List of works by Joachim Spranger

A distinct metabolic signature predicts development of fasting plasma glucose

scientific article published on 2 February 2012

A genome-wide association search for type 2 diabetes genes in African Americans

scientific article published on 4 January 2012

A high normal TSH is associated with the metabolic syndrome.

scientific article published in May 2010

A polymorphism within the connective tissue growth factor (CTGF) gene has no effect on non-invasive markers of beta-cell area and risk of type 2 diabetes

scientific article published on January 2011

A1C is associated with intima-media thickness in individuals with normal glucose tolerance

scientific article

ANGPTL8 (Betatrophin) is Expressed in Visceral Adipose Tissue and Relates to Human Hepatic Steatosis in Two Independent Clinical Collectives

scientific article published on 28 March 2017

ANP system activity predicts variability of fat mass reduction and insulin sensitivity during weight loss

scientific article

Acetylsalicylic acid improves lipid-induced insulin resistance in healthy men

scientific article (publication date: March 2006)

Acute hyperinsulinaemia and hyperlipidaemia modify circulating adiponectin and its oligomers

scientific article published in October 2009

Adiponectin and protection against type 2 diabetes mellitus

scientific article

Adiponectin does not cross the blood-brain barrier but modifies cytokine expression of brain endothelial cells

scientific article

Adiponectin is independently associated with insulin sensitivity in women with polycystic ovary syndrome.

scientific article published in December 2004

Age- and sex-specific reference intervals across life span for insulin-like growth factor binding protein 3 (IGFBP-3) and the IGF-I to IGFBP-3 ratio measured by new automated chemiluminescence assays

scientific article published on 31 January 2014

Alterations of retinol-binding protein 4 species in patients with different stages of chronic kidney disease and their relation to lipid parameters.

scientific article

An Integrated Understanding of the Molecular Mechanisms How Adipose Tissue Metabolism Affects Long-Term Body Weight Maintenance

scientific article published on 02 November 2018

An accurate risk score based on anthropometric, dietary, and lifestyle factors to predict the development of type 2 diabetes

scientific article published in March 2007

An epigenome-wide association study in whole blood of measures of adiposity among Ghanaians: the RODAM study

scientific article published on 21 September 2017

Androgen receptor CAG repeat length polymorphism modifies the impact of testosterone on insulin sensitivity in men.

scientific article published on 28 March 2011

Arginine vasopressin-dependent and AVP-independent mechanisms of renal fluid absorption during thirsting despite glucocorticoid-mediated vasopressin suppression.

scientific article

Association between C reactive protein and microvascular and macrovascular dysfunction in sub-Saharan Africans with and without diabetes: the RODAM study

scientific article published on 01 July 2020

Association of prostaglandin E synthase 2 (PTGES2) Arg298His polymorphism with type 2 diabetes in two German study populations

scientific article

Attachment style contributes to the outcome of a multimodal lifestyle intervention

scientific article published on 2 February 2012

B vitamin plasma levels and the risk of ischemic stroke and transient ischemic attack in a German cohort

scientific article published on 20 September 2007

Body mass index and C-174G interleukin-6 promoter polymorphism interact in predicting type 2 diabetes

scientific article published in April 2004

Caloric Restriction in Older Adults-Differential Effects of Weight Loss and Reduced Weight on Brain Structure and Function

scientific article published on February 2016

Caloric restriction chronically impairs metabolic programming in mice

scientific article

Cardiovascular disease risk prediction in sub-Saharan African populations — Comparative analysis of risk algorithms in the RODAM study

scientific article

Cell-type specific regulation of the human 11beta-hydroxysteroid dehydrogenase type 1 promoter

scientific article

Cereal fiber improves whole-body insulin sensitivity in overweight and obese women

scientific article published on 01 April 2006

Changes of adiponectin oligomer composition by moderate weight reduction

scientific article published in September 2005

Chemerin and prediction of Diabetes mellitus type 2.

scientific article published on 30 January 2015

Chronic Activation of Hepatic Nrf2 Has No Major Effect on Fatty Acid and Glucose Metabolism in Adult Mice

scientific article

Chronic kidney disease burden among African migrants in three European countries and in urban and rural Ghana: The RODAM cross-sectional study

scientific article published on 12 January 2018

Circulating vaspin is unrelated to insulin sensitivity in a cohort of nondiabetic humans

scientific article published in December 2009

Clinical implications of the EGF receptor/ligand system for tumor progression and survival in gastrointestinal carcinomas: evidence for new therapeutic options.

scientific article

Comparison of relative and attributable risk of myocardial infarction and stroke according to C-reactive protein and low-density lipoprotein cholesterol levels

scientific article (publication date: 2007)

Comprehensive two-dimensional gas chromatography–time-of-flight mass spectrometry (GC × GC-TOF) for high resolution metabolomics: biomarker discovery on spleen tissue extracts of obese NZO compared to lean C57BL/6 mice

article

Correction: Chronic Activation of Hepatic Nrf2 Has No Major Effect on Fatty Acid and Glucose Metabolism in Adult Mice

scientific article published on 16 February 2017

Critical illness myopathy and GLUT4: significance of insulin and muscle contraction

scientific article published on 13 December 2012

Cross-sectional study of association between socioeconomic indicators and chronic kidney disease in rural-urban Ghana: The RODAM study

scientific article

Decision trees as a simple-to-use and reliable tool to identify individuals with impaired glucose metabolism or type 2 diabetes mellitus ⬇️

scientific article published on August 6, 2010

Deletion of the Mammalian INDY Homolog Mimics Aspects of Dietary Restriction and Protects against Adiposity and Insulin Resistance in Mice

scholarly article by Andreas L. Birkenfeld et al published October 2011 in Cell Metabolism

Deletion of the mammalian INDY homolog mimics aspects of dietary restriction and protects against adiposity and insulin resistance in mice

scientific article

Diabetes mellitus type 2 in urban Ghana: characteristics and associated factors

scientific article

Dietary patterns and type 2 diabetes among Ghanaian migrants in Europe and their compatriots in Ghana: The RODAM study

scientific article published on 25 April 2018

Distinct Housing Conditions Reveal a Major Impact of Adaptive Immunity on the Course of Obesity-Induced Type 2 Diabetes.

scientific article

Distinct housing conditions reveal a major impact of adaptive immunity on the course of obesity-induced type 2 diabetes

Dynamics of myosin degradation in intensive care unit-acquired weakness during severe critical illness

scientific article published on 15 February 2014

EFhd2/Swiprosin-1 is a common genetic determinator for sensation-seeking/low anxiety and alcohol addiction.

scientific article

Early type II fiber atrophy in intensive care unit patients with nonexcitable muscle membrane

scientific article published in February 2012

Effect of meglitinides on postprandial ghrelin secretion pattern in type 2 diabetes mellitus

scientific article published in January 2010

Effects of a combined dietary, exercise and behavioral intervention and sympathetic system on body weight maintenance after intended weight loss: results of a randomized controlled trial

scientific article published on 19 January 2018

Effects of caloric restriction on the gut microbiome are linked with immune senescence

scientific article published in 2022

Effects of pronounced weight loss on adiponectin oligomer composition and metabolic parameters.

scientific article

Epigenome-wide association study in whole blood on type 2 diabetes among sub-Saharan African individuals: findings from the RODAM study

Erratum: New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk

scientific article published in May 2010

Evidence that kidney function but not type 2 diabetes determines retinol-binding protein 4 serum levels

scientific article published on 16 September 2008

Factors that influence retinol-binding protein 4-transthyretin interaction are not altered in overweight subjects and overweight subjects with type 2 diabetes mellitus.

scientific article

Fatty acids differentially modify the expression of urokinase type plasminogen activator receptor in monocytes.

scientific article

Fibroblast growth factor 21 mediates specific glucagon actions

scientific article published on 10 January 2013

Fibroblast growth factor 21 predicts the metabolic syndrome and type 2 diabetes in Caucasians

scientific article

Frataxin deficiency in pancreatic islets causes diabetes due to loss of beta cell mass

scientific article

Frataxin deficiency in pancreatic islets causes diabetes due to loss of β cell mass

article published in 2003

Free fatty acids link metabolism and regulation of the insulin-sensitizing fibroblast growth factor-21.

scientific article published on 28 April 2009

GLP-1-based therapies: the dilemma of uncertainty

scientific article published in July 2011

Genetic Nicotinamide N-Methyltransferase (Nnmt) Deficiency in Male Mice Improves Insulin Sensitivity in Diet-Induced Obesity but Does Not Affect Glucose Tolerance

scientific article published on 14 December 2018

Genetic variation in GPR133 is associated with height: genome wide association study in the self-contained population of Sorbs

scientific article published on 03 September 2009

Genome wide meta-analysis identifies novel determinants of circulating serum progranulin

scientific article published on 27 November 2017

Glucose-dependent insulinotropic polypeptide reduces fat-specific expression and activity of 11β-hydroxysteroid dehydrogenase type 1 and inhibits release of free fatty acids

scientific article published on 16 December 2011

Growth hormone response during oral glucose tolerance test: the impact of assay method on the estimation of reference values in patients with acromegaly and in healthy controls, and the role of gender, age, and body mass index.

scientific article published on 2 January 2008

Hepatic insulin clearance is closely related to metabolic syndrome components

scientific article published on 11 September 2013

High prevalence of anaemia among African migrants in Germany persists after exclusion of iron deficiency and erythrocyte polymorphisms

scientific article published on 5 May 2015

High-Saturated-Fat Diet Increases Circulating Angiotensin-Converting Enzyme, Which Is Enhanced by the rs4343 Polymorphism Defining Persons at Risk of Nutrient-Dependent Increases of Blood Pressure

scientific article published on 17 January 2017

High-fat diet-induced obesity and insulin resistance are characterized by differential beta oscillatory signaling of the limbic cortico-basal ganglia loop

scientific article published on 14 November 2017

High-mobility group A1 protein: a new coregulator of peroxisome proliferator-activated receptor-γ-mediated transrepression in the vasculature.

scientific article

Histone deacetylase 6 (HDAC6) is an essential modifier of glucocorticoid-induced hepatic gluconeogenesis

scientific article published on 30 December 2011

Hypoxia and exercise interactions on skeletal muscle insulin sensitivity in obese subjects with metabolic syndrome: results of a randomized controlled trial

scientific article published on 09 December 2019

IL6 gene promoter polymorphisms and type 2 diabetes: joint analysis of individual participants' data from 21 studies

scientific article

Ideal cardiovascular health among Ghanaian populations in three European countries and rural and urban Ghana: the RODAM study

scientific article published on 17 April 2018

Identification of a functional protein kinase Cbeta promoter polymorphism in humans related to insulin resistance

scientific article published on 22 October 2007

Impact of type 2 diabetes susceptibility variants on quantitative glycemic traits reveals mechanistic heterogeneity

scientific article

Impulse control in the dorsolateral prefrontal cortex counteracts post-diet weight regain in obesity

scientific article published on 7 January 2015

Inflammation-induced acute phase response in skeletal muscle and critical illness myopathy

scientific article

Inflammatory cytokines and the risk to develop type 2 diabetes: results of the prospective population-based European Prospective Investigation into Cancer and Nutrition (EPIC)-Potsdam Study

scientific article published on March 2003

Influences of levodopa on adipose tissue and skeletal muscle metabolism in patients with idiopathic Parkinson's disease

scientific article published on 30 July 2008

Inhibition of citrate cotransporter Slc13a5/mINDY by RNAi improves hepatic insulin sensitivity and prevents diet-induced non-alcoholic fatty liver disease in mice

scientific article

Insulin-Like Growth Factor (IGF) Binding Protein-2, Independently of IGF-1, Induces GLUT-4 Translocation and Glucose Uptake in 3T3-L1 Adipocytes

scientific article published on 20 December 2017

Interactions between neural decision-making circuits predict long-term dietary treatment success in obesity

scientific article published on 22 September 2018

Interindividual Variation in DNA Methylation at a Putative POMC Metastable Epiallele Is Associated with Obesity

scientific article

Interleukin-6 g.−174G>C Promoter Polymorphism Is Associated with Obesity in the EPIC-Potsdam Study*

scholarly article by Kerstin Klipstein-Grobusch et al published January 2006 in Obesity

KCNJ11 E23K Affects Diabetes Risk and Is Associated With the Disposition Index: Results of two independent German cohorts

article

Knockdown of Indy/CeNac2 extends Caenorhabditis elegans life span by inducing AMPK/aak-2

scientific article

L-FABP T94A is associated with fasting triglycerides and LDL-cholesterol in women

scientific article published on 7 May 2007

Lack of association between the tagging SNP A+930-->G of SOCS3 and type 2 diabetes mellitus: meta-analysis of four independent study populations

scientific article

Long-term risk of incident type 2 diabetes and measures of overall and regional obesity: the EPIC-InterAct case-cohort study

scientific article

MC4R agonism promotes durable weight loss in patients with leptin receptor deficiency

Medication non-adherence and blood pressure control among hypertensive migrant and non-migrant populations of sub-Saharan African origin: the RODAM study

Metabolic actions of natriuretic peptides and therapeutic potential in the metabolic syndrome.

scientific article

Metabolomic linkage reveals functional interaction between glucose-dependent insulinotropic polypeptide and ghrelin in humans

scientific article published on 17 May 2011

Microvascular and macrovascular complications in type 2 diabetes Ghanaian residents in Ghana and Europe: The RODAM study

scientific article published on 10 May 2019

Migration and Cardiovascular Disease Risk Among Ghanaian Populations in Europe: The RODAM Study (Research on Obesity and Diabetes Among African Migrants).

scientific article published in November 2017

Molecular and clinical evidence for an ARMC5 tumor syndrome: concurrent inactivating germline and somatic mutations are associated with both primary macronodular adrenal hyperplasia and meningioma

scientific article

New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk

scientific article

Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals

scientific article

Obesity and type 2 diabetes in sub-Saharan Africans - Is the burden in today's Africa similar to African migrants in Europe? The RODAM study.

scientific article

Palliative treatment of uncontrollable hypercalcemia due to parathyrotoxicosis: denosumab as rescue therapy

scientific article

Peripheral insulin resistance rather than beta cell dysfunction accounts for geographical differences in impaired fasting blood glucose among sub-Saharan African individuals: findings from the RODAM study

scientific article published on 31 January 2017

Physiological modulation of circulating FGF21: relevance of free fatty acids and insulin.

scientific article published on 27 April 2010

Plasma gamma-glutamyltransferase, cysteinyl-glycine, and oxidized low-density lipoprotein: a pathway associated with myocardial infarction risk?

scientific article published on 29 July 2010

Plasma pyridoxal-5-phosphate and future risk of myocardial infarction in the European Prospective Investigation into Cancer and Nutrition Potsdam cohort

scientific article published on July 2007

Plasma resistin levels and risk of myocardial infarction and ischemic stroke

scientific article published on 6 May 2008

Polymorphisms within insulin-degrading enzyme (IDE) gene determine insulin metabolism and risk of type 2 diabetes

scientific article

Predictors of abnormal glucose metabolism in women with polycystic ovary syndrome.

scientific article published in February 2006

Psychodynamic mechanism and weight reduction in obesity group therapy - first observations with different attachment styles ⬇️

scientific article published on August 31, 2010

Putative association between a new polymorphism in exon 3 (Arg109Cys) of the pancreatic colipase gene and type 2 diabetes mellitus in two independent Caucasian study populations

scientific article

Rationale and cross-sectional study design of the research on obesity and type 2 diabetes among African migrants: The RODAM study

scientific article

Reference intervals for insulin-like growth factor-1 (igf-i) from birth to senescence: results from a multicenter study using a new automated chemiluminescence IGF-I immunoassay conforming to recent international recommendations

scientific article

Relation between fibroblast growth factor-21, adiposity, metabolism, and weight reduction

scientific article published in April 2010

Relation between physiological variation of renal function and carotid intima media thickness in non-diabetic individuals.

scientific article published on 24 December 2009

Relation between retinol, retinol-binding protein 4, transthyretin and carotid intima media thickness

scientific article published on 19 August 2010

Renal function is independently associated with circulating betatrophin

scientific article

Retinol-binding protein 4 is associated with insulin resistance, but appears unsuited for metabolic screening in women with polycystic ovary syndrome.

scientific article

Risk factors in critical illness myopathy during the early course of critical illness: a prospective observational study

scientific article

Role of genetic variation in the human sodium-glucose cotransporter 2 gene (SGLT2) in glucose homeostasis

scientific article published on 10 August 2011

Rosiglitazone decreases 11beta-hydroxysteroid dehydrogenase type 1 in subcutaneous adipose tissue.

scientific article published on 6 June 2007

Rosiglitazone increases fatty acid Δ9-desaturation and decreases elongase activity index in human skeletal muscle in vivo

scientific article published on 7 July 2011

Sex differences in physiological cardiac hypertrophy are associated with exercise-mediated changes in energy substrate availability.

scientific article

Sexual dimorphic regulation of body weight dynamics and adipose tissue lipolysis

scientific article

Skeletal muscle 11beta-HSD1 controls glucocorticoid-induced proteolysis and expression of E3 ubiquitin ligases atrogin-1 and MuRF-1.

scientific article

Skepticism is unjustified

scientific article published on June 2014

Specific skeletal muscle sphingolipid compounds in energy expenditure regulation and weight gain in Native Americans of Southwestern heritage.

scientific article

Statistical methods for comparing comprehensive two-dimensional gas chromatography–time-of-flight mass spectrometry results: Metabolomic analysis of mouse tissue extracts

article

THOC5: a novel gene involved in HDL-cholesterol metabolism

scientific article published on 10 September 2013

The androgen receptor CAG repeat modifies the impact of testosterone on insulin resistance in women with polycystic ovary syndrome.

scientific article published in July 2006

The polycystic ovary syndrome per se is not associated with increased chronic inflammation

scientific article published in April 2004

The role of insulin-like growth factor (IGF) binding protein-2 in the insulin-mediated decrease in IGF-I bioactivity

scientific article published on 21 October 2009

The role of neural impulse control mechanisms for dietary success in obesity

scientific article

Type 2 diabetes mellitus management among Ghanaian migrants resident in three European countries and their compatriots in rural and urban Ghana – The RODAM study

scientific article published in December 2017

Untargeted metabolic profiling identifies altered serum metabolites of type 2 diabetes mellitus in a prospective, nested case control study

article by Dagmar Drogan et al published March 2015 in Clinical Chemistry

Variations in hypertension awareness, treatment, and control among Ghanaian migrants living in Amsterdam, Berlin, London, and nonmigrant Ghanaians living in rural and urban Ghana-the RODAM study

scientific article published on 29 August 2017

Weight Loss Partially Restores Glucose-Driven Betatrophin Response in Humans

scientific article published on 26 July 2016

Wheat-fibre-induced changes of postprandial peptide YY and ghrelin responses are not associated with acute alterations of satiety

scientific article published in November 2006

Whole-body vibration to prevent intensive care unit-acquired weakness: safety, feasibility, and metabolic response

scientific article published on 09 January 2017

[Depot insulin with tumor risk. Changing now or staying cool? (interview by Sarah Pampel)].

scientific article published in July 2009

[Pathophysiology of impaired insulin sensitivity in the perioperative period].

scientific article published on 11 April 2011

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