List of works - Fabio Malavasi

3,3',5'-Triiodothyronine concentrations in amniotic fluid at different stages of pregnancy

scientific article published on 01 April 1979

A CD38/CD203a/CD73 ectoenzymatic pathway independent of CD39 drives a novel adenosinergic loop in human T lymphocytes

scientific article published on 26 September 2013

A Murine, Bispecific Monoclonal Antibody Simultaneously Recognizing β-Glucan and MP65 Determinants in Candida Species

scientific article published on 9 February 2016

A highly immunogenic recombinant and truncated protein of the secreted aspartic proteases family (rSap2t) of Candida albicans as a mucosal anticandidal vaccine

scientific article published on 28 April 2011

A non-canonical adenosinergic pathway led by CD38 in human melanoma cells induces suppression of T cell proliferation

scientific article published on 25 July 2015

A novel role of the CX3CR1/CX3CL1 system in the cross-talk between chronic lymphocytic leukemia cells and tumor microenvironment.

scientific article

A panel of monoclonal antibodies recognizing GPI-anchored ADP-ribosyltransferase ART4, the carrier of the Dombrock blood group antigens.

scientific article published in July 2005

A single protein immunologically identified as CD38 displays NAD+ glycohydrolase, ADP-ribosyl cyclase and cyclic ADP-ribose hydrolase activities at the outer surface of human erythrocytes

scientific article published on 01 November 1993

A solid phase enzyme immunoassay for the measurement of urinary albumin and the detection of microalbuminuria

scientific article published on 01 April 1987

A variant of the LRP4 gene affects the risk of chronic lymphocytic leukaemia transformation to Richter syndrome

article

All-trans retinoic acid upregulates reduced CD38 transcription in lymphoblastoid cell lines from Autism spectrum disorder

scientific article

Analysis of the human CD36 leucocyte differentiation antigen by means of the monoclonal antibody NL07

scientific article published on 01 October 1991

Analysis of the physical association between CD38 and functional molecules expressed by human lymphocytes

scientific article published on 01 September 1992

Anti-CD38 antibody therapy: windows of opportunity yielded by the functional characteristics of the target molecule

scientific article

Anti-CD38 autoantibodies: characterisation in new-onset type I diabetes and latent autoimmune diabetes of the adult (LADA) and comparison with other islet autoantibodies.

scientific article published on 24 October 2002

Antigen-induced clustering of surface CD38 and recruitment of intracellular CD38 to the immunologic synapse

scientific article published on 22 January 2008

Antigenic characterization of recombinant, lymphoblastoid, and leukocyte IFN-alpha by monoclonal antibodies

scientific article published on 01 April 1999

Are retinoids potential therapeutic agents in disorders of social cognition including autism?

scientific article published on 06 May 2011

Arsenic trioxide and breast cancer: analysis of the apoptotic, differentiative and immunomodulatory effects

scientific article published in May 2002

Bf polymorphism and ankylosing spondylitis

scientific article published on 01 July 1978

Bf polymorphism and juvenile rheumatoid arthritis

scientific article published on 01 December 1985

Biosensor analysis of antigen-antibody interactions as a priority step in the generation of monoclonal bispecific antibodies

scientific article published on 01 January 1994

CD Nomenclature 2015: Human Leukocyte Differentiation Antigen Workshops as a Driving Force in Immunology

scientific article published on November 2015

CD molecules 2005: human cell differentiation molecules.

scientific article

CD molecules 2006--human cell differentiation molecules.

scientific article published on 4 December 2006

CD157 at the intersection between leukocyte trafficking and epithelial ovarian cancer invasion.

scientific article published on January 2014

CD157 is an important mediator of neutrophil adhesion and migration

scientific journal article

CD157 plays a pivotal role in neutrophil transendothelial migration

scientific article published on 17 August 2006

CD38 and CD100 lead a network of surface receptors relaying positive signals for B-CLL growth and survival

scientific article

CD38 and CD157: a long journey from activation markers to multifunctional molecules

scientific journal article

CD38 and ZAP-70 are functionally linked and mark CLL cells with high migratory potential

scientific article published on 15 August 2007

CD38 and behavior: moving from correlation to causality?

scientific article published on 01 August 2012

CD38 and bone marrow microenvironment.

scientific article published on January 2014

CD38 as a molecular compass guiding topographical decisions of chronic lymphocytic leukemia cells

scientific article published on 09 September 2010

CD38 at the junction between prognostic marker and therapeutic target.

scientific article published on 09 April 2008

CD38 gene polymorphism and chronic lymphocytic leukemia: a role in transformation to Richter syndrome?

scientific article published on 18 April 2008

CD38 in chronic lymphocytic leukemia: from bench to bedside?

scientific article published in June 2011

CD38 increases CXCL12-mediated signals and homing of chronic lymphocytic leukemia cells.

scientific article published on 11 March 2010

CD38 is a marker of human lacteals

scientific article published on 31 July 2002

CD38 is a signaling molecule in B-cell chronic lymphocytic leukemia cells

scientific article published on 22 May 2003

CD38 is associated with lipid rafts and upon receptor stimulation leads to Akt/protein kinase B and Erk activation in the absence of the CD3-zeta immune receptor tyrosine-based activation motifs.

scientific article

CD38 ligation in peripheral blood mononuclear cells of myeloma patients induces release of protumorigenic IL-6 and impaired secretion of IFNγ cytokines and proliferation.

scientific article published on 30 December 2013

CD38 ligation induces discrete cytokine mRNA expression in human cultured lymphocytes

scientific article published on 01 May 1995

CD38 ligation plays a direct role in the induction of IL-1beta, IL-6, and IL-10 secretion in resting human monocytes

scientific article published on November 2002

CD38-Expressing Myeloid-Derived Suppressor Cells Promote Tumor Growth in a Murine Model of Esophageal Cancer

scientific article

CD38/CD31 interactions activate genetic pathways leading to proliferation and migration in chronic lymphocytic leukemia cells

scientific article

CD38/CD31, the CCL3 and CCL4 chemokines, and CD49d/vascular cell adhesion molecule-1 are interchained by sequential events sustaining chronic lymphocytic leukemia cell survival

scientific article published on 21 April 2009

CD56brightCD16- NK Cells Produce Adenosine through a CD38-Mediated Pathway and Act as Regulatory Cells Inhibiting Autologous CD4+ T Cell Proliferation

scientific article published on 19 June 2015

CD73-generated extracellular adenosine in chronic lymphocytic leukemia creates local conditions counteracting drug-induced cell death

scientific article published on 13 October 2011

Characterization by monoclonal antibody of a highly conserved antigenic determinant expressed on human platelet membranes and intermediate filament type III.

scientific article published on May 1990

Characterization of a murine monoclonal antibody specific for human early lymphohemopoietic cells

scientific article published on 01 January 1984

Characterization of in vitro antibody-dependent cell-mediated cytotoxicity activity of therapeutic antibodies - impact of effector cells.

scientific article published on 3 April 2014

Chronic lymphocytic leukemia microenvironment: shifting the balance from apoptosis to proliferation.

scientific article published in June 2009

Clinical efficacy and management of monoclonal antibodies targeting CD38 and SLAMF7 in multiple myeloma.

scientific article

Cytosolic free calcium concentration in the mitogenic stimulation of T lymphocytes by anti-CD3 monoclonal antibodies.

scientific article published on September 1994

Death of T cell precursors in the human thymus: a role for CD38.

scientific article published in September 2003

Design and scaleup of downstream processing of monoclonal antibodies for cancer therapy: from research to clinical proof of principle.

scientific article published in April 2003

E2A is a transcriptional regulator of CD38 expression in chronic lymphocytic leukemia

scientific article published on 07 January 2011

Ectocellular CD38-catalyzed synthesis and intracellular Ca2+-signalling activity of cyclic ADP-ribose in T-lymphocytes are not functionally related

scientific article published on 01 November 1998

Ectoenzymes and innate immunity: the role of human CD157 in leukocyte trafficking.

scientific article published on January 2009

Ectonucleotidase Expression on Human Amnion Epithelial Cells: Adenosinergic Pathways and Dichotomic Effects on Immune Effector Cell Populations

scientific article published on 26 December 2018

Editorial: CD38 and retinoids: a step toward a cure

scientific article published on 01 August 2011

Evidence of an immunologic mechanism behind the therapeutical effects of arsenic trioxide (As(2)O(3)) on myeloma cells

scientific article published on 01 March 2001

Exosomes from human lymphoblastoid B cells express enzymatically active CD38 that is associated with signaling complexes containing CD81, Hsc-70 and Lyn

scientific article published on 04 June 2010

Expression of HLA class II determinants by normal and chronic myeloid leukemia progenitors

scientific article published on 01 January 1987

Expression of ribosomal and translation-associated genes is correlated with a favorable clinical course in chronic lymphocytic leukemia.

scientific article published on 27 November 2002

From cells to genes: how to make antibodies useful in human diagnosis and therapy.

scientific article published on January 1993

Functional effects of a monoclonal antibody directed against a distinct epitope on 4F2 molecular complex in human peripheral blood mononuclear cell activation.

scientific article published on August 1991

Functional topography of discrete domains of human CD38

scientific article published on 01 December 2000

Functional, structural, and distribution analysis of the chorionic gonadotropin receptor using murine monoclonal antibodies

scientific article published on November 2003

Generation and selection of monoclonal antibodies identifying surface molecules discriminating between fetal and adult fibroblasts

scientific article published on 01 January 1989

HLA-G is a component of the chronic lymphocytic leukemia escape repertoire to generate immune suppression: impact of the HLA-G 14 base pair (rs66554220) polymorphism

scientific article

Human CD38 and CD16 are functionally dependent and physically associated in natural killer cells.

scientific article published on April 2002

Human CD38: a glycoprotein in search of a function

scientific article

Identification and characterization of an active soluble form of human CD38 in normal and pathological fluids

scientific article published on 01 November 1996

Immunodetection of anti-MAG IgM antibody by cross-reactivity to LA-N-1 neuroblastoma cells.

scientific article published on April 2005

In-tandem insight from basic science combined with clinical research: CD38 as both marker and key component of the pathogenetic network underlying chronic lymphocytic leukemia.

scientific article

Increased CD38 expression in T cells and circulating anti-CD38 IgG autoantibodies differentially correlate with distinct cytokine profiles and disease activity in systemic lupus erythematosus patients.

scientific article published on 26 March 2013

Mechanism of Action of a New Anti-CD38 Antibody: Enhancing Myeloma Immunotherapy

scientific article published on 07 March 2019

Mechanism-based small molecule probes for labeling CD38 on live cells.

scientific article published in February 2009

Microplate selection technique (MPST)

scientific article published on 01 September 1989

Microvesicles expressing adenosinergic ectoenzymes and their potential role in modulating bone marrow infiltration by neuroblastoma cells

scientific article published on 19 February 2019

Monoclonal antibodies and therapy of human cancers

scientific article published on 01 August 2000

Murine monoclonal antibody recognizing a 90-kDa cell-surface determinant selectively lost by multi-drug-resistant variants of cem cells ⬇️

scientific article published on January 15, 1990

NAD+-metabolizing ecto-enzymes shape tumor-host interactions: the chronic lymphocytic leukemia model

scientific article published on 19 April 2011

New HLA antigenic determinant shared by A2 and a subtype of Bw16 molecules detected by a monoclonal antibody

scientific article published on 01 May 1983

Nicotinamide blocks proliferation and induces apoptosis of chronic lymphocytic leukemia cells through activation of the p53/miR-34a/SIRT1 tumor suppressor network

scientific article published on 12 May 2011

Novel Antitransferrin Receptor Antibodies Improve the Blood-Brain Barrier Crossing Efficacy of Immunoliposomes.

scientific article published on 13 January 2016

Novel targets for the treatment of relapsing multiple myeloma

scientific article published on 03 June 2019

Oct-4+/Tenascin C+ neuroblastoma cells serve as progenitors of tumor-derived endothelial cells.

scientific article

Peripheral blood CD38 expression predicts survival in B-cell chronic lymphocytic leukemia

scientific article published on 01 November 2001

Phosphorylation of c-Cbl and p85 PI3K driven by all-trans retinoic acid and CD38 depends on Lyn kinase activity.

scientific article

Prognostic significance of combined analysis of ZAP-70 and CD38 in chronic lymphocytic leukemia

scientific article published on 01 September 2007

Properdin factor B polymorphism in continental Italy and Sardinia

scientific article published on 01 January 1981

Radioimmunotherapy in advanced ovarian cancer: is there a role for pre-targeting with (90)Y-biotin?

scientific article

Rapid induction of CD38 antigen on myeloid leukemia cells by all trans-retinoic acid

scientific article published on 01 September 1993

Real-time kinetic analysis applied to the production of bispecific monoclonal antibodies for radioimmunodetection of cancer

scientific article published on 01 January 1993

Reduced expression of macrophage-associated antigens on alveolar mononuclear phagocytes from acquired immunodeficiency syndrome

scientific article published on 01 January 1993

Secretion of IFN-γ, IL-6, Granulocyte-Macrophage Colony-Stimulating Factor and IL-10 Cytokines after Activation of Human Purified T Lymphocytes upon CD38 Ligation

scientific article published on 01 November 1996

Selective high-performance liquid chromatographic purification of bispecific monoclonal antibodies

scientific article published on 01 May 1992

Stimulation of T cells via CD44 requires leukocyte-function-associated antigen interactions and interleukin-2 production

article

Structural, functional, and tissue distribution analysis of human transferrin receptor-2 by murine monoclonal antibodies and a polyclonal antiserum

scientific article

Targeting CD38 Enhances the Antileukemic Activity of Ibrutinib in Chronic Lymphocytic Leukemia

scientific article published on 02 April 2019

Targeting the microenvironment in chronic lymphocytic leukemia offers novel therapeutic options

scientific article published on 19 August 2012

TfR2 localizes in lipid raft domains and is released in exosomes to activate signal transduction along the MAPK pathway

scientific article published on 17 October 2006

The ADP-ribosyl cyclases--the current evolutionary state of the ARCs.

scientific article published on June 2014

The CD3-gamma delta epsilon transducing module mediates CD38-induced protein-tyrosine kinase and mitogen-activated protein kinase activation in Jurkat T cells.

scientific article published on July 1999

The CD49d/CD29 complex is physically and functionally associated with CD38 in B-cell chronic lymphocytic leukemia cells.

scientific article published on 6 January 2012

The PD-1/PD-L1 axis contributes to T-cell dysfunction in chronic lymphocytic leukemia.

scientific article published on 8 January 2013

The Role of Platelet/Endothelial Cell Adhesion Molecule 1 (CD31) and CD38 Antigens in Marrow Microenvironmental Retention of Acute Myelogenous Leukemia Cells

scientific article published on 01 September 2007

The cell death-inducing ability of glycoprotein 120 from different HIV strains correlates with their ability to induce CD4 lateral association with CD95 on CD4+ T cells

scientific article published on 01 September 1999

The hidden life of NAD+-consuming ectoenzymes in the endocrine system.

scientific article published on 21 July 2010

The human CD38 gene: polymorphism, CpG island, and linkage to the CD157 (BST-1) gene.

scientific article published in July 1999

The low-density lipoprotein receptor plays a role in the infection of primary human hepatocytes by hepatitis C virus.

scientific article published on 13 November 2006

Transferrin receptor 2 is frequently expressed in human cancer cell lines

article

Transferrin receptor 2 protein is not expressed in normal erythroid cells

scientific article published on August 2004

Two genetic variants of CD38 in subjects with autism spectrum disorder and controls.

scientific article published on May 2010

Unconventional, adenosine-producing suppressor T cells induced by dendritic cells exposed to BPZE1 pertussis vaccine

scientific article published on 18 June 2015

Unraveling the contribution of ectoenzymes to myeloma life and survival in the bone marrow niche.

scientific article

Use of genetic immunization to raise antibodies recognizing toxin-related cell surface ADP-ribosyltransferases in native conformation

scientific article published on July 2005

gp 120s derived from four syncytium-inducing HIV-1 strains induce different patterns of CD4 association with lymphocyte surface molecules

scientific article (publication date: August 1997)

List of works by Fabio Malavasi

3,3',5'-Triiodothyronine concentrations in amniotic fluid at different stages of pregnancy

A CD38/CD203a/CD73 ectoenzymatic pathway independent of CD39 drives a novel adenosinergic loop in human T lymphocytes

A Murine, Bispecific Monoclonal Antibody Simultaneously Recognizing β-Glucan and MP65 Determinants in Candida Species

A highly immunogenic recombinant and truncated protein of the secreted aspartic proteases family (rSap2t) of Candida albicans as a mucosal anticandidal vaccine

A non-canonical adenosinergic pathway led by CD38 in human melanoma cells induces suppression of T cell proliferation

A novel role of the CX3CR1/CX3CL1 system in the cross-talk between chronic lymphocytic leukemia cells and tumor microenvironment.

A panel of monoclonal antibodies recognizing GPI-anchored ADP-ribosyltransferase ART4, the carrier of the Dombrock blood group antigens.

A single protein immunologically identified as CD38 displays NAD+ glycohydrolase, ADP-ribosyl cyclase and cyclic ADP-ribose hydrolase activities at the outer surface of human erythrocytes

A solid phase enzyme immunoassay for the measurement of urinary albumin and the detection of microalbuminuria

A variant of the LRP4 gene affects the risk of chronic lymphocytic leukaemia transformation to Richter syndrome

All-trans retinoic acid upregulates reduced CD38 transcription in lymphoblastoid cell lines from Autism spectrum disorder

Analysis of the human CD36 leucocyte differentiation antigen by means of the monoclonal antibody NL07

Analysis of the physical association between CD38 and functional molecules expressed by human lymphocytes

Anti-CD38 antibody therapy: windows of opportunity yielded by the functional characteristics of the target molecule

Anti-CD38 autoantibodies: characterisation in new-onset type I diabetes and latent autoimmune diabetes of the adult (LADA) and comparison with other islet autoantibodies.

Antigen-induced clustering of surface CD38 and recruitment of intracellular CD38 to the immunologic synapse

Antigenic characterization of recombinant, lymphoblastoid, and leukocyte IFN-alpha by monoclonal antibodies

Are retinoids potential therapeutic agents in disorders of social cognition including autism?

Arsenic trioxide and breast cancer: analysis of the apoptotic, differentiative and immunomodulatory effects

Bf polymorphism and ankylosing spondylitis

Bf polymorphism and juvenile rheumatoid arthritis

Biosensor analysis of antigen-antibody interactions as a priority step in the generation of monoclonal bispecific antibodies

CD Nomenclature 2015: Human Leukocyte Differentiation Antigen Workshops as a Driving Force in Immunology

CD molecules 2005: human cell differentiation molecules.

CD molecules 2006--human cell differentiation molecules.

CD157 at the intersection between leukocyte trafficking and epithelial ovarian cancer invasion.

CD157 is an important mediator of neutrophil adhesion and migration

CD157 plays a pivotal role in neutrophil transendothelial migration

CD38 and CD100 lead a network of surface receptors relaying positive signals for B-CLL growth and survival

CD38 and CD157: a long journey from activation markers to multifunctional molecules

CD38 and ZAP-70 are functionally linked and mark CLL cells with high migratory potential

CD38 and behavior: moving from correlation to causality?

CD38 and bone marrow microenvironment.

CD38 as a molecular compass guiding topographical decisions of chronic lymphocytic leukemia cells

CD38 at the junction between prognostic marker and therapeutic target.

CD38 gene polymorphism and chronic lymphocytic leukemia: a role in transformation to Richter syndrome?

CD38 in chronic lymphocytic leukemia: from bench to bedside?

CD38 increases CXCL12-mediated signals and homing of chronic lymphocytic leukemia cells.

CD38 is a marker of human lacteals

CD38 is a signaling molecule in B-cell chronic lymphocytic leukemia cells

CD38 is associated with lipid rafts and upon receptor stimulation leads to Akt/protein kinase B and Erk activation in the absence of the CD3-zeta immune receptor tyrosine-based activation motifs.

CD38 ligation in peripheral blood mononuclear cells of myeloma patients induces release of protumorigenic IL-6 and impaired secretion of IFNγ cytokines and proliferation.

CD38 ligation induces discrete cytokine mRNA expression in human cultured lymphocytes

CD38 ligation plays a direct role in the induction of IL-1beta, IL-6, and IL-10 secretion in resting human monocytes

CD38-Expressing Myeloid-Derived Suppressor Cells Promote Tumor Growth in a Murine Model of Esophageal Cancer

CD38/CD31 interactions activate genetic pathways leading to proliferation and migration in chronic lymphocytic leukemia cells

CD38/CD31, the CCL3 and CCL4 chemokines, and CD49d/vascular cell adhesion molecule-1 are interchained by sequential events sustaining chronic lymphocytic leukemia cell survival

CD56brightCD16- NK Cells Produce Adenosine through a CD38-Mediated Pathway and Act as Regulatory Cells Inhibiting Autologous CD4+ T Cell Proliferation

CD73-generated extracellular adenosine in chronic lymphocytic leukemia creates local conditions counteracting drug-induced cell death

Characterization by monoclonal antibody of a highly conserved antigenic determinant expressed on human platelet membranes and intermediate filament type III.

Characterization of a murine monoclonal antibody specific for human early lymphohemopoietic cells

Characterization of in vitro antibody-dependent cell-mediated cytotoxicity activity of therapeutic antibodies - impact of effector cells.

Chronic lymphocytic leukemia microenvironment: shifting the balance from apoptosis to proliferation.

Clinical efficacy and management of monoclonal antibodies targeting CD38 and SLAMF7 in multiple myeloma.

Cytosolic free calcium concentration in the mitogenic stimulation of T lymphocytes by anti-CD3 monoclonal antibodies.

Death of T cell precursors in the human thymus: a role for CD38.

Design and scaleup of downstream processing of monoclonal antibodies for cancer therapy: from research to clinical proof of principle.

E2A is a transcriptional regulator of CD38 expression in chronic lymphocytic leukemia

Ectocellular CD38-catalyzed synthesis and intracellular Ca2+-signalling activity of cyclic ADP-ribose in T-lymphocytes are not functionally related

Ectoenzymes and innate immunity: the role of human CD157 in leukocyte trafficking.

Ectonucleotidase Expression on Human Amnion Epithelial Cells: Adenosinergic Pathways and Dichotomic Effects on Immune Effector Cell Populations

Editorial: CD38 and retinoids: a step toward a cure

Evidence of an immunologic mechanism behind the therapeutical effects of arsenic trioxide (As(2)O(3)) on myeloma cells

Exosomes from human lymphoblastoid B cells express enzymatically active CD38 that is associated with signaling complexes containing CD81, Hsc-70 and Lyn

Expression of HLA class II determinants by normal and chronic myeloid leukemia progenitors

Expression of ribosomal and translation-associated genes is correlated with a favorable clinical course in chronic lymphocytic leukemia.

From cells to genes: how to make antibodies useful in human diagnosis and therapy.

Functional effects of a monoclonal antibody directed against a distinct epitope on 4F2 molecular complex in human peripheral blood mononuclear cell activation.

Functional topography of discrete domains of human CD38

Functional, structural, and distribution analysis of the chorionic gonadotropin receptor using murine monoclonal antibodies

Generation and selection of monoclonal antibodies identifying surface molecules discriminating between fetal and adult fibroblasts

HLA-G is a component of the chronic lymphocytic leukemia escape repertoire to generate immune suppression: impact of the HLA-G 14 base pair (rs66554220) polymorphism

Human CD38 and CD16 are functionally dependent and physically associated in natural killer cells.

Human CD38: a glycoprotein in search of a function

Identification and characterization of an active soluble form of human CD38 in normal and pathological fluids

Immunodetection of anti-MAG IgM antibody by cross-reactivity to LA-N-1 neuroblastoma cells.

In-tandem insight from basic science combined with clinical research: CD38 as both marker and key component of the pathogenetic network underlying chronic lymphocytic leukemia.

Increased CD38 expression in T cells and circulating anti-CD38 IgG autoantibodies differentially correlate with distinct cytokine profiles and disease activity in systemic lupus erythematosus patients.

Mechanism of Action of a New Anti-CD38 Antibody: Enhancing Myeloma Immunotherapy