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List of works by Mathew Blurton-Jones

A microfluidic culture platform for CNS axonal injury, regeneration and transport

scientific article

Abeta inhibits the proteasome and enhances amyloid and tau accumulation

scientific article published on June 2007

Activation of cell cycle proteins in transgenic mice in response to neuronal loss but not amyloid-beta and tau pathology.

scientific article published in January 2009

An update on estrogen: higher cognitive function, receptor mapping, neurotrophic effects.

scientific article

Anatomical evidence for transsynaptic influences of estrogen on brain-derived neurotrophic factor expression.

scientific article published in January 2004

BDNF rescues BAF53b-dependent synaptic plasticity and cocaine-associated memory in the nucleus accumbens

scientific article

CD11a expression distinguishes infiltrating myeloid cells from plaque-associated microglia in Alzheimer's disease

scientific article published on 26 December 2018

Caspase-cleavage of tau is an early event in Alzheimer disease tangle pathology

article

Caspase-mediated degeneration in Alzheimer's disease

scientific article published in August 2004

Concise review: Can stem cells be used to treat or model Alzheimer's disease?

scientific article published on December 2012

Deletion of a Csf1r enhancer selectively impacts CSF1R expression and development of tissue macrophage populations

scientific article published on 19 July 2019

Development and validation of a simplified method to generate human microglia from pluripotent stem cells

article

Efficacy and immunogenicity of MultiTEP-based DNA vaccines targeting human α-synuclein: prelude for IND enabling studies

scientific article published on 10 January 2022

Eliminating microglia in Alzheimer's mice prevents neuronal loss without modulating amyloid-β pathology.

scientific article

Estradiol-induced modulation of estrogen receptor-beta and GABA within the adult neocortex: a potential transsynaptic mechanism for estrogen modulation of BDNF.

scientific article published in December 2006

Estrogen receptor-beta colocalizes extensively with parvalbumin-labeled inhibitory neurons in the cortex, amygdala, basal forebrain, and hippocampal formation of intact and ovariectomized adult rats.

scientific article

Gamma oscillations in the entorhinal-hippocampal circuit underlying memory and dementia.

scientific article published on 10 February 2018

Gene expression and functional deficits underlie TREM2-knockout microglia responses in human models of Alzheimer's disease

scientific article published on 23 October 2020

HuCNS-SC Human NSCs Fail to Differentiate, Form Ectopic Clusters, and Provide No Cognitive Benefits in a Transgenic Model of Alzheimer's Disease.

scientific article published on February 2017

Human Neural Progenitor Transplantation Rescues Behavior and Reduces α-Synuclein in a Transgenic Model of Dementia with Lewy Bodies.

scientific article

Human neural stem cells improve cognition and promote synaptic growth in two complementary transgenic models of Alzheimer's disease and neuronal loss

scientific article

Humanized monoclonal antibody armanezumab specific to N-terminus of pathological tau: characterization and therapeutic potency

scientific article

Increased tauopathy drives microglia-mediated clearance of beta-amyloid.

scientific article published on 23 June 2016

Induction of Mesoderm and Neural Crest-Derived Pericytes from Human Pluripotent Stem Cells to Study Blood-Brain Barrier Interactions

scientific article published on 07 February 2019

Inhibition of soluble TNF signaling in a mouse model of Alzheimer's disease prevents pre-plaque amyloid-associated neuropathology

scientific article

Integrated analysis of genetic, behavioral, and biochemical data implicates neural stem cell-induced changes in immunity, neurotransmission and mitochondrial function in Dementia with Lewy Body mice.

scientific article

Longitudinal behavioral and 6-[18F]fluoro-L-DOPA-PET assessment in MPTP-hemiparkinsonian monkeys

scientific article

Microglia in Alzheimer's Disease: Exploring How Genetics and Phenotype Influence Risk

scientific article published on 07 February 2019

MultiTEP platform-based DNA epitope vaccine targeting N-terminus of tau induces strong immune responses and reduces tau pathology in THY-Tau22 mice.

scientific article

Neural Stem Cells Rescue Cognitive and Motor Dysfunction in a Transgenic Model of Dementia with Lewy Bodies through a BDNF-Dependent Mechanism

scientific article

Neural stem cell therapy for neurodegenerative disorders: The role of neurotrophic support.

scientific article published on 17 February 2017

Neural stem cells genetically-modified to express neprilysin reduce pathology in Alzheimer transgenic models

scientific article

Neural stem cells improve cognition via BDNF in a transgenic model of Alzheimer disease.

scholarly article

Neural stem cells improve memory in an inducible mouse model of neuronal loss.

scientific article

Neuronal-specific overexpression of a mutant valosin-containing protein associated with IBMPFD promotes aberrant ubiquitin and TDP-43 accumulation and cognitive dysfunction in transgenic mice.

scientific article published on 05 June 2013

Response to StemCells Inc.

scientific article published on February 2017

Soluble amyloid precursor protein induces rapid neural differentiation of human embryonic stem cells.

scientific article published on 23 May 2011

Swedish Alzheimer mutation induces mitochondrial dysfunction mediated by HSP60 mislocalization of amyloid precursor protein (APP) and beta-amyloid

scientific article

The CD22-IGF2R interaction is a therapeutic target for microglial lysosome dysfunction in Niemann-Pick type C

scientific article published on 01 December 2021

The adaptive immune system restrains Alzheimer's disease pathogenesis by modulating microglial function

scientific article published on 16 February 2016

iPSC-Derived Human Microglia-like Cells to Study Neurological Diseases.

scientific article

β-Amyloid impairs axonal BDNF retrograde trafficking

scientific article

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