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List of works by Judith Bovée

A chondrogenic gene expression signature in mesenchymal stem cells is a classifier of conventional central chondrosarcoma.

scientific article

A murine mesenchymal stem cell model for initiating events in osteosarcomagenesis points to CDK4/CDK6 inhibition as a therapeutic target

scientific article published on 17 December 2021

A reappraisal of hemangiopericytoma of bone; analysis of cases reclassified as synovial sarcoma and solitary fibrous tumor of bone

scientific article

A translocation t(6;14) in two cases of leiomyosarcoma: Molecular cytogenetic and array-based comparative genomic hybridization characterization.

scientific article

An update of diagnostic strategies using molecular genetic and magnetic resonance imaging techniques for musculoskeletal tumors.

scientific article

Analysis of PD-L1, T-cell infiltrate and HLA expression in chondrosarcoma indicates potential for response to immunotherapy specifically in the dedifferentiated subtype.

scientific article published on 17 June 2016

Array CGH analysis identifies two distinct subgroups of primary angiosarcoma of bone

article

Array-comparative genomic hybridization of central chondrosarcoma: identification of ribosomal protein S6 and cyclin-dependent kinase 4 as candidate target genes for genomic aberrations.

scientific article published on July 2006

Aven-mediated checkpoint kinase control regulates proliferation and resistance to chemotherapy in conventional osteosarcoma.

scientific article

BMP and TGFbeta pathways in human central chondrosarcoma: enhanced endoglin and Smad 1 signaling in high grade tumors

scientific article

Bcl-xl as the most promising Bcl-2 family member in targeted treatment of chondrosarcoma

scientific article published on 21 September 2018

Beyond the Influence of <i>IDH</i> Mutations: Exploring Epigenetic Vulnerabilities in Chondrosarcoma

scientific article published on 30 November 2020

Brain Region-Specific Dynamics of On-Tissue Protein Digestion Using MALDI Mass Spectrometry Imaging

scientific article published on 6 November 2015

CORR Insights(®): Transcriptional Profiling Identifies the Signaling Axes of IGF and Transforming Growth Factor-β as Involved in the Pathogenesis of Osteosarcoma

scientific article

CT-guided, COBRA-FISH-assisted diagnosis of well-differentiated liposarcoma (inflammatory subtype) of the retroperitoneum.

scientific article published in September 2007

CTNNB1 45F mutation is a molecular prognosticator of increased postoperative primary desmoid tumor recurrence: an independent, multicenter validation study.

scientific article published on 31 July 2013

Carbon and Sulfur Cycling below the Chemocline in a Meromictic Lake and the Identification of a Novel Taxonomic Lineage in the FCB Superphylum, Candidatus Aegiribacteria.

scientific article

Cartilage tumour progression is characterized by an increased expression of heparan sulphate 6O-sulphation-modifying enzymes ⬇️

scientific article published on August 18, 2012

Cartilage tumours and bone development: molecular pathology and possible therapeutic targets.

scientific article published on 10 June 2010

Cell cycle deregulation and mosaic loss of Ext1 drive peripheral chondrosarcomagenesis in the mouse and reveal an intrinsic cilia deficiency

scientific article

Chemotherapy induces stemness in osteosarcoma cells through activation of Wnt/β-catenin signaling

scientific article published on 11 November 2015

Chondromyxoid fibroma resembles in vitro chondrogenesis, but differs in expression of signalling molecules

scientific article published on 01 June 2005

Chondrosarcoma is not characterized by detectable telomerase activity

scientific article published on 01 March 2001

Chondrosarcoma of the phalanx: a locally aggressive lesion with minimal metastatic potential: a report of 35 cases and a review of the literature.

scientific article

Chromosome 9 alterations and trisomy 22 in central chondrosarcoma: a cytogenetic and DNA flow cytometric analysis of chondrosarcoma subtypes

scientific article published on 01 December 2001

Clonal evolution through loss of chromosomes and subsequent polyploidization in chondrosarcoma

scientific article

Comprehensive analysis of published studies involving systemic treatment for chondrosarcoma of bone between 2000 and 2013.

scientific article

Conventional chondrosarcoma with focal clear cell change: a clinicopathological and molecular analysis

scientific article published on 13 September 2019

Correction: Clonal Evolution through Loss of Chromosomes and Subsequent Polyploidization in Chondrosarcoma

Correlation of hypoxic signalling to histological grade and outcome in cartilage tumours

scientific article published on 01 April 2010

Current State and Future Challenges of Mass Spectrometry Imaging for Clinical Research

scientific article published on 7 April 2015

DOG1 expression in giant-cell-containing bone tumours

scientific article published on 21 December 2015

Decreased EXT expression and intracellular accumulation of heparan sulphate proteoglycan in osteochondromas and peripheral chondrosarcomas.

scientific article published in March 2007

Dedifferentiated peripheral chondrosarcomas: regulation of EXT-downstream molecules and differentiation-related genes

scientific article published on 04 September 2009

Deletions of the long arm of chromosome 10 in progression of follicular thyroid tumors

scientific article published on 01 March 1996

Diagnosis and prognosis of chondrosarcoma of bone.

scientific article

Diagnostic and prognostic implications of the unfolding molecular biology of bone and soft tissue tumours

scientific article

Digital fibromyxoma (superficial acral fibromyxoma): a detailed characterization of 124 cases

scientific article

Distinct histological features characterize primary angiosarcoma of bone

scientific article published on 01 January 2011

Dose Reduction of Preoperative Radiotherapy in Myxoid Liposarcoma: A Nonrandomized Controlled Trial

scientific article published on 12 November 2020

EGFR and KRAS quality assurance schemes in pathology: generating normative data for molecular predictive marker analysis in targeted therapy.

scientific article

EXT-mutation analysis and loss of heterozygosity in sporadic and hereditary osteochondromas and secondary chondrosarcomas.

scientific article

EXT-related pathways are not involved in the pathogenesis of dysplasia epiphysealis hemimelica and metachondromatosis

scientific article published on 01 July 2006

EXTra hit for mouse osteochondroma.

scientific article

Enchondromatosis (Ollier disease, Maffucci syndrome) is not caused by the PTHR1 mutation p.R150C.

scientific article

Enchondromatosis: insights on the different subtypes.

scientific article

Epigenetic loss of the familial tumor-suppressor gene exostosin-1 (EXT1) disrupts heparan sulfate synthesis in cancer cells

scientific article published on 22 September 2004

Establishment and characterization of a new human myxoid liposarcoma cell line (DL-221) with the FUS-DDIT3 translocation.

scientific article published on 06 June 2016

Evaluation of response after neoadjuvant treatment in soft tissue sarcomas; the European Organization for Research and Treatment of Cancer-Soft Tissue and Bone Sarcoma Group (EORTC-STBSG) recommendations for pathological examination and reporting.

scientific article published on 14 December 2015

Evaluation of response after pre-operative radiotherapy in soft tissue sarcomas; the European Organisation for Research and Treatment of Cancer-Soft Tissue and Bone Sarcoma Group (EORTC-STBSG) and Imaging Group recommendations for radiological exami

scientific article published on 20 January 2016

Ewing sarcoma: The clinical relevance of the insulin-like growth factor 1 and the poly-ADP-ribose-polymerase pathway.

scientific article

Expression of cartilage growth plate signalling molecules in chondroblastoma.

scientific article published in January 2004

Expression of growth factors and their receptors in adamantinoma of long bones and the implication for its histogenesis

scientific article published on 01 January 1998

Expression of the immune regulation antigen CD70 in osteosarcoma

scientific article

Extra-abdominal subcutaneous metastasis of a gastrointestinal stromal tumor: report of a case and a review of the literature.

scientific article published on 06 October 2008

FUS rearrangements are rare in ‘pure’ sclerosing epithelioid fibrosarcoma

Frequent mutated B2M, EZH2, IRF8, and TNFRSF14 in primary bone diffuse large B-cell lymphoma reflect a GCB phenotype

scientific article published on 01 October 2021

Functional profiling of receptor tyrosine kinases and downstream signaling in human chondrosarcomas identifies pathways for rational targeted therapy.

scientific article published on 28 May 2013

Fusion events lead to truncation of FOS in epithelioid hemangioma of bone

scientific article

GRM1 is upregulated through gene fusion and promoter swapping in chondromyxoid fibroma.

scientific article

Genes involved in the osteoarthritis process identified through genome wide expression analysis in articular cartilage; the RAAK study.

scientific article

Genetic characterization of mesenchymal, clear cell, and dedifferentiated chondrosarcoma.

scientific article

Genomic profiling of chondrosarcoma: chromosomal patterns in central and peripheral tumors.

scientific article published on 31 March 2009

Hierarchical clustering of flow cytometry data for the study of conventional central chondrosarcoma.

scientific article

High nuclear expression of proteasome activator complex subunit 1 predicts poor survival in soft tissue leiomyosarcomas.

scientific article published on October 2016

High-grade sarcoma diagnosis and prognosis: Biomarker discovery by mass spectrometry imaging

scientific article

High-grade soft tissue sarcomas of the extremities: surgical margins influence only local recurrence not overall survival.

scientific article published on 7 March 2015

Histological findings in unclassified sudden infant death, including sudden infant death syndrome.

scientific article published on 18 January 2013

Histology-Guided High-Resolution Matrix-Assisted Laser Desorption Ionization Mass Spectrometry Imaging

scientific article published on 23 November 2015

Identification and systematic annotation of tissue-specific differentially methylated regions using the Illumina 450k array

scientific article published on 06 August 2013

Identification of a novel, recurrent HEY1-NCOA2 fusion in mesenchymal chondrosarcoma based on a genome-wide screen of exon-level expression data

scientific article

Identification of an EWS-pseudogene using translocation detection by RT-PCR in Ewing's sarcoma.

scientific article

Imaging mass spectrometry-based molecular histology differentiates microscopically identical and heterogeneous tumors

scientific article

Immune checkpoint inhibitors in sarcomas: in quest of predictive biomarkers

scientific article published on 20 November 2017

In reply

Inactivation of SDH and FH cause loss of 5hmC and increased H3K9me3 in paraganglioma/pheochromocytoma and smooth muscle tumors.

scientific article published on 12 October 2015

Incidence, predictive factors, and prognosis of chondrosarcoma in patients with Ollier disease and Maffucci syndrome: an international multicenter study of 161 patients

scientific article published on 6 December 2011

Increased infiltration of M2-macrophages, T-cells and PD-L1 expression in high grade leiomyosarcomas supports immunotherapeutic strategies

scientific article published on 26 October 2017

Increased type II deiodinase protein in OA-affected cartilage and allelic imbalance of OA risk polymorphism rs225014 at DIO2 in human OA joint tissues

scientific article published on 04 April 2012

Inhibition of Bcl-2 family members sensitises soft tissue leiomyosarcomas to chemotherapy

scientific article published on 3 May 2016

Inhibition of PARP Sensitizes Chondrosarcoma Cell Lines to Chemo- and Radiotherapy Irrespective of the IDH1 or IDH2 Mutation Status

scientific article published on 02 December 2019

Inhibition of mutant IDH1 decreases D-2-HG levels without affecting tumorigenic properties of chondrosarcoma cell lines.

scientific article

Interobserver reliability in the histopathological diagnosis of cartilaginous tumors in patients with multiple osteochondromas ⬇️

scientific article published on 04 May 2012

Intronic deletion and duplication proximal of the EXT1 gene: a novel causative mechanism for multiple osteochondromas.

scientific article published on 23 January 2013

Kinome profiling of chondrosarcoma reveals SRC-pathway activity and dasatinib as option for treatment.

scientific article

Kinome profiling of myxoid liposarcoma reveals NF-kappaB-pathway kinase activity and casein kinase II inhibition as a potential treatment option.

scientific article published on 23 September 2010

Linkage-Specific in Situ Sialic Acid Derivatization for N-Glycan Mass Spectrometry Imaging of Formalin-Fixed Paraffin-Embedded Tissues.

scientific article

Long-term clinical outcome of patients with soft tissue sarcomas treated with limb-sparing surgery and postoperative radiotherapy

scientific article published on 30 August 2012

Loss of H3K27 tri-methylation is a diagnostic marker for malignant peripheral nerve sheath tumors and an indicator for an inferior survival

scientific article published on 01 September 2016

Loss of H3K27 tri-methylation is a diagnostic marker for malignant peripheral nerve sheath tumors and an indicator for an inferior survival.

scientific article published on 18 March 2016

Loss of NF2 defines a genetic subgroup of non-FOS-rearranged osteoblastoma

scientific article published on 16 June 2020

Loss of heterozygosity and DNA ploidy point to a diverging genetic mechanism in the origin of peripheral and central chondrosarcoma

scientific article published on 01 November 1999

Loss-of-function mutations in PTPN11 cause metachondromatosis, but not Ollier disease or Maffucci syndrome

scientific article

Lymphatic and other vascular malformative/overgrowth disorders are caused by somatic mutations in PIK3CA

scientific article

MAP2K1 and MAP3K1 mutations in Langerhans cell histiocytosis.

scientific article

MEK inhibition induces apoptosis in osteosarcoma cells with constitutive ERK1/2 phosphorylation.

scientific article

Machine learning analysis of gene expression data reveals novel diagnostic and prognostic biomarkers and identifies therapeutic targets for soft tissue sarcomas

article

Maffucci syndrome: a genome-wide analysis using high resolution single nucleotide polymorphism and expression arrays on four cases.

scientific article published on 16 May 2011

Malignant fibrous histiocytoma and fibrosarcoma of bone: a re-assessment in the light of currently employed morphological, immunohistochemical and molecular approaches.

scientific article published on 22 September 2012

Malignant progression in multiple enchondromatosis (Ollier's disease): an autopsy-based molecular genetic study

scientific article published on 01 October 2000

Matrix biochemistry and cell biology of dedifferentiated chondrosarcomas

scientific article published on 01 May 2010

Molecular Pathology of Bone Tumors

scientific article published on 18 December 2018

Molecular genetic characterization of both components of a dedifferentiated chondrosarcoma, with implications for its histogenesis

scientific article published on 01 December 1999

Molecular oncogenesis of chondrosarcoma: impact for targeted treatment.

scientific article published on 10 May 2016

Molecular pathology and its diagnostic use in bone tumors.

scientific article

Molecular pathology of sarcomas: concepts and clinical implications

scientific article

Molecular phenotype is associated with survival in breast cancer patients with spinal bone metastases.

scientific article published on 31 October 2014

Molecular signatures of tumor progression in myxoid liposarcoma identified by N-glycan mass spectrometry imaging

scientific article published on 27 April 2020

Multimodal Mass Spectrometry Imaging of N-Glycans and Proteins from the Same Tissue Section

scientific article

Multiple osteochondromas

scientific article

Multiple osteochondromas: clinicopathological and genetic spectrum and suggestions for clinical management

scientific article

Multiple statistical analysis techniques corroborate intratumor heterogeneity in imaging mass spectrometry datasets of myxofibrosarcoma

scientific article

Mutation Analysis of H3F3A and H3F3B as a Diagnostic Tool for Giant Cell Tumor of Bone and Chondroblastoma

article

Mutation-driven epigenetic alterations as a defining hallmark of central cartilaginous tumours, giant cell tumour of bone and chondroblastoma

scientific article published on 14 November 2019

Mutations in the Isocitrate Dehydrogenase Genes IDH1 and IDH2 in Tumors ⬇️

scientific article published on January 1, 2013

Mutations of codon 918 in the RET proto-oncogene correlate to poor prognosis in sporadic medullary thyroid carcinomas

scientific article published on 01 October 1995

Myxoid tumours of soft tissue: the so-called myxoid extracellular matrix is heterogeneous in composition.

scientific article published in March 2008

NR4A3 rearrangement reliably distinguishes between the clinicopathologically overlapping entities myoepithelial carcinoma of soft tissue and cellular extraskeletal myxoid chondrosarcoma.

scientific article

NRAS mutations are more prevalent than KIT mutations in melanoma of the female urogenital tract--a study of 24 cases from the Netherlands

scientific article published on 5 May 2014

NY-ESO-1 (CTAG1B) expression in mesenchymal tumors

scientific article published on 21 November 2014

Near-haploidy and subsequent polyploidization characterize the progression of peripheral chondrosarcoma.

scientific article published in November 2000

No haploinsufficiency but loss of heterozygosity for EXT in multiple osteochondromas

scientific article

No preclinical rationale for IGF1R directed therapy in chondrosarcoma of bone

scientific article

Non-ossifying fibroma: A RAS-MAPK driven benign bone neoplasm

scientific article published on 20 March 2019

Opening the archives for state of the art tumour genetic research: sample processing for array-CGH using decalcified, formalin-fixed, paraffin-embedded tissue-derived DNA samples

scientific article

Osteosarcoma Stem Cells Have Active Wnt/β-catenin and Overexpress SOX2 and KLF4.

scientific article published on 2 September 2015

Osteosarcoma of the femur with skip, lymph node, and lung metastases

scientific article published on 01 January 2008

Outcome of advanced, unresectable conventional central chondrosarcoma.

scientific article published on 3 July 2014

PRAME and HLA Class I expression patterns make synovial sarcoma a suitable target for PRAME specific T-cell receptor gene therapy

article

Panobinostat-A Potential Treatment for Metastasized Ewing Sarcoma? A Case Report

scientific article published on 01 June 2016

Parent-of-origin tumourigenesis is mediated by an essential imprinted modifier in SDHD-linked paragangliomas: SLC22A18 and CDKN1C are candidate tumour modifiers

scientific article published on 8 July 2016

Periosteal chondrosarcoma: a histopathological and molecular analysis of a rare chondrosarcoma subtype.

scientific article published on 4 February 2015

Peripheral chondrosarcoma progression is accompanied by decreased Indian Hedgehog signalling.

scientific article

Pharmacological inhibition of Bcl-xL sensitizes osteosarcoma to doxorubicin

scientific article

Pitfalls in pathology of soft tissue sarcomas.

scientific article published in January 2004

Primary Ewing sarcoma of the iris.

scientific article published on 16 August 2013

Primary cilia organization reflects polarity in the growth plate and implies loss of polarity and mosaicism in osteochondroma

scientific article published on 26 April 2010

Primary vascular tumors of bone: a spectrum of entities?

scientific article

Prognostic Significance of Immunohistochemical Markers and Genetic Alterations in Malignant Peripheral Nerve Sheath Tumors: A Systematic Review

scientific article published on 22 December 2020

R132C IDH1 Mutations Are Found in Spindle Cell Hemangiomas and Not in Other Vascular Tumors or Malformations

Radiation-induced Sarcomas Occurring in Desmoid-type Fibromatosis Are Not Always Derived From the Primary Tumor

scientific article published in December 2015

Radiotherapy resistance in chondrosarcoma cells; a possible correlation with alterations in cell cycle related genes.

scientific article published on 28 May 2019

Re. Review article entitled 'The neoplastic pathogenesis of solitary and multiple osteochondromas'

scientific article published on 01 March 2000

Reclassification and subtyping of so-called malignant fibrous histiocytoma of bone: comparison with cytogenetic features

scientific article

Restoration of chemosensitivity for doxorubicin and cisplatin in chondrosarcoma in vitro: BCL-2 family members cause chemoresistance

scientific article published on 23 November 2011

Ring chromosome 4 as the sole cytogenetic anomaly in a chondroblastoma: a case report and review of the literature.

scientific article

Screening for potential targets for therapy in mesenchymal, clear cell, and dedifferentiated chondrosarcoma reveals Bcl-2 family members and TGFβ as potential targets.

scientific article

Secondary peripheral chondrosarcoma evolving from osteochondroma as a result of outgrowth of cells with functional EXT

scientific article (publication date: March 2012)

Serum levels of IGF-1 and IGF-BP3 are associated with event-free survival in adult Ewing sarcoma patients treated with chemotherapy

scientific article published on 13 June 2017

Single-Center Experience with Ifosfamide Monotherapy as Second-Line Treatment of Recurrent/Metastatic Osteosarcoma

scientific article published on 19 December 2019

Somatic activating ARAF mutations in Langerhans cell histiocytosis.

scientific article published on 20 March 2014

TM-04A TRANSGENIC ZEBRAFISH MODEL FOR GLIOMAS WITH MUTATIONS IN ISOCITRATE DEHYDROGENASE 1

Targeting survivin as a potential new treatment for chondrosarcoma of bone

scientific article published on 9 May 2016

Telatinib Is an Effective Targeted Therapy for Pseudomyogenic Hemangioendothelioma.

scientific article

The Role of EXT1 in Nonhereditary Osteochondroma: Identification of Homozygous Deletions

article

The clinical approach toward giant cell tumor of bone

scientific article

The clinical approach towards chondrosarcoma

scientific article

The molecular and cellular basis of exostosis formation in hereditary multiple exostoses

scientific article published on 01 April 2009

The role of metabolic enzymes in mesenchymal tumors and tumor syndromes: genetics, pathology, and molecular mechanisms.

scientific article published on 16 January 2018

The role of noncartilage-specific molecules in differentiation of cartilaginous tumors: lessons from chondroblastoma and chondromyxoid fibroma.

scientific article

The use of Bcl-2 and PTHLH immunohistochemistry in the diagnosis of peripheral chondrosarcoma in a clinicopathological setting

scientific article published on 03 March 2005

Three new chondrosarcoma cell lines: one grade III conventional central chondrosarcoma and two dedifferentiated chondrosarcomas of bone

scientific article

Tiling resolution array-CGH shows that somatic mosaic deletion of the EXT gene is causative in EXT gene mutation negative multiple osteochondromas patients

article

Tissue factor associates with survival and regulates tumour progression in osteosarcoma.

scientific article

Up-regulation of PTHrP and Bcl-2 expression characterizes the progression of osteochondroma towards peripheral chondrosarcoma and is a late event in central chondrosarcoma

scientific article published on 01 December 2000

Update on hypoxia-inducible factors and hydroxylases in oxygen regulatory pathways: from physiology to therapeutics

scientific article published on 15 March 2017

Utility of FOS as diagnostic marker for osteoid osteoma and osteoblastoma

scientific article published on 25 November 2019

Validation of a novel risk score to predict early and late recurrence in solitary fibrous tumour

scientific article published in 2022

Vascular Tumor Recapitulated in Endothelial Cells from hiPSCs Engineered to Express the <i>SERPINE1-FOSB</i> Translocation

scientific article published on 22 December 2020

Vascular tumors of bone: imaging findings.

scientific article

What's new in bone forming tumours of the skeleton?

scientific article published on 18 November 2019

[From gene to disease; hereditary multiple exostoses]

scientific article published on 01 January 2002

[Molecular biology diagnosis of tumors of the musculoskeletal system]

scientific article published on 01 December 1997

cDNA expression profiling of chondrosarcomas: Ollier disease resembles solitary tumours and alteration in genes coding for components of energy metabolism occurs with increasing grade.

scientific article

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