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List of works by Richard Mailman

"Full" dopamine D1 agonists in human caudate: biochemical properties and therapeutic implications

scientific article published on 01 May 1995

8,9-dihydroxy-1,2,3,11b-tetrahydrochromeno[4,3,2,-de]isoquinoline (dinoxyline), a high affinity and potent agonist at all dopamine receptor isoforms.

scientific article

A novel role of CDX1 in embryonic epicardial development

scientific article

Amygdaloid D1 receptors are not linked to stimulation of adenylate cyclase.

scientific article published on December 2003

An evaluation of the selectivity of fenmetozole (DH-524) reversal of ethanol-induced changes in central nervous system function ⬇️

scientific article published on January 1, 1980

Apolipoprotein E genotypes and the risk of Parkinson disease

scientific article

Application of validated QSAR models of D1 dopaminergic antagonists for database mining

scientific article published in November 2005

Aripiprazole has functionally selective actions at dopamine D2 receptor-mediated signaling pathways.

scientific article

Aripiprazole, a novel atypical antipsychotic drug with a unique and robust pharmacology.

scientific article

Ascorbic acid decreases [(3)H]dopamine binding in striatum without inhibiting dopamine-sensitive adenylate cyclase

scientific article published on 01 January 1984

Asymmetrical lateral ventricular enlargement in Parkinson's disease.

scientific article

Attenuation of the effects of punishment by ethanol: comparisons with chlordiazepoxide.

scientific article published in January 1980

Behavioral and biochemical studies of the scopolamine-induced reversal of neuroleptic activity ⬇️

scientific article published on January 1, 1981

Behavioral and prolactin responses to 5-hydroxytrytophan in rats treated during development with 5,7-dihydroxytryptamine ⬇️

scientific article published on October 27, 1978

Behavioural assessment of mice lacking D1A dopamine receptors

scientific journal article

Blockade of only spinal alpha 1 adrenoceptors is insufficient to attenuate DDT-induced alterations in motor function

scientific article published on 01 October 1989

Blunted brain metabolic response to ketamine in mice lacking D(1A) dopamine receptors

scientific journal article

Calcitonin depresses amphetamine-induced locomotor activity.

scientific article published in June 1983

Cerebellar cGMP varies with motor function and respiratory gas exchange

scientific article published on 01 November 1978

Conformational analysis of D1 dopamine receptor agonists: pharmacophore assessment and receptor mapping

scientific article published on 01 January 1996

Cresylbenzodioxaphosphorin oxide pretreatment alters soman-induced toxicity and inhibition of tissue cholinesterase activity of the rat.

scientific article published on July 1989

D1 and functionally selective dopamine agonists as neuroprotective agents in Parkinson's disease.

scientific article published on June 2006

Developmental regulation of the dopamine D1 receptor in human caudate and putamen.

scientific article published in November 1999

Differential effects of clozapine and haloperidol on ketamine-induced brain metabolic activation.

scientific article published in November 1998

Dihydrexidine, a full dopamine D1 agonist, reduces MPTP-ioduced parkinsonism in monkeys ⬇️

scientific article published on July 9, 1991

Dopamine D1 receptor signaling: does GαQ-phospholipase C actually play a role?

scientific article

Dopamine D1 receptors: efficacy of full (dihydrexidine) vs. partial (SKF38393) agonists in primates vs. rodents

scientific article published on 01 September 1993

Dopamine receptor pharmacology

scientific article published on 01 January 2007

Effect of 5,7-dihydroxytryptamine on serotonergic control of prolactin secretion and behavior in rats

scientific article published on 01 January 1981

Effects of dopaminergic agonists and antagonists on cerebellar guanosine-3′, 5′-monophosphate (cGMP) ⬇️

scientific article published on August 7, 1978

Effects of trimethyltin on dopaminergic and serotonergic function in the central nervous system ⬇️

scientific article published on September 15, 1984

Evaluation of the effects of nerve growth factor and anti-nerve growth factor on the development of central catecholamine-containing neurons ⬇️

scientific article published on April 14, 1978

Functional Selectivity and Classical Concepts of Quantitative Pharmacology

scientific article

Functional selectivity of dopamine receptor agonists. I. Selective activation of postsynaptic dopamine D2 receptors linked to adenylate cyclase

scientific article (publication date: June 2002)

Functional selectivity of dopamine receptor agonists. II. Actions of dihydrexidine in D2L receptor-transfected MN9D cells and pituitary lactotrophs

scientific article (publication date: June 2002)

Further Definition of the D1 Dopamine Receptor Pharmacophore: Synthesis of trans-6,6a,7,8,9,13b-Hexahydro-5H-benzo[d]naphth[2,1-b]azepines as Rigid Analogues of β-Phenyldopamine ⬇️

scientific article published on July 4, 1997

Guanine nucleotide binding proteins and the regulation of cyclic AMP synthesis in NS20Y neuroblastoma cells: role of D1 dopamine and muscarinic receptors ⬇️

scientific article published on August 9, 1991

Heterotypic sprouting of serotonergic forebrain fibers in the brindled mottled mutant mouse

scientific journal article

Hexahydrobenzo[a]phenanthridines: novel dopamine D3 receptor ligands

scientific article published on 01 August 1993

Higher iron in the red nucleus marks Parkinson's dyskinesia.

scientific article published on 21 November 2012

Importance of the Locus coeruleus and involvement of alpha-adrenergic receptors in the post-decapitation reflex in the rat.

scientific article

In vivo metabolism and excretion of propoxur and malathion in the rat: effect of lead treatment.

scientific article published in June 1981

Increased R2* in the Caudate Nucleus of Asymptomatic Welders

scientific article published on 14 January 2016

Induction of hepatic mixed function oxidases by the insecticide, mirex

scientific article published on 01 December 1972

Interhemispheric modulation of dopamine receptor interactions in unilateral 6-OHDA rodent model

scientific article published on 01 December 1995

Lateralized basal ganglia vulnerability to pesticide exposure in asymptomatic agricultural workers

scientific article published on 19 June 2017

Locomotor inhibition, yawning and vacuous chewing induced by a novel dopamine D2 post-synaptic receptor agonist

scientific article published on 01 March 1997

Long-term effects of early social isolation in Macaca mulatta: changes in dopamine receptor function following apomorphine challenge.

scientific article published on April 1990

Low LDL cholesterol and increased risk of Parkinson's disease: prospective results from Honolulu-Asia Aging Study

scientific article

Low affinity binding of the classical D1 antagonist SCH23390 in rodent brain: potential interaction with A2A and D2-like receptors

scientific article

Lower low-density lipoprotein cholesterol levels are associated with Parkinson's disease

scientific article published in February 2007

Metabolism of thioridazine by microsomal monooxygenases: relative roles of P450 and flavin-containing monooxygenase.

scientific article published in April 1995

Microstructural changes in the substantia nigra of asymptomatic agricultural workers

scientific article

Morphological and Cytochemical Characterization of Neuroepithelial Bodies in Fetal Rabbit Lung I. Studies of Isolated Neuroepithelial Bodies ⬇️

scientific article published on November 1, 1982

Multiplicity of hepatic cytochrome P-450 in intact microsomes: effect of 3-methylcholanthrene induction

scientific article published on 01 January 1977

Multiplicity of hepatic cytochrome P-450 in intact microsomes: effect of phenobarbital induction

scientific article published on 01 January 1977

Noradrenergic hyperinnervation reduces the density of β-adrenergic receptors in rat cerebellum ⬇️

scientific article published on April 20, 1979

Novel Dopamine Therapeutics for Cognitive Deficits in Schizophrenia.

scientific article published on 18 January 2016

Postmortem stability of dopamine D1 receptor mRNA and D1 receptors.

scientific article published in June 1993

Projection of the prevalence of Parkinson's disease in the coming decades: Revisited

scientific article published on 07 June 2017

Pyrethroid insecticides and radioligand displacement from the GABA receptor chloride ionophore complex.

scientific article published in February 1987

Quantification of R-(+)-7-chloro-8-hydroxy-1-phenyl-2,3,4,5-tetrahydro-1H-3-methyl-3- benzazepine in brain and blood by use of reversed-phase high-performance liquid chromatography with electrochemical detection

scientific article published on 01 August 1985

RLH-033, a novel, potent and selective ligand for the sigma 1 recognition site

scientific article published on 01 December 1994

Rearing conditions alter social reactivity and D1 dopamine receptors in high- and low-aggressive mice

scientific article published on 01 August 1995

Reply: Plasma cholesterol and Parkinson's disease: Is the puzzle only apparent?

scientific article

Responses of dopaminergic and serotonergic systems to triethyllead intoxication.

scientific article

S(-)DP-5,6-ADTN as an in vivo dopamine receptor ligand: relation between displacement by dopamine agonists and their pharmacological effects.

scientific article published in April 1986

SCH-23390: a selective D1 dopamine antagonist with potent D2 behavioral actions

scientific article published on 01 May 1984

SKF-83959 is not a highly-biased functionally selective D1 dopamine receptor ligand with activity at phospholipase C

scientific article

Serotonergic basis of antipsychotic drug effects in schizophrenia.

scientific article published on December 1998

Serum cholesterol and nigrostriatal R2* values in Parkinson's disease

scientific article

Serum cholesterol and the progression of Parkinson's disease: results from DATATOP.

scientific article

Serum effects confound the neuroleptic radioreceptor assay

scientific article published on 01 March 1984

Simultaneous determination of thioridazine and its S-oxidized and N-demethylated metabolites using high-performance liquid-chromatography on radially compressed silica

scientific article published on 01 September 1982

Simultaneous quantification of dopamine, 5-hydroxytryptamine and four metabolically related compounds by means of reversed-phase high-performance liquid chromatography with electrochemical detection

scientific article published on 01 October 1981

Spare receptors and intrinsic activity: studies with D1 dopamine receptor agonists.

scientific article published in October 1995

Statins may facilitate Parkinson's disease: Insight gained from a large, national claims database

scientific article

Statins, plasma cholesterol, and risk of Parkinson's disease: a prospective study

scientific article

Striatal volume changes in the rat following long-term administration of typical and atypical antipsychotic drugs.

scientific article

Substituted naphthofurans as hallucinogenic phenethylamine-ergoline hybrid molecules with unexpected muscarinic antagonist activity.

scientific article

Synthesis and SAR exploration of dinapsoline analogues.

scientific article

Synthesis and dopaminergic properties of benzo-fused analogues of quinpirole and quinelorane.

scientific article published in March 1999

T1 Relaxation Rate (R1) Indicates Nonlinear Mn Accumulation in Brain Tissue of Welders With Low-Level Exposure

scientific article

The cytochrome P-450 substrate optical difference spectra of pesticides with mouse hepatic microsomes

scientific article published on 01 September 1972

The effect of 2-(o-cresyl)-4H-1:3:2-benzodioxaphosphorin-2-oxide on tissue cholinesterase and carboxylesterase activities of the rat

scientific article published on 01 October 1989

The effect of drugs which alter GABA-ergic function on cerebellar guanosine-3′, 5′-monophosphate content ⬇️

scientific article published on August 14, 1978

The effects of lead administration during development on lithium-induced polydipsia and dopaminergic function.

scientific article published in April 1984

The occurrence of multiple forms of cytochrome P-450 in hepatic microsomes from untreated rats and mice

scientific article published on 01 March 1975

The perplexing paradox of paraquat: the case for host-based susceptibility and postulated neurodegenerative effects

scientific article

Third generation antipsychotic drugs: partial agonism or receptor functional selectivity?

scientific article

Transcriptional repression by the BRG1-SWI/SNF complex affects the pluripotency of human embryonic stem cells.

scientific article

Triadimefon and triadimenol: effects on monoamine uptake and release.

scientific article

Triadimefon, a triazole fungicide, induces stereotyped behavior and alters monoamine metabolism in rats.

scientific article published on March 1990

Variability in soman toxicity in the rat: correlation with biochemical and behavioral measures

scientific article published on 01 August 1989

[3H]SCH23390 has the characteristics of a dopamine receptor ligand in the rat central nervous system.

scientific article published in October 1984

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