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List of works by Jean-Luc Desseyn

(n-3) long-chain PUFA differentially affect resistance to Pseudomonas aeruginosa infection of male and female cftr-/- mice.

scientific article published on 27 April 2011

A lipoxygenase with dual positional specificity is expressed in olives (Olea europaea L.) during ripening.

scientific article published on May 2009

Abnormal expression of Muc5b in Cftr-null mice and in mammary tumors of MMTV-ras mice.

scientific article

Architecture of the large membrane-bound mucins.

scientific article published on 28 December 2007

Assembly of the respiratory mucin MUC5B: a new model for a gel-forming mucin

scientific article published on 28 April 2014

Biological modeling of mucus to modulate mucus barriers

scientific article published on 10 December 2015

Characterization of mouse muc6 and evidence of conservation of the gel-forming mucin gene cluster between human and mouse.

scientific article published in April 2003

Cloning, chromosomal localization and characterization of the murine mucin gene orthologous to human MUC4.

scientific article

Delivery of a mucin domain enriched in cysteine residues strengthens the intestinal mucous barrier

scientific article published on 14 May 2015

Dietary (n-3) polyunsaturated fatty acids affect the kinetics of pro- and antiinflammatory responses in mice with Pseudomonas aeruginosa lung infection

scientific article published on 03 December 2008

Dietary pectin-derived acidic oligosaccharides improve the pulmonary bacterial clearance of Pseudomonas aeruginosa lung infection in mice by modulating intestinal microbiota and immunity.

scientific article

Early life nutrition influences susceptibility to chronic inflammatory colitis in later life

scientific article published on 02 December 2019

Early-life origin of intestinal inflammatory disorders.

scientific article published on 7 March 2017

Epigenetic regulation (DNA methylation, histone modifications) of the 11p15 mucin genes (MUC2, MUC5AC, MUC5B, MUC6) in epithelial cancer cells.

scientific article published on 30 April 2007

Evolution of the large secreted gel-forming mucins

scientific article published on 01 August 2000

Evolutionary history of the 11p15 human mucin gene family

scientific article published on 01 January 1998

Expression of a nonmyristylated variant of the catalytic subunit of protein kinase A during male germ-cell development.

scientific article published on June 2000

Gel-forming mucin interactome drives mucus viscoelasticity.

scientific article published on 28 December 2017

Genomic organization of the 3′-region of the human MUC5AC mucin gene: additional evidence for a common ancestral gene for the 11p15.5 mucin gene family ⬇️

scientific article published on June 15, 1998

Genomic organization of the human mucin gene MUC5B. cDNA and genomic sequences upstream of the large central exon

scientific article

Human mucin gene MUC5B, the 10.7-kb large central exon encodes various alternate subdomains resulting in a super-repeat. Structural evidence for a 11p15.5 gene family.

scientific article

Identification of a 42-kDa nuclear factor (NF1-MUC5B) from HT-29 MTX cells that binds to the 3' region of human mucin gene MUC5B.

scientific article

Impact and consequences of intensive chemotherapy on intestinal barrier and microbiota in acute myeloid leukemia: the role of mucosal strengthening

scientific article published on 01 November 2020

Impact of fish oils on the outcomes of a mouse model of acute Pseudomonas aeruginosa pulmonary infection.

scientific article published on 7 January 2015

In vivo imaging of the Muc5b gel-forming mucin

scientific article

Long-term dietary (n-3) polyunsaturated fatty acids show benefits to the lungs of Cftr F508del mice.

scientific article

MUC5B leads to aggressive behavior of breast cancer MCF7 cells.

scientific article

Modulation of host defence against bacterial and viral infections by omega-3 polyunsaturated fatty acids

scientific article

Muc5b is mainly expressed and sialylated in the nasal olfactory epithelium whereas Muc5ac is exclusively expressed and fucosylated in the nasal respiratory epithelium

scientific article published on 27 April 2019

Muc5b-deficient mice develop early histological lung abnormalities

scientific article published on 07 November 2019

Mucin CYS domain stiffens the mucus gel hindering bacteria and spermatozoa

scientific article published on 18 November 2019

Non-C-mannosylable mucin CYS domains hindered proper folding and secretion of mucin

scientific article published on 30 October 2018

Ocular mucins in dry eye disease

scientific article published on 17 July 2019

Omega-3 polyunsaturated fatty acids improve host response in chronic Pseudomonas aeruginosa lung infection in mice

article

Pectin-Derived Acidic Oligosaccharides Improve the Outcome of Pseudomonas aeruginosa Lung Infection in C57BL/6 Mice

scientific article published on 23 November 2015

Preclinical mouse model to monitor live Muc5b-producing conjunctival goblet cell density under pharmacological treatments

scientific article

Systematic gene overexpression in Candida albicans identifies a regulator of early adaptation to the mammalian gut

article

The Cervicovaginal Mucus Barrier

scientific article published on 04 November 2020

The characterization of the first anti-mouse Muc6 antibody shows an increased expression of the mucin in pancreatic tissue of Cftr-knockout mice

scientific article published on 23 March 2010

The extraordinarily complex but highly structured organization of intestinal mucus-gel unveiled in multicolor images

scientific article

The mucin MUC4 and its membrane partner ErbB2 regulate biological properties of human CAPAN-2 pancreatic cancer cells via different signalling pathways

scientific article

Transgenic Mouse Reporter to Study Muc5b In Vivo

scientific article published on 01 November 2018

[Custom modification in vivo of mucus properties: proof of concept and potential applications].

scientific article published on 16 December 2015

[Gel-forming mucins structure governs mucus gels viscoelasticity]

scientific article published on 01 October 2018

[MUC genes: a superfamily of genes? Towards a functional classification of human apomucins]

scientific article published on 01 January 1999

[Mucous cell differentiation and regulation of the gelling mucin Muc5b: a new tool for ex vivo and in vivo preclinical studies]

scientific article published on 01 May 2017

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