List of works - Paul A. Davies

3B but which 3B and that's just one of the questions: the heterogeneity of human 5-HT3 receptors.

scientific article

A novel class of ligand-gated ion channel is activated by Zn2+

scientific article

Allosteric modulation of the 5-HT3 receptor ⬇️

scientific article published on February 20, 2011

Alternative transcripts of the GABA(A) receptor epsilon subunit in human and rat.

scientific article

Characterization of the effects of four HTR3B polymorphisms on human 5-HT3AB receptor expression and signalling.

scientific article

Compromising KCC2 transporter activity enhances the development of continuous seizure activity.

scientific article published on 21 April 2016

Compromising the phosphodependent regulation of the GABAAR β3 subunit reproduces the core phenotypes of autism spectrum disorders

scientific article published on 16 November 2015

Copper and protons directly activate the zinc-activated channel

scientific article published on 09 February 2016

Differential effects of serotonin and dopamine on human 5-HT3A receptor kinetics: interpretation within an allosteric kinetic model.

scientific article published on November 2007

Disrupted Cl(-) homeostasis contributes to reductions in the inhibitory efficacy of diazepam during hyperexcited states

scientific article published on 29 April 2013

Endogenous and synthetic neuroactive steroids evoke sustained increases in the efficacy of GABAergic inhibition via a protein kinase C-dependent mechanism.

scientific article published on 12 October 2016

Functional regulation of GABAA receptors in nervous system pathologies

scientific article

Identification of a Core Amino Acid Motif within the α Subunit of GABAARs that Promotes Inhibitory Synaptogenesis and Resilience to Seizures

scientific article published on 01 July 2019

Insensitivity to anaesthetic agents conferred by a class of GABA(A) receptor subunit

scientific article

KCC2 activity is critical in limiting the onset and severity of status epilepticus.

scientific article

Memory deficits induced by inflammation are regulated by α5-subunit-containing GABAA receptors.

scientific article

Metabotropic, but not allosteric, effects of neurosteroids on GABAergic inhibition depend on the phosphorylation of GABAA receptors

scientific article published on 25 June 2019

Modulation by general anaesthetics of rat GABAA receptors comprised of alpha 1 beta 3 and beta 3 subunits expressed in human embryonic kidney 293 cells.

scientific article

Modulation of human 5-hydroxytryptamine type 3AB receptors by volatile anesthetics and n-alcohols.

scientific article

Molecular properties important for inhaled anesthetic action on human 5-HT3A receptors.

scientific article

NMDA receptor activity downregulates KCC2 resulting in depolarizing GABAA receptor–mediated currents ⬇️

scientific article published on May 1, 2011

Neural circuits with long-distance axon tracts for determining functional connectivity.

scientific article published on 8 November 2013

Neuroactive Steroids Reverse Tonic Inhibitory Deficits in Fragile X Syndrome Mouse Model

scientific article published on 05 February 2019

Neurosteroids promote phosphorylation and membrane insertion of extrasynaptic GABAA receptors

scientific article

Phosphorylation of GABAA receptors influences receptor trafficking and neurosteroid actions

scientific article

Protein kinase C phosphorylation regulates membrane insertion of GABAA receptor subtypes that mediate tonic inhibition.

scientific article

Proteomic Characterization of Inhibitory Synapses Using a Novel pHluorin-tagged γ-Aminobutyric Acid Receptor, Type A (GABAA), α2 Subunit Knock-in Mouse

scientific article published on 04 April 2016

Regulating the Efficacy of Inhibition Through Trafficking of γ-Aminobutyric Acid Type A Receptors.

scientific article

The 5-HT3B subunit is a major determinant of serotonin-receptor function

scientific article

The residence time of GABA(A)Rs at inhibitory synapses is determined by direct binding of the receptor α1 subunit to gephyrin

scientific journal article

The small molecule CLP257 does not modify activity of the K+-Cl- co-transporter KCC2 but does potentiate GABAA receptor activity.

scientific article

List of works by Paul A. Davies

3B but which 3B and that's just one of the questions: the heterogeneity of human 5-HT3 receptors.

A novel class of ligand-gated ion channel is activated by Zn2+

Allosteric modulation of the 5-HT3 receptor ⬇️

Alternative transcripts of the GABA(A) receptor epsilon subunit in human and rat.

Characterization of the effects of four HTR3B polymorphisms on human 5-HT3AB receptor expression and signalling.

Compromising KCC2 transporter activity enhances the development of continuous seizure activity.

Compromising the phosphodependent regulation of the GABAAR β3 subunit reproduces the core phenotypes of autism spectrum disorders

Copper and protons directly activate the zinc-activated channel

Differential effects of serotonin and dopamine on human 5-HT3A receptor kinetics: interpretation within an allosteric kinetic model.

Disrupted Cl(-) homeostasis contributes to reductions in the inhibitory efficacy of diazepam during hyperexcited states

Endogenous and synthetic neuroactive steroids evoke sustained increases in the efficacy of GABAergic inhibition via a protein kinase C-dependent mechanism.

Functional regulation of GABAA receptors in nervous system pathologies

Identification of a Core Amino Acid Motif within the α Subunit of GABAARs that Promotes Inhibitory Synaptogenesis and Resilience to Seizures

Insensitivity to anaesthetic agents conferred by a class of GABA(A) receptor subunit

KCC2 activity is critical in limiting the onset and severity of status epilepticus.

Memory deficits induced by inflammation are regulated by α5-subunit-containing GABAA receptors.

Metabotropic, but not allosteric, effects of neurosteroids on GABAergic inhibition depend on the phosphorylation of GABAA receptors

Modulation by general anaesthetics of rat GABAA receptors comprised of alpha 1 beta 3 and beta 3 subunits expressed in human embryonic kidney 293 cells.

Modulation of human 5-hydroxytryptamine type 3AB receptors by volatile anesthetics and n-alcohols.

Molecular properties important for inhaled anesthetic action on human 5-HT3A receptors.

NMDA receptor activity downregulates KCC2 resulting in depolarizing GABAA receptor–mediated currents ⬇️

Neural circuits with long-distance axon tracts for determining functional connectivity.

Neuroactive Steroids Reverse Tonic Inhibitory Deficits in Fragile X Syndrome Mouse Model

Neurosteroids promote phosphorylation and membrane insertion of extrasynaptic GABAA receptors

Phosphorylation of GABAA receptors influences receptor trafficking and neurosteroid actions

Protein kinase C phosphorylation regulates membrane insertion of GABAA receptor subtypes that mediate tonic inhibition.

Proteomic Characterization of Inhibitory Synapses Using a Novel pHluorin-tagged γ-Aminobutyric Acid Receptor, Type A (GABAA), α2 Subunit Knock-in Mouse

Regulating the Efficacy of Inhibition Through Trafficking of γ-Aminobutyric Acid Type A Receptors.

The 5-HT3B subunit is a major determinant of serotonin-receptor function

The residence time of GABA(A)Rs at inhibitory synapses is determined by direct binding of the receptor α1 subunit to gephyrin

The small molecule CLP257 does not modify activity of the K+-Cl- co-transporter KCC2 but does potentiate GABAA receptor activity.