List of works - Gregory D Funk

A brainstem peptide system activated at birth protects postnatal breathing

scientific article published on 02 December 2020

A method for activating neurons using endogenous synaptic waveforms

scientific article published on 01 March 2000

ATP in central respiratory control: a three-part signaling system.

scientific article published on December 2008

ATP sensitivity of preBötzinger complex neurones in neonatal rat in vitro: mechanism underlying a P2 receptor-mediated increase in inspiratory frequency.

scientific article published on 3 January 2008

Ampakine CX717 protects against fentanyl-induced respiratory depression and lethal apnea in rats.

scientific article

Anxiety-related mechanisms of respiratory dysfunction in a mouse model of Rett syndrome.

scientific article

Breathing matters

scientific article published on 01 June 2018

Changes in ventilation and breathing pattern produced by changing body temperature and inspired CO2 concentration in turtles

scientific article published on 01 January 1987

CrossTalk proposal: a central hypoxia sensor contributes to the excitatory hypoxic ventilatory response

scientific article published on 27 June 2018

Dbx1 precursor cells are a source of inspiratory XII premotoneurons.

scientific article published on 19 December 2015

Development of thyrotropin-releasing hormone and norepinephrine potentiation of inspiratory-related hypoglossal motoneuron discharge in neonatal and juvenile mice in vitro

scientific article published on 01 November 1994

Developmental downregulation of P2X3 receptors in motoneurons of the compact formation of the nucleus ambiguus.

scientific article

Developmental modulation of glutamatergic inspiratory drive to hypoglossal motoneurons.

scientific article published in November 1997

Developmental modulation of mouse hypoglossal nerve inspiratory output in vitro by noradrenergic receptor agonists.

scientific article published in September 1998

Differential expression of Group I metabotropic glutamate receptors in motoneurons at low and high risk for degeneration in ALS.

scientific article published in July 2001

Differential expression of group I metabotropic glutamate receptors in human motoneurons at low and high risk of degeneration in amyotrophic lateral sclerosis

scientific article published on 18 September 2006

Differential expression of voltage-activated calcium channels in III and XII motoneurones during development in the rat.

scientific article

Effects of muscarinic acetylcholine receptor activation on membrane currents and intracellular messengers in medium spiny neurones of the rat striatum.

scientific article published in September 2004

Excitatory Modulation of the preBötzinger Complex Inspiratory Rhythm Generating Network by Endogenous Hydrogen Sulfide.

scientific article

Fluorescent tagging of rhythmically active respiratory neurons within the pre-Bötzinger complex of rat medullary slice preparations.

scientific article

Fuelling the Fire of Life: A tribute to Professor W.K. Milsom.

scientific article published on 5 March 2015

Functional Oxygen Sensitivity of Astrocytes.

scientific article published in July 2015

Functional respiratory rhythm generating networks in neonatal mice lacking NMDAR1 gene.

scientific article published in September 1997

Generation of eupnea and sighs by a spatiochemically organized inspiratory network

scientific article published on 01 March 2008

Generation of respiratory rhythm and pattern in mammals: insights from developmental studies.

scientific article published on December 1995

Glia contribute to the purinergic modulation of inspiratory rhythm-generating networks.

scientific article published in March 2010

Glial TLR4 signaling does not contribute to opioid-induced depression of respiration

scientific article

High frequency oscillations in respiratory networks: functionally significant or phenomenological?

scientific article

High sensitivity to neuromodulator-activated signaling pathways at physiological [K+] of confocally imaged respiratory center neurons in on-line-calibrated newborn rat brainstem slices.

scientific article published in November 2006

I think I(CAN): modulation of TRPM4 channels may contribute not only to the emergence of rhythm, but robust output and metabolic sensitivity of the preBötzinger Complex inspiratory network.

scientific article published in April 2013

Laser ablation of Dbx1 neurons in the pre-Bötzinger complex stops inspiratory rhythm and impairs output in neonatal mice

scientific article

Losing sleep over the caffeination of prematurity

scientific article

Modulation of hypoglossal motoneuron excitability by NK1 receptor activation in neonatal mice in vitro

scientific article

Modulation of phrenic motoneuron excitability by ATP: consequences for respiratory-related output in vitro.

scientific article published in May 2002

Neuroglia and their roles in central respiratory control; an overview.

scientific article

Noradrenergic modulation of XII motoneuron inspiratory activity does not involve alpha2-receptor inhibition of the Ih current or presynaptic glutamate release.

scientific article published on 3 December 2004

On the existence of a central respiratory oxygen sensor

scientific article

Opiate-induced suppression of rat hypoglossal motoneuron activity and its reversal by ampakine therapy

scientific article published in 2010

P2 receptors modulate respiratory rhythm but do not contribute to central CO2 sensitivity in vitro.

scientific article published in August 2004

P2Y1 receptor modulation of the pre-Bötzinger complex inspiratory rhythm generating network in vitro.

scientific article

P2Y1 receptor-mediated potentiation of inspiratory motor output in neonatal rat in vitro.

scientific article

Perinatal development of respiratory motoneurons.

scientific article

Phylogenetically persistent purinergic modulation of central pattern generators for breathing in lamprey and mammals

scientific article

Postnatal development of persistent inward currents in rat XII motoneurons and their modulation by serotonin, muscarine and noradrenaline

scientific article published on 22 May 2019

Prenatal nicotine exposure increases apnoea and reduces nicotinic potentiation of hypoglossal inspiratory output in mice

scientific article

Preparing for the first breath: prenatal maturation of respiratory neural control.

scientific article

Purinergic modulation of preBötzinger complex inspiratory rhythm in rodents: the interaction between ATP and adenosine ⬇️

scientific article published on July 25, 2011

Rebuttal from Gregory D. Funk and Alexander V. Gourine.

scientific article published on 26 June 2018

Receptor subtype-specific modulation by dopamine of glutamatergic responses in striatal medium spiny neurons.

scientific article

Release of ATP by pre-Bötzinger complex astrocytes contributes to the hypoxic ventilatory response via a Ca2+ -dependent P2Y1 receptor mechanism.

scientific article

Rhythmical oral-motor activity recorded in an in vitro brainstem preparation.

scientific article

Special issue: 'Neural Control of Breathing'.

scientific article published in July 2002

State-dependent modulation of breathing in urethane-anesthetized rats.

scientific article

Substance P modulation of hypoglossal motoneuron excitability during development: changing balance between conductances

scientific article

Synaptic control of motoneuron excitability in rodents: from months to milliseconds.

scientific article

The rhythmic, transverse medullary slice preparation in respiratory neurobiology: contributions and caveats.

scientific article published on 26 January 2013

The role of P2Y1 receptor signaling in central respiratory control

scientific article published on 14 October 2015

The ‘connexin’ between astrocytes, ATP and central respiratory chemoreception ⬇️

scientific article published on November 15, 2010

Tripartite purinergic modulation of central respiratory networks during perinatal development: the influence of ATP, ectonucleotidases, and ATP metabolites

scientific article published in November 2009

List of works by Gregory D Funk

A brainstem peptide system activated at birth protects postnatal breathing

A method for activating neurons using endogenous synaptic waveforms

ATP in central respiratory control: a three-part signaling system.

ATP sensitivity of preBötzinger complex neurones in neonatal rat in vitro: mechanism underlying a P2 receptor-mediated increase in inspiratory frequency.

Ampakine CX717 protects against fentanyl-induced respiratory depression and lethal apnea in rats.

Anxiety-related mechanisms of respiratory dysfunction in a mouse model of Rett syndrome.

Breathing matters

Changes in ventilation and breathing pattern produced by changing body temperature and inspired CO2 concentration in turtles

CrossTalk proposal: a central hypoxia sensor contributes to the excitatory hypoxic ventilatory response

Dbx1 precursor cells are a source of inspiratory XII premotoneurons.

Development of thyrotropin-releasing hormone and norepinephrine potentiation of inspiratory-related hypoglossal motoneuron discharge in neonatal and juvenile mice in vitro

Developmental downregulation of P2X3 receptors in motoneurons of the compact formation of the nucleus ambiguus.

Developmental modulation of glutamatergic inspiratory drive to hypoglossal motoneurons.

Developmental modulation of mouse hypoglossal nerve inspiratory output in vitro by noradrenergic receptor agonists.

Differential expression of Group I metabotropic glutamate receptors in motoneurons at low and high risk for degeneration in ALS.

Differential expression of group I metabotropic glutamate receptors in human motoneurons at low and high risk of degeneration in amyotrophic lateral sclerosis

Differential expression of voltage-activated calcium channels in III and XII motoneurones during development in the rat.

Effects of muscarinic acetylcholine receptor activation on membrane currents and intracellular messengers in medium spiny neurones of the rat striatum.

Excitatory Modulation of the preBötzinger Complex Inspiratory Rhythm Generating Network by Endogenous Hydrogen Sulfide.

Fluorescent tagging of rhythmically active respiratory neurons within the pre-Bötzinger complex of rat medullary slice preparations.

Fuelling the Fire of Life: A tribute to Professor W.K. Milsom.

Functional Oxygen Sensitivity of Astrocytes.

Functional respiratory rhythm generating networks in neonatal mice lacking NMDAR1 gene.

Generation of eupnea and sighs by a spatiochemically organized inspiratory network

Generation of respiratory rhythm and pattern in mammals: insights from developmental studies.

Glia contribute to the purinergic modulation of inspiratory rhythm-generating networks.

Glial TLR4 signaling does not contribute to opioid-induced depression of respiration

High frequency oscillations in respiratory networks: functionally significant or phenomenological?

High sensitivity to neuromodulator-activated signaling pathways at physiological [K+] of confocally imaged respiratory center neurons in on-line-calibrated newborn rat brainstem slices.

I think I(CAN): modulation of TRPM4 channels may contribute not only to the emergence of rhythm, but robust output and metabolic sensitivity of the preBötzinger Complex inspiratory network.

Laser ablation of Dbx1 neurons in the pre-Bötzinger complex stops inspiratory rhythm and impairs output in neonatal mice

Losing sleep over the caffeination of prematurity

Modulation of hypoglossal motoneuron excitability by NK1 receptor activation in neonatal mice in vitro

Modulation of phrenic motoneuron excitability by ATP: consequences for respiratory-related output in vitro.

Neuroglia and their roles in central respiratory control; an overview.

Noradrenergic modulation of XII motoneuron inspiratory activity does not involve alpha2-receptor inhibition of the Ih current or presynaptic glutamate release.

On the existence of a central respiratory oxygen sensor

Opiate-induced suppression of rat hypoglossal motoneuron activity and its reversal by ampakine therapy

P2 receptors modulate respiratory rhythm but do not contribute to central CO2 sensitivity in vitro.

P2Y1 receptor modulation of the pre-Bötzinger complex inspiratory rhythm generating network in vitro.

P2Y1 receptor-mediated potentiation of inspiratory motor output in neonatal rat in vitro.

Perinatal development of respiratory motoneurons.

Phylogenetically persistent purinergic modulation of central pattern generators for breathing in lamprey and mammals

Postnatal development of persistent inward currents in rat XII motoneurons and their modulation by serotonin, muscarine and noradrenaline

Prenatal nicotine exposure increases apnoea and reduces nicotinic potentiation of hypoglossal inspiratory output in mice

Preparing for the first breath: prenatal maturation of respiratory neural control.

Purinergic modulation of preBötzinger complex inspiratory rhythm in rodents: the interaction between ATP and adenosine ⬇️

Rebuttal from Gregory D. Funk and Alexander V. Gourine.

Receptor subtype-specific modulation by dopamine of glutamatergic responses in striatal medium spiny neurons.

Release of ATP by pre-Bötzinger complex astrocytes contributes to the hypoxic ventilatory response via a Ca2+ -dependent P2Y1 receptor mechanism.

Rhythmical oral-motor activity recorded in an in vitro brainstem preparation.

Special issue: 'Neural Control of Breathing'.

State-dependent modulation of breathing in urethane-anesthetized rats.

Substance P modulation of hypoglossal motoneuron excitability during development: changing balance between conductances

Synaptic control of motoneuron excitability in rodents: from months to milliseconds.

The rhythmic, transverse medullary slice preparation in respiratory neurobiology: contributions and caveats.

The role of P2Y1 receptor signaling in central respiratory control

The ‘connexin’ between astrocytes, ATP and central respiratory chemoreception ⬇️

Tripartite purinergic modulation of central respiratory networks during perinatal development: the influence of ATP, ectonucleotidases, and ATP metabolites