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List of works by Simone de Jong

A gene co-expression network in whole blood of schizophrenia patients is independent of antipsychotic-use and enriched for brain-expressed genes

scientific article

Accurate and fast multiple-testing correction in eQTL studies

scientific article published on 28 May 2015

An integrative multi-scale analysis of the dynamic DNA methylation landscape in aging

scientific article published on 18 February 2015

Applying polygenic risk scoring for psychiatric disorders to a large family with bipolar disorder and major depressive disorder

scientific article published on 08 October 2018

Associations between polygenic risk scores for four psychiatric illnesses and brain structure using multivariate pattern recognition

scientific article published on 09 October 2018

Characterization of genome-methylome interactions in 22 nuclear pedigrees

scientific article

Common inversion polymorphism at 17q21.31 affects expression of multiple genes in tissue-specific manner ⬇️

scientific article published on September 6, 2012

Common variant at 16p11.2 conferring risk of psychosis.

scientific article

Common variants at VRK2 and TCF4 conferring risk of schizophrenia

scientific article published on 26 July 2011

Development of multivariable models to predict change in Body Mass Index within a clinical trial population of psychotic individuals

scientific article published on 7 November 2017

Expression QTL analysis of top loci from GWAS meta-analysis highlights additional schizophrenia candidate genes

scientific article

Gene expression over the course of schizophrenia: from clinical high-risk for psychosis to chronic stages

article

Gene expression profiling in C57BL/6J and A/J mouse inbred strains reveals gene networks specific for brain regions independent of genetic background

scientific article

Gene networks associated with conditional fear in mice identified using a systems genetics approach

scientific article

Gene-expression analysis of clozapine treatment in whole blood of patients with psychosis

scientific article published on 16 June 2016

Gene-set analysis based on the pharmacological profiles of drugs to identify repurposing opportunities in schizophrenia.

scientific article published on 14 June 2016

Genetic analysis of DNA methylation and gene expression levels in whole blood of healthy human subjects

scientific article

Genome-wide Burden of Rare Short Deletions Is Enriched in Major Depressive Disorder in Four Cohorts

scientific article published on 13 March 2019

Genome-wide association analyses identify new risk variants and the genetic architecture of amyotrophic lateral sclerosis

scientific article published on 25 July 2016

Genome-wide association study identifies 30 loci associated with bipolar disorder.

scientific article

Genome-wide association study of monoamine metabolite levels in human cerebrospinal fluid.

scientific article

Genome-wide expression and response to exposure-based psychological therapy for anxiety disorders.

scientific article published on 29 August 2017

Hippocampal gene expression analysis highlights Ly6a/Sca-1 as candidate gene for previously mapped novelty induced behaviors in mice

scientific article

Identification of schizophrenia-associated loci by combining DNA methylation and gene expression data from whole blood

scientific article

Identifying predictors of activity based anorexia susceptibility in diverse genetic rodent populations

scientific article

Immune signatures and disorder-specific patterns in a cross-disorder gene expression analysis

scientific article published on 05 May 2016

Liprin alfa 2 gene expression is increased by cannabis use and associated with neuropsychological function

scientific article published on 15 March 2019

Peripheral blood gene expression profiles linked to monoamine metabolite levels in cerebrospinal fluid.

scientific article published on 13 December 2016

Seasonal changes in gene expression represent cell-type composition in whole blood

scientific article published on 07 January 2014

Separate and combined effects of genetic variants and pre-treatment whole blood gene expression on response to exposure-based cognitive behavioural therapy for anxiety disorders

scientific article published on 4 July 2016

Stimulated gene expression profiles as a blood marker of major depressive disorder.

scientific article published on 14 May 2010

Stratified gene expression analysis identifies major amyotrophic lateral sclerosis genes

scientific article published on 19 February 2015

TCF4 (e2-2; ITF2): a schizophrenia-associated gene with pleiotropic effects on human disease

scientific article

Telomere length as a predictor of emotional processing in the brain

scientific article published on 04 December 2018

The Alkaline Phosphatase (ALPL) Locus Is Associated with B6 Vitamer Levels in CSF and Plasma

article

The genome-wide expression effects of escitalopram and its relationship to neurogenesis, hippocampal volume, and antidepressant response

scientific article

The polygenic nature of telomere length and the anti-ageing properties of lithium.

scientific article published on 18 December 2018

The polygenic risk for bipolar disorder influences brain regional function relating to visual and default state processing of emotional information

scientific article

Transcriptome-wide mega-analyses reveal joint dysregulation of immunologic genes and transcription regulators in brain and blood in schizophrenia

scientific article published on 19 July 2016

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