List of works - Arnaud Mourier

A Phenotype-Driven Approach to Generate Mouse Models with Pathogenic mtDNA Mutations Causing Mitochondrial Disease.

scientific article published on September 2016

A novel histochemistry assay to assess and quantify focal cytochrome c oxidase deficiency.

scientific article published on 16 April 2018

A tissue-specific approach to the analysis of metabolic changes in Caenorhabditis elegans

scientific article (publication date: 2011)

Active proton leak in mitochondria: a new way to regulate substrate oxidation.

scientific article published on 6 November 2009

Adipose tissue mitochondrial dysfunction triggers a lipodystrophic syndrome with insulin resistance, hepatosteatosis, and cardiovascular complications

scientific article

Adipose-specific deletion of TFAM increases mitochondrial oxidation and protects mice against obesity and insulin resistance

scientific article published on 15 November 2012

Base-excision repair deficiency alone or combined with increased oxidative stress does not increase mtDNA point mutations in mice

scientific article published on 01 July 2018

Bioenergetic roles of mitochondrial fusion.

scientific article published on 06 April 2016

CLUH regulates mitochondrial metabolism by controlling translation and decay of target mRNAs

scientific article published on 10 February 2017

COX7A2L Is a Mitochondrial Complex III Binding Protein that Stabilizes the III2+IV Supercomplex without Affecting Respirasome Formation.

scientific article published on 17 August 2016

Changes of mitochondrial ultrastructure and function during ageing in mice and Drosophila

scientific article published on 12 July 2017

Dietary methionine deficiency affects oxidative status, mitochondrial integrity and mitophagy in the liver of rainbow trout (Oncorhynchus mykiss).

scientific article published on 5 July 2018

Drosophila melanogaster LRPPRC2 is involved in coordination of mitochondrial translation

scientific article

Germline mitochondrial DNA mutations aggravate ageing and can impair brain development

scientific article published on 21 August 2013

Glycerol supports growth of the Trypanosoma brucei bloodstream forms in the absence of glucose: Analysis of metabolic adaptations on glycerol-rich conditions

scientific article published on 01 November 2018

Hierarchical RNA Processing Is Required for Mitochondrial Ribosome Assembly.

scientific article published on 3 August 2016

Human COX7A2L Regulates Complex III Biogenesis and Promotes Supercomplex Organization Remodeling without Affecting Mitochondrial Bioenergetics

scientific article published on 01 November 2018

Intra-mitochondrial Methylation Deficiency Due to Mutations in SLC25A26

scientific journal article

Kinetic activation of yeast mitochondrial D-lactate dehydrogenase by carboxylic acids.

scientific article published on 20 June 2008

Loss of LRPPRC causes ATP synthase deficiency

scientific article published on 6 January 2014

Loss of UCP2 attenuates mitochondrial dysfunction without altering ROS production and uncoupling activity

scientific article (publication date: June 2014)

MICOS coordinates with respiratory complexes and lipids to establish mitochondrial inner membrane architecture.

scientific article published on 28 April 2015

MTERF1 binds mtDNA to prevent transcriptional interference at the light-strand promoter but is dispensable for rRNA gene transcription regulation

scientific journal article

MTERF3 regulates mitochondrial ribosome biogenesis in invertebrates and mammals

scientific article

Mitochondrial adaptations to steatohepatitis induced by a methionine- and choline-deficient diet.

scientific article published on 6 November 2007

Mitochondrial fusion is required for regulation of mitochondrial DNA replication

scientific article published on 06 June 2019

Mitofusin 2 is necessary for striatal axonal projections of midbrain dopamine neurons

scientific article published on 21 August 2012

Mitofusin 2 is required to maintain mitochondrial coenzyme Q levels.

scientific article

POLRMT does not transcribe nuclear genes.

scientific article published in October 2014

POLRMT regulates the switch between replication primer formation and gene expression of mammalian mtDNA.

scientific article published on 05 August 2016

Rescue of primary ubiquinone deficiency due to a novel COQ7 defect using 2,4-dihydroxybensoic acid.

scientific article

Role of the mitochondrial protein LRPPRC2 in Drosophila melanogaster

SLIRP Regulates the Rate of Mitochondrial Protein Synthesis and Protects LRPPRC from Degradation

scientific article published on 6 August 2015

Succinate dehydrogenase upregulation destabilize complex I and limits the lifespan of gas-1 mutant

scientific article

The bicoid stability factor controls polyadenylation and expression of specific mitochondrial mRNAs in Drosophila melanogaster

scientific article

The respiratory chain supercomplex organization is independent of COX7a2l isoforms

scientific article

Tracing the trail of protons through complex I of the mitochondrial respiratory chain

scientific article

Transcriptomic and proteomic landscape of mitochondrial dysfunction reveals secondary coenzyme Q deficiency in mammals

scientific article published on 14 November 2017

Variation in germline mtDNA heteroplasmy is determined prenatally but modified during subsequent transmission

scientific article

List of works by Arnaud Mourier

A Phenotype-Driven Approach to Generate Mouse Models with Pathogenic mtDNA Mutations Causing Mitochondrial Disease.

A novel histochemistry assay to assess and quantify focal cytochrome c oxidase deficiency.

A tissue-specific approach to the analysis of metabolic changes in Caenorhabditis elegans

Active proton leak in mitochondria: a new way to regulate substrate oxidation.

Adipose tissue mitochondrial dysfunction triggers a lipodystrophic syndrome with insulin resistance, hepatosteatosis, and cardiovascular complications

Adipose-specific deletion of TFAM increases mitochondrial oxidation and protects mice against obesity and insulin resistance

Base-excision repair deficiency alone or combined with increased oxidative stress does not increase mtDNA point mutations in mice

Bioenergetic roles of mitochondrial fusion.

CLUH regulates mitochondrial metabolism by controlling translation and decay of target mRNAs

COX7A2L Is a Mitochondrial Complex III Binding Protein that Stabilizes the III2+IV Supercomplex without Affecting Respirasome Formation.

Changes of mitochondrial ultrastructure and function during ageing in mice and Drosophila

Dietary methionine deficiency affects oxidative status, mitochondrial integrity and mitophagy in the liver of rainbow trout (Oncorhynchus mykiss).

Drosophila melanogaster LRPPRC2 is involved in coordination of mitochondrial translation

Germline mitochondrial DNA mutations aggravate ageing and can impair brain development

Glycerol supports growth of the Trypanosoma brucei bloodstream forms in the absence of glucose: Analysis of metabolic adaptations on glycerol-rich conditions

Hierarchical RNA Processing Is Required for Mitochondrial Ribosome Assembly.

Human COX7A2L Regulates Complex III Biogenesis and Promotes Supercomplex Organization Remodeling without Affecting Mitochondrial Bioenergetics

Intra-mitochondrial Methylation Deficiency Due to Mutations in SLC25A26

Kinetic activation of yeast mitochondrial D-lactate dehydrogenase by carboxylic acids.

Loss of LRPPRC causes ATP synthase deficiency

Loss of UCP2 attenuates mitochondrial dysfunction without altering ROS production and uncoupling activity

MICOS coordinates with respiratory complexes and lipids to establish mitochondrial inner membrane architecture.

MTERF1 binds mtDNA to prevent transcriptional interference at the light-strand promoter but is dispensable for rRNA gene transcription regulation

MTERF3 regulates mitochondrial ribosome biogenesis in invertebrates and mammals

Mitochondrial adaptations to steatohepatitis induced by a methionine- and choline-deficient diet.

Mitochondrial fusion is required for regulation of mitochondrial DNA replication

Mitofusin 2 is necessary for striatal axonal projections of midbrain dopamine neurons

Mitofusin 2 is required to maintain mitochondrial coenzyme Q levels.

POLRMT does not transcribe nuclear genes.

POLRMT regulates the switch between replication primer formation and gene expression of mammalian mtDNA.

Rescue of primary ubiquinone deficiency due to a novel COQ7 defect using 2,4-dihydroxybensoic acid.

Role of the mitochondrial protein LRPPRC2 in Drosophila melanogaster

SLIRP Regulates the Rate of Mitochondrial Protein Synthesis and Protects LRPPRC from Degradation

Succinate dehydrogenase upregulation destabilize complex I and limits the lifespan of gas-1 mutant

The bicoid stability factor controls polyadenylation and expression of specific mitochondrial mRNAs in Drosophila melanogaster

The respiratory chain supercomplex organization is independent of COX7a2l isoforms

Tracing the trail of protons through complex I of the mitochondrial respiratory chain

Transcriptomic and proteomic landscape of mitochondrial dysfunction reveals secondary coenzyme Q deficiency in mammals

Variation in germline mtDNA heteroplasmy is determined prenatally but modified during subsequent transmission