Search filters

List of works by Markus Heimesaat

A guide to histomorphological evaluation of intestinal inflammation in mouse models.

scientific article published on 15 July 2014

Absence of Nucleotide-Oligomerization-Domain-2 Is Associated with Less Distinct Disease in Campylobacter jejuni Infected Secondary Abiotic IL-10 Deficient Mice

scientific article

Acute ileitis facilitates infection with multidrug resistant Pseudomonas aeruginosa in human microbiota-associated mice

scientific article published on 18 January 2017

Aggravation of different types of experimental colitis by depletion or adhesion blockade of neutrophils

scientific journal article

Amelioration of intestinal and systemic sequelae of murine Campylobacter jejuni infection by probiotic VSL#3 treatment

scientific article published on 11 April 2017

Anastomotic stability and wound healing of colorectal anastomoses sealed and sutured with a collagen fleece in a rat peritonitis model

scientific article

Anti-Inflammatory Properties of NAP in Acute Toxoplasma Gondii-Induced Ileitis in Mice

scientific article

Anti-inflammatory Effects of the Octapeptide NAP in Human Microbiota-Associated Mice Suffering from Subacute Ileitis.

scientific article published on 23 May 2018

Anti-inflammatory effects of resveratrol, curcumin and simvastatin in acute small intestinal inflammation

scientific article

Antibiotic treatment-induced secondary IgA deficiency enhances susceptibility to Pseudomonas aeruginosa pneumonia

scholarly article by Oliver H Robak et al published 1 August 2018 in Journal of Clinical Investigation

Antibiotic use during pregnancy increases offspring asthma severity in a dose-dependent manner

scientific article published on 16 February 2020

Antimicrobial and Immune-Modulatory Effects of Vitamin D Provide Promising Antibiotics-Independent Approaches to Tackle Bacterial Infections - Lessons Learnt from a Literature Survey

scientific article published on 13 August 2019

Arcobacter butzleri Induce Colonic, Extra-Intestinal and Systemic Inflammatory Responses in Gnotobiotic IL-10 Deficient Mice in a Strain-Dependent Manner

scientific article published on 25 September 2015

Atovaquone maintenance therapy prevents reactivation of toxoplasmic encephalitis in a murine model of reactivated toxoplasmosis

scientific article published on December 2004

CCR7 deficiency causes ectopic lymphoid neogenesis and disturbed mucosal tissue integrity

scientific article published on 3 October 2006

Campylobacter concisus Impairs Sodium Absorption in Colonic Epithelium via ENaC Dysfunction and Claudin-8 Disruption

scientific article published on 07 January 2020

Campylobacter jejuni induces acute enterocolitis in gnotobiotic IL-10-/- mice via Toll-like-receptor-2 and -4 signaling

scientific article (publication date: 2012)

Campylobacter jejuni infection of conventionally colonized mice lacking nucleotide-oligomerization-domain-2.

scientific article published on 21 January 2017

Campylobacteriosis of man : livestock as reservoir for Campylobacter species ⬇️

scientific article published on June 1, 2011

Carvacrol ameliorates acute campylobacteriosis in a clinical murine infection model

scientific article published on 08 January 2020

Changes of the Intestinal Microbiome-Host Homeostasis in HIV-Infected Individuals - A Focus on the Bacterial Gut Microbiome

scientific article published on 19 August 2017

Characterization of Arcobacter strains isolated from human stool samples: results from the prospective German prevalence study Arcopath

scientific article published on 08 January 2020

Chronic otitis media following infection by non-O1/non-O139 Vibrio cholerae: A case report and review of the literature

scientific article published on 13 August 2020

Colonic Expression of Genes Encoding Inflammatory Mediators and Gelatinases During Campylobacter Jejuni Infection of Conventional Infant Mice

scientific article published on 25 April 2016

Colonization resistance against genetically modified Escherichia coli K12 (W3110) strains is abrogated following broad-spectrum antibiotic treatment and acute ileitis

scientific article published on 23 September 2013

Commensal microbiota drive proliferation of conventional and Foxp3(+) regulatory CD4(+) T cells in mesenteric lymph nodes and Peyer's patches

scientific article published on 13 March 2013

Composition of intestinal microbiota in immune-deficient mice kept in three different housing conditions

scientific article

Compounds blocking methylglyoxal-induced protein modification and brain endothelial injury

scientific article

Comprehensive Kinetic Survey of Intestinal, Extra-Intestinal and Systemic Sequelae of Murine Ileitis Following Peroral Low-Dose Infection

scholarly article by Markus Heimesaat et al published 2019 in Frontiers in cellular and infection microbiology

Comprehensive Survey of Intestinal Microbiota Changes in Offspring of Human Microbiota-Associated Mice

scientific article published on 16 March 2017

Comprehensive postmortem analyses of intestinal microbiota changes and bacterial translocation in human flora associated mice

scientific article (publication date: 2012)

Correction: Novel Murine Infection Models Provide Deep Insights into the “Ménage à Trois” of Campylobacter jejuni, Microbiota and Host Innate Immunity

scientific article published on 23 August 2011

Curcumin Mitigates Immune-Induced Epithelial Barrier Dysfunction by Campylobacter jejuni

scientific article published on 28 September 2019

Depletion of Cultivatable Gut Microbiota by Broad-Spectrum Antibiotic Pretreatment Worsens Outcome After Murine Stroke

scientific article

Dissecting the Interplay Between Intestinal Microbiota and Host Immunity in Health and Disease: Lessons Learned from Germfree and Gnotobiotic Animal Models

scientific article

Editorial

Effects of glucagon-like peptide 1 on counterregulatory hormone responses, cognitive functions, and insulin secretion during hyperinsulinemic, stepped hypoglycemic clamp experiments in healthy volunteers

scientific article published in March 2002

Evaluation of the Xiamen AmonMed Biotechnology rapid diagnostic test COVID-19 IgM/IgG test kit (Colloidal gold)

scientific article published on 25 September 2020

Experience in practice. The use of modern media in pediatric anesthesia ⬇️

scientific article published on 05 September 2011

Fecal Microbiota Transplantation Decreases Intestinal Loads of Multi-Drug Resistant in Murine Carriers

scholarly article by Katharina Mrazek et al published 18 March 2019 in European journal of microbiology & immunology

Fecal Microbiota Transplantation, Commensal Escherichia coli and Lactobacillus johnsonii Strains Differentially Restore Intestinal and Systemic Adaptive Immune Cell Populations Following Broad-spectrum Antibiotic Treatment

scientific article published on 11 December 2017

Finding Novel Antibiotic Substances from Medicinal Plants - Antimicrobial Properties of Nigella Sativa Directed against Multidrug-resistant Bacteria

scientific article published on 16 March 2017

Function of Serine Protease HtrA in the Lifecycle of the Foodborne Pathogen

scientific article published in 2018

Glycyrrhizic Acid Decreases Gentamicin-Resistance in Vancomycin-Resistant Enterococci

scientific article published on 23 August 2016

Gram-negative bacteria aggravate murine small intestinal Th1-type immunopathology following oral infection with Toxoplasma gondii

scientific article published in December 2006

Gut Microbiota-Dependent Trimethylamine -Oxide Predicts Risk of Cardiovascular Events in Patients With Stroke and Is Related to Proinflammatory Monocytes

scientific article published on 01 September 2018

HIF prolyl hydroxylase-2 inhibition diminishes tumor growth through matrix metalloproteinase-induced TGFβ activation

scientific article

Helicobacter pylori induced gastric immunopathology is associated with distinct microbiota changes in the large intestines of long-term infected Mongolian gerbils

scientific article

Immune Responses to Broad-Spectrum Antibiotic Treatment and Fecal Microbiota Transplantation in Mice

scientific article

Immune responses upon Campylobacter jejuni infection of secondary abiotic mice lacking nucleotide-oligomerization-domain-2.

scientific article

Immune-modulatory Properties of the Octapeptide NAP in Campylobacter jejuni Infected Mice Suffering from Acute Enterocolitis

scientific article published on 26 May 2020

Immunology of Toxoplasma gondii

scientific article published on March 2011

Immunomodulatory Effects of the Neuropeptide Pituitary Adenylate Cyclase-Activating Polypeptide in Acute Toxoplasmosis.

scientific article published on 28 May 2019

Immunomodulatory and Antimicrobial Effects of Vitamin C

scientific article published on 16 August 2019

Immunopathological properties of the Campylobacter jejuni flagellins and the adhesin CadF as assessed in a clinical murine infection model

scientific article published on 17 May 2019

Impact of Campylobacter jejuni cj0268c knockout mutation on intestinal colonization, translocation, and induction of immunopathology in gnotobiotic IL-10 deficient mice

scientific article

Impact of metal ion homeostasis of genetically modified Escherichia coli Nissle 1917 and K12 (W3110) strains on colonization properties in the murine intestinal tract

scientific article published on 23 September 2013

Impact of the Gut Microbiota on Atorvastatin Mediated Effects on Blood Lipids

scientific article published on 25 May 2020

Inflammatory Immune Responses and Gut Microbiota Changes Following Campylobacter coli Infection of IL-10-/- Mice with Chronic Colitis

scientific article published on 11 July 2020

Inhibition of Helicobacter pylori urease activity in vivo by the synthetic nickel binding protein Hpn

scientific article published on 13 March 2013

Interleukin (IL)-23 mediates Toxoplasma gondii-induced immunopathology in the gut via matrixmetalloproteinase-2 and IL-22 but independent of IL-17.

scientific article

Interleukin-18 Mediates Immune Responses to Campylobacter jejuni Infection in Gnotobiotic Mice

scientific article (publication date: 2016)

Interleukin-22 induces interleukin-18 expression from epithelial cells during intestinal infection

scientific article published on 10 February 2015

Interleukin-7 links T lymphocyte and intestinal epithelial cell homeostasis

scientific article

Intestinal Expression of Genes Encoding Inflammatory Mediators and Gelatinases During Arcobacter Butzleri Infection of Gnotobiotic Il-10 Deficient Mice

scientific article published on 28 March 2016

Intestinal Microbiota Changes in Mice Lacking Pituitary Adenylate Cyclase Activating Polypeptide (PACAP) - Bifidobacteria Make the Difference

scientific article published on 11 September 2017

Intestinal and Systemic Immune Responses upon Multi-drug Resistant Pseudomonas aeruginosa Colonization of Mice Harboring a Human Gut Microbiota

scientific article published on 22 December 2017

Intestinal microbiota shifts towards elevated commensal Escherichia coli loads abrogate colonization resistance against Campylobacter jejuni in mice

scientific article (publication date: 2012)

Intestinal, extra-intestinal and systemic sequelae of Toxoplasma gondii induced acute ileitis in mice harboring a human gut microbiota

scientific article

Lactobacillus johnsonii ameliorates intestinal, extra-intestinal and systemic pro-inflammatory immune responses following murine Campylobacter jejuni infection

scientific article

Loss of Toll-like receptor 2 and 4 leads to differential induction of endoplasmic reticulum stress and proapoptotic responses in the intestinal epithelium under conditions of chronic inflammation

scientific article

Ly6C(hi) Monocytes Provide a Link between Antibiotic-Induced Changes in Gut Microbiota and Adult Hippocampal Neurogenesis

scientific article published on 19 May 2016

Ly6C(high) monocytes control cerebral toxoplasmosis.

scientific article published on 20 February 2015

Matrix Metalloproteinase-2 Mediates Intestinal Immunopathogenesis in Campylobacter Jejuni-Infected Infant Mice

scientific article

Microbiota Composition and Immune Responses During Campylobacter Jejuni Infection in Conventionally Colonized IL-10-/- Mice Lacking Nucleotide Oligomerization Domain 2.

scientific article published on 20 December 2016

Microbiota changes associated with ADNP deficiencies: rapid indicators for NAP (CP201) treatment of the ADNP syndrome and beyond

scientific article published on 18 February 2020

Microbiota composition and inflammatory immune responses upon peroral application of the commercial competitive exclusion product Aviguard® to microbiota-depleted wildtype mice

scientific article published on 27 July 2020

Modification of intestinal microbiota and its consequences for innate immune response in the pathogenesis of campylobacteriosis

scientific article

Multidrug-Resistant Accelerate Intestinal, Extra-Intestinal, and Systemic Inflammatory Responses in Human Microbiota-Associated Mice With Subacute Ileitis

article

Multidrug-Resistant Pseudomonas Aeruginosa Induce Systemic Pro-Inflammatory Immune Responses in Colonized Mice

scientific article published on 11 September 2017

Multidrug-resistant Pseudomonas aeruginosa aggravates inflammatory responses in murine chronic colitis

scientific article published on 27 April 2018

Murine Fecal Microbiota Transplantation Alleviates Intestinal and Systemic Immune Responses in Campylobacter jejuni Infected Mice Harboring a Human Gut Microbiota

scientific article published on 24 September 2019

Murine fecal microbiota transplantation lowers gastrointestinal pathogen loads and dampens pro-inflammatory immune responses in Campylobacter jejuni infected secondary abiotic mice

scientific article published on 24 December 2019

Murine infection models for the investigation of Campylobacter jejuni--host interactions and pathogenicity

scientific article published on March 2015

MyD88/TLR9 mediated immunopathology and gut microbiota dynamics in a novel murine model of intestinal graft-versus-host disease

scientific article published on August 2010

Myeloid differentiation factor-88 contributes to TLR9-mediated modulation of acute coxsackievirus B3-induced myocarditis in vivo

scientific article published on 12 March 2010

NK cell-derived IL-10 is critical for DC-NK cell dialogue at the maternal-fetal interface

scientific article

NOD2 (Nucleotide-Binding Oligomerization Domain 2) Is a Major Pathogenic Mediator of Coxsackievirus B3-Induced Myocarditis

scientific article published on September 2017

Novel Clinical Campylobacter jejuni Infection Models Based on Sensitization of Mice to Lipooligosaccharide, a Major Bacterial Factor Triggering Innate Immune Responses in Human Campylobacteriosis

scientific article published on 28 March 2020

Novel Murine Infection Models Provide Deep Insights into the “Ménage à Trois” of Campylobacter jejuni, Microbiota and Host Innate Immunity ⬇️

scientific article published on June 15, 2011

Nucleotide oligomerization domains 1 and 2: regulation of expression and function in preadipocytes

scientific article

Nucleotide-oligomerization-domain-2 affects commensal gut microbiota composition and intracerebral immunopathology in acute Toxoplasma gondii induced murine ileitis

scientific article (publication date: 2014)

Peptidase PepP is a novel virulence factor of Campylobacter jejuni contributing to murine campylobacteriosis

scientific article published on 25 June 2020

Peroral Low-Dose Toxoplasma gondii Infection of Human Microbiota-Associated Mice — A Subacute Ileitis Model to Unravel Pathogen–Host Interactions.

scientific article published on 16 April 2018

Pituitary Adenylate Cyclase-Activating Polypeptide Alleviates Intestinal, Extra-Intestinal and Systemic Inflammatory Responses during Acute Campylobacter jejuni-induced Enterocolitis in Mice

scientific article published on 30 September 2020

Pituitary Adenylate Cyclase-Activating Polypeptide-A Neuropeptide as Novel Treatment Option for Subacute Ileitis in Mice Harboring a Human Gut Microbiota

article published in 2019

Pituitary adenylate cyclase-activating polypeptide ameliorates experimental acute ileitis and extra-intestinal sequelae

scientific article

Preclinical Evaluation of Oral Urolithin-A for the Treatment of Acute Campylobacteriosis in <i>Campylobacter jejuni</i> Infected Microbiota-Depleted IL-10<sup>-/-</sup> Mice

scientific article published on 23 December 2020

Prevalence and antimicrobial susceptibility of Arcobacter species in human stool samples derived from out- and inpatients: the prospective German Arcobacter prevalence study Arcopath

scientific article published on 15 April 2020

Primary sterile necrotic cells fail to cross-prime CD8(+) T cells

scientific article

Profound defects in pancreatic beta-cell function in mice with combined heterozygous mutations in Pdx-1, Hnf-1alpha, and Hnf-3beta

scientific article

Propionate attenuates atherosclerosis by immune-dependent regulation of intestinal cholesterol metabolism

scientific article published on 01 February 2022

Protease Activity of HtrA Modulates Distinct Intestinal and Systemic Immune Responses in Infected Secondary Abiotic IL-10 Deficient Mice

article

RORγt+ Treg to Th17 ratios correlate with susceptibility to Giardia infection

scientific article published on 30 December 2019

Reduced degradation of the chemokine MCP-3 by matrix metalloproteinase-2 exacerbates myocardial inflammation in experimental viral cardiomyopathy

scientific article published on 10 October 2011

Regulation and migratory role of P-selectin ligands during intestinal inflammation

scientific article

Regulatory T Cell Specificity Directs Tolerance versus Allergy against Aeroantigens in Humans

scientific article

Resveratrol Alleviates Acute <i>Campylobacter jejuni</i> Induced Enterocolitis in a Preclinical Murine Intervention Study

scientific article published on 25 November 2020

Review of therapeutic options for infections with carbapenem-resistant Klebsiella pneumoniae

scientific article published on 17 September 2020

Role of Blimp-1 in programing Th effector cells into IL-10 producers

scientific article published on 29 July 2014

Role of goblet cell protein CLCA1 in murine DSS colitis

scientific article

SDS-coated atovaquone nanosuspensions show improved therapeutic efficacy against experimental acquired and reactivated toxoplasmosis by improving passage of gastrointestinal and blood-brain barriers

scientific article published in April 2010

Saponins increase susceptibility of vancomycin-resistant enterococci to antibiotic compounds

scientific article published on 16 December 2014

Shift towards pro-inflammatory intestinal bacteria aggravates acute murine colitis via Toll-like receptors 2 and 4.

scientific article

Small Intestinal Pro-Inflammatory Immune Responses Following Campylobacter Jejuni Infection of Secondary Abiotic IL-10-/- Mice Lacking Nucleotide-Oligomerization-Domain-2.

scientific article published on 27 June 2017

Small intestinal nematode infection of mice is associated with increased enterobacterial loads alongside the intestinal tract

scientific article

Survey of extra-intestinal immune responses in asymptomatic long-term Campylobacter jejuni-infected mice

scientific article published on 23 September 2013

Survey of small intestinal and systemic immune responses following murine Arcobacter butzleri infection

scientific article published on 19 October 2015

Synergistic Antimicrobial Effects of Cefabronchin®

scientific article published on 27 June 2019

TRIF is a critical survival factor in viral cardiomyopathy

scientific article published on 14 January 2011

The Campylobacter jejuni Cj0268c protein is required for adhesion and invasion in vitro

scientific journal article

The Goblet Cell Protein Clca1 (Alias mClca3 or Gob-5) Is Not Required for Intestinal Mucus Synthesis, Structure and Barrier Function in Naive or DSS-Challenged Mice

scientific article published on 10 July 2015

The Host-Specific Intestinal Microbiota Composition Impacts Campylobacter coli Infection in a Clinical Mouse Model of Campylobacteriosis

scientific article published on 29 September 2020

The IL-23/IL-22/IL-18 axis in murine Campylobacter jejuni infection

scientific article published on 06 July 2016

The Immunopathogenic Potential of Arcobacter butzleri - Lessons from a Meta-Analysis of Murine Infection Studies

scientific article

The NLRP3 Inflammasome Is Differentially Activated by Pneumolysin Variants and Contributes to Host Defense in Pneumococcal Pneumonia

scientific article published on 06 June 2011

The Probiotic Compound VSL#3 Modulates Mucosal, Peripheral, and Systemic Immunity Following Murine Broad-Spectrum Antibiotic Treatment

scientific article

The Role of Gelatinases in Campylobacter Jejuni Infection of Gnotobiotic Mice

scientific article

The Role of IL-23, IL-22, and IL-18 in Campylobacter Jejuni Infection of Conventional Infant Mice

scientific article published on 25 April 2016

The conundrum of colonization resistance against Campylobacter reloaded: The gut microbota composition in conventional mice does not prevent from Campylobacter coli infection

scientific article published on 01 May 2020

The impact of Toll-like-receptor-9 on intestinal microbiota composition and extra-intestinal sequelae in experimental Toxoplasma gondii induced ileitis

scientific article

The impact of serine protease HtrA in apoptosis, intestinal immune responses and extra-intestinal histopathology during Campylobacter jejuni infection of infant mice

scientific article

The induction of colitis and ileitis in mice is associated with marked increases in intestinal concentrations of stimulants of TLRs 2, 4, and 5

scientific article

The intestinal micro-environment imprints stromal cells to promote efficient Treg induction in gut-draining lymph nodes ⬇️

scientific article published on August 14, 2013

The microbiota regulates murine inflammatory responses to toxin-induced CNS demyelination but has minimal impact on remyelination

scientific article published on 18 November 2019

The octapetide NAP alleviates intestinal and extra-intestinal anti-inflammatory sequelae of acute experimental colitis

scientific article published on 27 December 2017

The role of serine protease HtrA in acute ulcerative enterocolitis and extra-intestinal immune responses during Campylobacter jejuni infection of gnotobiotic IL-10 deficient mice

scientific article

Toll-Like Receptor-4 Dependent Inflammatory Responses Following Intestinal Colonization of Secondary Abiotic IL10-Deficient Mice with Multidrug-Resistant Pseudomonas Aeruginosa

scientific article published on 11 September 2017

Toll-Like Receptor-4 Dependent Intestinal Gene Expression During Arcobacter Butzleri Infection of Gnotobiotic Il-10 Deficient Mice

scientific article published on 28 March 2016

Toll-Like Receptor-4 Dependent Intestinal and Systemic Sequelae Following Peroral Campylobacter coli Infection of IL10 Deficient Mice Harboring a Human Gut Microbiota

scientific article published on 18 May 2020

Toll-Like Receptor-4 Dependent Small Intestinal Immune Responses Following Murine Arcobacter Butzleri Infection

scientific article

Toll-Like Receptor-4 Is Involved in Mediating Intestinal and Extra-Intestinal Inflammation in <i>Campylobacter coli</i>-Infected Secondary Abiotic IL-10<sup>-/-</sup> Mice

scientific article published on 27 November 2020

Toll-Like Receptor-4 is Essential for Arcobacter Butzleri-Induced Colonic and Systemic Immune Responses in Gnotobiotic IL-10(-/-) Mice

scientific article

Toll-like receptor and IL-12 signaling control susceptibility to contact hypersensitivity

scientific article published on 25 August 2008

Toll-like receptor-4 deficiency attenuates doxorubicin-induced cardiomyopathy in mice

scientific article published on 5 March 2008

Toll-like receptor-4 differentially mediates intestinal and extra-intestinal immune responses upon multi-drug resistant Pseudomonas aeruginosa association of IL10-/- mice with chronic colitis

scientific article published on 7 November 2017

Toll-like receptor-4 modulates survival by induction of left ventricular remodeling after myocardial infarction in mice.

scientific article

Transition from an autoimmune-prone state to fatal autoimmune disease in CCR7 and RORγt double-deficient mice is dependent on gut microbiota

scientific article

Ventilator-induced lung injury is aggravated by antibiotic mediated microbiota depletion in mice

scientific article published on 29 October 2018

Vitamin C alleviates acute enterocolitis in Campylobacter jejuni infected mice

scientific article published on 19 February 2020

Vitamin D in Acute Campylobacteriosis-Results From an Intervention Study Applying a Clinical Campylobacter jejuni Induced Enterocolitis Model

scientific article published on 03 September 2019

Vitamin E as promising adjunct treatment option in the combat of infectious diseases caused by bacterial including multi-drug resistant pathogens - Results from a comprehensive literature survey

scientific article published on 05 November 2020

Paulina is supported by:

About Paulina

Help