List of works - Patrick A Eyers

A new consensus for evaluating CDKL5/STK9-dependent signalling mechanisms

scientific article published on 30 October 2018

A redox-active switch in fructosamine-3-kinases expands the regulatory repertoire of the protein kinase superfamily

scientific article published on 07 July 2020

A single sulfatase is required to access colonic mucin by a gut bacterium

scientific article published on 06 October 2021

Aurora A regulation by reversible cysteine oxidation reveals evolutionarily conserved redox control of Ser/Thr protein kinase activity

scientific article published on 07 July 2020

Cataloguing the dead: breathing new life into pseudokinase research

scientific article published on 13 February 2020

Covalent inhibitors of EGFR family protein kinases induce degradation of human Tribbles 2 (TRIB2) pseudokinase in cancer cells.

scientific article published on 25 September 2018

Emerging concepts in pseudoenzyme classification, evolution, and signaling

scientific article published on 13 August 2019

Evaluation of Parameters for Confident Phosphorylation Site Localization Using an Orbitrap Fusion Tribrid Mass Spectrometer

scientific article

Exploring the Conformational Landscape and Stability of Aurora A Using Ion-Mobility Mass Spectrometry and Molecular Modeling

scientific article published on 31 January 2022

Extensive non-canonical phosphorylation in human cells revealed using strong-anion exchange-mediated phosphoproteomics

Human TRIB2 Oscillates during the Cell Cycle and Promotes Ubiquitination and Degradation of CDC25C

scientific article

Kinome-wide transcriptional profiling of uveal melanoma reveals new vulnerabilities to targeted therapeutics.

scientific article published on 3 October 2017

Local protein kinase A action proceeds through intact holoenzymes.

scientific article published in June 2017

New tools for carbohydrate sulfation analysis: heparan sulfate 2--sulfotransferase (HS2ST) is a target for small-molecule protein kinase inhibitors

article

New tools for evaluating protein tyrosine sulfation: tyrosylprotein sulfotransferases (TPSTs) are novel targets for RAF protein kinase inhibitors

article

Plk4 and Aurora A cooperate in the initiation of acentriolar spindle assembly in mammalian oocytes

scientific article published on 28 September 2017

Profiling the Human Phosphoproteome to Estimate the True Extent of Protein Phosphorylation

scientific article published on 09 May 2022

Strong anion exchange-mediated phosphoproteomics reveals extensive human non-canonical phosphorylation

scientific article published on 21 August 2019

The hVps34-SGK3 pathway alleviates sustained PI3K/Akt inhibition by stimulating mTORC1 and tumour growth

scientific article published on August 2016

Towards 20,20-difluorinated bryostatin: synthesis and biological evaluation of C17,C27-fragments

scientific article published on 01 February 2019

Tracing the origin and evolution of pseudokinases across the tree of life

scientific article published on 23 April 2019

List of works by Patrick A Eyers