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List of works by Bruno Quesnel

A case of refractory anemia with 17p- syndrome following azathioprine treatment for heart transplantation.

scientific article published in April 2004

A fiber-modified adenoviral vector interacts with immunoevasion molecules of the B7 family at the surface of murine leukemia cells derived from dormant tumors

scientific journal article

A new case of therapy-related acute myeloid leukaemia with t(8;16)(p11;p13)

scientific article published on 01 March 1998

A new murine aggressive leukemic model

scientific article published on 01 April 1999

A subpopulation of malignant CD34+CD138+B7-H1+ plasma cells is present in multiple myeloma patients

scientific article

Abnormal cytogenetics and significant bone marrow plasmacytosis are predictive of early progression and short survival in patients with low tumor mass asymptomatic multiple myeloma

scientific article published on 01 December 2004

Absence of amplification of MDM2 gene, a regulator of p53 function, in myelodysplastic syndromes

scientific article published on 01 August 1993

Absence of rearrangement of the neurofibromatosis 1 (NF1) gene in myelodysplastic syndromes and acute myeloid leukemia

scientific article published on 01 May 1994

Accumulation of classical monocytes defines a subgroup of MDS that frequently evolves into CMML.

scientific article published on 13 June 2017

Activity of ladanein on leukemia cell lines and its occurrence in Marrubium vulgare.

scientific article published on 30 July 2009

Acute Myocarditis Induced by Hypomethylating Agents

Acute myeloid leukemia with translocation (8;21) or inversion (16) in elderly patients treated with conventional chemotherapy: a collaborative study of the French CBF-AML intergroup

scientific article published on 31 August 2009

Administration of alemtuzumab and G-CSF to adults with relapsed or refractory acute lymphoblastic leukemia: results of a phase II study.

scientific article published on 28 August 2013

Allogeneic bone marrow transplantation in patients with follicular lymphoma: a single center study

scientific article published on 01 August 2002

Alpha-defensins secreted by dysplastic granulocytes inhibit the differentiation of monocytes in chronic myelomonocytic leukemia.

scientific article published on 28 October 2009

An 18-case outbreak of drug-resistant Pseudomonas aeruginosa bacteriemia in hematology patients

scientific article published on 01 August 2006

Azacitidine in the treatment of therapy related myelodysplastic syndrome and acute myeloid leukemia (tMDS/AML): A report on 54 patients by the Groupe Francophone Des Myelodysplasies (GFM) ⬇️

scientific article published on March 15, 2013

Azacitidine in untreated acute myeloid leukemia: a report on 149 patients

scientific article published on 06 February 2014

B7-H3 protein expression in acute myeloid leukemia

scientific article published on 17 September 2015

Bromodomain inhibitor OTX015 in patients with acute leukaemia: a dose-escalation, phase 1 study

scientific article

CAR T-cells: A John von Neumann legacy?

scientific article published on 21 April 2018

CD38 in Hairy Cell Leukemia Is a Marker of Poor Prognosis and a New Target for Therapy.

scientific article published on 13 July 2015

CD9 in acute myeloid leukemia: Prognostic role and usefulness to target leukemic stem cells

scientific article published on 10 February 2019

CHOP alone compared with CHOP plus radiotherapy for localized aggressive lymphoma in elderly patients: a study by the Groupe d'Etude des Lymphomes de l'Adulte

scientific article published on 16 January 2007

Cancer vaccines and tumor dormancy: a long-term struggle between host antitumor immunity and persistent cancer cells?

scientific article published on December 2006

Characteristic repartition of monocyte subsets as a diagnostic signature of chronic myelomonocytic leukemia

scientific article published on 7 April 2015

Clinico-Biological Features and Clonal Hematopoiesis in Patients with Severe COVID-19

scientific article published on 21 July 2020

Comparison of high-dose cytarabine and timed-sequential chemotherapy as consolidation for younger adults with AML in first remission: the ALFA-9802 study

scientific article published on 20 June 2011

Comprehensive molecular landscape in patients older than 80 years old diagnosed with acute myeloid leukemia: a study of the French Hauts-de-France AML observatory

article

Copy-number analysis identified new prognostic marker in acute myeloid leukemia

scientific article

Cylin/CDK inhibitors of the 9p21 chromosomal region and hematological malignancies

scientific article published on 01 September 1998

Cytosine arabinoside induces costimulatory molecule expression in acute myeloid leukemia cells.

scientific article published on July 2004

Daily practice management of myelodysplastic syndromes in France: data from 907 patients in a one-week cross-sectional study by the Groupe Francophone des Myelodysplasies

scientific article

Deregulation and Targeting of TP53 Pathway in Multiple Myeloma

scientific article published on 01 January 2018

Detection of p53 mutations in hematological malignancies: comparison between immunocytochemistry and DNA analysis.

scientific article published in August 1994

Different prognostic values of p15(INK4b) and p16(INK4a) gene methylations in multiple myeloma

scientific article published on 01 April 2003

Disease escape with the selective loss of the Philadelphia chromosome after tyrosine kinase inhibitor exposure in Ph-positive acute lymphoblastic leukemia

scientific article published on 27 January 2020

Dormant Tumor Cells Develop Cross-Resistance to Apoptosis Induced by CTLs or Imatinib Mesylate via Methylation of Suppressor of Cytokine Signaling 1

scientific article published on 01 May 2007

Dormant tumor cells as a therapeutic target?

scientific article published on April 2008

Effect of priming with granulocyte-macrophage colony-stimulating factor in younger adults with newly diagnosed acute myeloid leukemia: a trial by the Acute Leukemia French Association (ALFA) Group.

scientific article

Effectiveness and tolerance of low to very low dose thalidomide in low-risk myelodysplastic syndromes.

scientific article published on 21 July 2008

Efficacy of autologous stem cell transplantation in mantle cell lymphoma: a 3-year follow-up study

scientific article published on 01 February 2000

Efficient generation of antileukemic autologous T cells by short-term culture and gamma-irradiation of myeloid leukemic cells.

scientific article published on 20 April 2004

Exploiting mitochondrial dysfunction for effective elimination of imatinib-resistant leukemic cells

scientific article

Extramedullary relapse in acute promyelocytic leukemia treated with all-trans retinoic acid and chemotherapy.

scientific article published in January 2006

Familial myeloid malignancies with germline TET2 mutation

scientific article published on 11 December 2019

Flow Cytometry to Estimate Leukemia Stem Cells in Primary Acute Myeloid Leukemia and in Patient-derived-xenografts, at Diagnosis and Follow Up

scientific article published on 26 March 2018

GILZ inhibits the mTORC2/AKT pathway in BCR-ABL(+) cells.

scientific article published in August 2011

GILZ overexpression attenuates endoplasmic reticulum stress-mediated cell death via the activation of mitochondrial oxidative phosphorylation

scientific article published on 11 July 2016

Gene transfer of CD154 and IL12 cDNA induces an anti-leukemic immunity in a murine model of acute leukemia.

scientific article published in September 2002

Gene transfer of GM-CSF, CD80 and CD154 cDNA enhances survival in a murine model of acute leukemia with persistence of a minimal residual disease.

scientific article published in August 2000

Genome wide SNP array identified multiple mechanisms of genetic changes in Waldenstrom macroglobulinemia.

scientific article

Genomic Landscape of CXCR4 Mutations in Waldenström Macroglobulinemia

scientific article published on 21 October 2015

Genomic characterization of Imatinib resistance in CD34+ cell populations from chronic myeloid leukaemia patients

scientific article published on 03 August 2010

Glucose metabolism and NRF2 coordinate the antioxidant response in melanoma resistant to MAPK inhibitors

scientific article published on 27 February 2018

Haemodynamically proven pulmonary hypertension in a patient with GATA2 deficiency-associated pulmonary alveolar proteinosis and fibrosis

scientific article published on 11 May 2017

Haemostatic and proteolytic markers in acute non lymphoid leukemia: a source of multiple informations

scientific article published on 01 January 1991

High occurrence of JAK2 V617 mutation in refractory anemia with ringed sideroblasts associated with marked thrombocytosis

scientific article published on 21 September 2006

IDH1/2 but not DNMT3A mutations are suitable targets for minimal residual disease monitoring in acute myeloid leukemia patients: a study by the Acute Leukemia French Association

scientific article published on 13 October 2015

Impact of TET2 mutations on response rate to azacitidine in myelodysplastic syndromes and low blast count acute myeloid leukemias

scientific article published on 15 April 2011

Impact of Wilms' tumor 1 expression on outcome of patients undergoing allogeneic stem cell transplantation for AML

scientific article published on 09 January 2017

In a model of tumor dormancy, long-term persistent leukemic cells have increased B7-H1 and B7.1 expression and resist CTL-mediated lysis.

scientific article published on 10 June 2004

In vivo expression and antitumor activity of p53 gene transfer with naked plasmid DNA in an ovarian cancer xenograft model in nude mice.

scientific article published on October 2006

Inactivation of the retinoblastoma gene appears to be very uncommon in myelodysplastic syndromes

scientific article published on 01 May 1994

Incidence and prognostic impact of c-Kit, FLT3, and Ras gene mutations in core binding factor acute myeloid leukemia (CBF-AML).

scientific article published in June 2006

Incidence and prognostic value of TET2 alterations in de novo acute myeloid leukemia achieving complete remission.

scientific article published on 20 May 2010

Increased gene transfer in acute myeloid leukemic cells by an adenovirus vector containing a modified fiber protein.

scientific article published on March 1999

Indoleamine 2,3-dioxygenase activity of acute myeloid leukemia cells can be measured from patients' sera by HPLC and is inducible by IFN-gamma.

scientific article

Induction of leukemia-specific CD8+ cytotoxic T cells with autologous myeloid leukemic cells maturated with a fiber-modified adenovirus encoding TNF-alpha

scientific article published on 20 January 2005

Infectious complications in adult acute myeloid leukemia: analysis of the Acute Leukemia French Association-9802 prospective multicenter clinical trial ⬇️

scientific article published on January 31, 2012

Inherited transmission of the CSF3R T618I mutational hotspot in familial chronic neutrophilic leukemia

scientific article published on 01 December 2019

Inhibiting the oncogenic translation program is an effective therapeutic strategy in multiple myeloma.

scientific article

Involvement of ORAI1/SOCE in Human AML Cell Lines and Primary Cells According to ABCB1 Activity, LSC Compartment and Potential Resistance to Ara-C Exposure

scientific article published on 16 May 2022

Involvement of a common progenitor cell in core binding factor acute myeloid leukaemia associated with mastocytosis

scientific article published on 04 August 2012

Isolation and characterization of two canine melanoma cell lines: new models for comparative oncology

scientific article published on 04 December 2018

Linezolid induces ring sideroblasts

scientific article published on November 2013

Long-term follow up of invasive aspergillosis in allogeneic stem cell transplantation recipients and leukemia patients: Differences in risk factors and outcomes

scientific article

Long-term follow-up of European APL 2000 trial, evaluating the role of cytarabine combined with ATRA and Daunorubicin in the treatment of nonelderly APL patients

scientific article

Long-term outcome of higher-risk MDS patients treated with azacitidine: an update of the GFM compassionate program cohort ⬇️

scientific article published on June 21, 2012

Luspatercept in Patients with Lower-Risk Myelodysplastic Syndromes

scientific article published on 01 January 2020

MDM2 gene amplification in human breast cancer

scientific article published on 01 January 1994

MYD88 L265P mutation contributes to the diagnosis of Bing Neel syndrome

scientific article

MYD88 L265P mutation in Waldenstrom macroglobulinemia.

scientific article published on 26 March 2013

Melanoma dormancy in a mouse model is linked to GILZ/FOXO3A-dependent quiescence of disseminated stem-like cells.

scientific article published on 28 July 2016

Metabolic rewiring in cancer cells overexpressing the glucocorticoid-induced leucine zipper protein (GILZ): Activation of mitochondrial oxidative phosphorylation and sensitization to oxidative cell death induced by mitochondrial targeted drugs

scientific article published on March 2017

Metabolites of tryptophan catabolism are elevated in sera of patients with myelodysplastic syndromes and inhibit hematopoietic progenitor amplification

scientific article published on 28 February 2013

Methylation and myelodysplastic syndromes: when and where?

scientific article published on 16 June 2006

Methylation of the p15(INK4b) gene in myelodysplastic syndromes is frequent and acquired during disease progression

scientific article published on 01 April 1998

Methyltransferases in myelodysplastic syndromes: guilty or not guilty?

scientific article published on 13 December 2008

Mitochondrial oxidative phosphorylation controls cancer cell's life and death decisions upon exposure to MAPK inhibitors

scientific article published on 29 February 2016

Molecular characterization of the idiopathic hypereosinophilic syndrome (HES) in 35 French patients with normal conventional cytogenetics.

scientific article

Molecular prognostic factors in acute myeloid leukemia receiving first-line therapy with azacitidine

scientific article published on 19 November 2015

Monocyte chemoattractant protein 1 (MCP-1/CCL2) contributes to thymus atrophy in acute myeloid leukemia.

scientific article published on 4 December 2014

Mutation allele burden remains unchanged in chronic myelomonocytic leukaemia responding to hypomethylating agents

scientific article published on 24 February 2016

NK cells that are activated by CXCL10 can kill dormant tumor cells that resist CTL-mediated lysis and can express B7-H1 that stimulates T cells.

scientific article

Outcome of High-Risk Myelodysplastic Syndrome After Azacitidine Treatment Failure ⬇️

scientific article published on July 25, 2011

Outcome of acute myeloid leukaemia following myelodysplastic syndrome after azacitidine treatment failure.

scientific article published on 06 March 2012

Outcome of older patients with acute myeloid leukemia in first relapse

scientific article published on 7 August 2013

Outcome of patients with high risk Myelodysplastic Syndrome (MDS) and advanced Chronic Myelomonocytic Leukemia (CMML) treated with decitabine after azacitidine failure.

scientific article published on 16 February 2015

Outcomes in RBC transfusion-dependent patients with Low-/Intermediate-1-risk myelodysplastic syndromes with isolated deletion 5q treated with lenalidomide: a subset analysis from the MDS-004 study

scientific article

Over-expression of the MDM2 gene is found in some cases of haematological malignancies.

scientific article published in October 1994

PD-1/PD-L1 binding studies using microscale thermophoresis

scientific article published on 15 December 2017

Pathologic and clinical features of 77 Hodgkin's lymphoma patients treated in a lymphoma protocol (LNH87): a GELA study.

scientific article

Phase II study of 3-hour infusion of high dose paclitaxel in refractory and relapsed aggressive non-Hodgkin's lymphomas. Groupe d'Etude des Lymphomes de l'Adulte.

scientific article

Primary central nervous system lymphoma in immunocompetent adults: poor results mainly associated with high treatment related toxicities.

scientific article published in September 2002

Prognostic factors for response and overall survival in 282 patients with higher-risk myelodysplastic syndromes treated with azacitidine.

scientific article published on 12 October 2010

Quantification of EVI1 transcript levels in acute myeloid leukemia by RT-qPCR analysis: A study by the ALFA Group

scientific article published on 9 October 2015

RIP3 is downregulated in human myeloid leukemia cells and modulates apoptosis and caspase-mediated p65/RelA cleavage

scientific article published on 21 August 2014

Rare occurrence of mutations of the FLR exon of the neurofibromatosis 1 (NF1) gene in myelodysplastic syndromes (MDS) and acute myeloid leukemia (AML)

scientific article published on 01 July 1993

Relationship between p53 gene mutations and multidrug resistance (mdr1) gene expression in myelodysplastic syndromes

scientific article published on 01 November 1993

Role of IRF4 in resistance to immunomodulatory (IMid) compounds® in Waldenström's macroglobulinemia.

scientific article published on 4 December 2017

SOCS-1 gene methylation is frequent but does not appear to have prognostic value in patients with multiple myeloma

article

Shortened first-line high-dose chemotherapy for patients with poor-prognosis aggressive lymphoma

scientific article

Sub-clonal analysis of the murine C1498 acute myeloid leukaemia cell line reveals genomic and immunogenic diversity.

scientific article published on 10 October 2017

Successful treatment of imatinib-resistant acute megakaryoblastic leukemia with e6a2 BCR/ABL: use of dasatinib and reduced-conditioning stem-cell transplantation

scientific article published on 07 June 2007

Successful treatment of juvenile rheumatoid arthritis associated haemophagocytic syndrome by cyclosporin A with transient exacerbation by conventional-dose G-CSF

scientific article published on 01 May 1997

Superior long-term outcome with idarubicin compared with high-dose daunorubicin in patients with acute myeloid leukemia age 50 years and older

scientific article

Synthesis and biological evaluation of phenstatin metabolites

scientific article published on 27 August 2011

Systemic injection of GM-CSF increases survival in a murine model of acute leukemia

scientific article published on 01 February 2002

TET2 gene mutation is a frequent and adverse event in chronic myelomonocytic leukemia

scientific article published on October 2009

TET2 mutation is an independent favorable prognostic factor in myelodysplastic syndromes (MDSs).

scientific article

TP53 mutation and its prognostic significance in Waldenstrom's Macroglobulinemia

scientific article

TPA stimulation culture for improved detection of t(11;14)(q13;q32) in mantle cell lymphoma

scientific article

TRPC3 shapes the ER-mitochondria Ca<sup>2+</sup> transfer characterizing tumour-promoting senescence

scientific article published on 17 February 2022

Targeting MYC in multiple myeloma

scientific article published on 22 February 2018

Tetraspanin CD81 is an adverse prognostic marker in acute myeloid leukemia.

scientific article published on 22 August 2016

The PI3K/AKT signaling pathway controls the quiescence of the low-Rhodamine123-retention cell compartment enriched for melanoma stem cell activity.

scientific article published on April 2013

The retinoblastoma gene (RB-1) status in multiple myeloma: a report on 35 cases.

scientific article published in August 1995

The revised IPSS is a powerful tool to evaluate the outcome of MDS patients treated with azacitidine: the GFM experience

scientific article published on 01 December 2012

Tissue factor pathway inhibitor-2 gene methylation is associated with low expression in carotid atherosclerotic plaques

scientific article published on 19 October 2008

Transduction of bone marrow cells by the AdZ.F(pK7) modified adenovirus demonstrates preferential gene transfer in myeloma cells.

scientific article published in November 1999

Treatment of progression of Philadelphia-negative myeloproliferative neoplasms to myelodysplastic syndrome or acute myeloid leukemia by azacitidine: a report on 54 cases on the behalf of the Groupe Francophone des Myelodysplasies (GFM).

scientific article published on 27 July 2010

Tumor dormancy and immunoescape.

scientific article published on July 2008

Tumor dormancy: long-term survival in a hostile environment

scientific article published on January 1, 2013

[Congenital asplenia, a differential diagnosis of essential thrombocythemia]

scientific article published on 01 November 1993

[Cytogenetics of malignant lymphomas in the year 2000]

scientific article published on 01 January 2000

[Inhibitors of cyclins/CDK of the 9p21 chromosomal region and malignant hemopathies]

scientific article published on 01 September 1998

[Residual disease: the hematologist's point of view]

scientific article published on 01 June 2001

[Tumor dormancy: is adaptative immunity a key player?]

scientific article published on 01 June 2008

gamma-ray irradiation induces B7.1 expression in myeloid leukaemic cells.

scientific article

p16 gene homozygous deletions in acute lymphoblastic leukemia

scientific article published on 01 February 1995

p16(INK4a) and p15(INK4b) gene methylations in plasma cells from monoclonal gammopathy of undetermined significance

scientific article published on 01 July 2001

p16(INK4a) immunocytochemical analysis is an independent prognostic factor in childhood acute lymphoblastic leukemia

scientific article published on 01 April 2002

p16ink4a gene and hematological malignancies.

scientific article published on June 1996

p53 mutations are associated with resistance to chemotherapy and short survival in hematologic malignancies

scientific article published on 01 November 1994

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