List of works - Christopher M Weghorst

'Cold SSCP': a simple, rapid and non-radioactive method for optimized single-strand conformation polymorphism analyses

scientific article

A K-ras oncogene increases resistance to sulindac-induced apoptosis in rat enterocytes.

scientific article published in December 1997

A black raspberry extract inhibits proliferation and regulates apoptosis in cervical cancer cells.

scientific article published on 09 August 2011

Absence of p16/MTS1 gene mutations in human prostate cancer

scientific article published on 01 December 1996

Allelic imbalance in oral lichen planus and assessment of its classification as a premalignant condition.

scientific article

Alterations in RD(INK4/ARF) -mediated en bloc regulation of the INK4-ARF locus in human squamous cell carcinoma of the head and neck.

scientific article

Analysis of TGF-beta type I receptor for mutations and polymorphisms in head and neck cancers.

scientific article published in August 2001

Anticarcinogenic effects of cadmium in B6C3F1 mouse liver and lung

scientific article published on 01 September 1991

Bioactive compounds or metabolites from black raspberries modulate T lymphocyte proliferation, myeloid cell differentiation and Jak/STAT signaling

scientific article

Chemoprevention of mouse lung and colon tumors by suberoylanilide hydroxamic acid and atorvastatin

scientific article

Chemoprevention of oral cancer by topical application of black raspberries on high at-risk mucosa.

scientific article published on 16 September 2014

Chronic Helicobacter pylori Infection Induces an Apoptosis-Resistant Phenotype Associated with Decreased Expression of p27kip1.

scientific article published in November 2000

Chronic Helicobacter pylori infection induces an apoptosis-resistant phenotype associated with decreased expression of p27(kip1)

scientific article

Comparative Encapsulation Efficiency of Lutein in Micelles Synthesized via Batch and High Throughput Methods

scientific article published on 23 October 2020

Comparative effects of phenobarbital, DDT, and lindane on mouse hepatocyte gap junctional intercellular communication.

scientific article published in March 1990

Comparison of the effects of acute and subacute treatment of phenobarbital in different strains of mice

scientific article published on 01 November 1989

Comparisons of the conformational stability of cyclin-dependent kinase (CDK) 4-interacting ankyrin repeat (AR) proteins.

scientific article published in May 2009

Comprehensive evaluation of caspase-14 in vulvar neoplasia: an opportunity for treatment with black raspberry extract.

scientific article published on 23 September 2014

Contributions of conserved TPLH tetrapeptides to the conformational stability of ankyrin repeat proteins.

scientific article

Deletion of macrophage migration inhibitory factor inhibits murine oral carcinogenesis: Potential role for chronic pro-inflammatory immune mediators.

scientific article published on 10 May 2016

Dose response of hepatic and renal DNA synthetic rates to continuous exposure of bromodeoxyuridine (BrdU) via slow-release pellets or osmotic minipumps in male B6C3F1 mice

scientific article published on 01 February 1991

Effect of phenobarbital on diethylnitrosamine and dimethylnitrosamine induced hepatocellular tumors in male B6C3F1 mice.

scientific article published on September 1988

Evidence that P12, a specific variant of P16(INK4A), plays a suppressive role in human pancreatic carcinogenesis.

scientific article published on 29 May 2013

Expression of Cell Cycle Proteins in 4-(Methylnitrosamino)-1-(3-Pyridyl)-1-Butanone-Induced Mouse Lung Tumors ⬇️

scientific article published on July 1, 1998

Expression of cytochrome P450 2A3 in rat esophagus: relevance to N-nitrosobenzylmethylamine

scientific article

Expression of the p16INK4A/Cdkn2a gene is prevalently downregulated in human pheochromocytoma tumor specimens

scientific article published on 01 January 2008

Frequent alterations of p16INK4a and p14ARF in oral proliferative verrucous leukoplakia.

scientific article published in November 2008

Frequent mutation of p16 in squamous cell carcinoma of the head and neck.

scientific article published in June 1998

Genetic alterations of RD(INK4/ARF) enhancer in human cancer cells

scientific article published on 12 October 2012

Histogenesis and the role of p53 and K-ras mutations in hepatocarcinogenesis by glyceryl trinitrate (nitroglycerin) in male F344 rats.

scientific article published on November 1996

IKKbeta specifically binds to P16 and phosphorylates Ser8 of P16.

scientific article

Identification and sequencing of the Syrian Golden hamster (Mesocricetus auratus) p16(INK4a) and p15(INK4b) cDNAs and their homozygous gene deletion in cheek pouch and pancreatic tumor cells.

scientific article

Identification of genetic alterations in the TGFbeta type II receptor gene promoter.

scientific article

Ineffectiveness of the presence of H-ras/p53 combination of mutations in squamous cell carcinoma cells to induce a conversion of a nontumorigenic to a tumorigenic phenotype

scientific article published on 01 October 1997

Lack of p53 and ras mutations in Helicobacter hepaticus-induced liver tumors in A/JCr mice.

scientific article published in January 1997

Lack of p53 point mutations in chemically induced mouse hepatoblastomas: an end-stage, highly malignant hepatocellular tumor

scientific article published on 01 August 1995

Lack of promoting effect of clonazepam on the development of N-nitrosodiethylamine-initiated hepatocellular tumors in mice is correlated with its inability to inhibit cell-to-cell communication in mouse hepatocytes.

scientific article

Low frequency of H-ras activation in naturally occurring hepatocellular tumors of C3H/HeNCr mice.

scientific article published on September 1993

Metabolic Regulation of Glycolysis and AMP Activated Protein Kinase Pathways during Black Raspberry-Mediated Oral Cancer Chemoprevention

scientific article published on 11 July 2019

Mutation and downregulation of the transforming growth factor beta type II receptor gene in primary squamous cell carcinomas of the head and neck

scientific article published on 01 November 1997

Mutation in the p53 tumor suppressor gene in rat esophageal papillomas induced by N-nitrosomethylbenzylamine.

scientific article

Mutation of the p53 tumor suppressor gene in spontaneously occurring osteosarcomas of the dog

scientific article published on 01 January 1998

Progressive atypia in spontaneous and N-nitrosodiethylamine-induced hepatocellular adenomas of C3H/HeNCr mice.

scientific article published on September 1992

RET mutation screening in MEN2 patients and discovery of a novel mutation in a sporadic medullary thyroid carcinoma

scientific article published on 01 April 1996

Somatic acquisition and signaling of TGFBR1*6A in cancer

scientific article

Storage conditions modulate the metabolomic profile of a black raspberry nectar with minimal impact on bioactivity

scientific article published on 01 September 2018

Suppression of Proinflammatory and Prosurvival Biomarkers in Oral Cancer Patients Consuming a Black Raspberry Phytochemical-Rich Troche

scientific article published on 23 December 2015

The choice of reference gene affects statistical efficiency in quantitative PCR data analysis

scientific article

The p16/Cdkn2a/Ink4a gene is frequently deleted in nitrosourea-induced rat glial tumors.

scientific article

The study of pH-dependent stability shows that the TPLH-mediated hydrogen-bonding network is important for the conformation and stability of human gankyrin.

scientific article published on 8 July 2013

p16 Mutation Frequency and Clinical Correlation in Head and Neck Cancer

scientific article published on 01 March 1999

List of works by Christopher M Weghorst

'Cold SSCP': a simple, rapid and non-radioactive method for optimized single-strand conformation polymorphism analyses

A K-ras oncogene increases resistance to sulindac-induced apoptosis in rat enterocytes.

A black raspberry extract inhibits proliferation and regulates apoptosis in cervical cancer cells.

Absence of p16/MTS1 gene mutations in human prostate cancer

Allelic imbalance in oral lichen planus and assessment of its classification as a premalignant condition.

Alterations in RD(INK4/ARF) -mediated en bloc regulation of the INK4-ARF locus in human squamous cell carcinoma of the head and neck.

Analysis of TGF-beta type I receptor for mutations and polymorphisms in head and neck cancers.

Anticarcinogenic effects of cadmium in B6C3F1 mouse liver and lung

Bioactive compounds or metabolites from black raspberries modulate T lymphocyte proliferation, myeloid cell differentiation and Jak/STAT signaling

Chemoprevention of mouse lung and colon tumors by suberoylanilide hydroxamic acid and atorvastatin

Chemoprevention of oral cancer by topical application of black raspberries on high at-risk mucosa.

Chronic Helicobacter pylori Infection Induces an Apoptosis-Resistant Phenotype Associated with Decreased Expression of p27kip1.

Chronic Helicobacter pylori infection induces an apoptosis-resistant phenotype associated with decreased expression of p27(kip1)

Comparative Encapsulation Efficiency of Lutein in Micelles Synthesized via Batch and High Throughput Methods

Comparative effects of phenobarbital, DDT, and lindane on mouse hepatocyte gap junctional intercellular communication.

Comparison of the effects of acute and subacute treatment of phenobarbital in different strains of mice

Comparisons of the conformational stability of cyclin-dependent kinase (CDK) 4-interacting ankyrin repeat (AR) proteins.

Comprehensive evaluation of caspase-14 in vulvar neoplasia: an opportunity for treatment with black raspberry extract.

Contributions of conserved TPLH tetrapeptides to the conformational stability of ankyrin repeat proteins.

Deletion of macrophage migration inhibitory factor inhibits murine oral carcinogenesis: Potential role for chronic pro-inflammatory immune mediators.

Dose response of hepatic and renal DNA synthetic rates to continuous exposure of bromodeoxyuridine (BrdU) via slow-release pellets or osmotic minipumps in male B6C3F1 mice

Effect of phenobarbital on diethylnitrosamine and dimethylnitrosamine induced hepatocellular tumors in male B6C3F1 mice.

Evidence that P12, a specific variant of P16(INK4A), plays a suppressive role in human pancreatic carcinogenesis.

Expression of Cell Cycle Proteins in 4-(Methylnitrosamino)-1-(3-Pyridyl)-1-Butanone-Induced Mouse Lung Tumors ⬇️

Expression of cytochrome P450 2A3 in rat esophagus: relevance to N-nitrosobenzylmethylamine

Expression of the p16INK4A/Cdkn2a gene is prevalently downregulated in human pheochromocytoma tumor specimens

Frequent alterations of p16INK4a and p14ARF in oral proliferative verrucous leukoplakia.

Frequent mutation of p16 in squamous cell carcinoma of the head and neck.

Genetic alterations of RD(INK4/ARF) enhancer in human cancer cells

Histogenesis and the role of p53 and K-ras mutations in hepatocarcinogenesis by glyceryl trinitrate (nitroglycerin) in male F344 rats.

IKKbeta specifically binds to P16 and phosphorylates Ser8 of P16.

Identification and sequencing of the Syrian Golden hamster (Mesocricetus auratus) p16(INK4a) and p15(INK4b) cDNAs and their homozygous gene deletion in cheek pouch and pancreatic tumor cells.

Identification of genetic alterations in the TGFbeta type II receptor gene promoter.

Ineffectiveness of the presence of H-ras/p53 combination of mutations in squamous cell carcinoma cells to induce a conversion of a nontumorigenic to a tumorigenic phenotype

Lack of p53 and ras mutations in Helicobacter hepaticus-induced liver tumors in A/JCr mice.

Lack of p53 point mutations in chemically induced mouse hepatoblastomas: an end-stage, highly malignant hepatocellular tumor

Lack of promoting effect of clonazepam on the development of N-nitrosodiethylamine-initiated hepatocellular tumors in mice is correlated with its inability to inhibit cell-to-cell communication in mouse hepatocytes.

Low frequency of H-ras activation in naturally occurring hepatocellular tumors of C3H/HeNCr mice.

Metabolic Regulation of Glycolysis and AMP Activated Protein Kinase Pathways during Black Raspberry-Mediated Oral Cancer Chemoprevention

Mutation and downregulation of the transforming growth factor beta type II receptor gene in primary squamous cell carcinomas of the head and neck

Mutation in the p53 tumor suppressor gene in rat esophageal papillomas induced by N-nitrosomethylbenzylamine.

Mutation of the p53 tumor suppressor gene in spontaneously occurring osteosarcomas of the dog

Progressive atypia in spontaneous and N-nitrosodiethylamine-induced hepatocellular adenomas of C3H/HeNCr mice.

RET mutation screening in MEN2 patients and discovery of a novel mutation in a sporadic medullary thyroid carcinoma

Somatic acquisition and signaling of TGFBR1*6A in cancer

Storage conditions modulate the metabolomic profile of a black raspberry nectar with minimal impact on bioactivity

Suppression of Proinflammatory and Prosurvival Biomarkers in Oral Cancer Patients Consuming a Black Raspberry Phytochemical-Rich Troche

The choice of reference gene affects statistical efficiency in quantitative PCR data analysis

The p16/Cdkn2a/Ink4a gene is frequently deleted in nitrosourea-induced rat glial tumors.

The study of pH-dependent stability shows that the TPLH-mediated hydrogen-bonding network is important for the conformation and stability of human gankyrin.

p16 Mutation Frequency and Clinical Correlation in Head and Neck Cancer