List of works - Juha Tuukkanen

A metaphyseal defect model of the femur for studies of murine bone healing

scientific article

A novel component of epidermal cell-matrix and cell-cell contacts: transmembrane protein type XIII collagen

scientific article published on 01 October 1999

A novel treatment of grade III acromioclavicular joint dislocations with a C-hook implant.

scientific article published on 10 November 2005

Adenoviral VEGF-A gene transfer induces angiogenesis and promotes bone formation in healing osseous tissues

scientific article published in July 2003

Adhesion and mechanical properties of nanocrystalline hydroxyapatite coating obtained by conversion of atomic layer-deposited calcium carbonate on titanium substrate

scientific article published on 17 July 2018

Affecting osteoblastic responses with in vivo engineered potato pectin fragments.

scientific article

Age-related trends in vertebral dimensions

scientific article published on 24 April 2015

Alteration in the mechanical competence and structural properties in the femoral neck and vertebrae of ovariectomized rats

scientific article published on 01 April 1999

Autoimmune regulator is expressed in the cells regulating immune tolerance in thymus medulla.

scientific article published in April 1999

Behaviour of nitinol in osteoblast-like ROS-17 cell cultures.

scientific article

Biocompatibility and strength properties of nitinol shape memory alloy suture in rabbit tendon.

scientific article published in January 2004

Biocompatibility of sol-gel-derived titania-silica coated intramedullary NiTi nails.

scientific article published on 18 September 2008

Bone modeling and cell-material interface responses induced by nickel-titanium shape memory alloy after periosteal implantation.

scientific article published on July 1999

Bone modeling controlled by a nickel-titanium shape memory alloy intramedullary nail.

scientific article published in June 2002

Bone morphogenetic protein 3b expressing reindeer antler ⬇️

scientific article published on January 1, 2002

Bone morphogenetic proteins 4 and 2/7 induce osteogenic differentiation of mouse skin derived fibroblast and dermal papilla cells

scientific article published on 20 November 2013

Bone resorption by aryl hydrocarbon receptor-expressing osteoclasts is not disturbed by TCDD in short-term cultures.

scientific article published in August 2005

Bone-resorbing osteoclasts contain gap-junctional connexin-43.

scientific article

Carbonic anhydrase II plays a major role in osteoclast differentiation and bone resorption by effecting the steady state intracellular pH and Ca2+

scientific journal article

Changes in subchondral bone mineral density and collagen matrix organization in growing horses

scientific article published on 13 August 2008

Changes induced in growing rat bone by immobilization and remobilization

scientific article published on 01 January 1991

Clodronate prevents osteopenia and loss of trabecular connectivity in estrogen-deficient rats

scientific article published on 01 February 1998

Cloning of a novel bacteria-binding receptor structurally related to scavenger receptors and expressed in a subset of macrophages

scientific article

Comparison of radiographic and pQCT analyses of healing rat tibial fractures.

scientific article

Comparison of the bone modeling effects caused by curved and straight nickel-titanium intramedullary nails.

scientific article published in December 2002

Comparison of three-point bending test and peripheral quantitative computed tomography analysis in the evaluation of the strength of mouse femur and tibia

scientific article published on 01 August 1998

Compressive loading of the murine tibia reveals site-specific micro-scale differences in adaptation and maturation rates of bone

scientific article published on 05 December 2016

Connexin-mimetic peptide Gap 27 decreases osteoclastic activity

scientific article

Cross sectional properties of the human radial tuberosity ⬇️

scientific article published on October 24, 2011

Differentiation of osteoblasts on pectin-coated titanium.

scientific article published on 5 August 2008

Dioxin exposure in contaminated sawmill area: the use of molar teeth and bone of bank vole (Clethrionomys glareolus) and field vole (Microtus agrestis) as biomarkers

scientific article

Effect of bioactive extruded PLA/HA composite films on focal adhesion formation of preosteoblastic cells.

scientific article published on 19 June 2014

Effect of bioactive glass air-abrasion on the wettability and osteoblast proliferation on sandblasted and acid-etched titanium surfaces

scientific article published on 10 March 2020

Effect of exercise on osteoporosis induced by ovariectomy in rats

scientific article published on 01 January 1991

Effect of metal alloy surface stresses on the viability of ROS-17/2.8 osteoblastic cells.

scientific article published on September 2002

Effect of porosity on the osteointegration and bone ingrowth of a weight-bearing nickel-titanium bone graft substitute.

scientific article published in November 2003

Effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin exposure on bone material properties

scientific article published on 4 February 2010

Effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin on bone in two rat strains with different aryl hydrocarbon receptor structures.

scientific article

Effects of developmental exposure to perfluorooctanoic acid (PFOA) on long bone morphology and bone cell differentiation.

scientific article published on 08 April 2016

Effects of in utero and lactational TCDD exposure on bone development in differentially sensitive rat lines.

scientific article published on 2 March 2005

Endocrine, metabolic and apical effects of in utero and lactational exposure to non-dioxin-like 2,2′,3,4,4′,5,5′-heptachlorobiphenyl (PCB 180): A postnatal follow-up study in rats

scientific article published in 2021

Endostatin affects osteoblast behavior in vitro, but collagen XVIII/endostatin is not essential for skeletal development in vivo

scientific article published on 10 September 2009

Endostatin inhibits VEGF-A induced osteoclastic bone resorption in vitro

scientific article published on 13 July 2006

Endostatin inhibits endochondral ossification

scholarly article by A Sipola published in January 2007

Enzalutamide Reduces the Bone Mass in the Axial But Not the Appendicular Skeleton in Male Mice

scientific article published on 20 November 2015

Estrogen deposits extra mineral into bones of female rats in puberty, but simultaneously seems to suppress the responsiveness of female skeleton to mechanical loading

scientific article

Estrogen receptor-α expression in neuronal cells affects bone mass

scientific article published on 3 January 2012

Estrogen receptor-α in osteocytes is important for trabecular bone formation in male mice

scientific article published on 23 January 2013

Exercise can provide protection against bone loss and prevent the decrease in mechanical strength of femoral neck in ovariectomized rats

scientific article published on 01 October 1994

Expression of the Hutchinson-Gilford progeria mutation during osteoblast development results in loss of osteocytes, irregular mineralization, and poor biomechanical properties

scientific article

Female Mice Lacking Estrogen Receptor-α in Hypothalamic Proopiomelanocortin (POMC) Neurons Display Enhanced Estrogenic Response on Cortical Bone Mass

scientific article published on 02 June 2016

Femoral neck is a sensitive indicator of bone loss in immobilized hind limb of mouse.

scientific article

Femoral neck response to exercise and subsequent deconditioning in young and adult rats

scientific article published on 01 July 2003

Femoral neck strength of mouse in two loading configurations: method evaluation and fracture characteristics

scientific article

Fibronectin modulates osteoblast behavior on Nitinol

scientific article published on 01 March 2009

Gap junctional communication is involved in differentiation of osteoclasts from bone marrow and peripheral blood monocytes.

scientific article published on 7 May 2018

High dietary phosphate intake reduces bone strength in the growing rat skeleton.

scientific article published in January 2007

Hydroxyapatite as a nanomaterial for advanced tissue engineering and drug therapy.

scientific article

Immunolocalization of EMMPRIN (CD147) in the human eye and detection of soluble form of EMMPRIN in ocular fluids.

scientific article published on November 2006

In utero and lactational exposure to Aroclor 1254 affects bone geometry, mineral density and biomechanical properties of rat offspring.

scientific article published on 11 August 2011

In utero/lactational 2,3,7,8-tetrachlorodibenzo-p-dioxin exposure impairs molar tooth development in rats.

scientific article

In vivo biocompatibility evaluation of nickel-titanium shape memory metal alloy: muscle and perineural tissue responses and encapsule membrane thickness

scientific article published on 01 September 1998

Increased amount of phosphorylated proinflammatory osteopontin in rheumatoid arthritis synovia is associated to decreased tartrate-resistant acid phosphatase 5B/5A ratio.

scientific article published on 08 August 2017

Inducible Wnt16 inactivation: WNT16 regulates cortical bone thickness in adult mice

scientific article published on 12 March 2018

Influence of intensity and changes of physical activity on bone mineral density of immature equine subchondral bone.

scientific article published on July 2009

Influence of physical activity on vertebral size

scientific article published on 24 April 2010

Influence of physical activity on vertebral strength during late adolescence

scientific article published on 16 January 2013

Keratinocytes cultured from patients with Hailey-Hailey disease and Darier disease display distinct patterns of calcium regulation.

scientific article published in July 2005

Liver-derived IGF-I regulates cortical bone mass but is dispensable for the osteogenic response to mechanical loading in female mice

scientific article published on 24 May 2016

Long-term administration of clodronate does not prevent fracture healing in rats.

scientific article

Long-term effects of ovariectomy on the mechanical properties and chemical composition of rat bone

scientific article published on 01 March 1997

Long-term voluntary exercise of male mice induces more beneficial effects on cancellous and cortical bone than on the collagenous matrix

scientific article published on 23 August 2009

Maternal beef and postweaning herring diets increase bone mineral density and strength in mouse offspring

scientific article

Mechanical properties in long bones of rat osteopetrotic mutations

scientific article published on 01 February 2002

Melt spinning of poly(lactic acid) and hydroxyapatite composite fibers: influence of the filler content on the fiber properties

scientific article published on 12 July 2013

Microstructural properties of bone in rat vertebra after long-term clodronate treatment

scientific article

Mineral density and bone strength are dissociated in long bones of rat osteopetrotic mutations

scientific article published on 01 October 2000

Multiple miliary osteoma cutis is a distinct disease entity: four case reports and review of the literature ⬇️

scientific article published on February 17, 2011

New insights to the role of aryl hydrocarbon receptor in bone phenotype and in dioxin-induced modulation of bone microarchitecture and material properties.

scientific article published on 13 September 2013

Omeprazole, a specific inhibitor of H+-K+-ATPase, inhibits bone resorption in vitro

scientific article published on 01 February 1986

Organization of osteoclast microfilaments during the attachment to bone surface in vitro.

scientific article

Osteoblast-derived WNT16 represses osteoclastogenesis and prevents cortical bone fragility fractures

scientific article

Osteoclastogenesis is influenced by modulation of gap junctional communication with antiarrhythmic peptides.

scientific article published on 16 December 2012

Osteoclasts in the interface with electrospun hydroxyapatite

scientific article published on 28 August 2015

Osteogenic Differentiation of Human Mesenchymal Stem cells in a 3D Woven Scaffold

scientific article published on 11 July 2018

Ovariectomy-induced bone loss can be affected by different intensities of treadmill running exercise in rats

scientific article published on 01 May 1997

Perfluoroalkyl substances in human bone: concentrations in bones and effects on bone cell differentiation

scientific article published on 28 July 2017

Perinatal Exposure to Environmental Contaminants Detected in Canadian Arctic Human Populations Changes Bone Geometry and Biomechanical Properties in Rat Offspring ⬇️

scientific article published on January 1, 2011

Peripheral blood monocytes show increased osteoclast differentiation potential compared to bone marrow monocytes

scientific article published on 12 September 2018

Physical Exercise Improves Properties of Bone and Its Collagen Network in Growing and Maturing Mice

scientific article published on 30 July 2009

Polarity of mature human odontoblasts.

scientific article published on 16 September 2013

Porcupine inhibitors impair trabecular and cortical bone mass and strength in mice.

scientific article published on 2 May 2018

Prednisolone treatment reduces the osteogenic effects of loading in mice.

scientific article published on 7 April 2018

Preliminary Report: Osteoarthritis and Rheumatoid Arthritis Synovial Fluid Increased Osteoclastogenesis <i>In Vitro</i> by Monocyte Differentiation Pathway Regulating Cytokines

scientific article published on 31 May 2022

Preparation and bioactive properties of nanocrystalline hydroxyapatite thin films obtained by conversion of atomic layer deposited calcium carbonate

scientific article published in September 2014

Progression of human aortic valve stenosis is associated with tenascin-C expression

scientific article published on 01 January 2002

Quantitative characterization of changes in bone geometry, mineral density and biomechanical properties in two rat strains with different Ah-receptor structures after long-term exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin

scientific journal article

Raccoon dog model shows preservation of bone during prolonged catabolism and reduced physical activity.

scientific article

Renal insufficiency-induced bone loss is associated with an increase in bone size and preservation of strength in rat proximal femur.

scientific article published on 3 April 2006

SERMs have substance-specific effects on bone, and these effects are mediated via ERαAF-1 in female mice

scientific article published on 05 April 2016

Severe Extracellular Matrix Abnormalities and Chondrodysplasia in Mice Lacking Collagen Prolyl 4-Hydroxylase Isoenzyme II in Combination with a Reduced Amount of Isoenzyme I.

scientific article published on 22 May 2015

Significance of the extracellular domain and the carbohydrates of the human neutrophil N-formyl peptide chemotactic receptor for the signal transduction by the receptor.

scientific article

Synergistic effects of tributyltin and 2,3,7,8-tetrachlorodibenzo-p-dioxin on differentiating osteoblasts and osteoclasts.

scientific article

TGF-beta1 secretion of ROS-17/2.8 cultures on NiTi implant material.

scientific article published on August 2002

Temporal trends in vertebral size and shape from medieval to modern-day

scientific article

The Bone Sparing Effects of 2-Methoxyestradiol Are Mediated via Estrogen Receptor-α in Male Mice

scientific article published on 15 September 2016

The association between knee breadth and body mass: The Northern Finland Birth Cohort 1966 case study

scientific article published on 07 August 2019

The bone-sparing effects of estrogen and WNT16 are independent of each other

scientific article

The effect of oxide thickness on osteoblast attachment and survival on NiTi alloy.

scientific article published on 13 January 2007

The effect of perinatal TCDD exposure on caries susceptibility in rats.

scientific article published on 16 March 2006

The effect of training on the recovery from immobilization-induced bone loss in rats

scientific article published on August 1, 1992

The mechanical strength of bone in different rat models of experimental osteoporosis

scientific article published on 01 September 1994

The role of activation functions 1 and 2 of estrogen receptor-α for the effects of estradiol and selective estrogen receptor modulators in male mice

scientific article published on May 2013

The role of membrane ERα signaling in bone and other major estrogen responsive tissues

scientific article published on 08 July 2016

Toxicological profile of ultrapure 2,2',3,4,4',5,5'-heptachlorbiphenyl (PCB 180) in adult rats

scientific article

Transgene silencing of the Hutchinson-Gilford progeria syndrome mutation results in a reversible bone phenotype, whereas resveratrol treatment does not show overall beneficial effects

scientific article

Type XIII Collagen Strongly Affects Bone Formation in Transgenic Mice

Wnt-4 signaling is involved in the control of smooth muscle cell fate via Bmp-4 in the medullary stroma of the developing kidney

scientific article

List of works by Juha Tuukkanen

A metaphyseal defect model of the femur for studies of murine bone healing

A novel component of epidermal cell-matrix and cell-cell contacts: transmembrane protein type XIII collagen

A novel treatment of grade III acromioclavicular joint dislocations with a C-hook implant.

Adenoviral VEGF-A gene transfer induces angiogenesis and promotes bone formation in healing osseous tissues

Adhesion and mechanical properties of nanocrystalline hydroxyapatite coating obtained by conversion of atomic layer-deposited calcium carbonate on titanium substrate

Affecting osteoblastic responses with in vivo engineered potato pectin fragments.

Age-related trends in vertebral dimensions

Alteration in the mechanical competence and structural properties in the femoral neck and vertebrae of ovariectomized rats

Autoimmune regulator is expressed in the cells regulating immune tolerance in thymus medulla.

Behaviour of nitinol in osteoblast-like ROS-17 cell cultures.

Biocompatibility and strength properties of nitinol shape memory alloy suture in rabbit tendon.

Biocompatibility of sol-gel-derived titania-silica coated intramedullary NiTi nails.

Bone modeling and cell-material interface responses induced by nickel-titanium shape memory alloy after periosteal implantation.

Bone modeling controlled by a nickel-titanium shape memory alloy intramedullary nail.

Bone morphogenetic protein 3b expressing reindeer antler ⬇️

Bone morphogenetic proteins 4 and 2/7 induce osteogenic differentiation of mouse skin derived fibroblast and dermal papilla cells

Bone resorption by aryl hydrocarbon receptor-expressing osteoclasts is not disturbed by TCDD in short-term cultures.

Bone-resorbing osteoclasts contain gap-junctional connexin-43.

Carbonic anhydrase II plays a major role in osteoclast differentiation and bone resorption by effecting the steady state intracellular pH and Ca2+

Changes in subchondral bone mineral density and collagen matrix organization in growing horses

Changes induced in growing rat bone by immobilization and remobilization

Clodronate prevents osteopenia and loss of trabecular connectivity in estrogen-deficient rats

Cloning of a novel bacteria-binding receptor structurally related to scavenger receptors and expressed in a subset of macrophages

Comparison of radiographic and pQCT analyses of healing rat tibial fractures.

Comparison of the bone modeling effects caused by curved and straight nickel-titanium intramedullary nails.

Comparison of three-point bending test and peripheral quantitative computed tomography analysis in the evaluation of the strength of mouse femur and tibia

Compressive loading of the murine tibia reveals site-specific micro-scale differences in adaptation and maturation rates of bone

Connexin-mimetic peptide Gap 27 decreases osteoclastic activity

Cross sectional properties of the human radial tuberosity ⬇️

Differentiation of osteoblasts on pectin-coated titanium.

Dioxin exposure in contaminated sawmill area: the use of molar teeth and bone of bank vole (Clethrionomys glareolus) and field vole (Microtus agrestis) as biomarkers

Effect of bioactive extruded PLA/HA composite films on focal adhesion formation of preosteoblastic cells.

Effect of bioactive glass air-abrasion on the wettability and osteoblast proliferation on sandblasted and acid-etched titanium surfaces

Effect of exercise on osteoporosis induced by ovariectomy in rats

Effect of metal alloy surface stresses on the viability of ROS-17/2.8 osteoblastic cells.

Effect of porosity on the osteointegration and bone ingrowth of a weight-bearing nickel-titanium bone graft substitute.

Effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin exposure on bone material properties

Effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin on bone in two rat strains with different aryl hydrocarbon receptor structures.

Effects of developmental exposure to perfluorooctanoic acid (PFOA) on long bone morphology and bone cell differentiation.

Effects of in utero and lactational TCDD exposure on bone development in differentially sensitive rat lines.

Endocrine, metabolic and apical effects of in utero and lactational exposure to non-dioxin-like 2,2′,3,4,4′,5,5′-heptachlorobiphenyl (PCB 180): A postnatal follow-up study in rats

Endostatin affects osteoblast behavior in vitro, but collagen XVIII/endostatin is not essential for skeletal development in vivo

Endostatin inhibits VEGF-A induced osteoclastic bone resorption in vitro

Endostatin inhibits endochondral ossification

Enzalutamide Reduces the Bone Mass in the Axial But Not the Appendicular Skeleton in Male Mice

Estrogen deposits extra mineral into bones of female rats in puberty, but simultaneously seems to suppress the responsiveness of female skeleton to mechanical loading

Estrogen receptor-α expression in neuronal cells affects bone mass

Estrogen receptor-α in osteocytes is important for trabecular bone formation in male mice

Exercise can provide protection against bone loss and prevent the decrease in mechanical strength of femoral neck in ovariectomized rats

Expression of the Hutchinson-Gilford progeria mutation during osteoblast development results in loss of osteocytes, irregular mineralization, and poor biomechanical properties

Female Mice Lacking Estrogen Receptor-α in Hypothalamic Proopiomelanocortin (POMC) Neurons Display Enhanced Estrogenic Response on Cortical Bone Mass

Femoral neck is a sensitive indicator of bone loss in immobilized hind limb of mouse.

Femoral neck response to exercise and subsequent deconditioning in young and adult rats

Femoral neck strength of mouse in two loading configurations: method evaluation and fracture characteristics

Fibronectin modulates osteoblast behavior on Nitinol

Gap junctional communication is involved in differentiation of osteoclasts from bone marrow and peripheral blood monocytes.

High dietary phosphate intake reduces bone strength in the growing rat skeleton.

Hydroxyapatite as a nanomaterial for advanced tissue engineering and drug therapy.

Immunolocalization of EMMPRIN (CD147) in the human eye and detection of soluble form of EMMPRIN in ocular fluids.

In utero and lactational exposure to Aroclor 1254 affects bone geometry, mineral density and biomechanical properties of rat offspring.

In utero/lactational 2,3,7,8-tetrachlorodibenzo-p-dioxin exposure impairs molar tooth development in rats.

In vivo biocompatibility evaluation of nickel-titanium shape memory metal alloy: muscle and perineural tissue responses and encapsule membrane thickness

Increased amount of phosphorylated proinflammatory osteopontin in rheumatoid arthritis synovia is associated to decreased tartrate-resistant acid phosphatase 5B/5A ratio.

Inducible Wnt16 inactivation: WNT16 regulates cortical bone thickness in adult mice

Influence of intensity and changes of physical activity on bone mineral density of immature equine subchondral bone.

Influence of physical activity on vertebral size

Influence of physical activity on vertebral strength during late adolescence

Keratinocytes cultured from patients with Hailey-Hailey disease and Darier disease display distinct patterns of calcium regulation.

Liver-derived IGF-I regulates cortical bone mass but is dispensable for the osteogenic response to mechanical loading in female mice

Long-term administration of clodronate does not prevent fracture healing in rats.

Long-term effects of ovariectomy on the mechanical properties and chemical composition of rat bone

Long-term voluntary exercise of male mice induces more beneficial effects on cancellous and cortical bone than on the collagenous matrix

Maternal beef and postweaning herring diets increase bone mineral density and strength in mouse offspring

Mechanical properties in long bones of rat osteopetrotic mutations

Melt spinning of poly(lactic acid) and hydroxyapatite composite fibers: influence of the filler content on the fiber properties

Microstructural properties of bone in rat vertebra after long-term clodronate treatment

Mineral density and bone strength are dissociated in long bones of rat osteopetrotic mutations

Multiple miliary osteoma cutis is a distinct disease entity: four case reports and review of the literature ⬇️

New insights to the role of aryl hydrocarbon receptor in bone phenotype and in dioxin-induced modulation of bone microarchitecture and material properties.