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List of works by Stephan Ripke

A Loss-Of-Function Splice Acceptor Variant in IGF2 is Protective for Type 2 Diabetes

scientific article

A Method to Exploit the Structure of Genetic Ancestry Space to Enhance Case-Control Studies

scientific article published on 13 April 2016

A contribution of novel CNVs to schizophrenia from a genome-wide study of 41,321 subjects

A direct test of the diathesis-stress model for depression.

scientific article published on 11 July 2017

A genome-wide association analysis of a broad psychosis phenotype identifies three loci for further investigation

scientific article published on 17 July 2013

A genome-wide association study identifies a functional ERAP2 haplotype associated with birdshot chorioretinopathy

scientific article (publication date: 15 November 2014)

A genomewide association study points to multiple loci that predict antidepressant drug treatment outcome in depression

scientific article published on September 2009

A mega-analysis of genome-wide association studies for major depressive disorder

scientific article

A novel approach to detect cumulative genetic effects and genetic interactions in Crohn's disease

scientific article published on August 2013

A rare penetrant mutation in CFH confers high risk of age-related macular degeneration.

scientific article published on 23 October 2011

A recessive genetic model and runs of homozygosity in major depressive disorder

scientific article

ASD and schizophrenia show distinct developmental profiles in common genetic overlap with population-based social communication difficulties

scientific article published on 03 January 2017

Acute and chronic nicotine effects on behaviour and brain activation during intertemporal decision making

scientific article published on 16 May 2013

Altered Neural Efficiency of Decision Making During Temporal Reward Discounting in Anorexia Nervosa

scientific article published on 5 September 2016

Altered reward processing in adolescents with prenatal exposure to maternal cigarette smoking

scientific article published on August 2013

Amygdala-function perturbations in healthy mid-adolescents with familial liability for depression.

scientific article published on 14 March 2014

An Analysis of Two Genome-wide Association Meta-analyses Identifies a New Locus for Broad Depression Phenotype

scientific article published on 8 December 2016

An excess of risk-increasing low-frequency variants can be a signal of polygenic inheritance in complex diseases

scientific article

Analysis of rare, exonic variation amongst subjects with autism spectrum disorders and population controls

scientific article

Analysis of shared heritability in common disorders of the brain

scientific article published on 21 June 2018

Analysis of shared heritability in common disorders of the brain

Association analyses identify 38 susceptibility loci for inflammatory bowel disease and highlight shared genetic risk across populations

scientific article published on 20 July 2015

Association of Whole-Genome and NETRIN1 Signaling Pathway–Derived Polygenic Risk Scores for Major Depressive Disorder and White Matter Microstructure in the UK Biobank

scholarly article by Miruna C. Barbu et al published July 2018 in Biological Psychiatry: Cognitive Neuroscience and Neuroimaging

Association of a brain methylation site with clinical outcomes in depression does not replicate across populations

scientific article published in April 2015

Association of granulomatosis with polyangiitis (Wegener's) with HLA-DPB1*04 and SEMA6A gene variants: evidence from genome-wide analysis

scientific article published on September 2013

Association study of common genetic variants and HIV-1 acquisition in 6,300 infected cases and 7,200 controls

scientific article

Associations of CFHR1-CFHR3 deletion and a CFH SNP to age-related macular degeneration are not independent

scientific article published on July 2010

Author Correction: Common and rare variant association analyses in amyotrophic lateral sclerosis identify 15 risk loci with distinct genetic architectures and neuron-specific biology

scientific article

Author Correction: Genome-wide meta-analysis identifies new loci and functional pathways influencing Alzheimer's disease risk

scientific article published on 01 March 2020

Bipolar polygenic loading and bipolar spectrum features in major depressive disorder

scientific article published on 12 April 2014

Case-Control Genome-Wide Association Study of Attention-Deficit/Hyperactivity Disorder ⬇️

scientific article published on August 5, 2010

Classical Human Leukocyte Antigen Alleles and C4 Haplotypes Are Not Significantly Associated With Depression

scientific article published on 05 August 2019

Clozapine-induced agranulocytosis is associated with rare HLA-DQB1 and HLA-B alleles

scientific article

Common alleles contribute to schizophrenia in CNV carriers

Common alleles contribute to schizophrenia in CNV carriers.

scientific article published on 22 September 2015

Common and rare variant association analyses in Amyotrophic Lateral Sclerosis identify 15 risk loci with distinct genetic architectures and neuron-specific biology

preprint

Common and rare variant association analyses in amyotrophic lateral sclerosis identify 15 risk loci with distinct genetic architectures and neuron-specific biology

scholarly article

Common neural correlates of intertemporal choices and intelligence in adolescents

scientific article published in February 2015

Common risk variants identified in autism spectrum disorder

Common schizophrenia alleles are enriched in mutation-intolerant genes and in regions under strong background selection.

scientific article published on 26 February 2018

Common schizophrenia alleles are enriched in mutation-intolerant genes and maintained by background selection

article

Common variants near FRK/COL10A1 and VEGFA are associated with advanced age-related macular degeneration

scientific article

Comparative genetic architectures of schizophrenia in East Asian and European populations

scientific article published on 18 November 2019

Comprehensive analysis of schizophrenia-associated loci highlights ion channel pathways and biologically plausible candidate causal genes

scientific article published on 10 January 2016

Contribution of copy number variants to schizophrenia from a genome-wide study of 41,321 subjects

scientific article

Converging genetic and functional brain imaging evidence links neuronal excitability to working memory, psychiatric disease, and brain activity

scientific article

Copy number variation in bipolar disorder

scientific article published on 06 January 2015

Correction: Improved Detection of Common Variants Associated with Schizophrenia and Bipolar Disorder Using Pleiotropy-Informed Conditional False Discovery Rate

scientific article published on 5 November 2015

Correction: Investigation of the Genetic Association between Quantitative Measures of Psychosis and Schizophrenia: A Polygenic Risk Score Analysis

scientific article published in PLoS ONE

Cortical Surfaces Mediate the Relationship Between Polygenic Scores for Intelligence and General Intelligence

scientific article published on 11 December 2019

Deep resequencing of GWAS loci identifies independent rare variants associated with inflammatory bowel disease

scientific article

Defining the role of common variation in the genomic and biological architecture of adult human height

scientific article

Discovery Of The First Genome-Wide Significant Risk Loci For ADHD

scholarly article published 3 June 2017

Discovery of the first genome-wide significant risk loci for attention deficit/hyperactivity disorder

scientific article published on 26 November 2018

Dissecting the Shared Genetic Architecture of Suicide Attempt, Psychiatric Disorders, and Known Risk Factors

scientific article published in February 2022

Does Childhood Trauma Moderate Polygenic Risk for Depression? A Meta-analysis of 5765 Subjects From the Psychiatric Genomics Consortium

scientific article published on 21 September 2017

Effects of a neurodevelopmental genes based polygenic risk score for schizophrenia and single gene variants on brain structure in non-clinical subjects: A preliminary report

scientific article published on 06 August 2019

Epigenetic variance in dopamine D2 receptor: a marker of IQ malleability?

scientific article published on 30 August 2018

Erratum: Common alleles contribute to schizophrenia in CNV carriers

scholarly article published in Molecular Psychiatry

Erratum: Estimating the proportion of variation in susceptibility to schizophrenia captured by common SNPs

article

Erratum: Identification of increased genetic risk scores for schizophrenia in treatment-resistant patients

scientific article published on 14 April 2015

Estimating the proportion of variation in susceptibility to schizophrenia captured by common SNPs.

scientific article

Estimation of SNP heritability from dense genotype data

scientific article published on December 2013

Evidence for associations between PDE4D polymorphisms and a subtype of neuroticism

scientific article published on 01 September 2008

Evidence of Common Genetic Overlap Between Schizophrenia and Cognition.

scientific article published on 16 December 2015

Exploring adolescent cognitive control in a combined interference switching task

scientific article published on 24 June 2014

Exploring the genetics of irritable bowel syndrome: a GWA study in the general population and replication in multinational case-control cohorts

scientific article published on 23 September 2014

Expression analysis in a rat psychosis model identifies novel candidate genes validated in a large case-control sample of schizophrenia.

scientific article published on 13 October 2015

Fine-mapping classical HLA variation associated with durable host control of HIV-1 infection in African Americans

scientific article

Functional neuroimaging effects of recently discovered genetic risk loci for schizophrenia and polygenic risk profile in five RDoC subdomains

scientific article published on 10 January 2017

GWAS meta-analysis (N=279,930) identifies new genes and functional links to intelligence

article

GWAS of Suicide Attempt in Psychiatric Disorders and Association With Major Depression Polygenic Risk Scores.

scientific article

GenABEL: an R library for genome-wide association analysis

scientific article (publication date: 15 May 2007)

Gene-gene and gene-environment interactions in ulcerative colitis.

scientific article

Genetic Overlap Between Attention-Deficit/Hyperactivity Disorder and Bipolar Disorder: Evidence From Genome-wide Association Study Meta-analysis.

scientific article published on 18 October 2016

Genetic comorbidity between major depression and cardio-metabolic traits, stratified by age at onset of major depression

scientific article published on 18 July 2020

Genetic effects influencing risk for major depressive disorder in China and Europe

scientific article

Genetic influences on schizophrenia and subcortical brain volumes: large-scale proof of concept

scientific article published on February 2016

Genetic markers within glutamate receptors associated with antidepressant treatment-emergent suicidal ideation

scientific article published in July 2008

Genetic meta-analysis identifies 9 novel loci and functional pathways for Alzheimers disease risk

Genetic modifiers and subtypes in schizophrenia: investigations of age at onset, severity, sex and family history

scientific article published on 26 February 2014

Genetic pleiotropy between multiple sclerosis and schizophrenia but not bipolar disorder: differential involvement of immune-related gene loci

scientific article

Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs

scientific article

Genetic risk for autism spectrum disorders and neuropsychiatric variation in the general population

scientific article published on 21 March 2016

Genetic risk variants for social anxiety

scientific article

Genetic risk variants for social anxiety

Genetic schizophrenia risk variants jointly modulate total brain and white matter volume

scientific article published on 3 October 2012

Genetic studies of body mass index yield new insights for obesity biology

scientific article

Genetic studies of major depressive disorder: why are there no genome-wide association study findings and what can we do about it?

scientific article published on October 2014

Genetic variation in soluble epoxide hydrolase (EPHX2) is associated with an increased risk of ischemic stroke in white Europeans

scientific article published on 6 March 2008

Genetic variation in the Major Histocompatibility Complex and association with depression

Genetic variation in the lymphotoxin-alpha pathway and the risk of ischemic stroke in European populations

scientific article published on 29 January 2009

Genome-Wide Association Study Reveals First Locus for Anorexia Nervosa and Metabolic Correlations

scholarly article

Genome-wide Association Studies of Posttraumatic Stress Disorder in 2 Cohorts of US Army Soldiers

scientific article published on 11 May 2016

Genome-wide Association for Major Depression Through Age at Onset Stratification: Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium

scientific article published on 24 May 2016

Genome-wide analyses of psychological resilience in U.S. Army soldiers

scientific article published on 13 May 2019

Genome-wide analysis of insomnia disorder

scientific article published on 8 March 2018

Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression

scientific article published on 26 April 2018

Genome-wide association analysis identifies 13 new risk loci for schizophrenia

scientific article published in October 2013

Genome-wide association analysis identifies 30 new susceptibility loci for schizophrenia

scientific article

Genome-wide association meta-analysis in 269,867 individuals identifies new genetic and functional links to intelligence

article

Genome-wide association study identifies 30 loci associated with bipolar disorder.

scientific article

Genome-wide association study identifies eight risk loci and implicates metabo-psychiatric origins for anorexia nervosa.

scientific article

Genome-wide association study in a Swedish population yields support for greater CNV and MHC involvement in schizophrenia compared with bipolar disorder

scientific journal article

Genome-wide association study of advanced age-related macular degeneration identifies a role of the hepatic lipase gene (LIPC)

scientific article

Genome-wide association study of borderline personality disorder reveals genetic overlap with bipolar disorder, major depression and schizophrenia

scientific article published on 20 June 2017

Genome-wide association study of clinical dimensions of schizophrenia: polygenic effect on disorganized symptoms ⬇️

scientific article

Genome-wide association study of coronary and aortic calcification implicates risk loci for coronary artery disease and myocardial infarction

scientific journal article

Genome-wide association study of intracranial aneurysm identifies a new association on chromosome 7.

scientific article

Genome-wide association study of major depressive disorder: new results, meta-analysis, and lessons learned

scientific article

Genome-wide association study of more than 40,000 bipolar disorder cases provides new insights into the underlying biology

scientific article published in June 2021

Genome-wide association study of multiplex schizophrenia pedigrees.

scientific article

Genome-wide association study of panic disorder reveals genetic overlap with neuroticism and depression

scientific article published on 11 November 2019

Genome-wide association study of restless legs syndrome identifies common variants in three genomic regions

scientific article

Genome-wide association study of suicide attempt in psychiatric disorders identifies association with major depression polygenic risk scores

Genome-wide association study results for educational attainment aid in identifying genetic heterogeneity of schizophrenia

scientific article published in Nature Communications

Genome-wide association study reveals greater polygenic loading for schizophrenia in cases with a family history of illness

scientific article published on 11 December 2015

Genome-wide common and rare variant analysis provides novel insights into clozapine-associated neutropenia

scientific article published on 9 August 2016

Genome-wide common and rare variant analysis provides novel insights into clozapine-associated neutropenia

scientific article published on 24 October 2017

Genome-wide common and rare variant analysis provides novel insights into clozapine-associated neutropenia.

scientific article published on 12 July 2016

Genome-wide gene-environment interaction in depression: A systematic evaluation of candidate genes: The childhood trauma working-group of PGC-MDD.

scientific article published on 21 November 2017

Genome-wide meta-analysis identifies new loci and functional pathways influencing Alzheimer's disease risk

scholarly article by Iris E Jansen et al published March 2019 in Nature Genetics

Genome-wide meta-analysis identifies new loci and functional pathways influencing Alzheimer’s disease risk

Genome-wide meta-analysis in alopecia areata resolves HLA associations and reveals two new susceptibility loci

scientific article published on 22 January 2015

Genome-wide meta-analysis of depression identifies 102 independent variants and highlights the importance of the prefrontal brain regions

scientific article published on 04 February 2019

Genome-wide meta-analysis of depression identifies 102 independent variants and highlights the importance of the prefrontal brain regions.: Supplementary Information

Genomewide association studies of suicide attempts in US soldiers

scientific article published on 13 September 2017

Genomewide association study identifies 30 loci associated with bipolar disorder

Heritability and genome-wide association study to assess genetic differences between advanced age-related macular degeneration subtypes

scientific journal article

High loading of polygenic risk for ADHD in children with comorbid aggression

scientific article published on August 2013

High loading of polygenic risk in cases with chronic schizophrenia

scientific article published on September 2015

High-density mapping of the MHC identifies a shared role for HLA-DRB1*01:03 in inflammatory bowel diseases and heterozygous advantage in ulcerative colitis

scientific article

Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease

scientific article

IL2RA and IL7RA genes confer susceptibility for multiple sclerosis in two independent European populations.

scientific article

Identification of common genetic risk variants for autism spectrum disorder

scientific article published on 25 February 2019

Identification of increased genetic risk scores for schizophrenia in treatment-resistant patients

scientific article published on 3 June 2014

Improved detection of common variants associated with schizophrenia and bipolar disorder using pleiotropy-informed conditional false discovery rate

scientific article

Improving genetic prediction by leveraging genetic correlations among human diseases and traits.

scientific article published on 7 March 2018

Integrated pathway-based approach identifies association between genomic regions at CTCF and CACNB2 and schizophrenia

scientific article

Interaction Testing and Polygenic Risk Scoring to Estimate the Association of Common Genetic Variants With Treatment Resistance in Schizophrenia

scientific article

Interindividual differences in mid-adolescents in error monitoring and post-error adjustment

scientific article

International meta-analysis of PTSD genome-wide association studies identifies sex- and ancestry-specific genetic risk loci

scientific article published on 08 October 2019

Investigating polygenic burden in age at disease onset in bipolar disorder: Findings from an international multicentric study

Investigation of the genetic association between quantitative measures of psychosis and schizophrenia: a polygenic risk score analysis

scientific article (publication date: 2012)

Joint analysis of psychiatric disorders increases accuracy of risk prediction for schizophrenia, bipolar disorder, and major depressive disorder

scientific article

LD Score regression distinguishes confounding from polygenicity in genome-wide association studies

scientific article published on 2 February 2015

Largest GWAS of PTSD (N=20 070) yields genetic overlap with schizophrenia and sex differences in heritability.

scientific article published on 25 April 2017

Largest genome-wide association study for PTSD identifies genetic risk loci in European and African ancestries and implicates novel biological pathways

article published in 2018

Local genetic effects on gene expression across 44 human tissues

article

Mapping genomic loci implicates genes and synaptic biology in schizophrenia

scientific article published on 8 April 2022

Meta-Analysis of Genome-Wide Association Studies of Attention-Deficit/Hyperactivity Disorder ⬇️

scientific article published on August 1, 2010

Mid-adolescent neurocognitive development of ignoring and attending emotional stimuli.

scientific article

Migraine polygenic risk score associates with efficacy of migraine-specific drugs

scientific article published on 24 October 2019

Modeling Linkage Disequilibrium Increases Accuracy of Polygenic Risk Scores

scientific article

Modeling Linkage Disequilibrium Increases Accuracy of Polygenic Risk Scores

Most genetic risk for autism resides with common variation ⬇️

scientific article

New data and an old puzzle: the negative association between schizophrenia and rheumatoid arthritis

scientific article

New susceptibility loci for severe COVID-19 by detailed GWAS analysis in European populations

scholarly article published 23 July 2021

No evidence for shared genetic basis of common variants in multiple sclerosis and amyotrophic lateral sclerosis

scientific article

Non-random mating, parent-of-origin, and maternal-fetal incompatibility effects in schizophrenia

scientific article

Novel genetic risk markers for ulcerative colitis in the IL2/IL21 region are in epistasis with IL23R and suggest a common genetic background for ulcerative colitis and celiac disease

scientific article

Nucleus accumbens connectivity at rest is associated with alcohol consumption in young male adults

scientific article published on 18 November 2019

PTPRD (protein tyrosine phosphatase receptor type delta) is associated with restless legs syndrome

scientific article published on 27 July 2008

Partitioning heritability by functional annotation using genome-wide association summary statistics

scientific article

Partitioning heritability of regulatory and cell-type-specific variants across 11 common diseases

scientific article

Pavlovian-To-Instrumental Transfer and Alcohol Consumption in Young Male Social Drinkers: Behavioral, Neural and Polygenic Correlates

scientific article published on 08 August 2019

Polygenic Risk Score, Parental Socioeconomic Status, Family History of Psychiatric Disorders, and the Risk for Schizophrenia: A Danish Population-Based Study and Meta-analysis.

scientific article published on July 2015

Polygenic dissection of diagnosis and clinical dimensions of bipolar disorder and schizophrenia

scientific article

Polygenic risk for schizophrenia and schizotypal traits in non-clinical subjects

scientific article published on 06 August 2020

Polygenic transmission and complex neuro developmental network for attention deficit hyperactivity disorder: genome-wide association study of both common and rare variants ⬇️

scientific article

Polygenic transmission disequilibrium confirms that common and rare variation act additively to create risk for autism spectrum disorders

article

Polygenic transmission disequilibrium confirms that common and rare variation act additively to create risk for autism spectrum disorders.

scientific article published on 15 May 2017

Polymorphisms in the GAD2 gene-region are associated with susceptibility for unipolar depression and with a risk factor for anxiety disorders

scientific article published in December 2009

Polymorphisms in the angiotensin-converting enzyme gene region predict coping styles in healthy adults and depressed patients

scientific article published on January 2009

Polymorphisms in the drug transporter gene ABCB1 predict antidepressant treatment response in depression

scientific article

Publisher Correction: Common schizophrenia alleles are enriched in mutation-intolerant genes and in regions under strong background selection

scientific article published on 01 July 2019

Quantifying between-cohort and between-sex genetic heterogeneity in major depressive disorder

scientific article published on 01 February 2019

RICOPILI: Rapid Imputation for COnsortias PIpeLIne

scientific article published on 01 February 2020

Rare complete knockouts in humans: population distribution and significant role in autism spectrum disorders

scientific article published on January 2013

Rare copy number variation in treatment-resistant major depressive disorder

scientific article

Rare, low-frequency, and common variants in the protein-coding sequence of biological candidate genes from GWASs contribute to risk of rheumatoid arthritis

scientific article published on 20 December 2012

Reliability in adolescent fMRI within two years - a comparison of three tasks

scientific article published on 23 May 2017

Resistance to antidepressant treatment is associated with polymorphisms in the leptin gene, decreased leptin mRNA expression, and decreased leptin serum levels

scientific article

Response to 'Predicting the diagnosis of autism spectrum disorder using gene pathway analysis'.

scientific article published on 22 October 2013

Reward processing and intertemporal decision making in adults and adolescents: the role of impulsivity and decision consistency

scientific article published on 25 August 2012

Runs of homozygosity implicate autozygosity as a schizophrenia risk factor

scientific article

Schizophrenia genetic variants are not associated with intelligence

scientific article published on 15 February 2013

Sequencing chromosomal abnormalities reveals neurodevelopmental loci that confer risk across diagnostic boundaries.

scientific article published on 19 April 2012

Seven new loci associated with age-related macular degeneration

scientific article

Shared Genetic Risk Factors of Intracranial, Abdominal, and Thoracic Aneurysms

scientific article published on 14 July 2016

Shared genetic etiology between alcohol dependence and major depressive disorder.

scientific article published in August 2018

Shared genetic risk between eating disorder- and substance-use-related phenotypes: Evidence from genome-wide association studies

scientific article published on 16 February 2020

Significant Locus and Metabolic Genetic Correlations Revealed in Genome-Wide Association Study of Anorexia Nervosa

scientific article published on 12 May 2017

Specific glial functions contribute to schizophrenia susceptibility

scientific article

TMEM132D, a new candidate for anxiety phenotypes: evidence from human and mouse studies

scientific article published on 6 April 2010

Temporal delay discounting in acutely ill and weight-recovered patients with anorexia nervosa

scientific article published on 12 January 2015

The GABA transporter 1 (SLC6A1): a novel candidate gene for anxiety disorders

scientific article published on 08 July 2008

The IMAGEN study: a decade of imaging genetics in adolescents

scientific article published on 29 June 2020

The association between lower educational attainment and depression owing to shared genetic effects? Results in ~25,000 subjects

scientific article published in June 2015

The genetic association between personality and major depression or bipolar disorder. A polygenic score analysis using genome-wide association data

scientific article

The major genetic determinants of HIV-1 control affect HLA class I peptide presentation

scientific article

The neuronal transporter gene SLC6A15 confers risk to major depression

scientific article

Theory of mind network activity is altered in subjects with familial liability for schizophrenia

scientific article

Variations in tryptophan hydroxylase 2 linked to decreased serotonergic activity are associated with elevated risk for metabolic syndrome in depression

scientific article published on 6 January 2009

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