List of works - Chary López-Pedrera

'Atherothrombosis-associated microRNAs in Antiphospholipid syndrome and Systemic Lupus Erythematosus patients'

scientific article published on 09 August 2016

AEE788 is a vascular endothelial growth factor receptor tyrosine kinase inhibitor with antiproliferative and proapoptotic effects in acute myeloid leukemia.

scientific article published on 7 April 2010

Additive effect of PTK787/ZK 222584, a potent inhibitor of VEGFR phosphorylation, with Idarubicin in the treatment of acute myeloid leukemia.

scientific article

Altered S-nitrosothiol homeostasis provides a survival advantage to breast cancer cells in HER2 tumors and reduces their sensitivity to trastuzumab.

scientific article published on 5 February 2016

Anticyclic citrullinated protein antibodies are implicated in the development of cardiovascular disease in rheumatoid arthritis.

scientific article

Antiphospholipid antibodies from patients with the antiphospholipid syndrome induce monocyte tissue factor expression through the simultaneous activation of NF-kappaB/Rel proteins via the p38 mitogen-activated protein kinase pathway, and of the MEK-

scientific article published on 01 January 2006

Antiphospholipid syndrome

scientific article published on 01 November 2003

Antiphospholipid syndrome and tissue factor: a thrombotic couple.

scientific article

Antithrombin III prevents early pulmonary dysfunction after lung transplantation in the dog.

scientific article published in December 2001

Atherosclerosis and cardiovascular disease in systemic lupus erythematosus: effects of in vivo statin treatment

scientific article published on 21 March 2014

C1-esterase inhibitor prevents early pulmonary dysfunction after lung transplantation in the dog

scientific article published on 01 March 1997

Cardiovascular risk in systemic autoimmune diseases: epigenetic mechanisms of immune regulatory functions

scientific article

Characterization of tissue factor expression on the human endothelial cell line ECV304 ⬇️

scientific article published on October 1, 1997

Circulating miRNAs as potential biomarkers of therapy effectiveness in rheumatoid arthritis patients treated with anti-TNFα

scientific article

CoCl2, a mimic of hypoxia, induces formation of polyploid giant cells with stem characteristics in colon cancer.

scientific article

Coordinated deregulation of cellular receptors, proangiogenic factors and intracellular pathways in acute myeloid leukaemia

scientific article published on 01 June 2007

Diagnostic potential of NETosis-derived products for disease activity, atherosclerosis and therapeutic effectiveness in Rheumatoid Arthritis patients.

scientific article published on 29 April 2017

Drug-induced lupus

scientific article published on 2 July 2009

ES936 stimulates DNA synthesis in HeLa cells independently on NAD(P)H:quinone oxidoreductase 1 inhibition, through a mechanism involving p38 MAPK.

scientific article published on 28 April 2010

Early restoration of immune and vascular phenotypes in systemic lupus erythematosus and rheumatoid arthritis patients after B cell depletion

scientific article published on 26 July 2019

Effects of Biological Therapies on Molecular Features of Rheumatoid Arthritis

scientific article published on 28 November 2020

Gene profiling reveals specific molecular pathways in the pathogenesis of atherosclerosis and cardiovascular disease in antiphospholipid syndrome, systemic lupus erythematosus and antiphospholipid syndrome with lupus

scientific article

Genomics and proteomics: a new approach for assessing thrombotic risk in autoimmune diseases.

scientific article published on October 2008

Global effects of fluvastatin on the prothrombotic status of patients with antiphospholipid syndrome.

scientific article published on 20 December 2010

HLA-B*08 identified as the most associated MHC locus for anti-carbamylated protein antibody-positive/anti-CCP-negative rheumatoid arthritis

scientific article published on 31 December 2020

Heterogeneity of growth hormone (GH)-producing cells in aging male rats: in vitro GH releasing activity of somatotrope subpopulations.

scientific article published on October 1996

Immunotherapy in antiphospholipid syndrome.

scientific article

Increased dihydroceramide/ceramide ratio mediated by defective expression of degs1 impairs adipocyte differentiation and function

scientific article published on 28 October 2014

Inhibition of Flt3-activating mutations does not prevent constitutive activation of ERK/Akt/STAT pathways in some AML cells: a possible cause for the limited effectiveness of monotherapy with small-molecule inhibitors

scientific article published on 01 March 2007

MEK inhibition induces caspases activation, differentiation blockade and PML/RARalpha degradation in acute promyelocytic leukaemia.

scientific article

Maintenance of S-nitrosothiol homeostasis plays an important role in growth suppression of estrogen receptor-positive breast tumors ⬇️

scientific article published on December 5, 2012

Mechanisms of atherosclerosis and cardiovascular disease in antiphospholipid syndrome and systemic lupus erythematosus. New therapeutic approaches.

scientific article

Mitochondrial dysfunction in antiphospholipid syndrome: implications in the pathogenesis of the disease and effects of coenzyme Q10 treatment

scientific article published on 23 April 2012

Monounsaturated fatty acid-enriched diet decreases plasma plasminogen activator inhibitor type 1

scientific article published on 01 January 1996

Nitric oxide and cancer: the emerging role of S-nitrosylation.

scientific article published on January 2012

Non-vitamin K antagonist oral anticoagulants and antiphospholipid syndrome

scientific article

Novel biomarkers of atherosclerosis and cardiovascular risk in autoimmune diseases: Genomics and proteomics approaches

scientific article published on February 2009

Oxidative stress in the pathogenesis of atherothrombosis associated with anti-phospholipid syndrome and systemic lupus erythematosus: new therapeutic approaches

scientific article

PXK locus in systemic lupus erythematosus: fine mapping and functional analysis reveals novel susceptibility gene ABHD6.

scientific article published on 17 February 2014

Potential use of statins in the treatment of antiphospholipid syndrome.

scientific article published on February 2012

Progression from high insulin resistance to type 2 diabetes does not entail additional visceral adipose tissue inflammation.

scientific article

Proteomic analysis in monocytes of antiphospholipid syndrome patients: deregulation of proteins related to the development of thrombosis

scientific article published on 01 September 2008

Proteomic approaches to evaluate protein S-nitrosylation in disease.

scientific article published on 15 June 2013

Proteomics insights into deregulated proteinS-nitrosylation and disease ⬇️

scientific article published on January 1, 2012

Regulation of TFPIα expression by miR-27a/b-3p in human endothelial cells under normal conditions and in response to androgens.

scientific article published on 27 February 2017

Simultaneous inhibition of EGFR/VEGFR and cyclooxygenase-2 targets stemness-related pathways in colorectal cancer cells

scientific article published on 24 June 2015

Splicing machinery is impaired in rheumatoid arthritis, associated with disease activity and modulated by anti-TNF therapy

scientific article published in 2021

The obese healthy paradox: is inflammation the answer?

scientific article published on 01 August 2010

Tocilizumab improves the proatherothrombotic profile of rheumatoid arthritis patients modulating endothelial dysfunction, NETosis, and inflammation.

scientific article

Ubiquinol Effects on Antiphospholipid Syndrome Prothrombotic Profile: A Randomized, Placebo-Controlled Trial

scientific article

Use of povidone-iodine during the first trimester of pregnancy: a correct practice?

scientific article published in February 2009

VEGF targeted therapy in acute myeloid leukemia ⬇️

scientific article published on October 29, 2010

Vascular endothelial growth factor expression in monocytes from patients with primary antiphospholipid syndrome

scientific article published on 12 September 2006

[Intracellular mechanisms involved in the angiogenic process in hematological malignancies]

scientific article published on 01 April 2008

List of works by Chary López-Pedrera

'Atherothrombosis-associated microRNAs in Antiphospholipid syndrome and Systemic Lupus Erythematosus patients'

AEE788 is a vascular endothelial growth factor receptor tyrosine kinase inhibitor with antiproliferative and proapoptotic effects in acute myeloid leukemia.

Additive effect of PTK787/ZK 222584, a potent inhibitor of VEGFR phosphorylation, with Idarubicin in the treatment of acute myeloid leukemia.

Altered S-nitrosothiol homeostasis provides a survival advantage to breast cancer cells in HER2 tumors and reduces their sensitivity to trastuzumab.

Anticyclic citrullinated protein antibodies are implicated in the development of cardiovascular disease in rheumatoid arthritis.

Antiphospholipid antibodies from patients with the antiphospholipid syndrome induce monocyte tissue factor expression through the simultaneous activation of NF-kappaB/Rel proteins via the p38 mitogen-activated protein kinase pathway, and of the MEK-

Antiphospholipid syndrome

Antiphospholipid syndrome and tissue factor: a thrombotic couple.

Antithrombin III prevents early pulmonary dysfunction after lung transplantation in the dog.

Atherosclerosis and cardiovascular disease in systemic lupus erythematosus: effects of in vivo statin treatment

C1-esterase inhibitor prevents early pulmonary dysfunction after lung transplantation in the dog

Cardiovascular risk in systemic autoimmune diseases: epigenetic mechanisms of immune regulatory functions

Characterization of tissue factor expression on the human endothelial cell line ECV304 ⬇️

Circulating miRNAs as potential biomarkers of therapy effectiveness in rheumatoid arthritis patients treated with anti-TNFα

CoCl2, a mimic of hypoxia, induces formation of polyploid giant cells with stem characteristics in colon cancer.

Coordinated deregulation of cellular receptors, proangiogenic factors and intracellular pathways in acute myeloid leukaemia

Diagnostic potential of NETosis-derived products for disease activity, atherosclerosis and therapeutic effectiveness in Rheumatoid Arthritis patients.

Drug-induced lupus

ES936 stimulates DNA synthesis in HeLa cells independently on NAD(P)H:quinone oxidoreductase 1 inhibition, through a mechanism involving p38 MAPK.

Early restoration of immune and vascular phenotypes in systemic lupus erythematosus and rheumatoid arthritis patients after B cell depletion

Effects of Biological Therapies on Molecular Features of Rheumatoid Arthritis

Gene profiling reveals specific molecular pathways in the pathogenesis of atherosclerosis and cardiovascular disease in antiphospholipid syndrome, systemic lupus erythematosus and antiphospholipid syndrome with lupus

Genomics and proteomics: a new approach for assessing thrombotic risk in autoimmune diseases.

Global effects of fluvastatin on the prothrombotic status of patients with antiphospholipid syndrome.

HLA-B*08 identified as the most associated MHC locus for anti-carbamylated protein antibody-positive/anti-CCP-negative rheumatoid arthritis

Heterogeneity of growth hormone (GH)-producing cells in aging male rats: in vitro GH releasing activity of somatotrope subpopulations.

Immunotherapy in antiphospholipid syndrome.

Increased dihydroceramide/ceramide ratio mediated by defective expression of degs1 impairs adipocyte differentiation and function

Inhibition of Flt3-activating mutations does not prevent constitutive activation of ERK/Akt/STAT pathways in some AML cells: a possible cause for the limited effectiveness of monotherapy with small-molecule inhibitors

MEK inhibition induces caspases activation, differentiation blockade and PML/RARalpha degradation in acute promyelocytic leukaemia.

Maintenance of S-nitrosothiol homeostasis plays an important role in growth suppression of estrogen receptor-positive breast tumors ⬇️

Mechanisms of atherosclerosis and cardiovascular disease in antiphospholipid syndrome and systemic lupus erythematosus. New therapeutic approaches.

Mitochondrial dysfunction in antiphospholipid syndrome: implications in the pathogenesis of the disease and effects of coenzyme Q10 treatment

Monounsaturated fatty acid-enriched diet decreases plasma plasminogen activator inhibitor type 1

Nitric oxide and cancer: the emerging role of S-nitrosylation.

Non-vitamin K antagonist oral anticoagulants and antiphospholipid syndrome

Novel biomarkers of atherosclerosis and cardiovascular risk in autoimmune diseases: Genomics and proteomics approaches

Oxidative stress in the pathogenesis of atherothrombosis associated with anti-phospholipid syndrome and systemic lupus erythematosus: new therapeutic approaches

PXK locus in systemic lupus erythematosus: fine mapping and functional analysis reveals novel susceptibility gene ABHD6.

Potential use of statins in the treatment of antiphospholipid syndrome.

Progression from high insulin resistance to type 2 diabetes does not entail additional visceral adipose tissue inflammation.

Proteomic analysis in monocytes of antiphospholipid syndrome patients: deregulation of proteins related to the development of thrombosis

Proteomic approaches to evaluate protein S-nitrosylation in disease.

Proteomics insights into deregulated proteinS-nitrosylation and disease ⬇️

Regulation of TFPIα expression by miR-27a/b-3p in human endothelial cells under normal conditions and in response to androgens.

Simultaneous inhibition of EGFR/VEGFR and cyclooxygenase-2 targets stemness-related pathways in colorectal cancer cells

Splicing machinery is impaired in rheumatoid arthritis, associated with disease activity and modulated by anti-TNF therapy

The obese healthy paradox: is inflammation the answer?

Tocilizumab improves the proatherothrombotic profile of rheumatoid arthritis patients modulating endothelial dysfunction, NETosis, and inflammation.

Ubiquinol Effects on Antiphospholipid Syndrome Prothrombotic Profile: A Randomized, Placebo-Controlled Trial

Use of povidone-iodine during the first trimester of pregnancy: a correct practice?

VEGF targeted therapy in acute myeloid leukemia ⬇️

Vascular endothelial growth factor expression in monocytes from patients with primary antiphospholipid syndrome

[Intracellular mechanisms involved in the angiogenic process in hematological malignancies]