List of works - Jingbo Pi

(S)-α-chlorohydrin inhibits protein tyrosine phosphorylation through blocking cyclic AMP - protein kinase A pathway in spermatozoa.

scientific article

A systems biology perspective on Nrf2-mediated antioxidant response

scientific article

Acquisition of apoptotic resistance in cadmium-transformed human prostate epithelial cells: Bcl-2 overexpression blocks the activation of JNK signal transduction pathway

scientific article published in July 2007

Activation of NRF2 ameliorates oxidative stress and cystogenesis in autosomal dominant polycystic kidney disease

scientific article published on 01 July 2020

Activation of Nrf2-mediated oxidative stress response in macrophages by hypochlorous acid

scientific article published on 26 September 2007

Acute stimulation of white adipocyte respiration by PKA-induced lipolysis

scientific article published on 3 August 2010

Adaptive Posttranslational Control in Cellular Stress Response Pathways and Its Relationship to Toxicity Testing and Safety Assessment

scientific article

Adipose deficiency of Nrf2 in ob/ob mice results in severe metabolic syndrome

scientific article published on 13 December 2012

An overview of chemical inhibitors of the Nrf2-ARE signaling pathway and their potential applications in cancer therapy

scientific article published on 12 September 2016

Arsenic Induces p62 Expression to Form a Positive Feedback Loop with Nrf2 in Human Epidermal Keratinocytes: Implications for Preventing Arsenic-Induced Skin Cancer

scientific article (publication date: 24 January 2017)

Arsenic-induced malignant transformation of human keratinocytes: involvement of Nrf2

scientific article

Association between arsenic suppression of adipogenesis and induction of CHOP10 via the endoplasmic reticulum stress response

scientific article published on 5 December 2012

CNC-bZIP protein Nrf1-dependent regulation of glucose-stimulated insulin secretion

scientific article

Cadmium-induced malignant transformation in rat liver cells: role of aberrant oncogene expression and minimal role of oxidative stress.

scientific article

Comparative Study on In Vitro Culture of Mouse Bone Marrow Mesenchymal Stem Cells.

scientific article

Constitutive role for IRE1α-XBP1 signaling pathway in the insulin-mediated hepatic lipogenic program

scientific article

Correction to "Proteomic Characterization of the Cellular Response to Nitrosative Stress Mediated by S-Nitrosoglutathione Reductase Inhibition".

scientific article

Cross-regulations among NRFs and KEAP1 and effects of their silencing on arsenic-induced antioxidant response and cytotoxicity in human keratinocytes

scientific article published on 3 January 2012

Curcumin protects human keratinocytes against inorganic arsenite-induced acute cytotoxicity through an NRF2-dependent mechanism

scientific article published on 21 April 2013

Decreased enzyme activity of hepatic thioredoxin reductase and glutathione reductase in rabbits by prolonged exposure to inorganic arsenate.

scientific article published in October 2003

Deficiency in the nuclear factor E2-related factor 2 renders pancreatic β-cells vulnerable to arsenic-induced cell damage

scientific article

Deficiency in the nuclear factor E2-related factor-2 transcription factor results in impaired adipogenesis and protects against diet-induced obesity

scientific article

Deficiency of long isoforms of Nfe2l1 sensitizes MIN6 pancreatic β cells to arsenite-induced cytotoxicity.

scientific article

Divergent effects of sulforaphane on basal and glucose-stimulated insulin secretion in β-cells: role of reactive oxygen species and induction of endogenous antioxidants

scientific article published on 07 March 2013

Dose-dependent transitions in Nrf2-mediated adaptive response and related stress responses to hypochlorous acid in mouse macrophages

scientific article published on 17 April 2009

Drinking water disinfection byproduct iodoacetic acid induces tumorigenic transformation of NIH3T3 cells.

scientific article published on 21 May 2013

Effects of Nrf2 deficiency on arsenic metabolism in mice

scientific article published on 3 November 2017

Enhanced p62-NRF2 Feedback Loop due to Impaired Autophagic Flux Contributes to Arsenic-Induced Malignant Transformation of Human Keratinocytes

scientific article published on 30 October 2019

Evaluation of DNA damage in patients with arsenic poisoning: urinary 8-hydroxydeoxyguanine.

scientific article

Evaluation of the association between arsenic and diabetes: a National Toxicology Program workshop review

scientific article

Evidence for induction of oxidative stress caused by chronic exposure of Chinese residents to arsenic contained in drinking water

scientific article

Gene deficiency of glutathione S-transferase mu isoform associated with susceptibility to lung cancer in a Chinese population

scientific article published on 01 February 1997

Hormesis and adaptive cellular control systems

scientific article published on 19 March 2008

Identification of Nrf2-dependent airway epithelial adaptive response to proinflammatory oxidant-hypochlorous acid challenge by transcription profiling

scientific article published on 21 December 2007

Identification of novel NRF2-regulated genes by ChIP-Seq: influence on retinoid X receptor alpha.

scientific article

Induction of heme oxygenase 1 by arsenite inhibits cytokine-induced monocyte adhesion to human endothelial cells

scientific article

Iodoacetic Acid Activates Nrf2-Mediated Antioxidant Response in Vitro and in Vivo

article

Isoniazid suppresses antioxidant response element activities and impairs adipogenesis in mouse and human preadipocytes

scientific article published on 12 October 2013

Keap1 silencing boosts lipopolysaccharide-induced transcription of interleukin 6 via activation of nuclear factor κB in macrophages

scientific article published on 29 July 2013

Long isoforms of NRF1 contribute to arsenic-induced antioxidant response in human keratinocytes

scientific article

Low level, long-term inorganic arsenite exposure causes generalized resistance to apoptosis in cultured human keratinocytes: potential role in skin co-carcinogenesis.

scientific article

Low-level arsenic impairs glucose-stimulated insulin secretion in pancreatic beta cells: involvement of cellular adaptive response to oxidative stress

scientific article

Mathematical modeling reveals quantitative properties of KEAP1-NRF2 signaling

scientific article published in 2021

Mechanisms controlling the multistage post-translational processing of endogenous Nrf1α/TCF11 proteins to yield distinct isoforms within the coupled positive and negative feedback circuits

scientific article published on 01 October 2018

Metabolic syndrome and urinary cGMP excretion in general population

scientific article published on 24 March 2006

Metallothionein blocks oxidative DNA damage in vitro.

scientific article published on 23 August 2012

Molecular mechanism of human Nrf2 activation and degradation: role of sequential phosphorylation by protein kinase CK2.

scientific article

Myeloid lineage-specific deletion of antioxidant system enhances tumor metastasis.

scientific article

NRF2 Is a Potential Modulator of Hyperresistance to Arsenic Toxicity in Stem-Like Keratinocytes

scientific article published on 10 September 2017

Nrf1 CNC-bZIP protein promotes cell survival and nucleotide excision repair through maintaining glutathione homeostasis.

scientific article

Nrf1 is time-dependently expressed and distributed in the distinct cell types after trauma to skeletal muscles in rats

scientific article published on 28 January 2013

Nrf2 Improves Leptin and Insulin Resistance Provoked by Hypothalamic Oxidative Stress.

scientific article

Nrf2 deficiency aggravates the kidney injury induced by subacute cadmium exposure in mice

scientific article published on 04 January 2021

Nrf2 in alcoholic liver disease

scientific article published on 27 August 2018

Nrf2 in keratinocytes protects against skin fibrosis via regulating epidermal lesion and inflammatory response

scientific article published on 04 February 2020

Nrf2 protects pancreatic β-cells from oxidative and nitrosative stress in diabetic model mice

scientific article published in November 2013

Nrf2-Mediated Regulation of Skeletal Muscle Glycogen Metabolism

scientific article

Nuclear factor erythroid-derived factor 2-related factor 2 regulates transcription of CCAAT/enhancer-binding protein β during adipogenesis

scientific article published on 28 October 2011

Organic extract contaminants from drinking water activate Nrf2-mediated antioxidant response in a human cell line

scientific article published on 19 April 2013

Persistent oxidative stress due to absence of uncoupling protein 2 associated with impaired pancreatic beta-cell function

scientific article

Phase I to II cross-induction of xenobiotic metabolizing enzymes: a feedforward control mechanism for potential hormetic responses

scientific article

Prolonged exposure to insulin suppresses mitochondrial production in primary hepatocytes

scientific article

Prolonged inorganic arsenite exposure suppresses insulin-stimulated AKT S473 phosphorylation and glucose uptake in 3T3-L1 adipocytes: involvement of the adaptive antioxidant response

scientific article

Protective Role of Nuclear Factor E2-Related Factor 2 against Acute Oxidative Stress-Induced Pancreatic β -Cell Damage.

scientific article published on 9 April 2015

Proteomic characterization of the cellular response to nitrosative stress mediated by s-nitrosoglutathione reductase inhibition.

scientific article published on 19 March 2012

ROS signaling, oxidative stress and Nrf2 in pancreatic beta-cell function

scientific article

Reactive Oxygen Species and Antioxidants in Pancreatic β-Cell Function – Yin and Yang

Reactive oxygen species and uncoupling protein 2 in pancreatic β-cell function.

scientific article published on October 2010

Reactive oxygen species as a signal in glucose-stimulated insulin secretion

scientific article

Recent advances in 2D and 3D in vitro systems using primary hepatocytes, alternative hepatocyte sources and non-parenchymal liver cells and their use in investigating mechanisms of hepatotoxicity, cell signaling and ADME.

scientific article published on 23 August 2013

Reduced antioxidant capacity and diet-induced atherosclerosis in uncoupling protein-2-deficient mice

scientific article

Regulatory role of KEAP1 and NRF2 in PPARγ expression and chemoresistance in human non-small-cell lung carcinoma cells

scientific article

Relationship between urinary cGMP excretion and serum total cholesterol levels in a general population

scientific article

Serum antioxidant vitamins and risk of lung and stomach cancers in Shenyang, China ⬇️

scientific article published on July 17, 1998

Strain differences in arsenic-induced oxidative lesion via arsenic biomethylation between C57BL/6J and 129X1/SvJ mice

scientific article published on 17 March 2017

Suppression of NRF2-ARE activity sensitizes chemotherapeutic agent-induced cytotoxicity in human acute monocytic leukemia cells

scientific article published on 18 December 2015

The NRF2-mediated oxidative stress response pathway is associated with tumor cell resistance to arsenic trioxide across the NCI-60 panel.

scientific article

The impairment of glucose-stimulated insulin secretion in pancreatic β-cells caused by prolonged glucotoxicity and lipotoxicity is associated with elevated adaptive antioxidant response.

scientific article

The role of nuclear factor E2-Related factor 2 and uncoupling protein 2 in glutathione metabolism: Evidence from an in vivo gene knockout study.

scientific article published on 21 July 2016

Time-dependent expression and distribution of monoacylglycerol lipase during the skin-incised wound healing in mice

scientific article published on 08 April 2011

Transcription factor Nrf2 activation by inorganic arsenic in cultured keratinocytes: involvement of hydrogen peroxide

scientific article

Triptolide enhances chemotherapeutic efficacy of antitumor drugs in non-small-cell lung cancer cells by inhibiting Nrf2-ARE activity

scientific article published on 06 September 2018

Urinary arsenic speciation and its correlation with 8-OHdG in Chinese residents exposed to arsenic through coal burning.

scientific article published on 25 June 2008

Urinary cyclic GMP excretion and blood pressure levels in a general population

scientific article

Vascular dysfunction in patients with chronic arsenosis can be reversed by reduction of arsenic exposure

scientific article

[A study on relationship between glutathione S-transferase mu gene deletion and senile cataract susceptibility]

scientific article published on 01 May 1996

[Protective effects of exogenous superoxide dismutase on rabbit retinal injury by acute intraocular hypertension]

scientific article published on 01 November 1997

p62/Sqstm1 promotes malignancy of HCV-positive hepatocellular carcinoma through Nrf2-dependent metabolic reprogramming

scientific article

List of works by Jingbo Pi

(S)-α-chlorohydrin inhibits protein tyrosine phosphorylation through blocking cyclic AMP - protein kinase A pathway in spermatozoa.

A systems biology perspective on Nrf2-mediated antioxidant response

Acquisition of apoptotic resistance in cadmium-transformed human prostate epithelial cells: Bcl-2 overexpression blocks the activation of JNK signal transduction pathway

Activation of NRF2 ameliorates oxidative stress and cystogenesis in autosomal dominant polycystic kidney disease

Activation of Nrf2-mediated oxidative stress response in macrophages by hypochlorous acid

Acute stimulation of white adipocyte respiration by PKA-induced lipolysis

Adaptive Posttranslational Control in Cellular Stress Response Pathways and Its Relationship to Toxicity Testing and Safety Assessment

Adipose deficiency of Nrf2 in ob/ob mice results in severe metabolic syndrome

An overview of chemical inhibitors of the Nrf2-ARE signaling pathway and their potential applications in cancer therapy

Arsenic Induces p62 Expression to Form a Positive Feedback Loop with Nrf2 in Human Epidermal Keratinocytes: Implications for Preventing Arsenic-Induced Skin Cancer

Arsenic-induced malignant transformation of human keratinocytes: involvement of Nrf2

Association between arsenic suppression of adipogenesis and induction of CHOP10 via the endoplasmic reticulum stress response

CNC-bZIP protein Nrf1-dependent regulation of glucose-stimulated insulin secretion

Cadmium-induced malignant transformation in rat liver cells: role of aberrant oncogene expression and minimal role of oxidative stress.

Comparative Study on In Vitro Culture of Mouse Bone Marrow Mesenchymal Stem Cells.

Constitutive role for IRE1α-XBP1 signaling pathway in the insulin-mediated hepatic lipogenic program

Correction to "Proteomic Characterization of the Cellular Response to Nitrosative Stress Mediated by S-Nitrosoglutathione Reductase Inhibition".

Cross-regulations among NRFs and KEAP1 and effects of their silencing on arsenic-induced antioxidant response and cytotoxicity in human keratinocytes

Curcumin protects human keratinocytes against inorganic arsenite-induced acute cytotoxicity through an NRF2-dependent mechanism

Decreased enzyme activity of hepatic thioredoxin reductase and glutathione reductase in rabbits by prolonged exposure to inorganic arsenate.

Deficiency in the nuclear factor E2-related factor 2 renders pancreatic β-cells vulnerable to arsenic-induced cell damage

Deficiency in the nuclear factor E2-related factor-2 transcription factor results in impaired adipogenesis and protects against diet-induced obesity

Deficiency of long isoforms of Nfe2l1 sensitizes MIN6 pancreatic β cells to arsenite-induced cytotoxicity.

Divergent effects of sulforaphane on basal and glucose-stimulated insulin secretion in β-cells: role of reactive oxygen species and induction of endogenous antioxidants

Dose-dependent transitions in Nrf2-mediated adaptive response and related stress responses to hypochlorous acid in mouse macrophages

Drinking water disinfection byproduct iodoacetic acid induces tumorigenic transformation of NIH3T3 cells.

Effects of Nrf2 deficiency on arsenic metabolism in mice

Enhanced p62-NRF2 Feedback Loop due to Impaired Autophagic Flux Contributes to Arsenic-Induced Malignant Transformation of Human Keratinocytes

Evaluation of DNA damage in patients with arsenic poisoning: urinary 8-hydroxydeoxyguanine.

Evaluation of the association between arsenic and diabetes: a National Toxicology Program workshop review

Evidence for induction of oxidative stress caused by chronic exposure of Chinese residents to arsenic contained in drinking water

Gene deficiency of glutathione S-transferase mu isoform associated with susceptibility to lung cancer in a Chinese population

Hormesis and adaptive cellular control systems

Identification of Nrf2-dependent airway epithelial adaptive response to proinflammatory oxidant-hypochlorous acid challenge by transcription profiling

Identification of novel NRF2-regulated genes by ChIP-Seq: influence on retinoid X receptor alpha.

Induction of heme oxygenase 1 by arsenite inhibits cytokine-induced monocyte adhesion to human endothelial cells

Iodoacetic Acid Activates Nrf2-Mediated Antioxidant Response in Vitro and in Vivo

Isoniazid suppresses antioxidant response element activities and impairs adipogenesis in mouse and human preadipocytes

Keap1 silencing boosts lipopolysaccharide-induced transcription of interleukin 6 via activation of nuclear factor κB in macrophages

Long isoforms of NRF1 contribute to arsenic-induced antioxidant response in human keratinocytes

Low level, long-term inorganic arsenite exposure causes generalized resistance to apoptosis in cultured human keratinocytes: potential role in skin co-carcinogenesis.

Low-level arsenic impairs glucose-stimulated insulin secretion in pancreatic beta cells: involvement of cellular adaptive response to oxidative stress

Mathematical modeling reveals quantitative properties of KEAP1-NRF2 signaling

Mechanisms controlling the multistage post-translational processing of endogenous Nrf1α/TCF11 proteins to yield distinct isoforms within the coupled positive and negative feedback circuits

Metabolic syndrome and urinary cGMP excretion in general population

Metallothionein blocks oxidative DNA damage in vitro.

Molecular mechanism of human Nrf2 activation and degradation: role of sequential phosphorylation by protein kinase CK2.

Myeloid lineage-specific deletion of antioxidant system enhances tumor metastasis.

NRF2 Is a Potential Modulator of Hyperresistance to Arsenic Toxicity in Stem-Like Keratinocytes

Nrf1 CNC-bZIP protein promotes cell survival and nucleotide excision repair through maintaining glutathione homeostasis.

Nrf1 is time-dependently expressed and distributed in the distinct cell types after trauma to skeletal muscles in rats

Nrf2 Improves Leptin and Insulin Resistance Provoked by Hypothalamic Oxidative Stress.

Nrf2 deficiency aggravates the kidney injury induced by subacute cadmium exposure in mice

Nrf2 in alcoholic liver disease

Nrf2 in keratinocytes protects against skin fibrosis via regulating epidermal lesion and inflammatory response

Nrf2 protects pancreatic β-cells from oxidative and nitrosative stress in diabetic model mice

Nrf2-Mediated Regulation of Skeletal Muscle Glycogen Metabolism

Nuclear factor erythroid-derived factor 2-related factor 2 regulates transcription of CCAAT/enhancer-binding protein β during adipogenesis

Organic extract contaminants from drinking water activate Nrf2-mediated antioxidant response in a human cell line

Persistent oxidative stress due to absence of uncoupling protein 2 associated with impaired pancreatic beta-cell function

Phase I to II cross-induction of xenobiotic metabolizing enzymes: a feedforward control mechanism for potential hormetic responses

Prolonged exposure to insulin suppresses mitochondrial production in primary hepatocytes

Prolonged inorganic arsenite exposure suppresses insulin-stimulated AKT S473 phosphorylation and glucose uptake in 3T3-L1 adipocytes: involvement of the adaptive antioxidant response

Protective Role of Nuclear Factor E2-Related Factor 2 against Acute Oxidative Stress-Induced Pancreatic β -Cell Damage.

Proteomic characterization of the cellular response to nitrosative stress mediated by s-nitrosoglutathione reductase inhibition.

ROS signaling, oxidative stress and Nrf2 in pancreatic beta-cell function

Reactive Oxygen Species and Antioxidants in Pancreatic β-Cell Function – Yin and Yang

Reactive oxygen species and uncoupling protein 2 in pancreatic β-cell function.

Reactive oxygen species as a signal in glucose-stimulated insulin secretion

Recent advances in 2D and 3D in vitro systems using primary hepatocytes, alternative hepatocyte sources and non-parenchymal liver cells and their use in investigating mechanisms of hepatotoxicity, cell signaling and ADME.

Reduced antioxidant capacity and diet-induced atherosclerosis in uncoupling protein-2-deficient mice

Regulatory role of KEAP1 and NRF2 in PPARγ expression and chemoresistance in human non-small-cell lung carcinoma cells

Relationship between urinary cGMP excretion and serum total cholesterol levels in a general population

Serum antioxidant vitamins and risk of lung and stomach cancers in Shenyang, China ⬇️

Strain differences in arsenic-induced oxidative lesion via arsenic biomethylation between C57BL/6J and 129X1/SvJ mice

Suppression of NRF2-ARE activity sensitizes chemotherapeutic agent-induced cytotoxicity in human acute monocytic leukemia cells

The NRF2-mediated oxidative stress response pathway is associated with tumor cell resistance to arsenic trioxide across the NCI-60 panel.

The impairment of glucose-stimulated insulin secretion in pancreatic β-cells caused by prolonged glucotoxicity and lipotoxicity is associated with elevated adaptive antioxidant response.

The role of nuclear factor E2-Related factor 2 and uncoupling protein 2 in glutathione metabolism: Evidence from an in vivo gene knockout study.