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List of works by Benny Chain

1-Integrins determine the dendritic morphology which enhances DC-SIGN-mediated particle capture by dendritic cells

scientific article published on 28 June 2006

A Linear Epitope in the N-Terminal Domain of CCR5 and Its Interaction with Antibody

scientific article published on June 2015

A cardinal role for cathepsin d in co-ordinating the host-mediated apoptosis of macrophages and killing of pneumococci.

scientific article

A cell-free model system for the study of antigen processing

scientific article published on 01 January 1989

A defect in bone marrow derived dendritic cell maturation in the nonobesediabetic mouse

scientific article published on 01 March 2001

A quantitative proteomics design for systematic identification of protease cleavage events.

scientific article published on 13 July 2010

Adherent human alveolar macrophages exhibit a transient pro-inflammatory profile that confounds responses to innate immune stimulation

scientific article

Adjuvant composition determines the induction of type II collagen-induced arthritis

scientific article published on 01 July 1992

An Economical, Quantitative, and Robust Protocol for High-Throughput T Cell Receptor Sequencing from Tumor or Blood

scientific article published on 01 January 2019

An immunodominant NP<sub>105-113</sub>-B*07:02 cytotoxic T cell response controls viral replication and is associated with less severe COVID-19 disease

scientific article published on 01 December 2021

Antigen presentation by dendritic cells provides optimal stimulation for the production of interleukin (IL) 2, IL 4 and interferon-gamma by allogeneic T cells

scientific article published on 01 November 1991

Antigen-specific inhibition of IL-2 and IL-3 production in contact sensitivity to TNP

Antimicrobial and cytotoxic activity of hypochlorous acid: interactions with taurine and nitrite

scientific article published on 01 June 2000

Autocrine type I interferon amplifies dendritic cell responses to lipopolysaccharide via the nuclear factor-kappaB/p38 pathways

scientific article published on 01 March 2006

Autologous apoptotic T cells interact with dendritic cells, but do not affect their surface phenotype or their ability to induce recall immune responses

scientific article published on 01 July 2003

Benchmarking of T cell receptor repertoire profiling methods reveals large systematic biases

scientific article published on 07 September 2020

Blood cells contribute to glial repair in an insect.

scientific article published in January 1987

Blood transcriptomic diagnosis of pulmonary and extrapulmonary tuberculosis

scientific article published on 06 October 2016

CD98-dependent homotypic aggregation is associated with translocation of protein kinase cδ and activation of mitogen-activated protein kinases ⬇️

scientific article published on May 15, 2003

Cancer of the cervix: prospects for immunological control ⬇️

scientific article published on April 1, 1991

Characterization of soluble factors from cultures of premalignant cervical epithelium

scientific article published on 01 January 1999

Characterization of the T Cell Response to Human Rhinovirus in Children: Implications for Understanding the Immunopathology of the Common Cold ⬇️

scientific article published on September 1, 1997

Chemical toxicity to keratinocytes triggers dendritic cell activation via an IL-1α path

scientific article published on 23 September 2011

Chemically modified antigen-presenting cells induce T lymphocyte allospecific hyporesponsiveness

scientific article published on 01 December 1991

Chromatographic analysis of the trinitrophenyl derivatives of insulin

scientific article published on 01 June 1988

Clinical T Cell Receptor Repertoire Deep Sequencing and Analysis: An Application to Monitor Immune Reconstitution Following Cord Blood Transplantation

scientific article published on 05 November 2018

Clonal expansion under the microscope: studying lymphocyte activation and differentiation using live-cell imaging

scientific article published on 26 November 2015

Computational analysis of stochastic heterogeneity in PCR amplification efficiency revealed by single molecule barcoding.

scientific article published on 13 October 2015

Conventional protein kinase C plays a critical role in negative regulation of CD98-induced homotypic aggregation.

scientific article published on 6 November 2009

Coupled IL-2-dependent extracellular feedbacks govern two distinct consecutive phases of CD4 T cell activation.

scientific article published on 15 November 2013

Current issues in antigen presentation--focus on the dendritic cell.

scientific article published on October 2003

DC priming by M. vaccae inhibits Th2 responses in contrast to specific TLR2 priming and is associated with selective activation of the CREB pathway

scientific article (publication date: April 2011)

Decombinator V4 - an improved AIRR-compliant software package for T cell receptor sequence annotation

scientific article published on 27 August 2020

Decombinator: a tool for fast, efficient gene assignment in T-cell receptor sequences using a finite state machine.

scientific article

Deletion of the virion host shutoff protein (vhs) from herpes simplex virus (HSV) relieves the viral block to dendritic cell activation: potential of vhs- HSV vectors for dendritic cell-mediated immunotherapy

scientific article

Dendritic cell activation and cytokine production induced by group B Neisseria meningitidis: interleukin-12 production depends on lipopolysaccharide expression in intact bacteria.

scientific article published in July 2001

Dendritic cells and myeloid leukaemias: plasticity and commitment in cell differentiation.

scientific article published on August 2007

Dendritic cells in viral pathogenesis: protective or defective?

scientific article

Dengue virus NS5 inhibits interferon-alpha signaling by blocking signal transducer and activator of transcription 2 phosphorylation.

scientific article

Determinants of anti-PD-1 response and resistance in clear cell renal cell carcinoma

scientific article published on 28 October 2021

Differential cytokine regulation by eicosanoids in T cells primed by contact sensitisation with TNP

scientific article published on 01 July 1993

Differential regulation of HLA-DQ expression by keratinocytes and Langerhans cells in normal and premalignant cervical epithelium

scientific article published on 01 September 1998

Differential regulation of cytokine production by nitric oxide

scientific article published on 01 September 1993

Differential requirement for cathepsin D for processing of the full length and C-terminal fragment of the malaria antigen MSP1.

scientific article

Directional migration of recirculating lymphocytes through lymph nodes via random walks

scientific article

Discordant neutralizing antibody and T cell responses in asymptomatic and mild SARS-CoV-2 infection

scientific article published on 01 December 2020

Does the T-cell receptor bind to the MHC?

scientific article published in October 1987

Dynamic Perturbations of the T-Cell Receptor Repertoire in Chronic HIV Infection and following Antiretroviral Therapy

scientific article

Editorial: Methods and Applications of Computational Immunology

scientific article published on 29 November 2019

Effect of taurine chloramine, the product of activated neutrophils, on the development of collagen-induced arthritis in DBA 1/J mice.

scientific article published in January 2002

Effects of oxidised low density lipoprotein on dendritic cells: a possible immunoregulatory component of the atherogenic micro-environment?

scientific article published on 01 September 2002

Endocytic Activity of Dendritic Cells is Similar to Other Antigen Presenting Cells ⬇️

scientific article published on 01 January 1993

Endocytosis by antigen presenting cells: dendritic cells are as endocytically active as other antigen presenting cells ⬇️

scientific article published on September 1, 1992

Endopeptidase activities associated with the plasma membrane compartment of an antigen-presenting B cell

scientific article published on 01 January 1989

Enhancement of CD4+ T-cell-dependent interleukin-2 production in vitro by murine alveolar macrophages: the role of leukotriene B4

scientific article published on 01 July 1997

Enhancement of immunogenic properties of ovalbumin as a result of its chlorination

scientific article published on 01 January 1991

Epitope Spreading Contributes to Effective Immunotherapy in Metastatic Melanoma Patients ⬇️

scientific article published on June 1, 2011

Epitope analysis of the T cell response to a complex antigen: proliferative responses to human rhinovirus capsids

scientific article published on 01 September 1993

Error, reproducibility and sensitivity: a pipeline for data processing of Agilent oligonucleotide expression arrays

scientific article

Exploring Carbon Nanomaterial Diversity for Nucleation of Protein Crystals. ⬇️

scientific article published on 4 February 2016

Expression and function of mixed lineage kinases in dendritic cells

scientific article published on 13 August 2007

Extension, retraction and contraction in the formation of a dendritic cell dendrite: distinct roles for Rho GTPases

scientific article published on 01 July 2002

Feature selection using a one dimensional naïve Bayes' classifier increases the accuracy of support vector machine classification of CDR3 repertoires

scientific article published on 10 January 2017

Framework engineering to produce dominant T cell receptors with enhanced antigen-specific function

scientific article published on 01 October 2019

From sentinel to messenger: an extended phenotypic analysis of the monocyte to dendritic cell transition

scientific article published on 01 August 1998

Further studies on the regulation of lymphokine biosynthesis in contact sensitivity

scientific article published on 01 September 1990

Glycoprotein-dependent and TLR2-independent innate immune recognition of herpes simplex virus-1 by dendritic cells.

scientific article

HIV-1 infection of macrophages dysregulates innate immune responses to Mycobacterium tuberculosis by inhibition of interleukin-10.

scientific article

Haematopoietic development and immunological function in the absence of cathepsin D.

scientific article

Herpes simplex virus infection of dendritic cells: balance among activation, inhibition, and immunity.

scientific article published on 6 January 2003

Herpes simplex virus type-1-induced activation of myeloid dendritic cells: the roles of virus cell interaction and paracrine type I IFN secretion.

scientific article published in September 2004

High-throughput sequencing of the T-cell receptor repertoire: pitfalls and opportunities

scientific article published on 10 January 2017

Human SARS-CoV-2 challenge uncovers local and systemic response dynamics

scientific article published on 19 June 2024

Hybrid epidemics--a case study on computer worm conficker ⬇️

scientific article published on 15 May 2015

Hybrid spreading mechanisms and T cell activation shape the dynamics of HIV-1 infection ⬇️

scientific article published in April 2015

Hypochlorous acid enhances immunogenicity and uptake of allogeneic ovarian tumor cells by dendritic cells to cross-prime tumor-specific T cells.

scientific article published on 4 February 2006

Hypochlorous acid: a natural adjuvant that facilitates antigen processing, cross-priming, and the induction of adaptive immunity

scientific article published on 16 December 2009

IFN-gamma down-regulates MHC expression and antigen processing in a human B cell line.

scientific article published on January 1999

Identification of Therapeutic Targets of Inflammatory Monocyte Recruitment to Modulate the Allogeneic Injury to Donor Cornea.

scientific article published on November 2015

Immune Tolerance Maintained by Cooperative Interactions between T Cells and Antigen Presenting Cells Shapes a Diverse TCR Repertoire

scientific article published on 7 August 2015

Immune response to human papillomavirus type 16 E6 gene in a live vaccinia vector.

scientific article

Immunization with a lentiviral vector stimulates both CD4 and CD8 T cell responses to an ovalbumin transgene.

scientific article published on 4 November 2005

Importin‐7 Mediates Nuclear Trafficking of DNA in Mammalian Cells ⬇️

scientific article published on November 7, 2012

Improvement of the in vitro T cell proliferation assay by a modified method that separates the antigen recognition and IL-2-dependent steps

scientific article published on 01 May 1987

In vivo priming of T cells against cryptic determinants by dendritic cells exposed to interleukin 6 and native antigen.

scientific article published on December 1998

Induction of CD4 T cell memory by local cellular collectivity

scientific article published on 01 June 2018

Induction of cytotoxic T lymphocytes with peptides in vitro: identification of candidate T-cell epitopes in human papilloma virus ⬇️

scientific article published on September 1, 1992

Information-Driven Docking for TCR-pMHC Complex Prediction

scientific article published on 09 June 2021

Inhibition of T-cell response by Escherichia coli heat-labile enterotoxin-treated epithelial cells.

scientific article published on December 2000

Instruction of naive CD4+ T cells by polarized CD4+ T cells within dendritic cell clusters.

scientific article published in June 2003

Is hepatitis C virus infection of dendritic cells a mechanism facilitating viral persistence?

scientific article

Is there a role for nitric oxide in regulation of T cell secretion of IL-2?

scientific article published on 01 June 1996

Isolation and N-terminal sequence determination of a novel gamma/delta T cell surface antigen

scientific article published on 01 June 1997

JNK activation limits dendritic cell maturation in response to reactive oxygen species by the induction of apoptosis.

scientific article published on 30 March 2005

LCPTP-MAP kinase interaction: permanent partners or transient associates?

scientific article published in November 2002

LIGHTing up dendritic cell activation: Immune regulation and viral exploitation.

scientific article

Lentiviral vectors transduce proliferating dendritic cell precursors leading to persistent antigen presentation and immunization.

scientific article published on 7 July 2009

Liposome-mediated delivery stimulates a class I-restricted cytotoxic T cell response to soluble antigen

scientific article published on 01 January 1992

Local cooperation dominates over competition between CD4+ T cells of different antigen/MHC specificity

scientific article published on 01 July 2003

Mannose-pepstatin conjugates as targeted inhibitors of antigen processing

scientific article published on 04 April 2006

Mechanisms for variability in a member of the scavenger-receptor cysteine-rich superfamily ⬇️

scientific article published on January 1, 1997

Mixed lineage kinases (MLKs): a role in dendritic cells, inflammation and immunity?

scientific article published on April 2007

Modulation of antigen-specific T-cell activation in vitro by taurine chloramine

scientific article published on 01 July 1998

Modulation of dendritic cell differentiation and cytokine secretion by the hydatid cyst fluid of Echinococcus granulosus.

scientific article published in June 2006

Modulation of dendritic cell endocytosis and antigen processing pathways by Escherichia coli heat-labile enterotoxin and mutant derivatives

scientific article published on 01 March 2003

Molecular Signatures of Regression of the Canine Transmissible Venereal Tumor.

scientific article published in April 2018

Molecular characterization of U937-dependent T-cell co-stimulation

scientific article published on 01 January 1999

Monocyte derived dendritic cells from HIV-1 infected individuals partially reconstitute CD4 T-cell responses

article

Multi-level regulation of lysosomal gene expression in lymphocytes.

scientific article published on August 1993

Natural cathepsin E deficiency in the immune system of C57BL/6J mice

scientific article published on 14 November 2007

Neoantigen-directed immune escape in lung cancer evolution

scientific article published on 20 March 2019

Neutrophil Myeloperoxidase: Soldier and Statesman ⬇️

scientific article published on 06 December 2011

Nitric oxide up-regulates the release of inflammatory mediators by mouse macrophages

scientific article published on 01 April 1995

Nonphagocytic dendritic cells are effective accessory cells for anti-mycobacterial responses in vitro

scientific article published on 01 March 1985

Novel molecular mechanisms of dendritic cell-induced T cell activation.

scientific article published in July 2000

Observations on the cytochemistry of the hemocytes of an insect, Galleria mellonella.

scientific article

Optimizing hybrid spreading in metapopulations ⬇️

scientific article published on 29 April 2015

Oxidation of ovarian epithelial cancer cells by hypochlorous acid enhances immunogenicity and stimulates T cells that recognize autologous primary tumor.

scientific article

Oxidative modification of type II collagen differentially affects its arthritogenic and tolerogenic capacity in experimental arthritis

scientific article published on 01 July 2004

PD1-Expressing T Cell Subsets Modify the Rejection Risk in Renal Transplant Patients

scientific article published on 11 April 2016

Penicillin and beyond.

scientific article published in October 1991

Placentally derived prostaglandin E2 acts via the EP4 receptor to inhibit IL-2-dependent proliferation of CTLL-2 T cells

scientific article

Plasticity of the Immune System in Children Following Treatment Interruption in HIV-1 Infection

scientific article published on 29 July 2021

Pre-clinical assessment of autologous DC-based therapy in ovarian cancer patients with progressive disease

scientific article

Predicting T Cell Receptor Antigen Specificity From Structural Features Derived From Homology Models of Receptor-Peptide-Major Histocompatibility Complexes

scientific article published on 08 September 2021

Presentation by peritoneal macrophages: modulation by antibody-antigen complexes

scientific article published on 01 May 1986

Prostaglandin E2 (PGE2) differentially regulates the production of IL-2 and IL-3 by murine immune T-cells

scientific article published on 01 January 1992

Protein degradation in MHC class II antigen presentation: opportunities for immunomodulation.

scientific article published in June 2000

Proteomic evaluation and validation of cathepsin D regulated proteins in macrophages exposed to Streptococcus pneumoniae

scientific article

Publisher Correction: Spatial heterogeneity of the T cell receptor repertoire reflects the mutational landscape in lung cancer

scientific article published on 03 June 2020

Quantifying changes in the T cell receptor repertoire during thymic development

scientific article published in 2023

Quantitative Characterization of the T Cell Receptor Repertoire of Naïve and Memory Subsets Using an Integrated Experimental and Computational Pipeline Which Is Robust, Economical, and Versatile

scientific article published on 12 October 2017

Quantitative analysis of the T cell receptor repertoire

scientific article published on 20 June 2019

Quantitative imaging assay for NF-kappaB nuclear translocation in primary human macrophages.

scientific article published on 20 November 2007

Reactive oxygen species activate human peripheral blood dendritic cells

scientific article published on 01 January 1999

Regulation of CYP27B1 and CYP24A1 hydroxylases limits cell-autonomous activation of vitamin D in dendritic cells.

scientific article published on 10 April 2014

Regulation of in vitro release of TH2 type cytokines (IL-4, IL-6) in the T cell response to the trinitrophenyl (TNP) hapten

scientific article published on 01 February 1993

Regulation of murine dendritic cell functions in vitro by taurine chloramine, a major product of the neutrophil myeloperoxidase-halide system

scientific article published on 01 November 1999

Regulation of primary HIV-1 isolate replication in dendritic cells.

scientific article published on January 2002

Ribotoxic stress activates p38 and JNK kinases and modulates the antigen-presenting activity of dendritic cells.

scientific article

Role of DNA topology in uptake of polyplex molecules by dendritic cells

scientific article published on 13 January 2012

Self/nonself discrimination among immunoregulatory (CD4) T cells.

scientific article published in June 2000

Sensitization of allo-specific T lymphocytes in vivo: role of antigen-presenting cells

scientific article published on 01 November 1992

Spatial heterogeneity of the T cell receptor repertoire reflects the mutational landscape in lung cancer

scientific article published on 07 October 2019

Specificity, Privacy, and Degeneracy in the CD4 T Cell Receptor Repertoire Following Immunization

scientific article

Strategies for studying mouse and human immune responses to human papillomavirus type 16.

scientific article published in January 1994

Structural relationships and cellular tropism of staphylococcal superantigen-like proteins.

scientific article published on July 2004

Suppression of lymphokine production in anti-minor histocompatibility antigen responses ⬇️

scientific article published on January 1, 1991

T cell receptor sequence clustering and antigen specificity

scientific article published on 05 August 2020

Targeted delivery of antigen processing inhibitors to antigen presenting cells via mannose receptors.

scientific article

Temperature-induced stress abrogates co-stimulatory function in antigen-presenting cells

scientific article published on 01 November 1991

The "Achilles Heel" of Cancer and Its Implications for the Development of Novel Immunotherapeutic Strategies.

scientific article

The T Cell Response to the Contact Sensitizer Paraphenylenediamine Is Characterized by a Polyclonal Diverse Repertoire of Antigen-Specific Receptors.

scientific article published on 16 February 2017

The T cell differentiation landscape is shaped by tumour mutations in lung cancer

scientific article published on 22 May 2020

The T-cell response to haptenated insulins. I. The proliferative response.

scientific article published in January 1989

The T-cell response to haptenated insulins. II. The antibody response.

scientific article published in January 1989

The effects of auranofin on activation and interleukin-2 release from human peripheral blood mononuclear cells

scientific article published on 01 November 1993

The functional consequences of delivery of HIV-1 Nef to dendritic cells using an adenoviral vector.

scientific article published in January 2004

The gold anti-rheumatic drug auranofin governs T cell activation by enhancing oxygen free radical production

scientific article published on 01 September 1994

The immune system as a biomonitor: explorations in innate and adaptive immunity.

scientific article published on April 2013

The impact of DNA topology on polyplex uptake and transfection efficiency in mammalian cells.

scientific article

The interaction between staphylococcal superantigen-like proteins and human dendritic cells

scientific article published on 01 June 2005

The interaction of auranofin and buthionine sulfoximine blocks activation of human peripheral T lymphocytes

scientific article published on 01 November 1993

The naive T-cell receptor repertoire has an extremely broad distribution of clone sizes

scientific article published on 18 March 2020

The role of dendritic cells as co-stimulators in tolerance induction

scientific article published on 01 January 1993

The role of dendritic cells in the regulation of T cell cytokine synthesis

scientific article published on 01 January 1993

The role of non-adhesive T-cell-accessory cell interactions in the induction of T-cell proliferative hyporesponsiveness.

scientific article published on April 1994

The role of reactive oxygen species in triggering proliferation and IL-2 secretion in T cells

scientific article published on 01 January 1999

The sequence of sequencers: The history of sequencing DNA

scientific article

The stimulation of IL-2 production by anti-rheumatic drugs.

scientific article published in July 1989

The use of targeted microbeads for quantitative analysis of the phagocytic properties of human monocyte-derived dendritic cells.

scientific article published on 19 December 2004

Tracking global changes induced in the CD4 T cell receptor repertoire by immunization with a complex antigen using short stretches of CDR3 protein sequence

Tracking global changes induced in the CD4 T-cell receptor repertoire by immunization with a complex antigen using short stretches of CDR3 protein sequence

scientific article

Transcriptional Profiling of Endobronchial Ultrasound-Guided Lymph Node Samples Aids Diagnosis of Mediastinal Lymphadenopathy

scientific article published on 13 August 2015

Transcriptional profiling of innate and adaptive human immune responses to mycobacteria in the tuberculin skin test.

scientific article published on 30 August 2011

Tumor-associated E6 protein of human papillomavirus type 16 contains an unusual H-2Kb-restricted cytotoxic T cell epitope.

scientific article published on December 1995

Understanding HSV-1 entry glycoproteins.

scientific article published on May 2007

Urine-derived lymphocytes as a non-invasive measure of the bladder tumor immune microenvironment

scientific article published on 26 September 2018

Validation of Immune Cell Modules in Multicellular Transcriptomic Data.

scientific article

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