Search filters

List of works by Dale I Godfrey

A Molecular Basis for NKT Cell Recognition of CD1d-Self-Antigen

scientific article

A Molecular Basis for the Exquisite CD1d-Restricted Antigen Specificity and Functional Responses of Natural Killer T Cells

scientific article

A class of γδ T cell receptors recognize the underside of the antigen-presenting molecule MR1

scientific article published on 01 December 2019

A conserved human T cell population targets mycobacterial antigens presented by CD1b

scientific article

A critical role for natural killer T cells in immunosurveillance of methylcholanthrene-induced sarcomas

scientific article

A divergent transcriptional landscape underpins the development and functional branching of MAIT cells

scientific article published on 01 November 2019

A fresh look at tumor immunosurveillance and immunotherapy.

scientific article

A minimal binding footprint on CD1d-glycolipid is a basis for selection of the unique human NKT TCR.

scientific article published on 31 March 2008

A molecular basis underpinning the T cell receptor heterogeneity of mucosal-associated invariant T cells

scientific article

A natural killer T (NKT) cell developmental pathway iInvolving a thymus-dependent NK1.1(-)CD4(+) CD1d-dependent precursor stage

scientific article

A non-canonical function of Ezh2 preserves immune homeostasis.

scientific article published on 21 February 2017

A nonclassical non-Valpha14Jalpha18 CD1d-restricted (type II) NKT cell is sufficient for down-regulation of tumor immunosurveillance

scientific article

A semi-invariant Vα10+ T cell antigen receptor defines a population of natural killer T cells with distinct glycolipid antigen-recognition properties

scientific article

A structural basis for selection and cross-species reactivity of the semi-invariant NKT cell receptor in CD1d/glycolipid recognition.

scientific article

A three-stage intrathymic development pathway for the mucosal-associated invariant T cell lineage.

scientific article published on 26 September 2016

Activation of invariant NKT cells exacerbates experimental visceral leishmaniasis

scientific article

Adaptability of the semi-invariant natural killer T-cell receptor towards structurally diverse CD1d-restricted ligands

scientific article published on 08 October 2009

Adaptability of the semi-invariant natural killer T-cell receptor towards structurally diverse CD1d-restricted ligands

scientific article published on December 2009

Alpha-galactosylceramide: potential immunomodulatory activity and future application

scientific article published on January 2004

Alternative cross-priming through CCL17-CCR4-mediated attraction of CTLs toward NKT cell-licensed DCs.

scientific article published on 28 February 2010

An overview on the identification of MAIT cell antigens.

scientific article published on 14 April 2018

Antibody responses to glycolipid-borne carbohydrates require CD4+ T cells but not CD1 or NKT cells

Antibody responses to glycolipid-borne carbohydrates require CD4+ T cells but not CD1 or NKT cells

scientific article published on 01 February 2011

Antigen Challenge Inhibits Thymic Emigration

scientific article published on 3 April 2006

Antigen Specificity of Type I NKT Cells Is Governed by TCR β-Chain Diversity.

scientific article published on 30 September 2015

Antigen recognition by CD1d-restricted NKT T cell receptors.

scientific article

Antigen-induced tolerance by intrathymic modulation of self-recognizing inhibitory receptors

scientific article

Antigen-loaded MR1 tetramers define T cell receptor heterogeneity in mucosal-associated invariant T cells

scientific article

Are We Really on the Right TRAIL?

scientific article published on 01 January 2005

Atypical natural killer T-cell receptor recognition of CD1d-lipid antigens.

scientific article published on 15 February 2016

Augmenting Influenza-Specific T Cell Memory Generation with a Natural Killer T Cell-Dependent Glycolipid-Peptide Vaccine

scientific article published on 18 October 2017

BH3-only Bcl-2 family member Bim is required for apoptosis of autoreactive thymocytes

scientific article (publication date: 21 February 2002)

Beta-testing NKT cell self-reactivity

scientific article published on 16 November 2011

Butyrophilin 2A1 is essential for phosphoantigen reactivity by γδ T cells

scientific article published on 09 January 2020

CD1b Tetramers Identify T Cells that Recognize Natural and Synthetic Diacylated Sulfoglycolipids from Mycobacterium tuberculosis

scientific article published on 29 January 2018

CD1d antigen presentation: treats for NKT cells

CD1d protein structure determines species-selective antigenicity of isoglobotrihexosylceramide (iGb3) to invariant NKT cells

scientific article

CD1d-Restricted NKT Cells: An Interstrain Comparison

scientific article published in August 2001

CD1d-lipid antigen recognition by the γδ TCR

scientific article

CD1d-lipid-antigen recognition by the semi-invariant NKT T-cell receptor

scientific article

CD38 expression on mouse T cells: CD38 defines functionally distinct subsets of αβ TCR+CD4−CD8−thymocytes

scientific article published in 1995

CD3bright signals on γδ T cells identify IL-17A-producing Vγ6Vδ1+ T cells

scientific article published on 11 November 2014

CD4+CD25+ T regulatory cells suppress NK cell-mediated immunotherapy of cancer

scientific article published on February 2006

Chewing the fat on natural killer T cell development.

scientific article published on 25 September 2006

Combined NKT cell activation and influenza virus vaccination boosts memory CTL generation and protective immunity.

scientific article

Congenic Analysis of the NKT Cell Control Gene Nkt2 Implicates the Peroxisomal Protein Pxmp4

scientific article published on 19 August 2008

Control points in NKT-cell development

scientific article published on July 2007

Control points in early T-cell development

scientific article published on November 1993

Corrigendum: The burgeoning family of unconventional T cells

scientific article

Corrigendum: The burgeoning family of unconventional T cells

scholarly article published in Nature Immunology

Cutting Edge: IL-21 Is Not Essential for Th17 Differentiation or Experimental Autoimmune Encephalomyelitis

scientific article published on 19 May 2008

Cytometric and functional analyses of NK and NKT cell deficiencies in NOD mice

scientific article published in July 2001

DOCK8 is critical for the survival and function of NKT cells

scientific article published on 08 August 2013

DX5/CD49b-Positive T Cells Are Not Synonymous with CD1d-Dependent NKT Cells

scientific article published on 21 September 2005

Developing NKT cells need their (E) protein

scientific article published on 18 May 2010

Developing NKT cells need their calcium

scientific article published in March 2009

Development of mucosal-associated invariant T cells

article

Differential Recognition of CD1d-α-Galactosyl Ceramide by the Vβ8.2 and Vβ7 Semi-invariant NKT T Cell Receptors

scientific article

Differential antitumor immunity mediated by NKT cell subsets in vivo

scientific article

Differential requirement for the CD45 splicing regulator hnRNPLL for accumulation of NKT and conventional T cells

scientific article

Differential surface phenotype and context-dependent reactivity of functionally diverse NKT cells.

scientific article published on 5 March 2018

Differential tumor surveillance by natural killer (NK) and NKT cells.

scientific article

Directing traffic on the NKT-cell highway: a key role for ThPOK.

scientific article published in September 2010

Discordant regulation of granzyme H and granzyme B expression in human lymphocytes

scientific article published on 6 April 2004

Distinct CD1d docking strategies exhibited by diverse Type II NKT cell receptors

scientific article published on 20 November 2019

Distinct roles in NKT cell maturation and function for the different transcription factors in the classical NF-κB pathway

scientific article published on 10 August 2010

Diverse MR1-restricted T cells in mice and humans

scientific article published on 21 May 2019

Diverse cytokine production by NKT cell subsets and identification of an IL-17-producing CD4-NK1.1- NKT cell population

scholarly article

Diversity of T Cells Restricted by the MHC Class I-Related Molecule MR1 Facilitates Differential Antigen Recognition

scientific article

Drugs and drug-like molecules can modulate the function of mucosal-associated invariant T cells. ⬇️

scientific article published on 6 February 2017

Dual Modifications of α-Galactosylceramide Synergize to Promote Activation of Human Invariant Natural Killer T Cells and Stimulate Anti-tumor Immunity

scientific article published on 9 March 2018

Dual Modifications of α-Galactosylceramide Synergize to Promote Activation of Human Invariant Natural Killer T Cells and Stimulate Anti-tumor Immunity

scientific article published in July 2018

ER-MP12 antigen, a new cell surface marker on mouse bone marrow cells with thymus-repopulating ability: II. Thymus-homing ability and phenotypic characterization of ER-MP12-positive bone marrow cells

scientific article published in 1993

Effective functional maturation of invariant natural killer T cells is constrained by negative selection and T-cell antigen receptor affinity

scientific article published on 16 December 2013

Endogenous IL-21 restricts CD8+ T cell expansion and is not required for tumor immunity.

scientific article published on 13 November 2009

Enumeration, functional responses and cytotoxic capacity of MAIT cells in newly diagnosed and relapsed multiple myeloma

scientific article published on 7 March 2018

Ex-vivo analysis of human natural killer T cells demonstrates heterogeneity between tissues and within established CD4(+) and CD4(-) subsets.

scientific article published in April 2013

Ex-vivo α-Galactosylceramide activation of NKT cells in humans and macaques

scientific article published in August 2012

Expression of the glucocorticoid receptor from the 1A promoter correlates with T lymphocyte sensitivity to glucocorticoid-induced cell death

scientific article published in September 2004

Expression, purification and characterisation of recombinant Escherichia coli derived chicken interleukin-12.

scientific article published on 23 August 2008

Fighting infection with your MAITs

Five novel antigens illustrate shared phenotype between mouse thymic stromal cells, thymocytes, and peripheral lymphocytes

scientific article published on September 1, 1992

Flow cytometric analysis reveals unexpected shared antigens between histologically defined populations of thymic stromal cells

scientific article published in 1994

Flow cytometric study of T cell development in NOD mice reveals a deficiency in alphabetaTCR+CDR-CD8- thymocytes.

scientific article published in June 1997

Functional analysis of granzyme M and its role in immunity to infection

scientific article published in September 2005

GRKO mice express an aberrant dexamethasone-binding glucocorticoid receptor, but are profoundly glucocorticoid resistant

scientific article

Genetic Control of NKT Cell Numbers Maps to Major Diabetes and Lupus Loci

scientific article published on 5 September 2003

German Society for Immunology and Australasian Society for Immunology joint Workshop 3(rd) -4(th) December 2015 - Meeting report

scientific article published in February 2016

Glucocorticoid receptor deficient thymic and peripheral T cells develop normally in adult mice

scientific article published in December 2002

Glucocorticoid-mediated repression of T-cell receptor signalling is impaired in glucocorticoid receptor exon 2-disrupted mice

scientific article published on 12 November 2013

Glucocorticoids and the thymus: the view from the middle of the road

scientific article published in May 2001

Glycolipid Antigen Drives Rapid Expansion and Sustained Cytokine Production by NK T Cells

scientific article published on 6 October 2003

Glycolipid-peptide vaccination induces liver-resident memory CD8+ T cells that protect against rodent malaria

scientific article published on 01 June 2020

Going both ways: immune regulation via CD1d-dependent NKT cells

scientific article published in November 2004

Hobit and Blimp1 instruct a universal transcriptional program of tissue residency in lymphocytes

scientific journal article

Human Mucosal-Associated Invariant T Cells in Older Individuals Display Expanded TCRαβ Clonotypes with Potent Antimicrobial Responses

scientific article published on 27 January 2020

Human and Mouse Type I Natural Killer T Cell Antigen Receptors Exhibit Different Fine Specificities for CD1d-Antigen Complex

scientific article

Human autoreactive T cells recognize CD1b and phospholipids

scientific article

Human blood MAIT cell subsets defined using MR1 tetramers.

scientific article published on 13 February 2018

Humoral and circulating follicular helper T cell responses in recovered patients with COVID-19

scientific article published on 13 July 2020

IL-17-producing NKT cells depend exclusively on IL-7 for homeostasis and survival.

scientific article published on 22 January 2014

IL-21 is produced by NKT cells and modulates NKT cell activation and cytokine production

scientific article published in March 2007

IL-21 regulates germinal center B cell differentiation and proliferation through a B cell-intrinsic mechanism

scientific article

Identification of Bcl-6-dependent follicular helper NKT cells that provide cognate help for B cell responses

article

Identification of a Potent Microbial Lipid Antigen for Diverse NKT Cells.

scientific article published on 07 August 2015

Identification of phenotypically and functionally heterogeneous mouse mucosal-associated invariant T cells using MR1 tetramers

scientific article published on 22 June 2015

Immune characterization of an individual with an exceptionally high natural killer T cell frequency and her immediate family.

scientific article published on 22 January 2009

Immune recognition of phosphoantigen-butyrophilin molecular complexes by γδ T cells

scientific article published on 05 October 2020

In-vivo stimulation of macaque natural killer T cells with α-galactosylceramide.

scientific article published in September 2013

Induction of natural killer T cell-dependent alloreactivity by administration of granulocyte colony-stimulating factor after bone marrow transplantation

scientific article published on 29 March 2009

Induction of tumor-specific T cell memory by NK cell–mediated tumor rejection

scientific article published on 17 December 2001

Innate immune surveillance of spontaneous B cell lymphomas by natural killer cells and gammadelta T cells

scientific article

Integrated immune dynamics define correlates of COVID-19 severity and antibody responses

scientific article published on 05 February 2021

Intrathymic NKT cell development is blocked by the presence of alpha-galactosylceramide

scientific article published on July 2003

Intrathymic T cell development and selection proceeds normally in the absence of glucocorticoid receptor signaling

scientific article

Intrathymic glucocorticoid production and thymocyte survival: another piece in the puzzle

scientific article published in June 2005

Invariant NKT Cells in Hyperplastic Skin Induce a Local Immune Suppressive Environment by IFN- Production

scientific article published on 18 December 2009

Limited correlation between human thymus and blood NKT?cell content revealed by an ontogeny study of paired tissue samples

scientific article published on 01 May 2005

Linear ubiquitin chain assembly complex coordinates late thymic T-cell differentiation and regulatory T-cell homeostasis

scientific article published on 18 November 2016

Lipid and small-molecule display by CD1 and MR1.

scientific article published on 21 September 2015

Liver-Resident Memory CD8+ T Cells Form a Front-Line Defense against Malaria Liver-Stage Infection

scientific article published on 17 September 2016

Liver-Resident Memory CD8+ T Cells Form a Front-Line Defense against Malaria Liver-Stage Infection

scientific article published on 01 October 2019

Localization of Idd11 is not associated with thymus and nkt cell abnormalities in NOD mice

scientific article published in December 2005

Long-term retention of mature NK1.1+ NKT cells in the thymus

scientific article published in April 2006

Lymphotoxin controls alphaEbeta7-integrin expression by peripheral CD8+ T cells.

scientific article published in August 2001

MAIT and Vδ2 unconventional T cells are supported by a diverse intestinal microbiome and correlate with favorable patient outcome after allogeneic HCT

scientific article published in 2022

MAIT cells are depleted early but retain functional cytokine expression in HIV infection

scientific article published on 28 October 2014

MAIT cells contribute to protection against lethal influenza infection in vivo

scientific article published in Nature Communications

MAIT cells protect against pulmonary Legionella longbeachae infection ⬇️

scientific article published in Nature Communications

MAIT cells regulate NK cell-mediated tumor immunity

scientific article published on 06 August 2021

MR1 presents microbial vitamin B metabolites to MAIT cells

scientific article

Mucosal-associated invariant T-cell activation and accumulation after in vivo infection depends on microbial riboflavin synthesis and co-stimulatory signals.

scientific article published on 4 May 2016

NK cells and NKT cells collaborate in host protection from methylcholanthrene-induced fibrosarcoma.

scientific article published in April 2001

NKT TCR Recognition of CD1d- -C-Galactosylceramide

scientific article

NKT cell depletion in humans during early HIV infection

scientific article published on 29 April 2014

NKT cell development in the absence of the autoimmune regulator gene (Aire)

scientific article published in October 2008

NKT cell stimulation with glycolipid antigen in vivo: costimulation-dependent expansion, Bim-dependent contraction, and hyporesponsiveness to further antigenic challenge

scientific article published in September 2005

NKT cell-dependent leukemia eradication following stem cell mobilization with potent G-CSF analogs.

scientific article

NKT cells - conductors of tumor immunity?

scientific article

NKT cells and tumor immunity—a double-edged sword

scientific article published in December 2000

NKT cells are not critical for HSV-1 disease resolution

scientific article published on 07 November 2005

NKT cells are phenotypically and functionally diverse

scientific article published in November 1999

NKT cells join the war on Lyme disease

scientific article published in September 2006

NKT cells: facts, functions and fallacies.

scientific article

NKT cells: the smoking gun in fungal-induced asthma?

scientific article published in October 2013

NKT cells: what's in a name?

scientific article published in March 2004

NKT cells—an early warning system for HBV infection

scientific article published in July 2012

Natural Killer T cell obsession with self-antigens

scientific article published on 4 February 2013

Natural killer T cell defects in multiple myeloma and the impact of lenalidomide therapy

scientific article published in January 2014

Natural killer T cells are targets for human immunodeficiency virus infection

scientific article published in January 2003

Negative selection of semimature CD4(+)8(-)HSA+ thymocytes requires the BH3-only protein Bim but is independent of death receptor signaling

scientific article published on 26 April 2004

New ways to turn on NKT cells

scientific article

Nfil3Is a Glucocorticoid-Regulated Gene Required for Glucocorticoid-Induced Apoptosis in Male Murine T Cells

scientific article published in April 2013

No requirement for TRAIL in intrathymic negative selection

scientific article published on 11 January 2008

Normal thymocyte negative selection in TRAIL-deficient mice

scientific article

OMIP-021: Simultaneous quantification of human conventional and innate-like T-cell subsets

scientific article published on 22 April 2014

PTPN2 regulates T cell lineage commitment and αβ versus γδ specification.

scientific article published on 10 August 2017

Parallels and distinctions between T and NKT cell development in the thymus.

scientific article published on June 2004

Perforin-mediated suppression of B-cell lymphoma

scholarly article

Peripheral NK1.1- NKT Cells Are Mature and Functionally Distinct from Their Thymic Counterparts

scientific article published on 2 November 2007

Peripheral NKT cells in simian immunodeficiency virus-infected macaques

scientific article published on 03 December 2008

Raising the NKT cell family

scientific article published on 07 February 2010

Rapid loss of group 1 innate lymphoid cells during blood stage Plasmodium infection‡.

scientific article published on 12 January 2018

Recent thymic emigrants are distinct from most medullary thymocytes

scientific article published in August 1997

Recognition of CD1d-restricted antigens by natural killer T cells

scientific article

Recognition of CD1d-sulfatide mediated by a type II natural killer T cell antigen receptor

scientific article

Recognition of Vitamin B Precursors and Byproducts by Mucosal Associated Invariant T Cells

scientific article

Recognition of microbial and mammalian phospholipid antigens by NKT cells with diverse TCRs.

scientific article published on 10 January 2013

Recognition of β-linked self glycolipids mediated by natural killer T cell antigen receptors

scientific article

Regulation of antitumour immunity by CD1d-restricted NKT cells

scientific article published on June 2004

Regulatory iNKT cells lack expression of the transcription factor PLZF and control the homeostasis of T(reg) cells and macrophages in adipose tissue

scientific article published in December 2014

Retraction Note to: Retraction: Antigen-induced tolerance by intrathymic modulation of self-recognizing inhibitory receptors

scientific article published on 01 August 2006

Sequential activation of NKT cells and NK cells provides effective innate immunotherapy of cancer

scientific article

Sequential production of interferon-gamma by NK1.1+ T cells and natural killer cells is essential for the antimetastatic effect of alpha -galactosylceramide

scientific article published on 01 February 2002

Signalling through the MHC class II cytoplasmic domain is required for antigen presentation and induces B7 expression

scientific article published on November 19, 1992

Spontaneous onset and transplant models of the Vk*MYC mouse show immunological sequelae comparable to human multiple myeloma.

scientific article published on 06 September 2016

Strain-dependent differences in bone development, myeloid hyperplasia, morbidity and mortality in ptpn2-deficient mice.

scientific article

Stress-free T-cell development: glucocorticoids are not obligatory

scientific article

Structural determination of lipid antigens captured at the CD1d-T-cell receptor interface

scientific article published on 17 July 2017

Structural insight into MR1-mediated recognition of the mucosal associated invariant T cell receptor

scientific article

Suppressor of cytokine signaling-1 is a critical regulator of interleukin-7-dependent CD8+ T cell differentiation.

scientific article published in April 2003

Systemic NKT cell deficiency in NOD mice is not detected in peripheral blood: implications for human studies

scientific article published on 01 June 2004

T cell antigen receptor recognition of antigen-presenting molecules

scientific article published on 10 December 2014

T cell autoreactivity directed toward CD1c itself rather than toward carried self lipids.

scientific article published on 12 March 2018

T cell protein tyrosine phosphatase attenuates T cell signaling to maintain tolerance in mice

scientific article published in December 2011

T cell receptor CDR2 beta and CDR3 beta loops collaborate functionally to shape the iNKT cell repertoire

scientific article

T cell receptor reversed polarity recognition of a self-antigen major histocompatibility complex

scientific article published in November 2015

TCF-1 limits the formation of Tc17 cells via repression of the MAF-RORγt axis

scientific article published on 29 May 2019

TCR bias and affinity define two compartments of the CD1b-glycolipid-specific T Cell repertoire

scientific article

TCR-mediated activation promotes GITR upregulation in T cells and resistance to glucocorticoid-induced death

scientific article published on 19 July 2004

Taming pathogenic γδ T cells with vitamin A.

scientific article published on 5 July 2016

Temporal Regulation of Natural Killer T Cell Interferon Gamma Responses by β-Catenin-Dependent and -Independent Wnt Signaling

scientific article published on 16 March 2018

Testing the NKT cell hypothesis in lenalidomide-treated myelodysplastic syndrome patients.

scientific article published on 14 January 2010

The Elusive NKT Cell Antigen--Is the Search Over?

scientific article

The NF-κB1 transcription factor prevents the intrathymic development of CD8 T cells with memory properties

scientific article published on 29 November 2011

The biology and functional importance of MAIT cells

scientific article published on 12 August 2019

The burgeoning family of unconventional T cells

scientific article

The effect of antigen stimulation on the migration of mature T cells from the peripheral lymphoid tissues to the thymus

scientific article published on January 2001

The fidelity, occasional promiscuity, and versatility of T cell receptor recognition

scientific article published on March 2008

The glucocorticoid receptor 1A3 promoter correlates with high sensitivity to glucocorticoid-induced apoptosis in human lymphocytes

scientific article published on 22 July 2014

The influence of CD1d in postselection NKT cell maturation and homeostasis

scientific article published on September 2005

The molecular bases of δ/αβ T cell-mediated antigen recognition.

scientific article

The structural basis for autonomous dimerization of the pre-T-cell antigen receptor

scientific article published on 14 October 2010

The thymic microenvironment.

scientific article

Three day neonatal thymectomy selectively depletes NK1.1+ T cells

scientific article published in October 1998

Thymic T cell export is not influenced by the peripheral T cell pool.

scientific article published in November 1997

Thymic emigration: conveyor belts or lucky dips?

scientific article

Thymic regeneration: teaching an old immune system new tricks

scientific article

Total Synthesis of Mycobacterium tuberculosis Dideoxymycobactin-838 and Stereoisomers: Diverse CD1a-Restricted T Cells Display a Common Hierarchy of Lipopeptide Recognition.

scientific article published on 7 December 2016

Type I natural killer T cells suppress tumors caused by p53 loss in mice

scientific article published on 20 February 2009

Unconventional T Cell Targets for Cancer Immunotherapy

scientific article published in March 2018

V 2 natural killer T cell antigen receptor-mediated recognition of CD1d-glycolipid antigen

scientific article

Without peripheral interference, thymic deletion is mediated in a cohort of double-positive cells without classical activation

scientific article published on 21 January 2003

Working with NKT cells — pitfalls and practicalities [Curr. Opin. Immunol. 17 (2005) 448]

Working with NKT cells--pitfalls and practicalities

scientific article

ZBTB7B (Th-POK) regulates the development of IL-17-producing CD1d-restricted mouse NKT cells

scientific article published on 26 October 2012

alpha/beta-T cell receptor (TCR)+CD4-CD8- (NKT) thymocytes prevent insulin-dependent diabetes mellitus in nonobese diabetic (NOD)/Lt mice by the influence of interleukin (IL)-4 and/or IL-10.

scientific article

αβ T cell antigen receptor recognition of CD1a presenting self lipid ligands

scientific article

Paulina is supported by:

About Paulina

Help