List of works by Bastian Opitz

A semi-synthetic glycoconjugate vaccine candidate for carbapenem-resistant Klebsiella pneumoniae

scientific article published on 16 August 2017

Adhesion of Moraxella catarrhalis to human bronchial epithelium characterized by a novel fluorescence-based assay

scientific article

Adjuvant immunotherapies as a novel approach to bacterial infections

scientific article published on April 2013

Beta-PIX and Rac1 GTPase mediate trafficking and negative regulation of NOD2.

scientific article

Differential requirement for the activation of the inflammasome for processing and release of IL-1beta in monocytes and macrophages

scientific article published on 22 December 2008

Dissection of a type I interferon pathway in controlling bacterial intracellular infection in mice

scientific article published on 24 August 2011

Essential role of mitochondrial antiviral signaling, IFN regulatory factor (IRF)3, and IRF7 in Chlamydophila pneumoniae-mediated IFN-beta response and control of bacterial replication in human endothelial cells

scientific article published on 12 February 2010

Extra- and intracellular innate immune recognition in endothelial cells.

scientific article published in August 2007

Histone acetylation and flagellin are essential for Legionella pneumophila-induced cytokine expression.

scientific article

IFNbeta induction by influenza A virus is mediated by RIG-I which is regulated by the viral NS1 protein

scientific article published on 28 November 2006

IFNbeta responses induced by intracellular bacteria or cytosolic DNA in different human cells do not require ZBP1 (DLM-1/DAI).

scientific article published on 2 September 2008

IFNs Modify the Proteome of Legionella-Containing Vacuoles and Restrict Infection Via IRG1-Derived Itaconic Acid

scientific article

Increasing the inspiratory time and I:E ratio during mechanical ventilation aggravates ventilator-induced lung injury in mice

scientific article

Inflammasome Deficiency Makes Pro-resolving Lipid Mediators Great Again

scientific article published on September 2017

Inflammasomes in Pneumococcal Infection: Innate Immune Sensing and Bacterial Evasion Strategies

scientific article

Innate immune recognition and inflammasome activation in listeria monocytogenes infection

scientific article

Innate immune recognition in infectious and noninfectious diseases of the lung

scientific article published on 18 February 2010

Intracellular bacteria differentially regulated endothelial cytokine release by MAPK-dependent histone modification

scientific article published in September 2005

Juvenile megaesophagus in PKCα-deficient mice is associated with an increase in the segment of the distal esophagus lined by smooth muscle cells

scientific article published on 4 May 2014

Legionella pneumophila glucosyltransferase inhibits host elongation factor 1A.

scholarly article

Legionella pneumophila induces IFNbeta in lung epithelial cells via IPS-1 and IRF3, which also control bacterial replication

scientific article

Legionella pneumophila induces human beta defensin-3 in pulmonary cells.

scientific article published on 8 July 2010

Legionella pneumophila-induced PKCalpha-, MAPK-, and NF-kappaB-dependent COX-2 expression in human lung epithelium.

scientific article published on 29 September 2006

Listeria monocytogenes activated p38 MAPK and induced IL-8 secretion in a nucleotide-binding oligomerization domain 1-dependent manner in endothelial cells

scientific article published in January 2006

Listeria monocytogenes induced Rac1-dependent signal transduction in endothelial cells

scientific article

Listeria monocytogenes-infected human peripheral blood mononuclear cells produce IL-1beta, depending on listeriolysin O and NLRP3.

scientific article

Lung epithelium as a sentinel and effector system in pneumonia--molecular mechanisms of pathogen recognition and signal transduction

scientific article published on 8 July 2006

Moraxella catarrhalis induces inflammatory response of bronchial epithelial cells via MAPK and NF-kappaB activation and histone deacetylase activity reduction

scientific article published on 6 January 2006

Moraxella catarrhalis is internalized in respiratory epithelial cells by a trigger-like mechanism and initiates a TLR2- and partly NOD1-dependent inflammatory immune response

scientific article published on 18 October 2006

NAIP and Ipaf control Legionella pneumophila replication in human cells.

scientific article

NLRP3 protects alveolar barrier integrity by an inflammasome-independent increase of epithelial cell adherence.

scientific article published on August 2016

NOD-Like Receptors in Lung Diseases

scientific article

Nod1-mediated endothelial cell activation by Chlamydophila pneumoniae

scientific article

Nucleotide oligomerization domain 1 ligation suppressed murine allergen-specific T-cell proliferation and airway hyperresponsiveness

scientific article published on May 2014

Nucleotide-binding oligomerization domain proteins are innate immune receptors for internalized Streptococcus pneumoniae

scientific article published on 23 June 2004

PKCα Deficiency in Mice Is Associated with Pulmonary Vascular Hyperresponsiveness to Thromboxane A2 and Increased Thromboxane Receptor Expression

scientific article

Pneumococci induced TLR- and Rac1-dependent NF-kappaB-recruitment to the IL-8 promoter in lung epithelial cells

scientific article published on 18 November 2005

Population analysis of Legionella pneumophila reveals a basis for resistance to complement-mediated killing

scientific article published on 09 December 2021

Rac1 regulates the NLRP3 inflammasome which mediates IL-1beta production in Chlamydophila pneumoniae infected human mononuclear cells

scientific article

Recognition of Streptococcus pneumoniae by the innate immune system.

scientific article published on 08 February 2012

Serotype 1 and 8 Pneumococci Evade Sensing by Inflammasomes in Human Lung Tissue

scientific article published on 28 August 2015

Simvastatin reduces Chlamydophila pneumoniae-mediated histone modifications and gene expression in cultured human endothelial cells

scientific article published on 28 February 2008

Spectrum of pathogen- and model-specific histopathologies in mouse models of acute pneumonia

scientific article

Statins control oxidized LDL-mediated histone modifications and gene expression in cultured human endothelial cells.

scientific article published on 2 January 2009

Streptococcus pneumoniae induced c-Jun-N-terminal kinase- and AP-1 -dependent IL-8 release by lung epithelial BEAS-2B cells

scientific article published on 12 July 2006

Streptococcus pneumoniae induced p38 MAPK- and NF-kappaB-dependent COX-2 expression in human lung epithelium

scientific article

Streptococcus pneumoniae-induced p38 MAPK-dependent phosphorylation of RelA at the interleukin-8 promotor

scientific article published on 13 October 2004

TLR2- and nucleotide-binding oligomerization domain 2-dependent Krüppel-like factor 2 expression downregulates NF-kappa B-related gene expression.

scientific article

The C-type lectin receptor Mincle binds to Streptococcus pneumoniae but plays a limited role in the anti-pneumococcal innate immune response

scientific article

The Common R71H-G230A-R293Q Human TMEM173 Is a Null Allele

scientific article published on 7 December 2016

The UspA1 protein of Moraxella catarrhalis induces CEACAM-1-dependent apoptosis in alveolar epithelial cells

scientific article published on 26 April 2007

The common HAQ STING variant impairs cGAS-dependent antibacterial responses and is associated with susceptibility to Legionnaires' disease in humans.

scientific article published on 3 January 2018

Vitamin D receptor binds to the ε germline gene promoter and exhibits transrepressive activity

scientific article published on November 2010

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