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List of works by Jennifer C Lee

5-fluoro-D,L-tryptophan as a dual NMR and fluorescent probe of α-synuclein

scientific article

Alpha-synuclein lipid-dependent membrane binding and translocation through the α-hemolysin channel

scientific article

Alpha-synuclein structures from fluorescence energy-transfer kinetics: implications for the role of the protein in Parkinson's disease

scholarly article

Amyloid triangles, squares, and loops of apolipoprotein C-III.

scientific article

Apolipoprotein C-III Nanodiscs Studied by Site-Specific Tryptophan Fluorescence

scientific article

Biophysics of α-synuclein membrane interactions.

scientific article

C-terminal α-synuclein truncations are linked to cysteine cathepsin activity in Parkinson's disease

scientific article published on 15 May 2019

Copper(ii) enhances membrane-bound α-synuclein helix formation ⬇️

scientific article published on February 3, 2011

Cysteine cathepsins are essential in lysosomal degradation of α-synuclein.

scientific article published on 13 July 2015

Defining an amyloid link Between Parkinson's disease and melanoma

scientific article published on 31 August 2020

Depth of α-synuclein in a bilayer determined by fluorescence, neutron reflectometry, and computation.

scientific article published on 7 February 2012

Dissociation of glucocerebrosidase dimer in solution by its co-factor, saposin C.

scientific article

Effect of dioxygen on copper(II) binding to alpha-synuclein.

scientific article

Effects of pH on aggregation kinetics of the repeat domain of a functional amyloid, Pmel17.

scientific article

Effects of phosphatidylcholine membrane fluidity on the conformation and aggregation of N-terminally acetylated α-synuclein

scientific article published on 31 May 2018

Emerging insights into the mechanistic link between α-synuclein and glucocerebrosidase in Parkinson's disease

scientific article

Energy transfer ligands of the GluR2 ligand binding core

scientific article

Equilibrium unfolding of the poly(glutamic acid)20 helix

scientific article published on 01 June 2007

Evidence for copper-dioxygen reactivity during alpha-synuclein fibril formation.

scientific article

Fate plasticity and reprogramming in genetically distinct populations of Danio leucophores.

scientific article published on 28 May 2019

Folding energy landscape of cytochrome cb562

scholarly article

Identification of the minimal copper(II)-binding alpha-synuclein sequence.

scientific article published on October 2009

Interplay between α-synuclein amyloid formation and membrane structure

scientific article published on 02 October 2018

Lipid-Chaperone Hypothesis: A Common Molecular Mechanism of Membrane Disruption by Intrinsically Disordered Proteins

scientific article published on 03 December 2020

Lysophospholipid-containing membranes modulate the fibril formation of the repeat domain of a human functional amyloid, pmel17.

scientific article

Lysophospholipids induce fibrillation of the repeat domain of Pmel17 through intermediate core-shell structures

scientific article published on 22 November 2018

Mechanism of assembly of the non-covalent spectrin tetramerization domain from intrinsically disordered partners

scientific article published on 17 September 2013

Membrane Interactions of α-Synuclein Probed by Neutrons and Photons

scientific article published on 08 January 2021

Membrane remodeling by α-synuclein and effects on amyloid formation.

scientific article published on 17 October 2013

Membrane-bound α-synuclein interacts with glucocerebrosidase and inhibits enzyme activity.

scientific article published on 28 November 2012

Modulating functional amyloid formation via alternative splicing of the premelanosomal protein PMEL17

scientific article published on 10 April 2020

Molecular origin of pH-dependent fibril formation of a functional amyloid

scientific article

N-Terminal Acetylation Affects α-Synuclein Fibril Polymorphism

scientific article published on 21 August 2019

NMR Structure of Calmodulin Complexed to an N-Terminally Acetylated α-Synuclein Peptide

scientific article

Physical Chemistry in Biomedical Research: From Cuvettes toward Cellular Insights.

scientific article

Probing Membrane Association of α-Synuclein Domains with VDAC Nanopore Reveals Unexpected Binding Pattern

scientific article published on 14 March 2019

Probing fibril dissolution of the repeat domain of a functional amyloid, Pmel17, on the microscopic and residue level

scientific article published on 17 November 2011

Raman fingerprints of amyloid structures

scholarly article by Jessica D Flynn & Jennifer C Lee published 21 June 2018 in Chemical Communications

Residue-specific fluorescent probes of α-synuclein: detection of early events at the N- and C-termini during fibril assembly

scientific article

Reversing the amyloid trend: Mechanism of fibril assembly and dissolution of the repeat domain from a human functional amyloid

scientific article

Saposin C protects glucocerebrosidase against α-synuclein inhibition.

scientific article published on October 2013

Segmental Deuteration of α-Synuclein for Neutron Reflectometry on Tethered Bilayers.

scientific article

Segmental ¹³C-labeling and Raman Microspectroscopy of α-Synuclein Amyloid Formation

scientific article published on 27 November 2018

Single-Particle Tracking of Human Lipoproteins

scientific article

Spermine binding to Parkinson's protein alpha-synuclein and its disease-related A30P and A53T mutants

scientific article published on 09 August 2008

Stimulation of α-synuclein amyloid formation by phosphatidylglycerol micellar tubules.

scientific article published in March 2018

Structural Insights into α-Synuclein Fibril Polymorphism: Effects of Parkinson's Disease-Related C-Terminal Truncations

scientific article published on 08 July 2019

Structural features of cytochrome c' folding intermediates revealed by fluorescence energy-transfer kinetics

scientific article

Structural features of membrane-bound glucocerebrosidase and α-synuclein probed by neutron reflectometry and fluorescence spectroscopy.

scientific article

Structural features of α-synuclein amyloid fibrils revealed by Raman spectroscopy

scientific article published on 30 November 2017

Taking a Bite Out of Amyloid: Mechanistic Insights into α-Synuclein Degradation by Cathepsin L.

scientific article published on 14 June 2017

Terminal Alkynes as Raman Probes of α-Synuclein in Solution and in Cells

scientific article published on 21 January 2020

The yin and yang of amyloid: insights from α-synuclein and repeat domain of Pmel17

scientific article published on 12 October 2011

Tryptophan probes at the alpha-synuclein and membrane interface.

scientific article

Tryptophan probes reveal residue-specific phospholipid interactions of apolipoprotein C-III

scientific article

Unroofing site-specific α-synuclein-lipid interactions at the plasma membrane

scientific article published on 27 July 2020

Why Study Functional Amyloids? Lessons from the Repeat Domain of Pmel17

pH-Dependent fibril maturation of a Pmel17 repeat domain isoform revealed by tryptophan fluorescence

scientific article published on 02 February 2019

α-Synuclein Interacts with Glucocerebrosidase Providing a Molecular Link between Parkinson and Gaucher Diseases ⬇️

scientific article published on June 8, 2011

α-Synuclein Shows High Affinity Interaction with Voltage-dependent Anion Channel, Suggesting Mechanisms of Mitochondrial Regulation and Toxicity in Parkinson Disease

scientific article published on 8 June 2015

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