Search filters

List of works by Ulrich Kintscher

2018 ESC Guidelines for the management of cardiovascular diseases during pregnancy

A non-thiazolidinedione partial peroxisome proliferator-activated receptor gamma ligand inhibits vascular smooth muscle cell growth

scientific article published in April 2003

ANP system activity predicts variability of fat mass reduction and insulin sensitivity during weight loss

scientific article

AT1-receptor blockade attenuates outward aortic remodeling associated with diet-induced obesity in mice

scientific article published on 23 June 2017

ATR (Angiotensin AT2 Receptor) Agonist, Compound 21, Prevents Abdominal Aortic Aneurysm Progression in the Rat

scientific article published on 01 September 2018

Accurate assessment of LV function using the first automated 2D-border detection algorithm for small animals - evaluation and application to models of LV dysfunction

scientific article published on 22 April 2019

Adipose Tissue Lipolysis Promotes Exercise-induced Cardiac Hypertrophy Involving the Lipokine C16:1n7-Palmitoleate

scientific article

Adipose tissue ATGL modifies the cardiac lipidome in pressure-overload-induced left ventricular failure.

scientific article published on 10 January 2018

And in the end—Telmisartan directly binds to PPARγ ⬇️

scientific article published on March 22, 2012

Angiotensin II induces peroxisome proliferator-activated receptor gamma in PC12W cells via angiotensin type 2 receptor activation

scientific article published on 30 June 2005

Angiotensin II receptor expression: from maturation to pathogenesis

scientific article published in July 2003

Angiotensin II type 1-receptor activating antibodies in renal-allograft rejection

scientific article published in February 2005

Angiotensin II type 2 receptor stimulation: a novel option of therapeutic interference with the renin-angiotensin system in myocardial infarction?

scientific article

Angiotensin II, PPAR-gamma and atherosclerosis

scientific article published on January 2004

Angiotensin II-accelerated atherosclerosis and aneurysm formation is attenuated in osteopontin-deficient mice

scientific article published on November 2003

Angiotensin II-augmented migration of VSMCs towards PDGF-BB involves Pyk2 and ERK 1/2 activation.

scientific article published in July 2002

Angiotensin type 1 receptor blockers induce peroxisome proliferator-activated receptor-gamma activity

scientific article published on 26 April 2004

Angiotensin type 2 receptor stimulation ameliorates left ventricular fibrosis and dysfunction via regulation of tissue inhibitor of matrix metalloproteinase 1/matrix metalloproteinase 9 axis and transforming growth factor β1 in the rat heart

scientific article published on 30 December 2013

Application of Speckle-Tracking Echocardiography in an Experimental Model of Isolated Subendocardial Damage

scientific article published on 21 October 2017

Benefit of Blood Pressure Control in Diabetic Patients

scientific article published on July 2015

Bezafibrate maintenance therapy in patients with advanced chronic hepatitis C.

scientific article published on May 2013

Cannabinoid receptor 1 inhibition improves cardiac function and remodelling after myocardial infarction and in experimental metabolic syndrome

scientific article published in May 2013

Cardiac PPARalpha expression in patients with dilated cardiomyopathy

scientific article published on 22 November 2005

Cardiovascular magnetic resonance feature tracking in small animals - a preliminary study on reproducibility and sample size calculation

scientific article

Characterization of new PPARgamma agonists: analysis of telmisartan's structural components

scientific article published on March 2009

Characterization of new PPARgamma agonists: benzimidazole derivatives - the importance of position 2.

scientific article

Characterization of new PPARgamma agonists: benzimidazole derivatives-importance of positions 5 and 6, and computational studies on the binding mode

scientific article published on 3 July 2010

Characterization of telmisartan-derived PPARγ agonists: importance of moiety shift from position 6 to 5 on potency, efficacy and cofactor recruitment

scientific article

Chronic treatment with losartan results in sufficient serum levels of the metabolite EXP3179 for PPARgamma activation

scientific article published on 17 August 2009

Comparison between single and combined treatment with candesartan and pioglitazone following transient focal ischemia in rat brain

scientific article published on 4 March 2008

Deoxycorticosterone acetate-salt mice exhibit blood pressure-independent sexual dimorphism

scientific article published on 7 February 2008

Does the AT2-receptor mediate anti-atherosclerotic actions?

scientific article published in August 2005

Effect of high-dose valsartan on inflammatory and lipid parameters in patients with Type 2 diabetes and hypertension

scientific article published in September 2010

Effects of empagliflozin and target-organ damage in a novel rodent model of heart failure induced by combined hypertension and diabetes

scientific article published on 20 August 2020

Endothelial dysfunction and its role in diabetic vascular disease

scientific article published on September 2006

Enhanced insulin signaling in density-enhanced phosphatase-1 (DEP-1) knockout mice

scientific article published on 12 February 2015

Estrogen receptor alpha supports cardiomyocytes indirectly through post-infarct cardiac c-kit+ cells

scientific article published on 31 March 2009

Estrogen receptor-beta signals left ventricular hypertrophy sex differences in normotensive deoxycorticosterone acetate-salt mice

scientific article published on 7 February 2011

Evaluation of a commercial multi-dimensional echocardiography technique for ventricular volumetry in small animals.

scientific article

Expression of matrix metalloproteinase-11 is increased under conditions of insulin resistance

scientific article published on September 2017

Female sex and estrogen receptor-beta attenuate cardiac remodeling and apoptosis in pressure overload

scientific article

Free fatty acids link metabolism and regulation of the insulin-sensitizing fibroblast growth factor-21.

scientific article published on 28 April 2009

Gender in cardiovascular diseases: impact on clinical manifestations, management, and outcomes

scientific article published on 3 November 2015

Glucose-dependent insulinotropic polypeptide reduces fat-specific expression and activity of 11β-hydroxysteroid dehydrogenase type 1 and inhibits release of free fatty acids

scientific article published on 16 December 2011

High-Dose Treatment With Telmisartan Induces Monocytic Peroxisome Proliferator-Activated Receptor-γ Target Genes in Patients With the Metabolic Syndrome ⬇️

scientific article published on August 29, 2011

High-Fat Diet Induces Unexpected Fatal Uterine Infections in Mice with aP2-Cre-mediated Deletion of Estrogen Receptor Alpha

scientific article published on 24 February 2017

Histone deacetylase 6 (HDAC6) is an essential modifier of glucocorticoid-induced hepatic gluconeogenesis

scientific article published on 30 December 2011

Hypertension 2012--still a challenge ⬇️

scientific article published on November 20, 2012

Hypertension and diabetes: target blood pressure and blood pressure lowering by new antidiabetic drugs

scientific article published on 19 November 2014

Hypoxia activates beta(1)-integrin via ERK 1/2 and p38 MAP kinase in human vascular smooth muscle cells

scientific article

INT-131, a PPARgamma agonist for the treatment of type 2 diabetes.

scientific article published on April 2009

Impact of HDL on adipose tissue metabolism and adiponectin expression

scientific article

Importance of 5/6-aryl substitution on the pharmacological profile of 4'-((2-propyl-1H-benzo[d]imidazol-1-yl)methyl)-[1,1'-biphenyl]-2-carboxylic acid derived PPARγ agonists

scientific article published on 25 November 2016

Inflammatory Pathways Regulated By Tumor-Necrosis Receptor Associated Factor 1 Protect From Metabolic Consequences In Diet-Induced Obesity

scientific article published on 22 January 2018

Inhibition of Src homology 2 domain-containing phosphatase 1 increases insulin sensitivity in high-fat diet-induced insulin-resistant mice

scientific article published on 4 January 2016

Insulin facilitates monocyte migration: a possible link to tissue inflammation in insulin-resistance

scientific article published on 20 November 2007

Irbesartan for the treatment of hypertension in patients with the metabolic syndrome: a sub analysis of the Treat to Target post authorization survey. Prospective observational, two armed study in 14,200 patients

scientific article published on 3 April 2007

Leptin induces endothelial cell migration through Akt, which is inhibited by PPARgamma-ligands

scientific article published on November 2002

Liver-specific peroxisome proliferator-activated receptor alpha target gene regulation by the angiotensin type 1 receptor blocker telmisartan

scientific article published on 9 January 2008

Metabolic actions of estrogen receptor beta (ERbeta) are mediated by a negative cross-talk with PPARgamma

scientific article

Metabolic impact of estrogen signalling through ERalpha and ERbeta

scientific article published on 03 July 2010

Molecular characterization of new selective peroxisome proliferator-activated receptor gamma modulators with angiotensin receptor blocking activity

scientific article published on December 2005

Mortality and morbidity in different immunization protocols for experimental autoimmune myocarditis in rats

scientific article published on 24 February 2014

New telmisartan-derived PPARγ agonists: Impact of the 3D-binding mode on the pharmacological profile

scientific article published on 15 August 2016

ONTARGET, TRANSCEND, and PRoFESS: new-onset diabetes, atrial fibrillation, and left ventricular hypertrophy.

scientific article published in June 2009

Olmesartan after experimental myocardial infarct compared with ramipril: organ protective effect

scientific article published in January 2005

Optimal treatment of obesity-related hypertension: the Hypertension-Obesity-Sibutramine (HOS) study

scientific article published on 2 April 2007

PCSK9 regulates the chemokine receptor CCR2 on monocytes

scientific article published on 20 February 2017

PPAR activators inhibit endothelial cell migration by targeting Akt.

scientific article

PPARalpha inhibits TGF-beta-induced beta5 integrin transcription in vascular smooth muscle cells by interacting with Smad4.

scientific article published in November 2002

PPARgamma activation attenuates T-lymphocyte-dependent inflammation of adipose tissue and development of insulin resistance in obese mice

scientific article published on 18 October 2010

PPARgamma-activating angiotensin type-1 receptor blockers induce adiponectin

scientific article published on 6 June 2005

PPARgamma-mediated insulin sensitization: the importance of fat versus muscle

scientific article

Pharmacological differences of glitazones: does peroxisome proliferator-activated receptor-alpha activation make the difference?

scientific article published on 9 July 2008

Proprotein convertase furin enhances survival and migration of vascular smooth muscle cells via processing of pro-nerve growth factor

scientific article

Proprotein convertase subtilisin/kexin type 3 promotes adipose tissue-driven macrophage chemotaxis and is increased in obesity

scientific article published on 06 August 2013

Prorenin engages the (pro)renin receptor like renin and both ligand activities are unopposed by aliskiren

scientific article published in September 2008

Rationale and design of a large registry on renal denervation: the Global SYMPLICITY registry

scientific article

Regulation of peroxisome proliferator-activated receptor gamma activity by losartan metabolites

scientific article published on 19 December 2005

Response to Comment on: Winkler et al. Histone Deacetylase 6 (HDAC6) Is an Essential Modifier of Glucocorticoid-Induced Hepatic Gluconeogenesis. Diabetes 2012;61:513–523.

scientific article published on 15 June 2012

Reuptake Inhibitors of Dopamine, Noradrenaline, and Serotonin ⬇️

scientific article published on January 1, 2012

Role of the adipocyte-specific NF-κB activity in the regulation of IP-10 and T cell migration

scientific article published on 9 November 2010

Selective Mineralocorticoid Receptor Cofactor Modulation as Molecular Basis for Finerenone's Antifibrotic Activity

scientific article published on 5 February 2018

Sex Differences in Cardiac Mitochondria in the New Zealand Obese Mouse

article

Sex and sex hormone-dependent cardiovascular stress responses

scientific article

Sex differences in exercise-induced cardiac hypertrophy

scientific article published on 17 February 2013

Sex differences in physiological cardiac hypertrophy are associated with exercise-mediated changes in energy substrate availability.

scientific article

Sex- and age-dependent effects of Gpr30 genetic deletion on the metabolic and cardiovascular profiles of diet-induced obese mice

scientific article published on 26 February 2014

Sex-specific differences in Type 2 Diabetes Mellitus and dyslipidemia therapy: PPAR agonists

scientific article published on January 2012

Sex-specific mTOR signaling determines sexual dimorphism in myocardial adaptation in normotensive DOCA-salt model

scientific article published on 21 January 2013

Sexual dimorphic regulation of body weight dynamics and adipose tissue lipolysis

scientific article

Sexual dimorphism in obesity-mediated left ventricular hypertrophy

scientific article

Statins regulate alpha2beta1-integrin expression and collagen I-dependent functions in human vascular smooth muscle cells

scientific article

Steroidal and Nonsteroidal Mineralocorticoid Receptor Antagonists Cause Differential Cardiac Gene Expression in Pressure Overload-induced Cardiac Hypertrophy

scientific article published on 5 February 2016

TGF-beta(1) induces peroxisome proliferator-activated receptor gamma1 and gamma2 expression in human THP-1 monocytes

scientific article published on October 2002

Targeting density-enhanced phosphatase-1 (DEP-1) with antisense oligonucleotides improves the metabolic phenotype in high-fat diet-fed mice

scientific article published on 26 July 2013

Telmisartan inhibits CD4-positive lymphocyte migration independent of the angiotensin type 1 receptor via peroxisome proliferator-activated receptor-gamma

scientific article published on 24 December 2007

The cardiometabolic drug rimonabant: after 2 years of RIO-Europe and STRADIVARIUS.

scientific article published on 13 June 2008

The cytoskeleton in 'couch potato-ism': Insights from a murine model of impaired actin dynamics

scientific article published on 20 April 2018

The endothelium and vascular inflammation in diabetes

scientific article published on June 2007

The individualized obesity paradox

scientific article published on 4 December 2013

The metabolic syndrome: cluster with a self-fulfilling loop?

scientific article published in February 2006

Therapy of hypertension--2015

scientific article published on 28 May 2015

p38 MAP kinase negatively regulates angiotensin II-mediated effects on cell cycle molecules in human coronary smooth muscle cells

scientific article published in June 2003

Paulina is supported by:

About Paulina

Help