List of works - Miriam Moffatt

A cross-platform analysis of 14,177 expression quantitative trait loci derived from lymphoblastoid cell lines

scientific article published on 23 January 2013

A genome-wide association study of atopic dermatitis identifies loci with overlapping effects on asthma and psoriasis

scientific article published on 25 July 2013

A large-scale, consortium-based genomewide association study of asthma

scientific article

A novel role for ciliary function in atopy: ADGRV1 and DNAH5 interactions

scientific article published on 16 September 2017

A polymorphism affecting MYB binding within the promoter of the PDCD4 gene is associated with severe asthma in children.

scientific article

Airway Microbiota in Severe Asthma and Relationship to Asthma Severity and Phenotypes

scientific article

Allele-specific transcription of the asthma-associated PHD finger protein 11 gene (PHF11) modulated by octamer-binding transcription factor 1 (Oct-1).

scientific article

An epigenome-wide association study of total serum immunoglobulin E concentration.

scientific article published on 18 February 2015

An integration of genome-wide association study and gene expression profiling to prioritize the discovery of novel susceptibility Loci for osteoporosis-related traits

scientific article

Chromosome 17q21 SNP and severe asthma.

scientific article

Corticosteroid suppression of antiviral immunity increases bacterial loads and mucus production in COPD exacerbations.

scientific article published on 8 June 2018

DNA methylation in childhood asthma: an epigenome-wide meta-analysis

scientific article published on 26 February 2018

DNA methylation within melatonin receptor 1A (MTNR1A) mediates paternally transmitted genetic variant effect on asthma plus rhinitis

scientific article published on 30 March 2016

Disordered microbial communities in asthmatic airways

scientific article

Dynamic and physical clustering of gene expression during epidermal barrier formation in differentiating keratinocytes

scientific article

Dysbiosis anticipating necrotizing enterocolitis in very premature infants

scientific article published on 23 October 2014

EGF receptor (EGFR) inhibition promotes a slow-twitch oxidative, over a fast-twitch, muscle phenotype

scientific article published on 25 June 2019

ENU mutagenesis as a tool for understanding lung development and disease.

scientific article published in August 2009

Erratum: Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution

scientific article published in November 2011

Estimating cell-type-specific DNA methylation effects in heterogeneous cellular populations

scientific article published on 22 December 2020

Exome-wide analysis of rare coding variation identifies novel associations with COPD and airflow limitation in MOCS3, IFIT3 and SERPINA12.

scientific article published on 25 February 2016

Fast and robust adjustment of cell mixtures in epigenome-wide association studies with SmartSVA

scientific article

Fraction of exhaled nitric oxide values in childhood are associated with 17q11.2-q12 and 17q12-q21 variants

scientific article

Functional analysis of a novel ENU-induced PHD finger 11 (Phf11) mouse mutant

scientific journal article

Gene expression in transformed lymphocytes reveals variation in endomembrane and HLA pathways modifying cystic fibrosis pulmonary phenotypes

scientific article

Genetic evidence of assortative mating in humans

article

Genetic studies of body mass index yield new insights for obesity biology

scientific article

Genetic variants regulating ORMDL3 expression contribute to the risk of childhood asthma

scientific article (publication date: 26 July 2007)

Genetics of complex airway disease

scientific article

Genome-wide association analysis identifies PDE4D as an asthma-susceptibility gene

scientific journal article

Genome-wide association studies in the genetics of asthma

scientific article published on January 2009

Genome-wide association study identifies loci influencing concentrations of liver enzymes in plasma

scientific article published on 16 October 2011

Genome-wide association study identifies multiple susceptibility loci for pulmonary fibrosis

scientific journal article

Genome-wide association study of lung function decline in adults with and without asthma

scientific article published on 16 March 2012

Genome-wide imputation study identifies novel HLA locus for pulmonary fibrosis and potential role for auto-immunity in fibrotic idiopathic interstitial pneumonia

scientific article

Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture

scientific journal article

Genome-wide scan on total serum IgE levels identifies FCER1A as novel susceptibility locus

scientific article

Improved detection of bifidobacteria with optimised 16S rRNA-gene based pyrosequencing

scientific article (publication date: 2012)

Imputation of KIR Types from SNP Variation Data

scientific article

In the Wrong Place at the Wrong Time: Microbial Misplacement and Acute Respiratory Distress Syndrome

scientific article published on 01 March 2020

Inhaled corticosteroid suppression of cathelicidin drives dysbiosis and bacterial infection in chronic obstructive pulmonary disease

scientific article published on 01 August 2019

Integrating pathway analysis and genetics of gene expression for genome-wide association study of basal cell carcinoma

scientific article published on 18 October 2011

Late-Onset Bloodstream Infection and Perturbed Maturation of the Gastrointestinal Microbiota in Premature Infants

scientific article published on 13 July 2015

Longitudinal development of the airway microbiota in infants with cystic fibrosis

article

Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution

scientific article

Meta-analysis of 20 genome-wide linkage studies evidenced new regions linked to asthma and atopy

scientific article

Neutrophilic inflammation in the respiratory mucosa predisposes to RSV infection

scientific article published on 01 October 2020

New genetic loci link adipose and insulin biology to body fat distribution

scientific article

Novel childhood asthma genes interact with in utero and early-life tobacco smoke exposure

scientific article published on 6 December 2013

Outgrowth of the bacterial airway microbiome after rhinovirus exacerbation of chronic obstructive pulmonary disease.

scientific article

PDE11A associations with asthma: results of a genome-wide association scan

scientific article

PLAUR polymorphisms and lung function in UK smokers

scientific article

Polymorphisms of PHF11 and DPP10 Are Associated with Asthma and Related Traits in a Chinese Population

article

Positional cloning of a novel gene influencing asthma from chromosome 2q14.

scientific article

Positional cloning of a quantitative trait locus on chromosome 13q14 that influences immunoglobulin E levels and asthma

scientific article

Pulmonary ORMDL3 is critical for induction of Alternaria-induced allergic airways disease.

scientific article

Reagent and laboratory contamination can critically impact sequence-based microbiome analyses

scientific article

Respiratory Viral Infection Alters the Gut Microbiota by Inducing Inappetence

scientific article published on 18 February 2020

Role of airway glucose in bacterial infections in patients with chronic obstructive pulmonary disease.

scientific article published on 13 December 2017

Sequencing the human microbiome in health and disease.

scientific article

Seventy-five genetic loci influencing the human red blood cell

scientific article published on 5 December 2012

The ORMDL3 Asthma Gene Regulates ICAM1 and has Multiple Effects on Cellular Inflammation

article

The genetics of atopic dermatitis

scientific article

The genetics of atopic dermatitis

scientific article published on 19 May 2006

The impact of persistent bacterial bronchitis on the pulmonary microbiome of children

scientific article published on 30 August 2017

The role of ALOX5AP, LTA4H and LTB4R polymorphisms in determining baseline lung function and COPD susceptibility in UK smokers.

scientific article

The role of bacteria in the pathogenesis and progression of idiopathic pulmonary fibrosis

scientific article

Upper airways microbiota in antibiotic-naïve wheezing and healthy infants from the tropics of rural Ecuador

scientific article

Variants of DENND1B associated with asthma in children

scientific article

Vitamin D levels and susceptibility to asthma, elevated immunoglobulin E levels, and atopic dermatitis: A Mendelian randomization study.

scientific article

eQTL mapping identifies insertion- and deletion-specific eQTLs in multiple tissues

scientific article published on 08 May 2015

iGWAS: Integrative Genome-Wide Association Studies of Genetic and Genomic Data for Disease Susceptibility Using Mediation Analysis

scientific article

List of works by Miriam Moffatt

A cross-platform analysis of 14,177 expression quantitative trait loci derived from lymphoblastoid cell lines

A genome-wide association study of atopic dermatitis identifies loci with overlapping effects on asthma and psoriasis

A large-scale, consortium-based genomewide association study of asthma

A novel role for ciliary function in atopy: ADGRV1 and DNAH5 interactions

A polymorphism affecting MYB binding within the promoter of the PDCD4 gene is associated with severe asthma in children.

Airway Microbiota in Severe Asthma and Relationship to Asthma Severity and Phenotypes

Allele-specific transcription of the asthma-associated PHD finger protein 11 gene (PHF11) modulated by octamer-binding transcription factor 1 (Oct-1).

An epigenome-wide association study of total serum immunoglobulin E concentration.

An integration of genome-wide association study and gene expression profiling to prioritize the discovery of novel susceptibility Loci for osteoporosis-related traits

Chromosome 17q21 SNP and severe asthma.

Corticosteroid suppression of antiviral immunity increases bacterial loads and mucus production in COPD exacerbations.

DNA methylation in childhood asthma: an epigenome-wide meta-analysis

DNA methylation within melatonin receptor 1A (MTNR1A) mediates paternally transmitted genetic variant effect on asthma plus rhinitis

Disordered microbial communities in asthmatic airways

Dynamic and physical clustering of gene expression during epidermal barrier formation in differentiating keratinocytes

Dysbiosis anticipating necrotizing enterocolitis in very premature infants

EGF receptor (EGFR) inhibition promotes a slow-twitch oxidative, over a fast-twitch, muscle phenotype

ENU mutagenesis as a tool for understanding lung development and disease.

Erratum: Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution

Estimating cell-type-specific DNA methylation effects in heterogeneous cellular populations

Exome-wide analysis of rare coding variation identifies novel associations with COPD and airflow limitation in MOCS3, IFIT3 and SERPINA12.

Fast and robust adjustment of cell mixtures in epigenome-wide association studies with SmartSVA

Fraction of exhaled nitric oxide values in childhood are associated with 17q11.2-q12 and 17q12-q21 variants

Functional analysis of a novel ENU-induced PHD finger 11 (Phf11) mouse mutant

Gene expression in transformed lymphocytes reveals variation in endomembrane and HLA pathways modifying cystic fibrosis pulmonary phenotypes

Genetic evidence of assortative mating in humans

Genetic studies of body mass index yield new insights for obesity biology

Genetic variants regulating ORMDL3 expression contribute to the risk of childhood asthma

Genetics of complex airway disease

Genome-wide association analysis identifies PDE4D as an asthma-susceptibility gene

Genome-wide association studies in the genetics of asthma

Genome-wide association study identifies loci influencing concentrations of liver enzymes in plasma

Genome-wide association study identifies multiple susceptibility loci for pulmonary fibrosis

Genome-wide association study of lung function decline in adults with and without asthma

Genome-wide imputation study identifies novel HLA locus for pulmonary fibrosis and potential role for auto-immunity in fibrotic idiopathic interstitial pneumonia

Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture

Genome-wide scan on total serum IgE levels identifies FCER1A as novel susceptibility locus

Improved detection of bifidobacteria with optimised 16S rRNA-gene based pyrosequencing

Imputation of KIR Types from SNP Variation Data

In the Wrong Place at the Wrong Time: Microbial Misplacement and Acute Respiratory Distress Syndrome

Inhaled corticosteroid suppression of cathelicidin drives dysbiosis and bacterial infection in chronic obstructive pulmonary disease

Integrating pathway analysis and genetics of gene expression for genome-wide association study of basal cell carcinoma

Late-Onset Bloodstream Infection and Perturbed Maturation of the Gastrointestinal Microbiota in Premature Infants

Longitudinal development of the airway microbiota in infants with cystic fibrosis

Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution

Meta-analysis of 20 genome-wide linkage studies evidenced new regions linked to asthma and atopy

Neutrophilic inflammation in the respiratory mucosa predisposes to RSV infection

New genetic loci link adipose and insulin biology to body fat distribution

Novel childhood asthma genes interact with in utero and early-life tobacco smoke exposure

Outgrowth of the bacterial airway microbiome after rhinovirus exacerbation of chronic obstructive pulmonary disease.

PDE11A associations with asthma: results of a genome-wide association scan

PLAUR polymorphisms and lung function in UK smokers

Polymorphisms of PHF11 and DPP10 Are Associated with Asthma and Related Traits in a Chinese Population

Positional cloning of a novel gene influencing asthma from chromosome 2q14.

Positional cloning of a quantitative trait locus on chromosome 13q14 that influences immunoglobulin E levels and asthma

Pulmonary ORMDL3 is critical for induction of Alternaria-induced allergic airways disease.

Reagent and laboratory contamination can critically impact sequence-based microbiome analyses

Respiratory Viral Infection Alters the Gut Microbiota by Inducing Inappetence

Role of airway glucose in bacterial infections in patients with chronic obstructive pulmonary disease.

Sequencing the human microbiome in health and disease.

Seventy-five genetic loci influencing the human red blood cell

The ORMDL3 Asthma Gene Regulates ICAM1 and has Multiple Effects on Cellular Inflammation

The genetics of atopic dermatitis

The genetics of atopic dermatitis

The impact of persistent bacterial bronchitis on the pulmonary microbiome of children

The role of ALOX5AP, LTA4H and LTB4R polymorphisms in determining baseline lung function and COPD susceptibility in UK smokers.

The role of bacteria in the pathogenesis and progression of idiopathic pulmonary fibrosis

Upper airways microbiota in antibiotic-naïve wheezing and healthy infants from the tropics of rural Ecuador

Variants of DENND1B associated with asthma in children

Vitamin D levels and susceptibility to asthma, elevated immunoglobulin E levels, and atopic dermatitis: A Mendelian randomization study.

eQTL mapping identifies insertion- and deletion-specific eQTLs in multiple tissues

iGWAS: Integrative Genome-Wide Association Studies of Genetic and Genomic Data for Disease Susceptibility Using Mediation Analysis