List of works by Klaus Jung

20-25% lower concentrations of total and free prostate-specific antigen (PSA) after calibration of PSA assays to the WHO reference materials--analysis of 1098 patients in four centers

scientific article published in April 2009

31P-NMR spectroscopy and ultrastructural studies on nephrotoxicity of cyclosporine A.

scientific article

A (-5, -7) proPSA based artificial neural network to detect prostate cancer.

scientific article

A Bibliometric Evaluation of Publications in Urological Journals among European Union Countries between 2000–2005

scientific article published on 18 July 2007

A Gap Between Total Prostate-specific Antigen and the Sum of Free Prostate-specific Antigen Plus α1-Antichymotrypsin-Prostate-specific Antigen in Patients with Prostate Carcinoma but not in Those with Benign Prostate Hyperplasia ⬇️

scholarly article

A Novel Predictor Tool of Biochemical Recurrence after Radical Prostatectomy Based on a Five-MicroRNA Tissue Signature

scientific article published on 21 October 2019

A [-2]proPSA-based artificial neural network significantly improves differentiation between prostate cancer and benign prostatic diseases.

scientific article published in February 2009

A microalbuminuria assay using bromphenol blue

scientific article published in February 1990

A multicenter clinical trial on the use of (-5, -7) pro prostate specific antigen.

scientific article published in December 2005

A multicenter clinical trial on the use of alpha1-antichymotrypsin-prostate-specific antigen in prostate cancer diagnosis.

scientific article published in May 2001

A multicenter clinical trial on the use of complexed prostate specific antigen in low prostate specific antigen concentrations.

scientific article published in October 2003

A new algorithm for integrated analysis of miRNA-mRNA interactions based on individual classification reveals insights into bladder cancer.

scientific article

A new sensitivity-preferred strategy to build prediction rules for therapy response of cancer patients using gene expression data.

scientific article

A practical new assay for determining N-acetyl-β-D-glucosaminidase activity in urine

scientific article published on 01 December 1991

A review of expression profiling of circulating microRNAs in men with prostate cancer.

scientific article

A strong note of caution in using matrix metalloproteinase-1 and its inhibitor, TIMP-1 in serum as biomarkers in systolic heart failure

scientific article published on 13 March 2008

ACT-PSA and complexed PSA elimination kinetics in serum after radical retropubic prostatectomy: proof of new complex forming of PSA after release into circulation.

scientific article published in April 2000

ADAM8 expression in prostate cancer is associated with parameters of unfavorable prognosis.

scientific article published on 8 November 2006

ADAM9 expression is a significant and independent prognostic marker of PSA relapse in prostate cancer.

scientific article published on 26 November 2007

ADAM9 is highly expressed in renal cell cancer and is associated with tumour progression

scientific article

Adenosine formation by isolated rat kidney mitochondria

scientific article published on 01 August 1989

Adipophilin as prognostic biomarker in clear cell renal cell carcinoma

scientific article

Advances in Biomarkers for PCa Diagnostics and Prognostics-A Way towards Personalized Medicine.

scientific article published on 20 October 2017

An Optimized Micromethod for Determining the Catalytic Activity of Serum Ribonuclease

scientific article published on 01 April 1986

An artificial neural network considerably improves the diagnostic power of percent free prostate-specific antigen in prostate cancer diagnosis: results of a 5-year investigation.

scientific article published in May 2002

An artificial neural network for five different assay systems of prostate-specific antigen in prostate cancer diagnostics

scientific article

An optimized assay of alanine aminopeptidase activity in urine ⬇️

scientific article published on 01 August 1980

Analysis of subforms of free prostate-specific antigen in serum by two-dimensional gel electrophoresis: potential to improve diagnosis of prostate cancer.

scientific article published on 7 October 2004

Analytical Aspects regarding the Measurement of Metalloproteinases

scientific article published on 01 June 1999

Analytical aspects regarding the measurement of metalloproteinases and their inhibitors in blood.

scientific article

Antioxidant and antiproliferative potentials of methanol extract of Xylopia aethiopica (Dunal) A. Rich in PC-3 and LNCaP cells

scientific article published on 01 July 2017

Antioxidant enzymes in malignant prostate cell lines and in primary cultured prostatic cells.

scientific article

Antioxidant, antiangiogenic and antiproliferative activities of root methanol extract of Calliandra portoricensis in human prostate cancer cells

scientific article

Apelin and apelin receptor expression in renal cell carcinoma

scientific article published on 20 February 2019

Artificial neural network (ANN) velocity better identifies benign prostatic hyperplasia but not prostate cancer compared with PSA velocity

scientific article

Artificial neural networks and prostate cancer--tools for diagnosis and management.

scientific article published on 12 February 2013

Artificial neural networks: has the time come for their use in prostate cancer patients?

scientific article published in June 2005

Assay-dependent abnormalities in measurements of prostate-specific antigen in serum: an occasional occurrence, but of clinical significance

scientific article published on 20 December 2011

Assay-specific artificial neural networks for five different PSA assays and populations with PSA 2-10 ng/ml in 4,480 men.

scientific article

Avoiding pitfalls in applying prediction models, as illustrated by the example of prostate cancer diagnosis.

scientific article published on 15 September 2011

BAY 1024767 blocks androgen receptor mutants found in castration-resistant prostate cancer patients

scientific article published on 9 January 2016

Benign prostatic hyperplasia-associated free prostate-specific antigen improves detection of prostate cancer in an artificial neural network.

scientific article published on 24 May 2009

Betaine improves the PCR amplification of GC-rich DNA sequences

scientific article

Between-method differences in prostate-specific antigen assays affect prostate cancer risk prediction by nomograms.

scientific article

Blood sampling affects circulating TIMP-1 concentration, a useful biomarker in estimating liver fibrosis stages

article

Blood sampling and the measurement of circulating matrix metalloproteinase-8

scientific article published on 22 November 2007

Blood sampling as critical preanalytical determinant to use circulating MMP and TIMP as surrogate markers for pathological processes

scientific article published on 01 October 2005

Blood specimen collection methods influence the concentration and the diagnostic validity of matrix metalloproteinase 9 in blood

scientific article published on 01 December 2001

Bone turnover markers as predictive tools for skeletal complications in men with metastatic prostate cancer treated with zoledronic acid.

scientific article published in May 2009

Bone turnover markers as predictors of mortality risk in prostate cancer patients with bone metastases following treatment with zoledronic acid.

scientific article published on 22 December 2010

Bone turnover markers in serum and urine as diagnostic, prognostic and monitoring biomarkers of bone metastasis.

scientific article published on 08 September 2014

Brain-type and liver-type fatty acid-binding proteins: new tumor markers for renal cancer?

scientific article published on 21 July 2009

By mistakes we learn: determination of matrix metalloproteinase-8 and tissue inhibitor of matrix metalloproteinase-1 in serum yields doubtful results

scientific article published on 01 January 2009

CD146 protein in prostate cancer: revisited with two different antibodies

scientific article

CD24 expression is a significant predictor of PSA relapse and poor prognosis in low grade or organ confined prostate cancer.

scientific article published in February 2004

Calibration of the oxygen content in fluids for polarographic respiration studies

scientific article published on 01 January 1972

Careful attention to blood sampling as a preanalytical determinant of circulating matrix metalloproteinase 9 to avoid misinterpretations: comment on the article by Ainiala et al.

scientific article

Cathepsins B, H, L and cysteine protease inhibitors in malignant prostate cell lines, primary cultured prostatic cells and prostatic tissue.

scientific article published in January 1999

Cathepsins B, H, L and cysteine proteinase inhibitors in renal cell carcinoma: no evidence for dysregulated proteolytic balance

scientific article published on 01 January 1998

Cathepsins B, H, and L activities in urine of patients with transitional cell carcinoma of the bladder

scientific article published in February 2002

Cell-free DNA in the blood as a solid tumor biomarker--a critical appraisal of the literature.

scientific article published on 02 August 2010

Changed enzyme activities in rat kidney during ischemia

scientific article published on 01 November 1985

Changed excretion of urinary proteins and enzymes by chronic exposure to lead.

scientific article published in January 1994

Changes in Concentration of DNA in Serum and Plasma during Storage of Blood Samples

scientific article published on 01 June 2003

Circular RNAs and Their Linear Transcripts as Diagnostic and Prognostic Tissue Biomarkers in Prostate Cancer after Prostatectomy in Combination with Clinicopathological Factors

scientific article published on 22 October 2020

Circular RNAs in Clear Cell Renal Cell Carcinoma: Their Microarray-Based Identification, Analytical Validation, and Potential Use in a Clinico-Genomic Model to Improve Prognostic Accuracy

scientific article published on 30 September 2019

Circular RNAs: a new class of biomarkers as a rising interest in laboratory medicine

Circulating Matrix Metalloproteinase-7: An Early or Metastatic Marker for Renal Cell Carcinoma?

scientific article published on 01 November 2008

Circulating gelatinase B (MMP-9)—the impact of the preanalytical step of blood collectionRE: Zymographic analysis of circulating and tissue forms of colon carcinoma gelatinase A (MMP-2) and B (MMP-9) separated by mono- and two-dimensional electroph

scientific article published on 01 August 2002

Circulating miRNAs in blood and urine as diagnostic and prognostic biomarkers for bladder cancer: an update in 2017

scientific article published in 2018

Class I histone deacetylases 1, 2 and 3 are highly expressed in renal cell cancer.

scientific article published on 19 December 2008

Class II antigen expression by keratinocytes and enterocytes--an early feature of graft-versus-host-disease

scientific article published on 01 September 1988

Claudin-1 Protein Expression is a Prognostic Marker of Patient Survival in Renal Cell Carcinomas

scientific article published on 01 November 2008

Clinical implications of AGR2 in primary prostate cancer: Results from a large‐scale study

scholarly article

Clinical utility of human glandular kallikrein 2 within a neural network for prostate cancer detection.

scientific article published in September 2005

Combined determination of plasma MMP2, MMP9, and TIMP1 improves the non-invasive detection of transitional cell carcinoma of the bladder

scientific article

Comparative assessment of urinary prostate cancer antigen 3 and TMPRSS2:ERG gene fusion with the serum [-2]proprostate-specific antigen-based prostate health index for detection of prostate cancer.

scientific article

Comparative determinations of aminotransferase activities in serum with so-called “optimised” methods

scientific article published on 01 December 1977

Comparison between Equimolar- and Skewed-Response Assays of Prostate Specific Antigen: Is There an Influence on the Clinical Significance When Measuring Total Serum Prostate Specific Antigen?

scientific article published on 01 May 1996

Comparison of 10 serum bone turnover markers in prostate carcinoma patients with bone metastatic spread: diagnostic and prognostic implications.

scientific article

Comparison of Eight Computer Programs for Receiver-Operating Characteristic Analysis

scientific article (publication date: March 2003)

Comparison of global tests for functional gene sets in two-group designs and selection of potentially effect-causing genes

scientific article

Comparison of p40 (ΔNp63) and p63 expression in prostate tissues--which one is the superior diagnostic marker for basal cells?

scientific article published on 13 May 2013

Comparison of the Clinical Validity of Free Prostate–Specific Antigen, Alpha–1 Antichymotrypsin–Bound Prostate–Specific Antigen and Complexed Prostate–Specific Antigen in Prostate Cancer Diagnosis

scientific article published on 01 January 2001

Comparison of the diagnostic value of fatty acid synthase (FASN) with alpha-methylacyl-CoA racemase (AMACR) as prostatic cancer tissue marker

scientific article published on 01 May 2010

Comparison of the effects of the immunosuppressive agents FK 506 and cyclosporin A on rat kidney mitochondria.

scientific article published in September 1993

Comparison of the micronucleus and chromosome aberration techniques for the documentation of cytogenetic damage in radiochemotherapy-treated patients with rectal cancer

scientific article published on 23 December 2010

Comparison of two different artificial neural networks for prostate biopsy indication in two different patient populations.

scientific article

Complications, urinary continence, and oncologic outcome of 1000 laparoscopic transperitoneal radical prostatectomies-experience at the Charité Hospital Berlin, Campus Mitte.

scientific article published on 5 July 2006

Comprehensive Evaluation of Prostate-Specific Membrane Antigen Expression in the Vasculature of Renal Tumors: Implications for Imaging Studies and Prognostic Role.

scientific article

Consideration of Preanalytical Conditions to Use Circulating Matrix Metalloproteinases as Diagnostic Markers

scientific article published on 01 March 2005

Consideration of important preanalytical conditions for the assessment of circulating matrix metalloproteinase-9.

scientific article

Consideration of preanalytical impact of blood sampling on measurement of matrix metalloproteinases and their inhibitors as precondition to evaluate their relationship to clinical data

scientific article published on 01 November 2009

Cooperative Effect of miR-141-3p and miR-145-5p in the Regulation of Targets in Clear Cell Renal Cell Carcinoma.

scientific article

CpG island methylator phenotype infers a poor disease-free survival in locally advanced rectal cancer

scientific article published on 14 October 2011

Creatine kinase isoenzyme BB in serum of healthy adults and children

scientific article published on 01 January 1979

Creatine kinase isoenzyme BB in serum of patients undergoing chronic hemodialysis and with kidney transplant

scientific article published on January 1979

Culture of Human Kidney Proximal Tubular Cells – The Effect of Various Detachment Procedures on Viability and Degree of Cell Detachment

article

Current biomarkers for diagnosing of prostate cancer

scientific article published on 11 September 2015

Cyclosporine a inhibits ATP net uptake of rat kidney mitochondria

scientific article published on 01 March 1992

Cystatin C: a promising marker of glomerular filtration rate to replace creatinine

scientific article published on 01 January 1995

Decreased RECK and Increased EMMPRIN expression in urothelial carcinoma of the bladder are associated with tumor aggressiveness

scientific article published on 26 May 2011

Decreased RECK expression indicating proteolytic imbalance in prostate cancer is associated with higher tumor aggressiveness and risk of prostate-specific antigen relapse after radical prostatectomy.

scientific article

Decreased concentrations of prostate-specific antigen and human glandular kallikrein 2 in malignant versus nonmalignant prostatic tissue

scientific article published on 01 September 2000

Decreased mitochondrial DNA content drives OXPHOS dysregulation in chromophobe renal cell carcinoma

scientific article published on 21 July 2020

Defined morphological criteria allow reliable diagnosis of colorectal serrated polyps and predict polyp genetics.

scientific article published on 12 April 2014

Deregulation of the COP9 signalosome-cullin-RING ubiquitin-ligase pathway: mechanisms and roles in urological cancers.

scientific article published on 10 April 2013

Detection of human kallikrein 4 in healthy and cancerous prostatic tissues by immunofluorometry and immunohistochemistry

scientific article published on 01 August 2002

Determination of Non- 1-Antichymotrypsin-complexed Prostate-specific Antigen as an Indirect Measurement of Free Prostate-specific Antigen: Analytical Performance and Diagnostic Accuracy

scientific article published on 01 June 2003

Determination of alpha1-antichymotrypsin-PSA complex in serum does not improve the differentiation between benign prostatic hyperplasia and prostate cancer compared with total PSA and percent free PSA.

scientific article published on June 1999

Determination of purine compounds by ion-pair microbore high-performance liquid chromatography: application to ischemic rat kidney mitochondria

scientific article published on 01 May 1990

Development of an immunoenzymometric assay for alpha 1-microglobulin and measurement of its serum concentration in normal and HIV-infected persons

scientific article published on October 1, 1990

Developmental changes of antioxidant enzymes in kidney and liver from rats.

scientific article published in January 1996

Diagnostic and Prognostic Potential of MicroRNA Maturation Regulators Drosha, AGO1 and AGO2 in Urothelial Carcinomas of the Bladder

scientific article published on 31 May 2018

Diagnostic and prognostic implications of microRNA profiling in prostate carcinoma

scientific article

Diagnostic and prognostic potential of circulating cell-free genomic and mitochondrial DNA fragments in clear cell renal cell carcinoma patients

scientific article

Diagnostic and prognostic potential of differentially expressed miRNAs between metastatic and non-metastatic renal cell carcinoma at the time of nephrectomy.

scientific article published on 21 November 2012

Diagnostic and prognostic validity of serum bone turnover markers in metastatic renal cell carcinoma.

scientific article published in October 2006

Diagnostic and prognostic value of T-cell receptor gamma alternative reading frame protein (TARP) expression in prostate cancer

scientific article published on 01 June 2010

Diagnostic sensitivity of serum cystatin for impaired glomerular filtration rate.

scientific article published in August 1999

Diagnostic significance of different urinary enzymes in patients suffering from chronic renal diseases

scientific article published on 01 October 1987

Diagnostic significance of urinary enzymes in detecting acute rejection crises in renal transplant recipients depending on expression of results illustrated through the example of alanine aminopeptidase

scientific article published on August 1985

Diagnostic validity of macrophage migration inhibitory factor in serum of patients with prostate cancer: a re-evaluation.

scientific article published in January 2005

Diagnostic, prognostic and therapeutic implications of microRNAs in urologic tumors

scientific article published on 06 April 2010

Different effects of cyclosporine and tacrolimus on the activation of mesangial metalloproteinases and their inhibitors

scientific article published on 01 November 1999

Different mRNA and Protein Expression of Matrix Metalloproteinases 2 and 9 and Tissue Inhibitor of Metalloproteinases 1 in Benign and Malignant Prostate Tissue

scientific article published on 01 October 2002

Different prostate-specific antigen assays give different results on the same blood sample: an obstacle to recommending uniform limits for prostate biopsies.

scientific article published on 12 March 2007

Differential expression of Kallikrein gene 5 in cancerous and normal testicular tissues

scientific article (publication date: October 2002)

Differential expression of a human kallikrein 5 (KLK5) splice variant in ovarian and prostate cancer

scientific article published on May 2004

Differential expression of matrix metalloproteinases and their tissue inhibitors in human primary cultured prostatic cells and malignant prostate cell lines.

scientific article

Differential expression of the human kallikrein gene 14 (KLK14) in normal and cancerous prostatic tissues

scientific article

Differential gene expression of urokinase-type plasminogen activator and its receptor in human renal cell carcinoma.

scientific article published in September 2005

Differential response of oxygen radical metabolism in rat heart, liver and kidney to cyclosporine A treatment

scientific article published on 01 November 1997

Dimethyl sulfoxide as additive in ready-to-use reaction mixtures for real-time polymerase chain reaction analysis with SYBR Green I dye.

scientific article

Discordance analysis characteristics as a new method to compare the diagnostic accuracy of tests: example of complexed versus total prostate-specific antigen.

scientific article published in March 2005

Discordant total and free prostate-specific antigen (PSA) assays: does calibration with WHO reference materials diminish the problem?

scientific article published on January 2009

Discovery and validation of 3 novel DNA methylation markers of prostate cancer prognosis

scientific article

Diuresis-dependent excretion of multiple forms of renal brush-border enzymes in urine

scientific article published on 01 April 1986

Diuresis-dependent excretions of low-molecular mass proteins in urine: β2-microglobulin, lysozyme, and ribonuclease

scientific article published on 01 February 1988

Divergent effects of taurolidine as potential anti-neoplastic agent: Inhibition of bladder carcinoma cells in vitro and promotion of bladder tumor in vivo

Divergent effects of taurolidine as potential anti-neoplastic agent: inhibition of bladder carcinoma cells in vitro and promotion of bladder tumor in vivo.

scientific article

Does the Prostate Health Index Depend on Tumor Volume?-A Study on 196 Patients after Radical Prostatectomy.

scientific article published on 24 February 2017

Down-regulation of the human kallikrein gene 5 (KLK5) in prostate cancer tissues

scientific article (publication date: May 2002)

Down-regulation of the pro-apoptotic XIAP associated factor-1 (XAF1) during progression of clear-cell renal cancer

scientific article published on 8 August 2009

Editorial Comment

Editorial Comment

Editorial Comment on: Diagnostic Value of Free Prostate-Specific Antigen among Men with a Prostate-Specific Antigen Level of <3.0μg per Liter

scientific article published on 05 November 2007

Effect of Storage Temperature on the Activity of Superoxide Dismutase, Catalase, Glutathione Peroxidase, Glutathione Reductase and Glutathione S-Transferase in Rat Liver and Kidney Homogenates

scientific article published on 01 January 1993

Effect of pyridoxal 5'-phosphate on the temperature relationships of alanine aminotransferase

scientific article published in November 1975

Effect of quinolinyl acrylate derivatives on prostate cancer in vitro and in vivo.

scientific article published on 12 July 2011

Ein farbtest zur bestimmung der glutamatdehydrogenase-aktivität im serum

scientific article published on 01 January 1972

Electrophoretic Subforms of Free Prostate-Specific Antigen in Serum as Promising Diagnostic Tool in Prostate Cancer Diagnostics

scientific article published on 01 February 2007

Elevated plasma osteopontin as marker for distant metastases and poor survival in patients with renal cell carcinoma

scientific article published on 04 May 2007

Elimination of Serum Complexed Prostate-Specific Antigen after Radical Retropubic Prostatectomy

scientific article published on 01 April 2000

Elimination of Serum Free and Total Prostate-Specific Antigen after Radical Retropubic Prostatectomy

scientific article published on 01 August 1997

Endocytosis-mediated replenishment of amino acids favors cancer cell proliferation and survival in chromophobe renal cell carcinoma

scientific article published on 28 October 2020

Enhanced inhibitory effect of the matrix metalloproteinase inhibitor Ro 28-2653 in combination with estramustine and etoposide on the prostate carcinoma in the rat Dunning orthotopic tumor model

scientific article published on 7 June 2006

Enzyme activities in urine: how should we express their excretion? A critical literature review

scientific article published on November 1, 1991

Epithelial-mesenchymal transition-associated microRNA/mRNA signature is linked to metastasis and prognosis in clear-cell renal cell carcinoma.

scientific article published on 23 August 2016

Errors in the determination of gamma-glutamyltransferase activity: effects of measurement temperature, pH value and ionic strength on the absorption of 4-nitraniline and 5-amino-2-nitrobenzoate

scientific article published on February 1, 1979

European and US publications in the 50 highest ranking pathology journals from 2000 to 2006

scientific article published on 30 August 2007

Evaluation of Magnetic Fluid Hyperthermia in a Standard Rat Model of Prostate Cancer

scientific article published on 01 June 2004

Evaluation of methods for determining N-acetyl-beta-D-glucosaminidase in urine of rats without purification of urine samples

scientific article published on January 1, 1991

Exchange of different phosphatidylcholine molecular species by phospholipid exchange protein of rat liver

scientific article published on March 1977

Excretion of matrix metalloproteinases 2 and 9 in urine is associated with a high stage and grade of bladder carcinoma

scientific article published on April 2001

Excretion of urinary enzymes after extracorporeal shock wave lithotripsy: a critical reevaluation.

scientific article published in June 1993

Expression and regulation of prostate androgen regulated transcript-1 (PART-1) and identification of differential expression in prostatic cancer.

scientific article

Expression of cathepsins B, H, and L and their inhibitors as markers of transitional cell carcinoma of the bladder

scientific article published on June 2004

Expression of endothelial factors in prostate cancer: a possible role of caveolin-1 for tumour progression

scientific article published on 09 November 2011

Expression of human Kallikrein 14 (KLK14) in breast cancer is associated with higher tumour grades and positive nodal status

scientific article

Expression of the ELAV-like protein HuR in human prostate carcinoma is an indicator of disease relapse and linked to COX-2 expression.

scientific article published on February 2008

Expression of the normal epithelial cell-specific 1 (NES1; KLK10) candidate tumour suppressor gene in normal and malignant testicular tissue

scientific article

Factors influencing the ratio of free to total prostate-specific antigen in serum

scientific article published on 01 December 1997

Fatty acid binding proteins (FABPs) in prostate, bladder and kidney cancer cell lines and the use of IL-FABP as survival predictor in patients with renal cell carcinoma

scientific article

Feedback networks between microRNAs and epigenetic modifications in urological tumors.

scientific article published on April 2012

Free PSA forms in prostatic tissue and sera of prostate cancer patients: analysis by 2-DE and western blotting of immunopurified samples.

scientific article published on 13 January 2007

Further evidence for tubular dysfunction in insulin dependent diabetes

article

GOLPH2 expression in renal cell cancer

scientific article

GOLPH2 protein expression as a novel tissue biomarker for prostate cancer: implications for tissue-based diagnostics

scientific article published on September 2008

Gegendarstellung zu: PSA‑Screening

Gene expression studies in prostate cancer tissue: which reference gene should be selected for normalization?

scientific article published on 7 October 2005

Gene promoter methylation and its potential relevance in early prostate cancer diagnosis

scientific article published on 29 November 2010

Germ cell tumors of the gonads: a selective review emphasizing problems in drug resistance and current therapy options

scientific article published on 20 December 2008

Glutathione S-transferase-pi protein expression in prostate cancer--not always a useful diagnostic tool

Glutathione S-transferase-pi protein expression in prostate cancer-not always a useful diagnostic tool

Heparin affects matrix metalloproteinases and tissue inhibitors of metalloproteinases circulating in peripheral blood

scientific article published on 02 October 2008

Hepsin is highly over expressed in and a new candidate for a prognostic indicator in prostate cancer

scientific article

High expression of KLK14 in prostatic adenocarcinoma is associated with elevated risk of prostate-specific antigen relapse

scientific article

High-grade acute organ toxicity as a positive prognostic factor in primary radiochemotherapy for anal carcinoma.

scientific article published on 3 June 2010

High-grade acute organ toxicity as positive prognostic factor in adjuvant radiation and chemotherapy for locally advanced head and neck cancer

scientific article published on March 2011

High-grade acute organ toxicity as positive prognostic factor in primary radio(chemo)therapy for locally advanced, inoperable head and neck cancer

scientific article published on 26 April 2010

High-grade acute organ toxicity during preoperative radiochemotherapy as positive predictor for complete histopathologic tumor regression in multimodal treatment of locally advanced rectal cancer

scientific article published on 28 December 2009

Histone deacetylases 1, 2 and 3 are highly expressed in prostate cancer and HDAC2 expression is associated with shorter PSA relapse time after radical prostatectomy

scientific article published on 22 January 2008

INFLUENCE OF PRESERVATION SOLUTIONS ON LIPID PEROXIDATION AND MITOCHONDRIAL RESPIRATION IN RAT KIDNEYS

scientific article published on 01 May 1990

Identification and characterization of a novel human testis-specific kinase substrate gene which is downregulated in testicular tumors

scientific article published in July 2001

Identification and validation of suitable endogenous reference genes for gene expression studies of human bladder cancer.

scientific article published in May 2006

Identification of a DNA methylation signature to predict disease-free survival in locally advanced rectal cancer.

scientific article

Identification of metastamirs as metastasis-associated microRNAs in clear cell renal cell carcinomas

scientific article

Identification of microRNAs in blood and urine as tumour markers for the detection of urinary bladder cancer.

scientific article published on 18 July 2013

Identification of single nucleotide polymorphisms in the human kallikrein 10 (KLK10) gene and their association with prostate, breast, testicular, and ovarian cancers

scientific article (publication date: April 2002)

Identification of stanniocalcin 2 as prognostic marker in renal cell carcinoma.

scientific article

Impact of Blood Sampling on Circulating Tissue Inhibitors of Metalloproteinases

scientific article published on 01 April 2006

Impact of Blood Sampling on the Circulating Matrix Metalloproteinases 1, 2, 3, 7, 8, and 9

scientific article published on 01 April 2008

Impact of RNA degradation on gene expression profiling.

scientific article

Impact of distant metastasis in patients with cervical lymph node metastases from cancer of an unknown primary site

scientific article published in September 2009

Importance of brain‑type fatty acid binding protein for cell-biological processes in human renal carcinoma cells.

scientific article published on 8 March 2011

Improved prostate cancer detection with a human kallikrein 11 and percentage free PSA-based artificial neural network.

scientific article published in June 2006

In search of suitable reference genes for gene expression studies of human renal cell carcinoma by real-time PCR.

scientific article published on 8 June 2007

In situ gene expression and localization of metalloproteinases MMP1, MMP2, MMP3, MMP9, and their inhibitors TIMP1 and TIMP2 in human renal cell carcinoma.

scientific article published in May 2006

In situ gene expression of urokinase-type plasminogen activator and its receptor in transitional cell carcinoma of the human bladder.

scientific article published in October 2004

Increased CD59 protein expression predicts a PSA relapse in patients after radical prostatectomy.

scientific article published in February 2005

Increased Creatine Kinase BB Activity in Rat Plasma Induced by Hypoxia

scientific article published on 01 January 1980

Increased analytical sensitivity of RT-PCR of PSA mRNA decreases diagnostic specificity of detection of prostatic cells in blood.

scientific article

Increased cell-free DNA in plasma of patients with metastatic spread in prostate cancer

scientific article published in March 2004

Increased mRNA expression of ADAMs in renal cell carcinoma and their association with clinical outcome.

scientific article published in February 2004

Increased production of matrix metalloproteinase-2 in alveolar macrophages and regulation by interleukin-10 in patients with acute pulmonary sarcoidosis.

scientific article published in January 2002

Increased serum γ-glutamyltransferase activity in renal transplant recipients: liver damage or microsomal enzyme induction?

scientific article published on 01 August 1984

Influence of Mg^2+ Ions on the Activity Measurement of Isoenzymes of Alkaline Phosphatase

scientific article published on 01 January 1979

Influence of cyclosporin A on the respiration of isolated rat kidney mitochondria

scientific article published on 01 April 1985

Influence of inorganic phosphate on the activity determination of isoenzymes of alkaline phosphatase in various buffer systems

scientific article published on 01 March 1980

Influence of irradiated lung volumes on perioperative morbidity and mortality in patients after neoadjuvant radiochemotherapy for esophageal cancer

scientific article published on 11 August 2009

Inhibited efficiency of kidney mitochondria isolated from rats treated with cyclosporin A

scientific article published on 01 January 1987

Inhibiting WNT and NOTCH in renal cancer stem cells and the implications for human patients

scientific article published on 17 February 2020

Instability of circular RNAs in clinical tissue samples impairs their reliable expression analysis using RT-qPCR: from the myth of their advantage as biomarkers to reality

scientific article published on 23 July 2020

Integrated microRNA and mRNA Signature Associated with the Transition from the Locally Confined to the Metastasized Clear Cell Renal Cell Carcinoma Exemplified by miR-146-5p

scientific article published on 9 February 2016

Integration of tissue metabolomics, transcriptomics and immunohistochemistry reveals ERG- and gleason score-specific metabolomic alterations in prostate cancer

scientific article published on 23 November 2015

Interchangeability of measurements of total and free prostate-specific antigen in serum with 5 frequently used assay combinations: an update.

scientific article published in January 2006

Internal validation of an artificial neural network for prostate biopsy outcome.

scientific article

Intron retention: a common splicing event within the human kallikrein gene family

scientific article published on 13 January 2005

Is NF-κB predictive of biochemical recurrence in positive-margin prostate cancer?

scholarly article by Carsten Stephan et al published March 2005 in Nature Reviews Urology

Is serum matrix metalloproteinase 9 a useful biomarker in detection of colorectal cancer? Considering pre-analytical interference that may influence diagnostic accuracy

scientific article published on 22 July 2008

Is there an optimal prostate-specific antigen threshold for prostate biopsy?

scientific article published in August 2011

Ischemia decreases the content of the adenine nucleotide translocator in mitochondria of rat kidney.

scientific article published in January 1991

Ischemia-induced alterations of rat kidney mitochondria

scientific article published in May 1990

Isoforms of prostate-specific antigen in serum: A result of the glycosylation process in dysplastic prostatic cells?

scientific article published on 01 July 1996

KDM5C is overexpressed in prostate cancer and is a prognostic marker for prostate-specific antigen-relapse following radical prostatectomy

scientific article

KLK15 is a prognostic marker for progression-free survival in patients with radical prostatectomy

scientific article

KRAS and BRAF mutations in patients with rectal cancer treated with preoperative chemoradiotherapy.

scientific article published on 11 November 2009

Karyopherin Alpha 2 Is an Adverse Prognostic Factor in Clear-Cell and Papillary Renal-Cell Carcinoma

scientific article published on 23 October 2018

LETTERS TO THE EDITOR

scientific article published on 01 February 2002

Laser-induced hyperthermia in rat prostate cancer: role of site of tumor implantation.

scientific article

Lecithin: Cholesterol Acyltransferase Activity, HDL-Cholesterol and Apolipoprotein A in Serum of Patients Undergoing Chronic Haemodialysis

scientific article published on 01 January 1980

Lecithin: cholesterol acyltransferase activity in patients with chronic liver diseases and positive LP-X tests

scientific article published on January 1978

LecithiniCholesterol Acyltransferase Activity and HDL Composition in Serum of Patients with Kidney Transplants

article

Limited utility of qPCR-based detection of tumor-specific circulating mRNAs in whole blood from clear cell renal cell carcinoma patients

scientific article published on 04 February 2020

Long-Term Stability of Enzymes in Human Serum Stored in Liquid Nitrogen

scientific article published on 01 January 1984

Loss of SLC45A3 protein (prostein) expression in prostate cancer is associated with SLC45A3-ERG gene rearrangement and an unfavorable clinical course.

scientific article published on 30 August 2012

Loss of cadherin related family member 5 (CDHR5) expression in clear cell renal cell carcinoma is a prognostic marker of disease progression.

scientific article published on 24 August 2017

Loss of the tissue-specific proapoptotic BH3-only protein Nbk/Bik is a unifying feature of renal cell carcinoma.

scientific article

Low-Molecular-Mass Proteins in Serum and Their Relationship to the Glomerular Filtration Rate

scientific article published on 01 January 1987

Lower serum high-density lipoprotein-cholesterol concentration in patients undergoing maintenance hemodialysis with acetate than with bicarbonate

scientific article published on 01 April 1995

Lymphatic micrometastases predict biochemical recurrence in patients undergoing radical prostatectomy and pelvic lymph node dissection for prostate cancer

scientific article published on 21 March 2019

Magnetic fluid hyperthermia (MFH)reduces prostate cancer growth in the orthotopic Dunning R3327 rat model.

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Metabolic profiling reveals key metabolic features of renal cell carcinoma

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Metalloproteinases and Tissue Inhibitors of Matrix-Metalloproteinases in Plasma of Patients with Prostate Cancer and in Prostate Cancer Tissue

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Methods Compared for Determining Activity of N-Acetyl-β-D-Glucosaminidase in Urine without Pretreatment of Sample: Different Sensitivity and Species Effect

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Mikro-RNA in der Uroonkologie

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Misinterpretation of quantitative RT-PCR results: A comment on the article by Ohashi et al. “RNA degradation in human breast tissue after surgical removal: a time course study”, Exp. Mol. Pathol. 77 (2004) 98–103

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Molecular Cloning of a New Gene Which Is Differentially Expressed in Breast and Prostate Cancers

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Multiple forms of N-acetyl-beta-D-glucosaminidase of human urine: isolation, properties and the development of a practical approach of differentiation

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Plasma But Not Serum Should Be Used for Determining Tissue Inhibitor of Metalloproteinase in Blood

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Plasma matrix metalloproteinase-7 as a metastatic marker and survival predictor in patients with renal cell carcinomas

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Plasma miR‑15b‑5p and miR‑590‑5p for distinguishing patients with bladder cancer from healthy individuals

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Plasma osteopontin in comparison with bone markers as indicator of bone metastasis and survival outcome in patients with prostate cancer.

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Polo-like kinase 1 is overexpressed in prostate cancer and linked to higher tumor grades

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Polymerase chain reaction in the detection of micrometastases and circulating tumor cells

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Practical approach for determining glomerular filtration rate by single-injection inulin clearance ⬇️

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Pre-analytical conditions for the assessment of circulating MMP-9 and TIMP-1: consideration of pitfalls

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Preanalytical Interferences Compromise the Clinical Validity of Matrix Metalloproteinase 1 as Marker of Colorectal Cancer

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Preanalytical pitfalls of blood sampling to measure true circulating matrix metalloproteinase 9 and tissue inhibitors of matrix metalloproteinases

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Prognostic relevance of proliferation markers (Ki-67, PHH3) within the cross-relation of ERG translocation and androgen receptor expression in prostate cancer

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Prostate cancer screening with prostate-specific antigen testing: more answers or more confusion?

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Prostate specific antigen density to predict prostate cancer upgrading in a contemporary radical prostatectomy series: a single center experience.

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Prostate-specific antigen and other serum and urine markers in prostate cancer.

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Proteomic analysis of conditioned media from the PC3, LNCaP, and 22Rv1 prostate cancer cell lines: discovery and validation of candidate prostate cancer biomarkers

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Punicalagin, a polyphenol from pomegranate fruit, induces growth inhibition and apoptosis in human PC-3 and LNCaP cells

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Quality control material for activity determinations of urinary enzymes

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Quantitative analysis of kallikrein 15 gene expression in prostate tissue

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Quantitative analysis of macrophage inhibitory cytokine-1 (MIC-1) gene expression in human prostatic tissues

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Quantitative differences in matrix metalloproteinase (MMP)-2, but not in MMP-9, tissue inhibitor of metalloproteinase (TIMP)-1 or TIMP-2, in seminal plasma of normozoospermic and azoospermic patients.

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RATIO OF FREE-TO-TOTAL PROSTATE SPECIFIC ANTIGEN IN SERUM CANNOT DISTINGUISH PATIENTS WITH PROSTATE CANCER FROM THOSE WITH CHRONIC INFLAMMATION OF THE PROSTATE

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Re: A molecular correlate to the Gleason grading system for prostate adenocarcinoma.

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Re: Al-Azab R, Toi A, Lockwood G, et al. Prostate Volume Is Strongest Predictor of Cancer Diagnosis at Transrectal Ultrasound-Guided Prostate Biopsy with Prostate-Specific Antigen Values Between 2.0 and 9.0 ng/mL (Urology 69:103-107, 2007)

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Re: Application of artificial intelligence to the management of urological cancer. M. F. Abbod, J. W. Catto, D. A. Linkens and F. C. Hamdy J Urol 2007; 178: 1150-1156.

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Re: Editorial: Can Prostate Specific Antigen Derivatives Reduce the Frequency of Unnecessary Prostate Biopsies?

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Re: Felix K.-H. Chun, Markus Graefen, Alberto Briganti, Andrea Gallina, Julia Hopp, Michael W. Kattan, Hartwig Huland and Pierre I. Karakiewicz. Initial biopsy outcome prediction--head-to-head comparison of a logistic regression-based nomogram versu

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Re: Free and complexed prostate specific antigen in the differentiation of benign prostatic hyperplasia and prostate cancer: studies in serum and plasma samples

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Re: Hessels D, Klein Gunnewiek JMT, van Oort I, Karthaus HFM, van Leenders GJL, van Balken B, Kiemeney LA, Witjes JA, Schalken JA. DD3PCA3-based molecular urine analysis for the diagnosis of prostate cancer. Eur Urol 2003;44:8?16

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Re: MicroRNA regulation of oncolytic herpes simplex virus-1 for selective killing of prostate cancer cells

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Re: Roddam AW, Duffy MJ, Hamdy FC, et al. Use of Prostate-Specific Antigen (PSA) Isoforms for the Detection of Prostate Cancer in Men with a PSA Level of 2–10ng/ml: Systematic Review and Meta-Analysis. Eur Urol 2005;48:386–99

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Re: Scott A. Tomlins, John R. Day, Robert J. Lonigro, et al. Urine TMPRSS2:ERG Plus PCA3 for Individualized Prostate Cancer Risk Assessment. Eur Urol. In press. http://dx.doi.org/10.1016/j.eururo.2015.04.039.

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Re: Serum Vitamin D is Not Helpful for Predicting Prostate Cancer Aggressiveness Compared with the Prostate Health Index: C. Stephan, M. Lein, J. Matalon, E. Kilic, Z. Zhao, J. Busch and K. Jung J Urol 2016;196:709-714

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Re: a prospective study to evaluate the role of complexed prostate specific antigen and free/total prostate specific antigen ratio for the diagnosis of prostate cancer. I.D.C. Mitchell, B.L. Croal, A. Dickie, N.P. Cohen and I. Ross. J Urol, 165: 154

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Reduced serum selenoprotein P concentrations in German prostate cancer patients.

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Reference genes for the relative quantification of microRNAs in renal cell carcinomas and their metastases.

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Reference intervals for α1-microglobulin in urine

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Reference miRNAs for miRNAome analysis of urothelial carcinomas

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Refinements of assays for low concentrations of inulin in serum

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Relation of free PSA/total PSA in serum for differentiating between patients with prostatic cancer and benign hyperplasia of the prostate: which cutoff should be used?

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Relationship between semen quality and the seminal plasma components carnitine, alpha-glucosidase, fructose, citrate and granulocyte elastase in infertile men compared with a normal population

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Relative Stimulation of Aspartate Aminotransferase Activity in Human Serum by Pyridoxal 5'-Phosphate in Myocardial Infarction

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Renal cell neoplasias: reversion-inducing cysteine-rich protein with Kazal motifs discriminates tumor subtypes, while extracellular matrix metalloproteinase inducer indicates prognosis

scientific article published on 16 October 2013

Renal oncocytoma characterized by the defective complex I of the respiratory chain boosts the synthesis of the ROS scavenger glutathione

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Repeating the measurement of prostate-specific antigen in symptomatic men can avoid unnecessary prostatic biopsy

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Reply from Authors re: Jack A. Schalken. Is Urinary Sarcosine Useful to Identify Patients With Significant Prostate Cancer? The Trials and Tribulations of Biomarker Development. Eur Urol 2010;58:19–20

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Reply to Amitha K Hewavitharana’s Letter to the Editor re: Florian Jentzmik, Carsten Stephan, Kurt Miller, et al. Sarcosine in Urine After Digital Examination Fails as a Marker in Prostate Cancer Detection and Identification of Aggressive Tumours.

Reply to C.J. Shukla, Dylan Edwards and Krishna K. Sethia’s Letter to the Editor re: Anja Rabien, Mick Burkhardt, Monika Jung, Florian Fritzsche, Martin Ringsdorf, Hanka Schicktanz, Stefan A. Loening, Glen Kristiansen and Klaus Jung. Decreased RECK

Reporting FDR analogous confidence intervals for the log fold change of differentially expressed genes. ⬇️

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Risk prediction models for biochemical recurrence after radical prostatectomy using prostate-specific antigen and Gleason score

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Robust microRNA stability in degraded RNA preparations from human tissue and cell samples

scientific article published on 8 April 2010

S100A8, S100A9, and the S100A8/A9 complex in circulating blood are not associated with prostate cancer risk—A re-evaluation study

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SHORT COMMUNICATION

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Sample processing and its preanalytical impact on the measurement of circulating matrix metalloproteinases

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Sarcosine in prostate cancer tissue is not a differential metabolite for prostate cancer aggressiveness and biochemical progression.

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Sarcosine in urine after digital rectal examination fails as a marker in prostate cancer detection and identification of aggressive tumours

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Selenoprotein P status correlates to cancer-specific mortality in renal cancer patients.

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Sensitivity of HOXB13 as a Diagnostic Immunohistochemical Marker of Prostatic Origin in Prostate Cancer Metastases: Comparison to PSA, Prostein, Androgen Receptor, ERG, NKX3.1, PSAP, and PSMA.

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Sequential interim analyses of survival data in DNA microarray experiments ⬇️

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Serial Markers of Bone Turnover in Men with Metastatic Prostate Cancer Treated with Zoledronic Acid for Detection of Bone Metastases Progression

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Serum (-5, -7) proPSA for distinguishing stage and grade of prostate cancer.

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Serum Vitamin D is Not Helpful for Predicting Prostate Cancer Aggressiveness Compared with the Prostate Health Index.

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Serum amyloid A as indicator of distant metastases but not as early tumor marker in patients with renal cell carcinoma.

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Serum human glandular kallikrein 2 (hK2) for distinguishing stage and grade of prostate cancer

Serum macrophage migration inhibitory factor is not elevated in patients with prostate cancer

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Serum or plasma: What kind of blood sample should be used to measure circulating matrix metalloproteinases and their inhibitors?

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Serum osteoprotegerin and receptor activator of nuclear factor-kappa B ligand as indicators of disturbed osteoclastogenesis in patients with prostate cancer.

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Serum samples are inappropriate for use in measuring circulating matrix metalloproteinases: Comment on the article by Young-Min et al

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Serum testosterone improves the accuracy of Prostate Health Index for the detection of prostate cancer

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Soluble CD44 molecules in serum of patients with prostate cancer and benign prostatic hyperplasia

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Synthetic inhibitor of matrix metalloproteinases (batimastat) reduces prostate cancer growth in an orthotopic rat model

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TMPRSS2-ERG fusion transcripts in matched urine and needle rinse material after biopsy for the detection of prostate cancer: really a step forward?

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TRPM4 protein expression in prostate cancer: a novel tissue biomarker associated with risk of biochemical recurrence following radical prostatectomy.

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The Immune Checkpoint Regulator PD-L1 Is Highly Expressed in Aggressive Primary Prostate Cancer

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The androgen-regulated Calcium-Activated Nucleotidase 1 (CANT1) is commonly overexpressed in prostate cancer and is tumor-biologically relevant in vitro.

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The antiapoptotic function of miR-96 in prostate cancer by inhibition of FOXO1

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The apoenzyme of aspartate aminotransferase and alanine aminotransferase in the serum of healthy persons and patients suffering from liver diseases

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The discriminative ability of Prostate Health Index to detect prostate cancer is enhanced in combination with miR-222-3p

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The influence of prostate volume on the ratio of free to total prostate specific antigen in serum of patients with prostate carcinoma and benign prostate hyperplasia

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The kallikrein gene 5 splice variant 2 is a new biomarker for breast and ovarian cancer

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The membrane proteases adams and hepsin are differentially expressed in renal cell carcinoma. Are they potential tumor markers?

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The miRNA-kallikrein axis of interaction: a new dimension in the pathogenesis of prostate cancer.

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The new synthetic matrix metalloproteinase inhibitor (Roche 28-2653) reduces tumor growth and prolongs survival in a prostate cancer standard rat model

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The novel synthetic inhibitor of matrix metalloproteinases Ro 28-2653 induces apoptosis in Dunning tumor cells

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The percentage of prostate-specific antigen (PSA) isoform [-2]proPSA and the Prostate Health Index improve the diagnostic accuracy for clinically relevant prostate cancer at initial and repeat biopsy compared with total PSA and percentage free PSA i

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The prostate health index PHI predicts oncological outcome and biochemical recurrence after radical prostatectomy - analysis in 437 patients

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The ratio of free to total prostate-specific antigen in serum is correlated to the prostate volume

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The ratio of prostate-specific antigen (PSA) to prostate volume (PSA density) as a parameter to improve the detection of prostate carcinoma in PSA values in the range of < 4 ng/mL.

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The translational potential of microRNAs as biofluid markers of urological tumours.

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The way of prostate cancer diagnostics

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Thermotherapy using magnetic nanoparticles combined with external radiation in an orthotopic rat model of prostate cancer.

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Thiosulfate in urine: new hope or new failure of a biomarker for prostate cancer?

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Tissue inhibitors of metalloproteinases 1 and 2 in human seminal plasma and their association with spermatozoa.

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Tissue metabolite profiling identifies differentiating and prognostic biomarkers for prostate carcinoma

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Tissue-Based MicroRNAs as Predictors of Biochemical Recurrence after Radical Prostatectomy: What Can We Learn from Past Studies?

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Toward metrological traceability in the determination of prostate-specific antigen (PSA): calibrating Beckman Coulter Hybritech Access PSA assays to WHO standards compared with the traditional Hybritech standards.

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Tumoural CXCL16 expression is a novel prognostic marker of longer survival times in renal cell cancer patients

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Two-Dimensional Electrophoresis in Prostate Cancer Research and Diagnostics

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Urinary miR-183 and miR-205 do not surpass PCA3 in urine as predictive markers for prostate biopsy outcome despite their highly dysregulated expression in prostate cancer tissue

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mRNA expression profile of matrix metalloproteinases and their tissue inhibitors in malignant and non-malignant prostatic tissue

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miR-199a-3p and miR-214-3p improve the overall survival prediction of muscle-invasive bladder cancer patients after radical cystectomy

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miR-9-5p in Nephrectomy Specimens is a Potential Predictor of Primary Resistance to First-Line Treatment with Tyrosine Kinase Inhibitors in Patients with Metastatic Renal Cell Carcinoma

miRNA panels as biomarkers for bladder cancer.

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miRNA profiling identifies candidate mirnas for bladder cancer diagnosis and clinical outcome

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miRNAs can predict prostate cancer biochemical relapse and are involved in tumor progression.

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miRNAs dysregulated in association with Gleason grade regulate extracellular matrix, cytoskeleton and androgen receptor pathways.

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