August 2011

Docetaxel/gemcitabine or cisplatin/gemcitabine followed by docetaxel in the first-line treatment of patients with metastatic non-small cell lung cancer (NSCLC): results of a multicentre randomized phase II trial

scientific article published on 10 October 2006

Domestic cholera in Germany associated with fresh fish imported from Nigeria

scientific article published on 7 November 2002

Early-stage elephantiasis in bancroftian filariasis

scientific article published in November 2001

Effectiveness of twice-weekly pyrimethamine-sulfadoxine as primary prophylaxis of Pneumocystis carinii pneumonia and toxoplasmic encephalitis in patients with advanced HIV infection

scientific article

Effects of Escherichia coli hemolysin on endothelial cell function

scientific article

Effects of bacterial exo- and endotoxins on endothelial arachidonate metabolism

scientific article published in January 1989

Effects of bacterial toxins and calcium-ionophores on endothelial permeability in vitro

scientific article published on 01 January 1989

Endotoxin alters arachidonate metabolism in pulmonary endothelial cells

scientific article published in September 1987

Erlotinib in patients with advanced non-small-cell lung cancer: impact of dose reductions and a novel surrogate marker

scientific article

Escherichia coli hemolysin and Staphylococcus aureas alpha-toxin potently induce neutrophil adhesion to cultured human endothelial cells.

scientific article

Escherichia coli hemolysin causes thromboxane-mediated hypertension and vascular leakage in rabbit lungs

scientific article

Escherichia coli hemolysin is a potent inductor of phosphoinositide hydrolysis and related metabolic responses in human neutrophils

scientific article published on November 1991

Essential role of mitochondrial antiviral signaling, IFN regulatory factor (IRF)3, and IRF7 in Chlamydophila pneumoniae-mediated IFN-beta response and control of bacterial replication in human endothelial cells

scientific article published on 12 February 2010

Extra- and intracellular innate immune recognition in endothelial cells.

scientific article published in August 2007

Genetic Factors of the Disease Course after Sepsis: A Genome-Wide Study for 28Day Mortality

scientific article published on 14 September 2016

Glucosylation of small GTP-binding Rho proteins disrupts endothelial barrier function

scientific article published on 01 January 1997

Gnathostomiasis without eosinophilia led to a 5-year delay in diagnosis.

scientific article published in May 2003

Histone acetylation and flagellin are essential for Legionella pneumophila-induced cytokine expression.

scientific article

How deadly is seasonal influenza-associated pneumonia? The German Competence Network for Community-Acquired Pneumonia

article

Human endothelial cell activation and mediator release in response to the bacterial exotoxins Escherichia coli hemolysin and staphylococcal alpha-toxin.

scientific article published on August 1997

Human neutrophil elastase increases permeability of cultured pulmonary endothelial cell monolayers

scientific article published on 01 December 1993

Hydrogen Peroxide-Induced Increase in Lung Endothelial and Epithelial Permeability-Effect of Adenylate Cyclase Stimulation and Phosphodiesterase Inhibition

scientific article published on 01 July 1995

Hyperpermeability of pulmonary endothelial monolayer: protective role of phosphodiesterase isoenzymes 3 and 4.

scientific article

IFNbeta induction by influenza A virus is mediated by RIG-I which is regulated by the viral NS1 protein

scientific article published on 28 November 2006

IFNbeta responses induced by intracellular bacteria or cytosolic DNA in different human cells do not require ZBP1 (DLM-1/DAI).

scientific article published on 2 September 2008

IFNs Modify the Proteome of Legionella-Containing Vacuoles and Restrict Infection Via IRG1-Derived Itaconic Acid

scientific article

Identification and function of cyclic nucleotide phosphodiesterase isoenzymes in airway epithelial cells

scientific article published on February 1999

Impact of intravenous {beta}-lactam/macrolide versus {beta}-lactam monotherapy on mortality in hospitalized patients with community-acquired pneumonia

scientific article published on 17 March 2009

Increasing the inspiratory time and I:E ratio during mechanical ventilation aggravates ventilator-induced lung injury in mice

scientific article

Induction of phosphodiesterases 3B, 4A4, 4D1, 4D2, and 4D3 in Jurkat T-cells and in human peripheral blood T-lymphocytes by 8-bromo-cAMP and Gs-coupled receptor agonists. Potential role in beta2-adrenoreceptor desensitization

scientific article

Infection and activation of airway epithelial cells by Chlamydia pneumoniae

scientific article published on 18 October 2000

Inflammasomes in Pneumococcal Infection: Innate Immune Sensing and Bacterial Evasion Strategies

scientific article

Influenza A viruses target type II pneumocytes in the human lung

scientific article

Influenza vaccination is associated with reduced severity of community-acquired pneumonia

scientific article published on 9 December 2010

Inhibition of cytoskeletal rearrangement by botulinum C2 toxin amplifies ligand-evoked lipid mediator generation in human neutrophils.

scientific article published on October 1991

Innate immune recognition and inflammasome activation in listeria monocytogenes infection

scientific article

Innate immune recognition in infectious and noninfectious diseases of the lung

scientific article published on 18 February 2010

Interaction of human neutrophils with airway epithelial cells: reduction of leukotriene B4 generation by epithelial cell derived prostaglandin E2

scientific article published on 01 June 1998

Intermedin stabilized endothelial barrier function and attenuated ventilator-induced lung injury in mice

scientific article

Intracellular bacteria differentially regulated endothelial cytokine release by MAPK-dependent histone modification

scientific article published in September 2005

Intravenous Artesunate Reduces Parasite Clearance Time, Duration of Intensive Care, and Hospital Treatment in Patients With Severe Malaria in Europe: The TropNet Severe Malaria Study

scientific article published on 17 July 2015

Intravenous Artesunate for Severe Malaria in Travelers, Europe ⬇️

scientific article published on May 1, 2011

Joint tuberculosis caused by Mycobacterium bovis in an immunocompetent patient

scientific article published in September 2000

Legionella pneumophila induces IFNbeta in lung epithelial cells via IPS-1 and IRF3, which also control bacterial replication

scientific article

Legionella pneumophila induces human beta defensin-3 in pulmonary cells.

scientific article published on 8 July 2010

Legionella pneumophila-induced IκBζ-dependent expression of interleukin-6 in lung epithelium.

scientific article published on 22 July 2010

Legionella pneumophila-induced NF-kappaB- and MAPK-dependent cytokine release by lung epithelial cells

scientific article published on 13 September 2006

Legionella pneumophila-induced PKCalpha-, MAPK-, and NF-kappaB-dependent COX-2 expression in human lung epithelium.

scientific article published on 29 September 2006

Leptospirosis in Travelers Returning from the Dominican Republic ⬇️

scientific article published on January 1, 2003

Listeria monocytogenes activated p38 MAPK and induced IL-8 secretion in a nucleotide-binding oligomerization domain 1-dependent manner in endothelial cells

scientific article published in January 2006

Listeria monocytogenes induced Rac1-dependent signal transduction in endothelial cells

scientific article

Listeria monocytogenes potently induces up-regulation of endothelial adhesion molecules and neutrophil adhesion to cultured human endothelial cells

scientific article

Listeria monocytogenes-infected human peripheral blood mononuclear cells produce IL-1beta, depending on listeriolysin O and NLRP3.

scientific article

Lung epithelium as a sentinel and effector system in pneumonia--molecular mechanisms of pathogen recognition and signal transduction

scientific article published on 8 July 2006

Malaria transmission in non-endemic areas: case report, review of the literature and implications for public health management

scientific article

Malarone treatment failure not associated with previously described mutations in the cytochrome b gene

scientific article published on 8 June 2004

Mechanical ventilation drives pneumococcal pneumonia into lung injury and sepsis in mice: protection by adrenomedullin

scientific article

Mechanism of leukotriene generation in polymorphonuclear leukocytes by staphylococcal alpha-toxin

scientific article

Mechanisms of Chlamydophila pneumoniae-mediated GM-CSF release in human bronchial epithelial cells

scientific article published on 09 December 2005

Medical intensive care: new career prospects in internal medicine ⬇️

scientific article published on November 6, 2012

Modifying Post-Operative Medical Care after EBV Implant May Reduce Pneumothorax Incidence

scientific article published on 26 May 2015

Moraxella catarrhalis induces ERK- and NF-kappaB-dependent COX-2 and prostaglandin E2 in lung epithelium.

scientific article published on 30 May 2007

Moraxella catarrhalis induces an immune response in the murine lung that is independent of human CEACAM5 expression and long-term smoke exposure

scientific article published on 5 June 2015

Moraxella catarrhalis induces inflammatory response of bronchial epithelial cells via MAPK and NF-kappaB activation and histone deacetylase activity reduction

scientific article published on 6 January 2006

Moraxella catarrhalis is internalized in respiratory epithelial cells by a trigger-like mechanism and initiates a TLR2- and partly NOD1-dependent inflammatory immune response

scientific article published on 18 October 2006

Moraxella catarrhalis--infected alveolar epithelium induced monocyte recruitment and oxidative burst

scientific article

Moxifloxacin is not anti-inflammatory in experimental pneumococcal pneumonia

scientific article published on 17 November 2014

Moxifloxacin monotherapy versus ß-lactam mono- or combination therapy in hospitalized patients with community-acquired pneumonia

scientific article published on 27 January 2011

Mycoplasma pneumoniae pneumonia revisited within the German Competence Network for Community-acquired pneumonia (CAPNETZ).

scientific article

NAIP and Ipaf control Legionella pneumophila replication in human cells.

scientific article

NLRP3 protects alveolar barrier integrity by an inflammasome-independent increase of epithelial cell adherence.

scientific article published on August 2016

NOD-Like Receptors in Lung Diseases

scientific article

New Pathogenetic Concepts and Pharmacological Studies on Adjuvant Therapy in Severe Pneumonia

scientific article published on 4 December 2015

New aspects of the pathophysiology of pneumonia

scientific article published in May 2007

New therapeutic strategies for community acquired pneumonia

scientific article published in December 2005

Nod1-mediated endothelial cell activation by Chlamydophila pneumoniae

scientific article

Noncytolytic terminal complement complexes may serve as calcium gates to elicit leukotriene B4 generation in human polymorphonuclear leukocytes

Nucleotide oligomerization domain 1 ligation suppressed murine allergen-specific T-cell proliferation and airway hyperresponsiveness

scientific article published on May 2014

Nucleotide-binding oligomerization domain proteins are innate immune receptors for internalized Streptococcus pneumoniae

scientific article published on 23 June 2004

Outcome of community-acquired pneumonia: influence of age, residence status and antimicrobial treatment

scientific article published on 20 February 2008

PKC(alpha) and PKC(epsilon) differentially regulate Legionella pneumophila-induced GM-CSF.

scientific article published on 26 March 2009

PKCα Deficiency in Mice Is Associated with Pulmonary Vascular Hyperresponsiveness to Thromboxane A2 and Increased Thromboxane Receptor Expression

scientific article

Pathogenesis of sepsis syndrome: possible relevance of pore-forming bacterial toxins

scientific article published on January 1996

Perturbation of endothelial junction proteins by Staphylococcus aureus alpha-toxin: inhibition of endothelial gap formation by adrenomedullin

scientific article published on 5 April 2006

Pharmacological and biochemical studies of cytotoxicity of Clostridium novyi type A alpha-toxin

scientific article

Phosphodiesterase 2 inhibition diminished acute lung injury in murine pneumococcal pneumonia

scientific article

Pneumococci induced TLR- and Rac1-dependent NF-kappaB-recruitment to the IL-8 promoter in lung epithelial cells

scientific article published on 18 November 2005

Pneumonia - pathogen-based or constellation-based therapy?

scientific article published in June 2006

Pore-forming bacterial toxins potently induce release of nitric oxide in porcine endothelial cells.

scientific article published on July 1993

Porphyromonas gingivalis strain-dependent activation of human endothelial cells

scientific article published on October 2004

Procalcitonin predicts patients at low risk of death from community-acquired pneumonia across all CRB-65 classes

scientific article published on 24 October 2007

Proteases as mediators of pulmonary vascular permeability

scientific article

Proteinaceous bacterial toxins and pathogenesis of sepsis syndrome and septic shock: the unknown connection

scientific article published on July 1994

Pseudomonas aeruginosa cytotoxin stimulates prostacyclin production in cultured pulmonary artery endothelial cells: Membrane attack and calcium influx

scientific article published on 01 April 1985

Rac1 regulates the NLRP3 inflammasome which mediates IL-1beta production in Chlamydophila pneumoniae infected human mononuclear cells

scientific article

Recognition of Streptococcus pneumoniae by the innate immune system ⬇️

scientific article published on 08 February 2012

Regulation of interleukin IL-4, IL-13, IL-10, and their downstream components in lipopolysaccharide-exposed rat lungs. Comparison of the constitutive expression between rats and humans

scientific journal article

Relative frequency of malaria pigment-carrying monocytes of nonimmune and semi-immune patients from flow cytometric depolarized side scatter

scientific article

Reply to Fujino et al ⬇️

scientific article published on November 29, 2012

Rho protein inactivation induced apoptosis of cultured human endothelial cells

scientific article

Rho protein inhibition blocks cyclooxygenase-2 expression by proinflammatory mediators in endothelial cells

scientific article

Rho protein inhibition blocks protein kinase C translocation and activation

scientific article published on 01 April 1998

Rho proteins and the p38-MAPK pathway are important mediators for LPS-induced interleukin-8 expression in human endothelial cells

scientific article published on 01 May 2000

Role of Ca2+ and Mg2+ for endothelial permeability of water and albumin in vitro

Role of Membrane Lipids in the Pulmonary Vascular Abnormalities Caused by Bacterial Toxins

scientific article published on 01 August 1987

Role of actin and myosin in the control of paracellular permeability in pig, rat and human vascular endothelium

scientific article

Role of endothelial cytoskeleton in high-permeability edema due to botulinum C2 toxin in perfused rabbit lungs

scientific article published on 01 May 1995

Role of local pulmonary IFN-gamma expression in murine allergic airway inflammation

scientific article published on 16 March 2006

Role of nitric oxide and phosphodiesterase isoenzyme II for reduction of endothelial hyperpermeability.

scientific article

Role of pneumolysin for the development of acute lung injury in pneumococcal pneumonia.

scientific article published in July 2006

Selective induction of nerve growth factor and brain-derived neurotrophic factor by LPS and allergen in dendritic cells.

scientific article published on 20 December 2007

Sensitivity of hemozoin detection by automated flow cytometry in non- and semi-immune malaria patients

scientific article

Serotype 1 and 8 Pneumococci Evade Sensing by Inflammasomes in Human Lung Tissue

scientific article published on 28 August 2015

Serum cortisol predicts death and critical disease independently of CRB-65 score in community-acquired pneumonia: a prospective observational cohort study

scientific article

Severe malaria in Europe: an 8-year multi-centre observational study.

scientific article published on 31 January 2017

Signal transduction pathways activated in endothelial cells following infection with Chlamydia pneumoniae.

scientific article published on April 1999

Simvastatin Attenuates Ventilator-induced Lung Injury In Mice

scholarly article published May 2010

Simvastatin attenuates ventilator-induced lung injury in mice

scientific article

Simvastatin reduces Chlamydophila pneumoniae-mediated histone modifications and gene expression in cultured human endothelial cells

scientific article published on 28 February 2008

Spectrum of pathogen- and model-specific histopathologies in mouse models of acute pneumonia

scientific article

Spleen tyrosine kinase inhibition blocks airway constriction and protects from Th2-induced airway inflammation and remodeling

scientific article

Staphylococcal alpha-toxin-induced PGI2 production in endothelial cells: role of calcium

scientific article published on 01 January 1985

Staphylococcal alpha-toxin-induced vascular leakage in isolated perfused rabbit lungs

scientific article published on September 1990

Statins control oxidized LDL-mediated histone modifications and gene expression in cultured human endothelial cells.

scientific article published on 2 January 2009

Stimulation of arachidonate metabolism by endotoxin and the terminal complement complex C5b-8.

scientific article

Streptococcus pneumoniae R6x induced p38 MAPK and JNK-mediated caspase-dependent apoptosis in human endothelial cells

scientific article published in August 2005

Streptococcus pneumoniae induced c-Jun-N-terminal kinase- and AP-1 -dependent IL-8 release by lung epithelial BEAS-2B cells

scientific article published on 12 July 2006

Streptococcus pneumoniae induced p38 MAPK- and NF-kappaB-dependent COX-2 expression in human lung epithelium

scientific article

Streptococcus pneumoniae-induced caspase 6-dependent apoptosis in lung epithelium

scientific article published on September 2004

Streptococcus pneumoniae-induced p38 MAPK-dependent phosphorylation of RelA at the interleukin-8 promotor

scientific article published on 13 October 2004

Streptococcus pneumoniae-induced regulation of cyclooxygenase-2 in human lung tissue ⬇️

scientific article published on March 22, 2012

Streptococcus pneumoniaeinduces human β-defensin-2 and -3 in human lung epithelium ⬇️

scientific article published on March 1, 2012

Suppression of pulmonary innate host defence in smokers

scientific article

TLR2- and nucleotide-binding oligomerization domain 2-dependent Krüppel-like factor 2 expression downregulates NF-kappa B-related gene expression.

scientific article

TLR9- and Src-dependent expression of Krueppel-like factor 4 controls interleukin-10 expression in pneumonia

scientific article

The C-type lectin receptor Mincle binds to Streptococcus pneumoniae but plays a limited role in the anti-pneumococcal innate immune response

scientific article

The UspA1 protein of Moraxella catarrhalis induces CEACAM-1-dependent apoptosis in alveolar epithelial cells

scientific article published on 26 April 2007

The burden of pneumococcal pneumonia - experience of the German competence network CAPNETZ.

scientific article published on 8 August 2012

The chronic critically ill patient ⬇️

scientific article published on 01 May 2013

The common HAQ STING variant impairs cGAS-dependent antibacterial responses and is associated with susceptibility to Legionnaires' disease in humans.

scientific article published on 3 January 2018

The glutathione redox cycle as a defense system against hydrogen-peroxide-induced prostanoid formation and vasoconstriction in rabbit lungs

article published in 1986

The novel human influenza A(H7N9) virus is naturally adapted to efficient growth in human lung tissue.

scientific article

Therapeutic strategies in pneumonia: going beyond antibiotics

scientific article

Three cases of a fulminant course of idiopathic pulmonary fibrosis (Hamman-Rich syndrome)

scientific article published on October 1993

Thromboxane-mediated hypertension and vascular leakage evoked by low doses of Escherichia coli hemolysin in rabbit lungs

scientific article published on July 1989

Topical cidofovir is effective in treating extensive penile condylomata acuminata

scientific article published on 01 May 2000

Tumor necrosis factor-alpha-dependent expression of phosphodiesterase 2: role in endothelial hyperpermeability

scientific article

Twice-weekly pyrimethamine-sulfadoxine effectively prevents Pneumocystis carinii pneumonia relapse and toxoplasmic encephalitis in patients with AIDS.

scientific article

Two distinct phospholipases C of Listeria monocytogenes induce ceramide generation, nuclear factor-kappa B activation, and E-selectin expression in human endothelial cells

scientific article published on 01 September 1998

VEGF induces hyperpermeability by a direct action on endothelial cells.

scientific article published in May 1998

Ventilator-associated pneumonia

scientific article published in August 2013

[Acute Respiratory Failure after Silicone Injection]

scientific article published on 09 September 2019

[Management of a new influenza A/H1N1 virus pandemic within the hospital. Statement of the German Society of Pneumology].

scientific article

[Management of a new influenza A/H1N1 virus pandemic within the hospital: statement of the German Society of Pneumology].

scientific article

[Molecular basis for the pathogenicity of S. aureus alpha-toxins]

scientific article published on 01 November 1984

[SARS--Severe Acute Respiratory syndrome]

scientific article published on 01 May 2003

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