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List of works by Anthony J Hannan

'Super-Enrichment' Reveals Dose-Dependent Therapeutic Effects of Environmental Stimulation in a Transgenic Mouse Model of Huntington's Disease

scientific article published in January 2014

A Tale of Two Maladies? Pathogenesis of Depression with and without the Huntington's Disease Gene Mutation.

scientific article published on 09 July 2013

A neuroligin-3 mutation implicated in autism causes abnormal aggression and increases repetitive behavior in mice

scientific article

Activity-dependent regulation of synapse and dendritic spine morphology in developing barrel cortex requires phospholipase C-beta1 signalling

scientific article

Affective dysfunction in a mouse model of Rett syndrome: Therapeutic effects of environmental stimulation and physical activity

scientific article

Altered Amygdala Excitation and CB1 Receptor Modulation of Aggressive Behavior in the Neuroligin-3 Mouse Model of Autism

scientific article published on 03 August 2018

Anterior cingulate cortical transplantation in transgenic Huntington’s disease mice ⬇️

scientific article published on November 1, 2001

Antidepressant-Like Effect of the Norepinephrine-Dopamine Reuptake Inhibitor Bupropion in a Mouse Model of Huntington's Disease with Dopaminergic Dysfunction

scientific article published in January 2012

Assessing attention orienting in mice: a novel touchscreen adaptation of the Posner-style cueing task

scientific article published on 02 October 2020

Australian Neuroscience Society--24th annual meeting. 27-30 January 2004, Melbourne, Australia.

scientific article published in March 2004

Australian Neuroscience Society--25th Annual Meeting. 30 January-2 February 2005, Perth, Australia.

scientific article published in March 2005

Behavioural and molecular consequences of chronic cannabinoid treatment in Huntington's disease transgenic mice.

scientific article published on July 2010

Behavioural state differentially engages septohippocampal cholinergic and GABAergic neurons in R6/1 Huntington's disease mice.

scientific article

Beyond loss of frataxin: the complex molecular pathology of Friedreich ataxia

scientific article published on January 2014

Brain Cholesterol Synthesis and Metabolism is Progressively Disturbed in the R6/1 Mouse Model of Huntington's Disease: A Targeted GC-MS/MS Sterol Analysis.

scientific article published on 28 November 2015

Brain phylogeny, ontogeny and dysfunction: integrating evolutionary, developmental and clinical perspectives in cognitive neuroscience.

scientific article published on June 2007

British Neuroscience Association - 16th National Meeting. 8-11 April 2001, Harrogate, UK.

scientific article

CROC-4: a novel brain specific transcriptional activator of c-fos expressed from proliferation through to maturation of multiple neuronal cell types.

scientific article published in September 2000

Characterizing Social Behavior in Genetically Targeted Mouse Models of Brain Disorders ⬇️

scientific article published on January 1, 2013

Cognitive disorders and neurogenesis deficits in Huntington's disease mice are rescued by fluoxetine.

scientific article published in October 2005

Cognitive endophenotypes, gene-environment interactions and experience-dependent plasticity in animal models of schizophrenia.

scientific article published on 10 December 2015

Cortisol and depression in pre-diagnosed and early stage Huntington's disease

scientific article published on 26 September 2013

Decanalization mediating gene-environment interactions in schizophrenia and other psychiatric disorders with neurodevelopmental etiology.

scientific article

Decanalization, brain development and risk of schizophrenia ⬇️

scientific article published on June 28, 2011

Decreased expression of mGluR5 within the dorsolateral prefrontal cortex in autism and increased microglial number in mGluR5 knockout mice: Pathophysiological and neurobehavioral implications

scientific article published on 5 June 2015

Decreased hippocampal cell proliferation in R6/1 Huntington's mice.

scientific article published in April 2004

Deficits in experience-dependent cortical plasticity and sensory-discrimination learning in presymptomatic Huntington's disease mice.

scientific article published in March 2005

Deficits in spermatogenesis but not neurogenesis are alleviated by chronic testosterone therapy in R6/1 Huntington's disease mice.

scientific article

Dendritic spine pathology and deficits in experience-dependent dendritic plasticity in R6/1 Huntington's disease transgenic mice

scientific article published on May 2004

Depression-related behaviours displayed by female C57BL/6J mice during abstinence from chronic ethanol consumption are rescued by wheel-running.

scientific article published on 31 March 2013

Diet-Induced Modification of the Sperm Epigenome Programs Metabolism and Behavior

scientific article published on 16 November 2019

Differential effects of early environmental enrichment on emotionality related behaviours in Huntington's disease transgenic mice.

scientific article published on 8 October 2012

Differential effects of voluntary physical exercise on behavioral and brain-derived neurotrophic factor expression deficits in Huntington's disease transgenic mice.

scientific article published on 22 May 2006

Differential induction and intracellular localization of SCG10 messenger RNA is associated with neuronal differentiation.

scientific article published in June 1996

Dissecting cause and effect in the pathogenesis of psychiatric disorders: genes, environment and behaviour.

scientific article published on August 2007

Dissociating the therapeutic effects of environmental enrichment and exercise in a mouse model of anxiety with cognitive impairment.

scientific article published on 26 April 2016

Dynamic mutations as digital genetic modulators of brain development, function and dysfunction.

scientific article published on June 2007

Dysregulation of synaptic proteins, dendritic spine abnormalities and pathological plasticity of synapses as experience-dependent mediators of cognitive and psychiatric symptoms in Huntington's disease.

scientific article published on 24 May 2012

Editorial: Environmental Enrichment: Enhancing Neural Plasticity, Resilience, and Repair

scientific article published on 16 April 2019

Effect of enhanced voluntary physical exercise on brain levels of monoamines in Huntington disease mice

scientific article

Effects of aging on the motor, cognitive and affective behaviors, neuroimmune responses and hippocampal gene expression

scientific article published on 24 January 2020

Effects of chronic stress on the onset and progression of Huntington's disease in transgenic mice.

scientific article published in August 2014

Effects of enriched environment on animal models of neurodegenerative diseases and psychiatric disorders.

scientific article published on 15 May 2008

Effects of environmental manipulations in genetically targeted animal models of affective disorders.

scientific article published on 16 April 2012

Elevated paternal glucocorticoid exposure alters the small noncoding RNA profile in sperm and modifies anxiety and depressive phenotypes in the offspring.

scientific article

Elevated paternal glucocorticoid exposure modifies memory retention in female offspring.

scientific article published on 18 May 2017

Enhancement of cognitive function in models of brain disease through environmental enrichment and physical activity ⬇️

scientific article published on July 2, 2012

Enriched environments, experience-dependent plasticity and disorders of the nervous system.

scientific article published on September 2006

Enviromimetics: exploring gene environment interactions to identify therapeutic targets for brain disorders.

scientific article published on July 2007

Environmental Enrichment Ameliorates Behavioral Impairments Modeling Schizophrenia in Mice Lacking Metabotropic Glutamate Receptor 5

scientific article

Environmental Enrichment: A Cure for Cancer? It's All in the Mind ⬇️

scientific article published on September 15, 2010

Environmental enrichment and brain repair: harnessing the therapeutic effects of cognitive stimulation and physical activity to enhance experience-dependent plasticity

scientific article

Environmental enrichment as an experience-dependent modulator of social plasticity and cognition

scientific article published on 28 March 2019

Environmental enrichment enhances cognitive flexibility in C57BL/6 mice on a touchscreen reversal learning task

scientific article

Environmental enrichment reduces innate anxiety with no effect on depression-like behaviour in mice lacking the serotonin transporter.

scientific article published on 16 June 2017

Environmental enrichment reduces neuronal intranuclear inclusion load but has no effect on messenger RNA expression in a mouse model of Huntington disease

scientific article published in August 2010

Environmental enrichment rescues female-specific hyperactivity of the hypothalamic-pituitary-adrenal axis in a model of Huntington's disease

scientific article published on 24 July 2012

Environmental enrichment rescues protein deficits in a mouse model of Huntington's disease, indicating a possible disease mechanism.

scientific article

Environmental enrichment slows disease progression in R6/2 Huntington's disease mice

scientific article

Environmental factors as modulators of neurodegeneration: insights from gene-environment interactions in Huntington's disease.

scientific article published on 10 March 2015

Environmental modulations of the number of midbrain dopamine neurons in adult mice

scientific article

Epigenetic modifications in trinucleotide repeat diseases.

scientific article published on 14 August 2013

Epimimetics: Novel Therapeutics Targeting Epigenetic Mediators and Modulators

scientific article published on 30 January 2020

Ethological endophenotypes are altered by elevated stress hormone levels in both Huntington's disease and wildtype mice

scientific article published on 4 August 2014

European Neuroscience--Seventh Biennial FENS Forum.

scientific article published on September 2010

European neuroscience - Federation of European Neuroscience Societies 5th Forum. 8-12 July 2006, Vienna, Austria.

scientific article published in October 2006

Evaluation of attention in APP/PS1 mice shows impulsive and compulsive behaviours

scientific article published on 08 June 2019

Exercise alters mouse sperm small noncoding RNAs and induces a transgenerational modification of male offspring conditioned fear and anxiety.

scientific article published on 2 May 2017

Exercise, diet and stress as modulators of gut microbiota: Implications for neurodegenerative diseases

scientific article published on 16 October 2019

Exploring the efficacy of constraint in animal models of stroke: meta-analysis and systematic review of the current evidence

scientific article published on 19 June 2012

FENS 2000--Federation of European Neuroscience Societies. 24-28 June 2000, Brighton, UK

scientific article published on 01 October 2000

Gene-environment interactions and construct validity in preclinical models of psychiatric disorders.

scientific article published on 17 December 2010

Gene-environment interactions informing therapeutic approaches to cognitive and affective disorders

scientific article published on 22 December 2017

Gene-environment interactions modulating cognitive function and molecular correlates of synaptic plasticity in Huntington's disease transgenic mice.

scientific article

Gene-environment-gut interactions in Huntington's disease mice are associated with environmental modulation of the gut microbiome

scientific article published on 24 December 2021

Gut dysbiosis in Huntington's disease: associations among gut microbiota, cognitive performance and clinical outcomes

scientific article published on 24 July 2020

High stress hormone levels accelerate the onset of memory deficits in male Huntington's disease mice

scientific article published on 10 May 2014

High-Frequency Neuronal Oscillatory Abnormalities in the Phospholipase C-β1 Knockout Mouse Model of Schizophrenia

scientific article published on 01 March 2019

Hippocampal neurogenesis, cognitive deficits and affective disorder in Huntington's disease

scientific article

Huntington's Disease: Pathogenic Mechanisms and Therapeutic Targets.

scientific article

Hypersensitivity to sertraline in the absence of hippocampal 5-HT1AR and 5-HTT gene expression changes following paternal corticosterone treatment

scientific article published on 01 April 2018

Identifying novel interventional strategies for psychiatric disorders: integrating genomics, 'enviromics' and gene-environment interactions in valid preclinical models.

scientific article

Impaired basal and running-induced hippocampal neurogenesis coincides with reduced Akt signaling in adult R6/1 HD mice.

scientific article

Impaired learning-dependent cortical plasticity in Huntington's disease transgenic mice

scientific journal article

Impaired social behaviour and molecular mediators of associated neural circuits during chronic Toxoplasma gondii infection in female mice

scientific article published on 23 February 2019

International Brain Research Organization--Seventh World Congress of Neuroscience. 12-17 July 2007, Melbourne, Victoria, Australia.

scientific article published in October 2007

International Brain Research Organization--Sixth World Congress of Neuroscience. 10-15 July 2003, Prague, Czech Republic

scientific article published on September 1, 2003

Intracellular localization of tropomyosin mRNA and protein is associated with development of neuronal polarity.

scientific article

Investigating the relationships between hypothalamic volume and measures of circadian rhythm and habitual sleep in premanifest Huntington's disease.

scientific article published on 3 July 2018

Isoform specific differences in phospholipase C beta 1 expression in the prefrontal cortex in schizophrenia and suicide

scientific article

Localized changes to glycogen synthase kinase-3 and collapsin response mediator protein-2 in the Huntington's disease affected brain.

scientific article published on 14 March 2014

Long-term effects of combined neonatal and adolescent stress on brain-derived neurotrophic factor and dopamine receptor expression in the rat forebrain.

scientific article published on 23 August 2014

Loss of the Sexually Dimorphic Neuro-Inflammatory Response in a Transgenic Mouse Model of Huntington's Disease

scientific article published on 22 November 2015

Magnetic resonance imaging as an approach towards identifying neuropathological biomarkers for Huntington's disease

scientific article

Mechanisms mediating brain and cognitive reserve: experience-dependent neuroprotection and functional compensation in animal models of neurodegenerative diseases.

scientific article

Metabotropic glutamate receptors as targets for novel antipsychotic treatments.

scientific article published on June 2012

Microbiome profiling reveals gut dysbiosis in a transgenic mouse model of Huntington's disease

scientific article published on 05 September 2018

Molecular mechanisms mediating pathological plasticity in Huntington's disease and Alzheimer's disease

scientific article published on 8 January 2007

Molecular mediators, environmental modulators and experience-dependent synaptic dysfunction in Huntington's disease.

scientific article published in January 2004

Mutant huntingtin's effects on striatal gene expression in mice recapitulate changes observed in human Huntington's disease brain and do not differ with mutant huntingtin length or wild-type huntingtin dosage

scientific article

Mutation of Gtf2ird1 from the Williams–Beuren syndrome critical region results in facial dysplasia, motor dysfunction, and altered vocalisations ⬇️

scientific article published on December 11, 2011

Mutations in neuroligin-3 in male mice impact behavioral flexibility but not relational memory in a touchscreen test of visual transitive inference

scientific article published on 02 December 2019

N-Acetylcysteine improves mitochondrial function and ameliorates behavioral deficits in the R6/1 mouse model of Huntington's disease

scientific article

N-acetylcysteine modulates glutamatergic dysfunction and depressive behavior in Huntington's disease.

scientific article published on 14 May 2016

Nature, nurture and neurobiology: Gene-environment interactions in neuropsychiatric disorders.

scientific article published on 10 January 2013

Nature, nurture and neurology: gene-environment interactions in neurodegenerative disease. FEBS Anniversary Prize Lecture delivered on 27 June 2004 at the 29th FEBS Congress in Warsaw

scientific article

Neurocardiac dysregulation and neurogenic arrhythmias in a transgenic mouse model of Huntington's disease ⬇️

scientific article published on August 13, 2012

Neurodegenerative diseases

scientific article published on 01 January 2001

Neuroendocrine and neurotrophic signaling in Huntington's disease: Implications for pathogenic mechanisms and treatment strategies

scientific article

Neuroscience--Fifth IBRO World Congress. 11-15 July 1999, Jerusalem, Israel.

scientific article published in October 1999

Noninvasive strategies to optimise brain plasticity: from basic research to clinical perspectives.

scientific article published on 30 December 2013

Novel approaches to alcohol rehabilitation: Modification of stress-responsive brain regions through environmental enrichment.

scientific article published on 22 February 2018

Novel ethological endophenotypes in a transgenic mouse model of Huntington's disease

scientific article published on 18 April 2014

Novel therapeutic targets for Huntington's disease.

scientific article

Olfactory abnormalities in Huntington's disease: decreased plasticity in the primary olfactory cortex of R6/1 transgenic mice and reduced olfactory discrimination in patients

scientific article

PLC-beta1 knockout mice as a model of disrupted cortical development and plasticity: behavioral endophenotypes and dysregulation of RGS4 gene expression

scientific journal article

Paradoxical effects of exercise on hippocampal plasticity and cognition in mice with a heterozygous null mutation in the serotonin transporter gene

scientific article published on 15 July 2019

Paternal environmental enrichment transgenerationally alters affective behavioral and neuroendocrine phenotypes

scientific article

Phospholipase C beta 1 expression in the dorsolateral prefrontal cortex from patients with schizophrenia at different stages of illness.

scientific article published on 23 November 2010

Phospholipase C-beta1 expression correlates with neuronal differentiation and synaptic plasticity in rat somatosensory cortex.

scientific article

Plastic brains and gastrointestinal strains: The microbiota–gut–brain axis as a modulator of cellular plasticity and cognitive function (commentary on Darch et al., 2021)

scientific article published in 2021

Positive environmental modification of depressive phenotype and abnormal hypothalamic-pituitary-adrenal axis activity in female C57BL/6J mice during abstinence from chronic ethanol consumption

scientific article published on 23 July 2013

Reduced susceptibility to induced seizures in the Neuroligin-3(R451C) mouse model of autism.

scientific article published on 12 January 2015

Regulator of G-protein signalling 4 expression is not altered in the prefrontal cortex in schizophrenia

scientific article

Regulators of adult neurogenesis in the healthy and diseased brain

scientific article published on May 2007

Role of muscarinic receptors in the activity of N-desmethylclozapine: reversal of hyperactivity in the phospholipase C knockout mouse.

scientific article published in September 2008

Search strategy selection in the Morris water maze indicates allocentric map formation during learning that underpins spatial memory formation.

scientific article

Sex-specific behavioural effects of environmental enrichment in a transgenic mouse model of amyotrophic lateral sclerosis.

scientific article published on August 2008

Sex-specific disruptions in spatial memory and anhedonia in a "two hit" rat model correspond with alterations in hippocampal brain-derived neurotrophic factor expression and signaling

scientific article published on 16 May 2014

Sexually dimorphic dopaminergic dysfunction in a transgenic mouse model of Huntington's disease

scientific article published on 12 October 2014

Short-Term Environmental Enrichment is a Stronger Modulator of Brain Glial Cells and Cervical Lymph Node T Cell Subtypes than Exercise or Combined Exercise and Enrichment

scientific article published on 25 May 2020

Short-Term Environmental Stimulation Spatiotemporally Modulates Specific Serotonin Receptor Gene Expression and Behavioral Pharmacology in a Sexually Dimorphic Manner in Huntington's Disease Transgenic Mice

article

Short-term environmental enrichment, and not physical exercise, alleviate cognitive decline and anxiety from middle age onwards without affecting hippocampal gene expression

scientific article published on 01 October 2019

Short-term memory acquisition in female Huntington's disease mice is vulnerable to acute stress.

scientific article published on 31 July 2013

Simple sequence repeats: genetic modulators of brain function and behavior.

scientific article published on 10 June 2008

Social Isolation Alters Social and Mating Behavior in the R451C Neuroligin Mouse Model of Autism.

scientific article published on 31 January 2017

Society for neuroscience-33rd annual meeting.

scientific article published in January 2004

Stressing the Seminal Role of Paternal Experience in Transgenerational 'Epigenopathy' Affecting Offspring Health and Disease Susceptibility

scientific article published on 21 July 2018

Structural compartments within neurons: developmentally regulated organization of microfilament isoform mRNA and protein.

scientific article published in August 1998

Synaptopathic mechanisms of neurodegeneration and dementia: Insights from Huntington's disease.

scientific article

Synaptopathy, circuitopathy and the computational biology of Huntington's disease.

scientific article

TRPing up the genome: Tandem repeat polymorphisms as dynamic sources of genetic variability in health and disease.

scientific article published on October 2010

Tandem Repeats and Repeatomes: Delving Deeper into the 'Dark Matter' of Genomes.

scientific article

Tandem repeat polymorphisms: Mediators of genetic plasticity, modulators of biological diversity and dynamic sources of disease susceptibility

scientific article published on January 1, 2012

Tandem repeats mediating genetic plasticity in health and disease

scientific article published on 5 February 2018

The Role of Epigenetic Change in Autism Spectrum Disorders.

scientific article published on 26 May 2015

The effects of short-term and long-term environmental enrichment on locomotion, mood-like behavior, cognition and hippocampal gene expression

scientific article published on 17 April 2019

The influence of the HPG axis on stress response and depressive-like behaviour in a transgenic mouse model of Huntington's disease.

scientific article published on 20 September 2014

The latent stem cell population is retained in the hippocampus of transgenic Huntington's disease mice but not wild-type mice

scientific article

The relationship between cortisol and verbal memory in the early stages of Huntington's disease

scientific article published on 20 November 2012

Therapeutic Effects of Anthocyanins and Environmental Enrichment in R6/1 Huntington's Disease Mice

scientific article published on 12 August 2016

Thinking with your stomach? Gut feelings on microbiome modulation of brain structure and function (Commentary on Luczynski et al.).

scientific article published on 13 September 2016

Tissue-type plasminogen activator is an extracellular mediator of Purkinje cell damage and altered gait.

scientific article published on 9 August 2013

Touchscreen testing reveals clinically relevant cognitive abnormalities in a mouse model of schizophrenia lacking metabotropic glutamate receptor 5

scientific article published in Scientific Reports

Towards a therapy for Huntington's disease (Commentary on Giampà et al.).

scientific article published in March 2009

Towards environmental construct validity in animal models of CNS disorders: optimizing translation of preclinical studies.

scientific article published on August 2013

Toxoplasmosis: A pathway to neuropsychiatric disorders

scientific article published on 23 November 2018

Transcriptional profiles for distinct aggregation states of mutant Huntingtin exon 1 protein unmask new Huntington's disease pathways

scientific article

Transgenerational epigenetic impacts of parental infection on offspring health and disease susceptibility

scientific article published in 2022

Transgenerational epigenetic influences of paternal environmental exposures on brain function and predisposition to psychiatric disorders

scientific article published on 8 March 2018

Transgenerational paternal transmission of acquired traits: Stress-induced modification of the sperm regulatory transcriptome and offspring phenotypes

scientific article published on 8 March 2017

Transgenic Mouse Models as Tools for Understanding How Increased Cognitive and Physical Stimulation Can Improve Cognition in Alzheimer's Disease

scientific article published on 12 December 2018

Translating preclinical environmental enrichment studies for the treatment of autism and other brain disorders: comment on Woo and Leon (2013).

scientific article

Translational Assays for Assessment of Cognition in Rodent Models of Alzheimer's Disease and Dementia.

scientific article published on 16 September 2016

Treatment of depressive-like behaviour in Huntington's disease mice by chronic sertraline and exercise.

scientific article

Trinucleotide-repeat expansion diseases

scientific article published on 01 August 1997

Trinucleotide-repeat expansions and neurodegenerative diseases

scientific article published on 01 October 1995

Vascular endothelial growth factor and brain-derived neurotrophic factor in quetiapine treated first-episode psychosis

scientific article published on 05 February 2014

What's wrong with my mouse cage? Methodological considerations for modeling lifestyle factors and gene-environment interactions in mice

scientific article published on 13 August 2015

Wheel running and environmental enrichment differentially modify exon-specific BDNF expression in the hippocampus of wild-type and pre-motor symptomatic male and female Huntington's disease mice.

scientific article

Wheel running from a juvenile age delays onset of specific motor deficits but does not alter protein aggregate density in a mouse model of Huntington's disease

scientific article

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