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List of works by John T Poirier

A rapid bead-based radioligand binding assay for the determination of target-binding fraction and quality control of radiopharmaceuticals

scientific article published on 01 April 2019

Acquired BRAF Rearrangements Induce Secondary Resistance to EGFR therapy in EGFR-Mutated Lung Cancers

scientific article published on 01 March 2019

Anthrax toxin receptor 1 is the cellular receptor for Seneca Valley virus.

scientific article published on 26 June 2017

Author Correction: Molecular subtypes of small cell lung cancer: a synthesis of human and mouse model data

scientific article published on 01 July 2019

CD47-blocking immunotherapies stimulate macrophage-mediated destruction of small-cell lung cancer

scientific article published on 13 June 2016

CRISPR Libraries and Screening.

scientific article published on 6 November 2017

Characterization of a full-length infectious cDNA clone and a GFP reporter derivative of the oncolytic picornavirus SVV-001 ⬇️

scientific article published on September 12, 2012

Chemosensitive Relapse in Small Cell Lung Cancer Proceeds through an EZH2-SLFN11 Axis.

scientific article published on February 2017

Circulating Tumor DNA Profiling in Small-Cell Lung Cancer Identifies Potentially Targetable Alterations

scientific article published on 12 July 2019

Combined Inhibition of NEDD8-Activating Enzyme and mTOR Suppresses NF2 Loss-Driven Tumorigenesis.

scientific article published on 3 May 2017

Correction: Seneca Valley Virus 3Cpro Substrate Optimization Yields Efficient Substrates for use in Peptide-Prodrug Therapy.

scientific article published on 19 August 2015

DNA methylation in small cell lung cancer defines distinct disease subtypes and correlates with high expression of EZH2.

scientific article

Design, execution, and analysis of pooled in vitro CRISPR/Cas9 screens

scientific article

Emergence of a High-Plasticity Cell State during Lung Cancer Evolution

scientific article published on 08 July 2020

Epigenetic CRISPR screens identify Npm1 as a therapeutic vulnerability in non-small cell lung cancer

scientific article published on 09 July 2020

Evaluation of azacitidine and entinostat as sensitization agents to cytotoxic chemotherapy in preclinical models of non-small cell lung cancer

scientific article

Fc-mediated Anomalous Biodistribution of Therapeutic Antibodies in Immunodeficient Mouse Models.

scientific article published on 23 January 2018

Functional interrogation of a SARS-CoV-2 host protein interactome identifies unique and shared coronavirus host factors

scientific article published on 11 September 2020

Genome-scale identification of SARS-CoV-2 and pan-coronavirus host factor networks

scientific article published on 08 October 2020

Genomic and transcriptomic analysis of a library of small cell lung cancer patient-derived xenografts

scientific article published on 19 April 2022

HER2-Mediated Internalization of Cytotoxic Agents in ERBB2 Amplified or Mutant Lung Cancers

scientific article published on 25 March 2020

Histone Code Aberrancies in Small Cell Lung Cancer.

scientific article published in April 2017

Integrative Genomic Characterization Identifies Molecular Subtypes of Lung Carcinoids

scientific article published on 12 July 2019

Keap1 loss promotes Kras-driven lung cancer and results in dependence on glutaminolysis.

scientific article published on 2 October 2017

Lineage reversion drives WNT independence in intestinal cancer

scientific article published on 16 June 2020

MYC paralog-dependent apoptotic priming orchestrates a spectrum of vulnerabilities in small cell lung cancer

scientific article published on 02 August 2019

MYC, MAX, and small cell lung cancer.

scientific article

Molecular subtypes of small cell lung cancer: a synthesis of human and mouse model data

scientific article published on 01 May 2019

NK cell-mediated cytotoxicity contributes to tumor control by a cytostatic drug combination

scientific article published on 01 December 2018

New Approaches to SCLC Therapy: From the Laboratory to the Clinic

scientific article published on 01 February 2020

Next-Generation Sequencing of Pulmonary Large Cell Neuroendocrine Carcinoma Reveals Small Cell Carcinoma-like and Non-Small Cell Carcinoma-like Subsets.

scientific article published on 9 March 2016

Noninvasive Interrogation of DLL3 Expression in Metastatic Small Cell Lung Cancer

scientific article published on 9 May 2017

ONECUT2 is a driver of neuroendocrine prostate cancer

scientific article published in Nature Communications

P-selectin is a nanotherapeutic delivery target in the tumor microenvironment.

scientific article published on June 2016

PARP Inhibitor Activity Correlates with SLFN11 Expression and Demonstrates Synergy with Temozolomide in Small Cell Lung Cancer.

scientific article published on 20 July 2016

Peptide-based PET quantifies target engagement of PD-L1 therapeutics

scientific article published on 07 January 2019

Phase I Clinical Study of Seneca Valley Virus (SVV-001),a Replication-Competent Picornavirus, in Advanced Solid Tumors with Neuroendocrine Features ⬇️

scientific article published on February 8, 2011

Phase I trial of Seneca Valley Virus (NTX-010) in children with relapsed/refractory solid tumors: a report of the Children's Oncology Group

scientific article

Positron-Emission Tomographic Imaging of a Fluorine 18-Radiolabeled Poly(ADP-Ribose) Polymerase 1 Inhibitor Monitors the Therapeutic Efficacy of Talazoparib in SCLC Patient-Derived Xenografts

scientific article published on 11 June 2019

ProteomeGenerator: A framework for comprehensive proteomics based on de novo transcriptome assembly and high-accuracy peptide mass spectral matching

scientific article published on 19 October 2018

Quantitation of Murine Stroma and Selective Purification of the Human Tumor Component of Patient-Derived Xenografts for Genomic Analysis

scientific article

RB loss in resistant EGFR mutant lung adenocarcinomas that transform to small-cell lung cancer

scientific article

RET mutations in neuroendocrine tumors: including small-cell lung cancer

scientific article published on September 2014

Rapamycin rescues ABT-737 efficacy in small cell lung cancer

scientific article published on 10 March 2014

Regenerative lineages and immune-mediated pruning in lung cancer metastasis

scientific article published on 10 February 2020

Rlf-Mycl Gene Fusion Drives Tumorigenesis and Metastasis in a Mouse Model of Small Cell Lung Cancer

scientific article published on 01 December 2021

Selective tropism of Seneca Valley virus for variant subtype small cell lung cancer.

scientific article published on 05 June 2013

Seneca Valley Virus 3Cpro Substrate Optimization Yields Efficient Substrates for Use in Peptide-Prodrug Therapy

scientific article published on 12 June 2015

Small-cell lung cancer in 2016: Shining light on novel targets and therapies.

scientific article published on 13 December 2016

TMEM41B is a pan-flavivirus host factor

scientific article published on 11 October 2020

Talazoparib Is a Potent Radiosensitizer in Small Cell Lung Cancer Cell Lines and Xenografts

scientific article published on 26 June 2018

Target engagement imaging of PARP inhibitors in small-cell lung cancer.

scientific article published on 12 January 2018

Targeted Imaging of the Atypical Chemokine Receptor 3 (ACKR3/CXCR7) in Human Cancer Xenografts.

scientific article published on 23 February 2016

Targeting NOTCH activation in small cell lung cancer through LSD1 inhibition

scientific article published on 05 February 2019

ULK1 inhibition overcomes compromised antigen presentation and restores antitumor immunity in LKB1 mutant lung cancer

scientific article published on 17 May 2021

Unravelling the biology of SCLC: implications for therapy

scientific article published on 23 May 2017

Upregulation of MMP-2 by HMGA1 promotes transformation in undifferentiated, large-cell lung cancer.

scientific article

Virus-Receptor Interactions and Virus Neutralization: Insights for Oncolytic Virus Development

scientific article published on 06 March 2020

Virus-Receptor Interactions: Structural Insights For Oncolytic Virus Development

scientific article published on 29 October 2019

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