Search filters

List of works by Alberto Izzotti

A Global MicroRNA Profile in Fanconi Anemia: A Pilot Study

scientific article published on 30 October 2018

A novel calix[4]pyrrole derivative as a potential anticancer agent that forms genotoxic adducts with DNA

scientific article published on 23 July 2018

Ability of dorzolamide hydrochloride and timolol maleate to target mitochondria in glaucoma therapy.

scientific article published on January 2011

Accelerated repair and reduced mutagenicity of DNA damage induced by cigarette smoke in human bronchial cells transfected with E.coli formamidopyrimidine DNA glycosylase.

scientific article published on 31 January 2014

Age-related increases of 8-hydroxy-2'-deoxyguanosine and DNA-protein crosslinks in mouse organs

scientific article published on 01 December 1999

Aicardi-Goutieres syndrome, a rare neurological disease in children: a new autoimmune disorder?

scientific article

Alterations of gene expression in skin and lung of mice exposed to light and cigarette smoke.

scientific article

Antioxidant activity of timolol on endothelial cells and its relevance for glaucoma course.

scientific article published on 9 February 2007

Aqueous humor oxidative stress proteomic levels in primary open angle glaucoma.

scientific article

Assay of lapatinib in murine models of cigarette smoke carcinogenesis.

scientific article

Benzo[a]pyrene diolepoxide-DNA adducts in alveolar macrophages of smokers.

scientific article published in July 1991

Biological monitoring of Italian soldiers deployed in Iraq. Results of the SIGNUM project

scientific article published on 4 August 2015

Biphosphonates-associated osteonecrosis of the jaw: the role of gene-environment interaction

scientific article

Blood and lung microRNAs as biomarkers of pulmonary tumorigenesis in cigarette smoke-exposed mice.

scientific article published on 05 October 2016

Brain damage as detected by cDNA-microarray in the spinal fluid of patients with Aicardi-Goutieres syndrome.

scientific article published on 2 July 2008

Brain microglia activation induced by intracranial administration of oligonucleotides and its pharmacological modulation

scientific article published on 01 October 2018

Can Polyphenols in Eye Drops Be Useful for Trabecular Protection from Oxidative Damage?

scientific article published on 06 November 2020

Cancer biomarkers in human atherosclerotic lesions: detection of DNA adducts.

scientific article published in March 1995

Carcinogen-DNA adducts in human alveolar macrophages.

scientific article

Chemoprevention of carcinogen-DNA adducts and chronic degenerative diseases.

scientific article

Chemoprevention of genome, transcriptome, and proteome alterations induced by cigarette smoke in rat lung.

scientific article published in September 2005

Chemoprevention of smoke-related DNA adduct formation in rat lung and heart.

scientific article published in November 1992

Cytosolic activation of aromatic and heterocyclic amines. Inhibition by dicoumarol and enhancement in viral hepatitis B

scientific article

DNA adducts and chronic degenerative disease. Pathogenetic relevance and implications in preventive medicine.

scientific article published in December 1996

DNA alterations in rat organs after chronic exposure to cigarette smoke and/or ethanol ingestion ⬇️

scientific article published on June 1, 1998

DNA damage and alterations of gene expression in chronic-degenerative diseases.

scientific article

DNA damage, mutagenesis and cardiovascular disease

scientific article published on 28 February 2007

DNA fragmentation, DNA-protein crosslinks, postlabeled nucleotidic modifications, and 8-hydroxy-2'-deoxyguanosine in the lung but not in the liver of rats receiving intratracheal instillations of chromium(VI). Chemoprevention by oral N-acetylcystein

scientific article

Dental implants osteogenic properties evaluated by cDNA microarrays.

scientific article

Detection of the '4977 bp' mitochondrial DNA deletion in human atherosclerotic lesions

scientific article published on 01 January 1999

Different mutations in three prime repair exonuclease 1 and ribonuclease H2 genes affect clinical features in Aicardi-Goutieres syndrome.

scientific article published on 23 August 2011

Dose-responsiveness and persistence of microRNA expression alterations induced by cigarette smoke in mouse lung ⬇️

scientific article published on December 24, 2010

Drug metabolism polymorphisms as modulators of cancer susceptibility.

scientific article

Duration of exposure to environmental carcinogens affects DNA-adduct level in human lymphocytes

scientific article published on 14 September 2010

Early and late effects of aspirin and naproxen on microRNAs in the lung and blood of mice, either unexposed or exposed to cigarette smoke.

scientific article published on 24 August 2017

Effects of oral administration of N-acetyl-L-cysteine: a multi-biomarker study in smokers.

scientific article published in February 2002

Enhanced levels of DNA adducts in the liver of woodchucks infected with hepatitis virus.

scientific article

Environmental carcinogens and mutational pathways in atherosclerosis

scientific article published on 7 February 2015

Environmental light and endogenous antioxidants as the main determinants of non-cancer ocular diseases ⬇️

scientific article published on January 19, 2013

Etoposide-resistance in a neuroblastoma model cell line is associated with 13q14.3 mono-allelic deletion and miRNA-15a/16-1 down-regulation

scientific article published in Scientific Reports

Ex vivo study for the assessment of behavioral factor and gene polymorphisms in individual susceptibility to oxidative DNA damage metals-induced

scientific article published on 22 February 2011

Exposing native cyprinid (Barbus plebejus) juveniles to river sediments leads to gonadal alterations, genotoxic effects and thyroid disruption

scientific article

Exposure to PAHs, urinary 1-pyrenol and DNA adducts in samples from a population living at different distances from a steel plant

scientific article published in July 2003

Extracellular MicroRNA in liquid biopsy: applicability in cancer diagnosis and prevention

scientific article

Focus on molecular events in the anterior chamber leading to glaucoma.

scientific article

Formation and persistence of nucleotide alterations in rats exposed whole-body to environmental cigarette smoke

scientific article published on 01 August 1999

Formation of DNA adducts in the aorta of smoke-exposed rats, and modulation by chemopreventive agents.

scientific article published in July 2001

From DNA damage to functional changes of the trabecular meshwork in aging and glaucoma

scientific article published on 27 May 2016

Gene expression and genotoxicity in Manila clam (Ruditapes philippinarum) modulated by sediment contamination and lagoon dynamics in the Po river delta

article

Gene expression in the lung of p53 mutant mice exposed to cigarette smoke.

scientific article published on December 2004

Gene-environment interactions in non-cancer degenerative diseases

scientific article published on 09 June 2009

Gene-environment interactions in ocular diseases.

scientific article

Genomic and post-genomic effects of anti-glaucoma drugs preservatives in trabecular meshwork.

scientific article

Genomic and transcriptional alterations in mouse fetus liver after transplacental exposure to cigarette smoke ⬇️

scientific article published on April 22, 2003

Genomic biomarkers and clinical outcomes of physical activity.

scientific article published on July 2011

Glaucomatous outflow pathway and oxidative stress.

scientific article published on 29 December 2006

Glutathione S-transferase M1 and its implications in glaucoma pathogenesis: a controversial matter.

scientific article

Glutathione-mediated antioxidant response and aerobic metabolism: two crucial factors involved in determining the multi-drug resistance of high-risk neuroblastoma.

scientific article published on 23 September 2016

Helicobacter pylori infection and eye diseases: a systematic review.

scientific article

Helicobacter pylori, oxidative stress and glaucoma

scientific article published on 19 June 2012

Human Papillomavirus Infections, Cervical Cancer and MicroRNAs: An Overview and Implications for Public Health

scientific article published on 26 October 2019

Human primary endothelial cells are impaired in nucleotide excision repair and sensitive to benzo[a]pyrene compared with smooth muscle cells and pericytes

scientific article published on 24 September 2019

In vitro inhibition by N-acetylcysteine of oxidative DNA modifications detected by 32P postlabeling

scientific article published on 01 February 1998

Increased resistance to oxidative DNA damage of trabecular meshwork cells by E. coli FPG gene transfection.

scientific article published on 11 May 2011

Indoor pollution and burning practices in wood stove management

scientific article published on November 2014

Induction and modulation of lung tumors: genomic and transcriptional alterations in cigarette smoke-exposed mice.

scientific article

Induction by carcinogens and chemoprevention by N-acetylcysteine of adducts to mitochondrial DNA in rat organs

scientific article published on 01 April 1996

Induction of apoptosis in the lung but not in the liver of rats receiving intra-tracheal instillations of chromium(VI)

scientific journal article

Induction of micronuclei in cultured human lymphocytes exposed to quartz halogen lamps and its prevention by glass covers

scientific article published on 01 January 1993

Inherent and toxicant-provoked reduction in DNA repair capacity: A key mechanism for personalized risk assessment, cancer prevention and intervention, and response to therapy

scientific article published on 21 July 2018

Inhibition by N-acetylcysteine of carcinogen-DNA adducts in the tracheal epithelium of rats exposed to cigarette smoke

scientific article published on 01 March 1995

Inhibition of neuroblastoma cell growth by TREX1-mutated human lymphocytes.

scientific article

Inhibition of the de-myelinating properties of Aicardi-Goutières syndrome lymphocytes by cathepsin D silencing.

scientific article

Interaction between Helicobacter pylori, diet, and genetic polymorphisms as related to non-cancer diseases.

scientific article published on 14 February 2009

Interferon-related transcriptome alterations in the cerebrospinal fluid cells of Aicardi-Goutières patients

scientific article published on 23 October 2008

Interplay between Helicobacter pylori and host gene polymorphisms in inducing oxidative DNA damage in the gastric mucosa.

scientific article published on 24 November 2006

Interplay between histopathological alterations, cigarette smoke and chemopreventive agents in defining microRNA profiles in mouse lung.

scientific article published on 23 October 2010

K-ras mutations in lung tumors from p53 mutant mice exposed to cigarette smoke

scientific article published on 01 March 2005

Lipid peroxidation-derived etheno-DNA adducts in human atherosclerotic lesions

scientific article published on 02 March 2007

Mechanisms of antimutagenesis and anticarcinogenesis: role in primary prevention.

scientific article published on January 1993

Methodology for evaluating oxidative DNA damage and metabolic genotypes in human trabecular meshwork.

scientific article published in January 2003

MicroRNAs as targets for dietary and pharmacological inhibitors of mutagenesis and carcinogenesis

scientific article

MicroRNAs in cancer treatment and prognosis.

scientific article published on 28 June 2012

MicroRNAs: modulators of cell identity, and their applications in tissue engineering

scientific article

Mitochondrial damage in the trabecular meshwork occurs only in primary open-angle glaucoma and in pseudoexfoliative glaucoma

scientific article

Mitochondrial damage in the trabecular meshwork of patients with glaucoma.

scientific article published in June 2010

Modulation by aspirin and naproxen of nucleotide alterations and tumors in the lung of mice exposed to environmental cigarette smoke since birth

scientific article

Modulation by metformin of molecular and histopathological alterations in the lung of cigarette smoke-exposed mice

scientific article

Modulation of genomic and epigenetic end-points by celecoxib

scientific article published on 14 September 2018

Modulation of genomic and postgenomic alterations in noncancer diseases and critical periods of life.

scientific article published on 02 October 2008

Modulation of microRNA expression by budesonide, phenethyl isothiocyanate and cigarette smoke in mouse liver and lung

scientific article

Modulation of smoke-induced DNA and microRNA alterations in mouse lung by licofelone, a triple COX-1, COX-2 and 5-LOX inhibitor

scientific article published on 01 March 2020

Molecular Damage in Glaucoma: from Anterior to Posterior Eye Segment. The MicroRNA Role

scientific article published on 07 July 2015

Molecular and cytogenetical alterations induced by environmental cigarette smoke in mice heterozygous for Fhit

scientific article published on 01 February 2007

Molecular damage and lung tumors in cigarette smoke-exposed mice.

scientific article

Molecular diagnostics of ocular diseases: the application of antibody microarray ⬇️

scientific article published on July 1, 2012

Molecular epidemiology in cancer research (review).

scientific article

Molecular epidemiology of atherosclerosis

scientific article published on 01 October 1997

Molecular fingerprints of environmental carcinogens in human cancer.

scientific article published on April 2015

Molecular medicine and the development of cancer chemopreventive agents.

scientific article published on July 2012

Mutagenesis and cardiovascular diseases Molecular mechanisms, risk factors, and protective factors

scientific article published on 28 February 2007

Mutagenicity of sediments along the Po River and genotoxicity biomarkers in fish from polluted areas.

scientific article published in March 2002

Mutagens interfere with microRNA maturation by inhibiting DICER. An in silico biology analysis.

scientific article

Nanoparticles increase the efficacy of cancer chemopreventive agents in cells exposed to cigarette smoke condensate.

scientific article

New proteins as vascular biomarkers in primary open angle glaucomatous aqueous humor.

scientific article

No effect of treatment with carcinogens on cytosine methylation of mitochondrial DNA isolated from rat organs by phenol-free alkaline extraction

scientific article published on 01 October 1995

Noncoding RNAs: Possible Players in the Development of Fluorosis

scientific article

Open angle glaucoma: epidemiology, pathogenesis and prevention

scientific article published in January 2006

Oxidative DNA damage in the human trabecular meshwork: clinical correlation in patients with primary open-angle glaucoma.

scientific article published in April 2005

Oxidative damage and autophagy in the human trabecular meshwork as related with ageing

scientific article

Patterns of DNA adduct formation in liver and mammary epithelial cells of rats treated with 7,12-dimethylbenz(a)anthracene, and selective effects of chemopreventive agents

scientific article published on 01 September 1999

Pharmacological modulation of genome and proteome alterations in mice treated with the endocrine disruptor bisphenol A.

scientific article published in March 2010

Photoactivation of mutagens.

scientific article published in June 1989

Physical activity and cancer prevention: a review of current evidence and biological mechanisms.

scientific article published on December 2011

Post-mortem stability of benzo[a]pyrene diolepoxide--DNA adducts in rat organs

scientific article published on 01 October 1993

Potent genotoxicity of halogen lamps, compared to fluorescent light and sunlight.

scientific article published in December 1990

Prevention by N-acetylcysteine of benzo[a]pyrene clastogenicity and DNA adducts in rats

scientific article published on 01 September 1991

Prevention of Lymphocyte Neurotoxic Effects by microRNA Delivery.

scientific article published in January 2014

Proteome alterations in primary open angle glaucoma aqueous humor.

scientific article

Proteomic analysis as related to transcriptome data in the lung of chromium(VI)-treated rats.

scientific article published in June 2004

Proteomic-based screening of miRNAs metabolic pathway targeting

scientific article published on 16 September 2010

Public health issues from crude-oil production in the Ecuadorian Amazon territories

scientific article published on 22 November 2019

Pulmonary alveolar macrophages in molecular epidemiology and chemoprevention of cancer

scientific article

Radon Biomonitoring and microRNA in Lung Cancer

scientific article published on 20 March 2020

Rationale and approaches to the prevention of smoking-related diseases: overview of recent studies on chemoprevention of smoking-induced tumors in rodent models

scientific article published on January 2014

Re: The central role of receiver operating characteristic (ROC) curves in evaluating tests for the early detection of cancer

scientific article published on 01 February 2005

Regulation of oncogenic genes by MicroRNAs and pseudogenes in human lung cancer

scientific article

Relationships between pulmonary micro-RNA and proteome profiles, systemic cytogenetic damage and lung tumors in cigarette smoke-exposed mice treated with chemopreventive agents.

scientific article published on 24 May 2013

Release of MicroRNAs into Body Fluids from Ten Organs of Mice Exposed to Cigarette Smoke

scientific article published on 8 March 2018

Resistance to cancer chemotherapeutic drugs is determined by pivotal microRNA regulators

scientific article

Sensitivity of ocular anterior chamber tissues to oxidative damage and its relevance to the pathogenesis of glaucoma.

scientific article

Smoke-induced microRNA and related proteome alterations. Modulation by chemopreventive agents.

scientific article published on 26 September 2012

Survival of atherosclerotic patients as related to oxidative stress and gene polymorphisms

article

The Aicardi–Goutières syndrome. Molecular and clinical features of RNAse deficiency and microRNA overload

scientific article published on 15 April 2011

The Molecular Mechanisms of Adaptive Response Related to Environmental Stress

scientific article published on 25 September 2020

The Outflow Pathway: A Tissue With Morphological and Functional Unity.

scientific article

The Roles of miR-26, miR-29, and miR-203 in the Silencing of the Epigenetic Machinery during Melanocyte Transformation

scientific article published on 4 November 2015

The combined effect of age and socio-economic status on breast cancer survival

scientific article published on 15 March 2010

The dysfunction of the trabecular meshwork during glaucoma course

scientific article published on March 2015

The effects of environmental chemical carcinogens on the microRNA machinery.

scientific article published on 28 January 2014

The relationship between urban airborne pollution and short-term mortality: quantitative and qualitative aspects.

scientific article

The role and working conditions of Movement Science students employed in sport and recreational facilities: An Italian multicenter study

scientific article

Trabecular meshwork gene expression after selective laser trabeculoplasty

scientific article

Transgenerational inheritance of enhanced susceptibility to radiation-induced medulloblastoma in newborn Ptch1⁺/⁻ mice after paternal irradiation

scientific article published on 3 October 2015

Transplacental clastogenic and epigenetic effects of gold nanoparticles in mice.

scientific article published in September 2013

Upregulation of stem cell antigen-1 in the lung of neonatal mice exposed to environmental cigarette smoke

scientific article published on 01 September 2009

Volatile Organic Compounds in Anatomical Pathology Wards: Comparative and Qualitative Assessment of Indoor Airborne Pollution

scientific article published on 07 June 2017

[Molecular epidemiology in the identification of subjects susceptible to the effects of environmental carcinogens]

scientific article published on 01 November 1999

[Research on adducts of benzo(a)pyrene and DNA in different cells using synchronous fluorescence spectrophotometry]

scientific article published on 01 September 1991

[The toxicology and prevention of the risks of occupational exposure to aromatic polycyclic hydrocarbons. II. Toxicology. Exposure assessment. Environmental and biological monitoring]

scientific article published on 01 October 1997

miR-19 in blood plasma reflects lung cancer occurrence but is not specifically associated with radon exposure.

scientific article

miRNA Regulation of Glutathione Homeostasis in Cancer Initiation, Progression and Therapy Resistance

scientific article published on 17 December 2019

Paulina is supported by:

About Paulina

Help