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List of works by Doris Kretzschmar

A translational continuum of model systems for evaluating treatment strategies in Alzheimer's disease: isradipine as a candidate drug.

scientific article

Age-dependent neurodegeneration and Alzheimer-amyloid plaque formation in transgenic Drosophila.

scientific article published in April 2004

Amyloid precursor proteins are protective in Drosophila models of progressive neurodegeneration ⬇️

scientific article published on January 10, 2012

Analysis of amyloid precursor protein function in Drosophila melanogaster

scientific article published on 13 September 2011

Deregulation of the Egfr/Ras signaling pathway induces age-related brain degeneration in the Drosophila mutant vap.

scientific article

Drosophila GGA model: an ultimate gateway to GGA analysis

scientific article published on 13 October 2011

Glial and neuronal expression of polyglutamine proteins induce behavioral changes and aggregate formation in Drosophila.

scientific article published in January 2005

Identification of novel 1,4-benzoxazine compounds that are protective in tissue culture and in vivo models of neurodegeneration.

scientific article

Increased RhoA Prenylation in the loechrig (loe) Mutant Leads to Progressive Neurodegeneration ⬇️

scientific article published on September 6, 2012

Increased actin polymerization and stabilization interferes with neuronal function and survival in the AMPKγ mutant Loechrig.

scientific article

Loss of Swiss cheese/neuropathy target esterase activity causes disruption of phosphatidylcholine homeostasis and neuronal and glial death in adult Drosophila

scientific article published in March 2005

Loss of Tau results in defects in photoreceptor development and progressive neuronal degeneration in Drosophila.

scientific article published on 18 June 2014

Loss of circadian clock accelerates aging in neurodegeneration-prone mutants.

scientific article published on 27 December 2011

Loss-of-function mutations in PNPLA6 encoding neuropathy target esterase underlie pubertal failure and neurological deficits in Gordon Holmes syndrome

scientific article

Manipulations of amyloid precursor protein cleavage disrupt the circadian clock in aging Drosophila.

scientific article

Mutations in γ adducin are associated with inherited cerebral palsy.

scientific article published on December 2013

NTE/PNPLA6 is expressed in mature Schwann cells and is required for glial ensheathment of Remak fibers.

scientific article

Neurodegenerative mutants in Drosophila: a means to identify genes and mechanisms involved in human diseases?

scientific article

Optomotor-blind expression in glial cells is required for correct axonal projection across the Drosophila inner optic chiasm.

scientific article published on 22 October 2007

Organophosphate-induced changes in the PKA regulatory function of Swiss Cheese/NTE lead to behavioral deficits and neurodegeneration

scientific article (publication date: 2014)

Relationships between the circadian system and Alzheimer's disease-like symptoms in Drosophila

scientific article

Swiss Cheese, a protein involved in progressive neurodegeneration, acts as a noncanonical regulatory subunit for PKA-C3.

scientific article published on October 2008

Swiss cheese et allii, some of the first neurodegenerative mutants isolated in Drosophila.

scientific article published on 07 January 2009

The Drosophila carbonyl reductase sniffer prevents oxidative stress-induced neurodegeneration.

scientific article published in May 2004

β-Secretase Cleavage of the Fly Amyloid Precursor Protein Is Required for Glial Survival ⬇️

scientific article published on November 14, 2012

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