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List of works by Thomas O Eichmann

A Class of Diacylglycerol Acyltransferase 1 Inhibitors Identified by a Combination of Phenotypic High-throughput Screening, Genomics, and Genetics

scientific article

A Monoallelic Two-Hit Mechanism in PLCD1 Explains the Genetic Pathogenesis of Hereditary Trichilemmal Cyst Formation

scientific article published on 11 May 2019

A novel mechanism for the biogenesis of outer membrane vesicles in Gram-negative bacteria

scientific article

A versatile ultra-high performance LC-MS method for lipid profiling

scientific article published on 29 January 2014

ABHD5 Stimulates PNPLA1-mediated Omega-O-Acylceramide Biosynthesis Essential for a Functional Skin Permeability Barrier

scientific article published on 25 October 2018

ATGL and CGI-58 are lipid droplet proteins of the hepatic stellate cell line HSC-T6

scientific article

ATGL-mediated fat catabolism regulates cardiac mitochondrial function via PPAR-α and PGC-1.

scientific article published on 21 August 2011

Abnormal composition and function of high-density lipoproteins in atopic dermatitis patients

scientific article published on 30 October 2018

Adipose triglyceride lipase acts on neutrophil lipid droplets to regulate substrate availability for lipid mediator synthesis

scientific article

Adipose triglyceride lipase affects triacylglycerol metabolism at brain barriers

scientific article

Adipose triglyceride lipase plays a key role in the supply of the working muscle with fatty acids

scientific article

Autotaxin-LPA signaling contributes to obesity-induced insulin resistance in muscle and impairs mitochondrial metabolism

scientific article published on 02 August 2018

Control of Drosophila Growth and Survival by the Lipid Droplet-Associated Protein CG9186/Sturkopf

scientific article published on 01 March 2019

Corrigendum: Pharmacological inhibition of adipose triglyceride lipase corrects high-fat diet-induced insulin resistance and hepatosteatosis in mice.

scientific article published on 25 April 2017

Critical role of the peroxisomal protein PEX16 in white adipocyte development and lipid homeostasis

scientific article published on 22 December 2016

DAG tales: the multiple faces of diacylglycerol--stereochemistry, metabolism, and signaling

scientific article

Deletion of Monoglyceride Lipase in Astrocytes Attenuates Lipopolysaccharide-induced Neuroinflammation

scientific article

Development of small-molecule inhibitors targeting adipose triglyceride lipase

scientific article published on 6 October 2013

Disruption of Lipid Uptake in Astroglia Exacerbates Diet-Induced Obesity.

scientific article published on 14 July 2017

Epidermal overexpression of xenobiotic receptor PXR impairs the epidermal barrier and triggers Th2 immune response.

scientific article

FAT SIGNALS--lipases and lipolysis in lipid metabolism and signaling

scientific article published in March 2012

Fasting-induced G0/G1 switch gene 2 and FGF21 expression in the liver are under regulation of adipose tissue derived fatty acids

scientific article published on 27 February 2015

G0/G1 Switch Gene 2 Regulates Cardiac Lipolysis.

scientific article published on 8 September 2015

Growth retardation, impaired triacylglycerol catabolism, hepatic steatosis, and lethal skin barrier defect in mice lacking comparative gene identification-58 (CGI-58).

scientific article

Homocysteine regulates fatty acid and lipid metabolism in yeast.

scientific article published on 6 February 2018

Impact of Endothelial Lipase on Cholesterol Efflux Capacity of Serum and High-density Lipoprotein

scientific article published on 2 October 2017

Isolation of Outer Membrane Vesicles Including Their Quantitative and Qualitative Analyses

scientific article published on 01 January 2018

Lipid droplets induced by secreted phospholipase A2 and unsaturated fatty acids protect breast cancer cells from nutrient and lipotoxic stress

scientific article published on 8 December 2017

Lipidomic data on lipid droplet triglyceride remodelling associated with protection of breast cancer cells from lipotoxic stress.

scientific article published on 12 March 2018

Lipoprotein Lipase Maintains Microglial Innate Immunity in Obesity

scientific article published in September 2017

Loss of ABHD15 Impairs the Anti-lipolytic Action of Insulin by Altering PDE3B Stability and Contributes to Insulin Resistance.

scientific article

Low cardiac lipolysis reduces mitochondrial fission and prevents lipotoxic heart dysfunction in Perilipin 5 mutant mice

scientific article published on 01 February 2020

Lysosomal Acid Lipase Hydrolyzes Retinyl Ester and Affects Retinoid Turnover

scientific article published on 27 June 2016

Measurement of lipolysis

scientific article published on January 2014

Monoacylglycerol Lipases Act as Evolutionarily Conserved Regulators of Non-oxidative Ethanol Metabolism

scientific article published on 31 March 2016

Monoglyceride lipase deficiency affects hepatic cholesterol metabolism and lipid-dependent gut transit in ApoE-/- mice

scientific article

Monoglyceride lipase deficiency causes desensitization of intestinal cannabinoid receptor type 1 and increased colonic μ-opioid receptor sensitivity

scientific article published on 30 July 2015

Monoglyceride lipase deficiency modulates endocannabinoid signaling and improves plaque stability in ApoE-knockout mice

scientific article

Neutral lipid storage disease: genetic disorders caused by mutations in adipose triglyceride lipase/PNPLA2 or CGI-58/ABHD5.

scientific article published on 28 April 2009

PNPLA1 Deficiency in Mice and Humans Leads to a Defect in the Synthesis of Omega-O-Acylceramides.

scientific article published on 14 October 2016

Pharmacological inhibition of adipose triglyceride lipase corrects high-fat diet-induced insulin resistance and hepatosteatosis in mice

scientific article published on 22 March 2017

Pharmacological inhibition of serine palmitoyl transferase and sphingosine kinase-1/-2 inhibits Merkel Cell Carcinoma cell proliferation

scientific article published on 03 November 2018

Quality control requirements for the correct annotation of lipidomics data

scientific article published on 6 August 2021

Reduced incorporation of fatty acids into triacylglycerol in myotubes from obese individuals with type 2 diabetes

scientific article published on 31 January 2014

Secretory phospholipase A2 modified HDL rapidly and potently suppresses platelet activation

scientific article published on 14 August 2017

Skin Barrier Development Depends on CGI-58 Protein Expression during Late-Stage Keratinocyte Differentiation

scientific article

Studies on the substrate and stereo/regioselectivity of adipose triglyceride lipase, hormone-sensitive lipase, and diacylglycerol-O-acyltransferases

scientific article published on 12 October 2012

The phospholipase PNPLA7 functions as a lysophosphatidylcholine hydrolase and interacts with lipid droplets through its catalytic domain

scientific article published on 7 September 2017

Transcriptional programming of lipid and amino acid metabolism by the skeletal muscle circadian clock

scientific article published on 10 August 2018

α/β Hydrolase Domain-containing 6 (ABHD6) Degrades the Late Endosomal/Lysosomal Lipid Bis(monoacylglycero)phosphate

scientific article published on 21 October 2015

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