List of works - Mauro W Costa

A novel conditional mouse model for Nkx2-5 reveals transcriptional regulation of cardiac ion channels.

scientific article published on 17 February 2016

A tyrosine-rich domain within homeodomain transcription factor Nkx2-5 is an essential element in the early cardiac transcriptional regulatory machinery

scientific journal article

CARFMAP: A Curated Pathway Map of Cardiac Fibroblasts

scientific article published on 16 December 2015

Cardiac T-box factor Tbx20 directly interacts with Nkx2-5, GATA4, and GATA5 in regulation of gene expression in the developing heart

scientific journal article

Cardiogenic genes expressed in cardiac fibroblasts contribute to heart development and repair

scientific article

Complex SUMO-1 regulation of cardiac transcription factor Nkx2-5

scientific article

Conformational stability and DNA binding specificity of the cardiac T-box transcription factor Tbx20.

scientific article published on 3 May 2009

Deletion of Nkx2-5 in trabecular myocardium reveals the developmental origins of pathological heterogeneity associated with ventricular non-compaction cardiomyopathy

scientific article published on 06 July 2018

DuOx2 Promoter Regulation by Hormones, Transcriptional Factors and the Coactivator TAZ.

scientific article

Effect of oxygen on cardiac differentiation in mouse iPS cells: role of hypoxia inducible factor-1 and Wnt/beta-catenin signaling

scientific article

Enhancing the efficacy of glycolytic blockade in cancer cells via RAD51 inhibition

scientific article published on 05 September 2018

Functional characterization of a novel mutation in NKX2-5 associated with congenital heart disease and adult-onset cardiomyopathy.

scientific article published on 09 May 2013

GATA4 mutations in 357 unrelated patients with congenital heart malformation

scientific article

Identification of an Spl-like element within the immunoglobulin kappa 3' enhancer necessary for maximal enhancer activity.

scientific article

Metformin intervention prevents cardiac dysfunction in a murine model of adult congenital heart disease

scientific article published on 15 November 2018

Microarray profiling to analyse adult cardiac fibroblast identity

scientific article

Molecular analysis ofPRKAG2,LAMP2, andNKX2-5genes in a cohort of 125 patients with accessory atrioventricular connection

article

Mutations in cardiac T-box factor gene TBX20 are associated with diverse cardiac pathologies, including defects of septation and valvulogenesis and cardiomyopathy

scientific article

NKX2-5 regulates human cardiomyogenesis via a HEY2 dependent transcriptional network

scientific article published on 10 April 2018

Point mutations in murine Nkx2-5 phenocopy human congenital heart disease and induce pathogenic Wnt signaling.

scientific article

The cardiac fibroblast: Origin, identity and role in homeostasis and disease.

scientific article

Transcription factor protein interactomes reveal genetic determinants in heart disease

scientific article published in March 2022

VISIONET: intuitive visualisation of overlapping transcription factor networks, with applications in cardiogenic gene discovery.

scientific article published on May 2015

Voltage dependence of macroscopic and unitary currents of gap junction channels formed by mouse connexin50 expressed in rat neuroblastoma cells.

scientific article published in June 1999

List of works by Mauro W Costa

A novel conditional mouse model for Nkx2-5 reveals transcriptional regulation of cardiac ion channels.

A tyrosine-rich domain within homeodomain transcription factor Nkx2-5 is an essential element in the early cardiac transcriptional regulatory machinery

CARFMAP: A Curated Pathway Map of Cardiac Fibroblasts

Cardiac T-box factor Tbx20 directly interacts with Nkx2-5, GATA4, and GATA5 in regulation of gene expression in the developing heart

Cardiogenic genes expressed in cardiac fibroblasts contribute to heart development and repair

Complex SUMO-1 regulation of cardiac transcription factor Nkx2-5

Conformational stability and DNA binding specificity of the cardiac T-box transcription factor Tbx20.

Deletion of Nkx2-5 in trabecular myocardium reveals the developmental origins of pathological heterogeneity associated with ventricular non-compaction cardiomyopathy

DuOx2 Promoter Regulation by Hormones, Transcriptional Factors and the Coactivator TAZ.

Effect of oxygen on cardiac differentiation in mouse iPS cells: role of hypoxia inducible factor-1 and Wnt/beta-catenin signaling

Enhancing the efficacy of glycolytic blockade in cancer cells via RAD51 inhibition

Functional characterization of a novel mutation in NKX2-5 associated with congenital heart disease and adult-onset cardiomyopathy.

GATA4 mutations in 357 unrelated patients with congenital heart malformation

Identification of an Spl-like element within the immunoglobulin kappa 3' enhancer necessary for maximal enhancer activity.

Metformin intervention prevents cardiac dysfunction in a murine model of adult congenital heart disease

Microarray profiling to analyse adult cardiac fibroblast identity

Molecular analysis ofPRKAG2,LAMP2, andNKX2-5genes in a cohort of 125 patients with accessory atrioventricular connection

Mutations in cardiac T-box factor gene TBX20 are associated with diverse cardiac pathologies, including defects of septation and valvulogenesis and cardiomyopathy

NKX2-5 regulates human cardiomyogenesis via a HEY2 dependent transcriptional network

Point mutations in murine Nkx2-5 phenocopy human congenital heart disease and induce pathogenic Wnt signaling.

The cardiac fibroblast: Origin, identity and role in homeostasis and disease.

Transcription factor protein interactomes reveal genetic determinants in heart disease

VISIONET: intuitive visualisation of overlapping transcription factor networks, with applications in cardiogenic gene discovery.

Voltage dependence of macroscopic and unitary currents of gap junction channels formed by mouse connexin50 expressed in rat neuroblastoma cells.