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List of works by Harald Herrmann

5-azacytidine and decitabine exert proapoptotic effects on neoplastic mast cells: role of FAS-demethylation and FAS re-expression, and synergism with FAS-ligand

scientific article

A comprehensive target selectivity survey of the BCR-ABL kinase inhibitor INNO-406 by kinase profiling and chemical proteomics in chronic myeloid leukemia cells

scientific article published on 5 November 2009

A new human mast cell line expressing a functional IgE receptor converts to tumorigenic growth by KIT D816V transfection

scientific article published on 27 March 2014

Altered IgE epitope presentation: A model for hypoallergenic activity revealed for Bet v 1 trimer.

scientific article published on 18 November 2010

CD34(+)/CD38(-) stem cells in chronic myeloid leukemia express Siglec-3 (CD33) and are responsive to the CD33-targeting drug gemtuzumab/ozogamicin

scientific article published on 11 October 2011

CD52 is a molecular target in advanced systemic mastocytosis.

scientific article published on 23 April 2014

Cancer stem cell definitions and terminology: the devil is in the details

scientific article published on 11 October 2012

Cancer stem cells in basic science and in translational oncology: can we translate into clinical application?

scientific article

Combined targeting of STAT3 and STAT5: a novel approach to overcome drug resistance in chronic myeloid leukemia

scientific article published on 8 June 2017

DPPIV (CD26) as a novel stem cell marker in Ph+ chronic myeloid leukaemia

scientific article

Developmental, malignancy-related, and cross-species analysis of eosinophil, mast cell, and basophil siglec-8 expression

scientific article

Dipeptidylpeptidase IV (CD26) defines leukemic stem cells (LSC) in chronic myeloid leukemia

scientific article published on 28 April 2014

Drug-induced inhibition of phosphorylation of STAT5 overrides drug resistance in neoplastic mast cells.

scientific article published on 29 November 2017

Evaluation of cooperative antileukemic effects of nilotinib and vildagliptin in Ph+ chronic myeloid leukemia

scientific article published on 12 October 2017

Evaluation of in vitro effects of various targeted drugs on plasma cells and putative neoplastic stem cells in patients with multiple myeloma.

scientific article published on 25 August 2016

Expression of CD25 on leukemic stem cells in BCR-ABL1+ CML: Potential diagnostic value and functional implications.

scientific article published on 27 April 2017

FLAG-induced remission in a patient with acute mast cell leukemia (MCL) exhibiting t(7;10)(q22;q26) and KIT D816H

scientific article published on 26 November 2013

Glucocorticosteroids rescue basophils from dasatinib-augmented immunoglobulin E-mediated histamine release.

scientific article

High STAT5 levels mediate imatinib resistance and indicate disease progression in chronic myeloid leukemia.

scientific article

Identification of CD25 as STAT5-Dependent Growth Regulator of Leukemic Stem Cells in Ph+ CML.

scientific article published on 25 November 2015

Identification of Ponatinib as a potent inhibitor of growth, migration, and activation of neoplastic eosinophils carrying FIP1L1-PDGFRA

scientific article

Identification of basophils as a major source of hepatocyte growth factor in chronic myeloid leukemia: a novel mechanism of BCR-ABL1-independent disease progression

scientific article published on July 2012

Identification of bromodomain-containing protein-4 as a novel marker and epigenetic target in mast cell leukemia

scientific article published on 9 June 2015

Identification of campath-1 (CD52) as novel drug target in neoplastic stem cells in 5q-patients with MDS and AML.

scientific article published on 5 May 2014

Identification of heat shock protein 32 (Hsp32) as a novel target in acute lymphoblastic leukemia

scientific article published on March 2014

Identification of oncostatin M as a JAK2 V617F-dependent amplifier of cytokine production and bone marrow remodeling in myeloproliferative neoplasms

scientific article

Immunosuppression and atypical infections in CML patients treated with dasatinib at 140 mg daily

scientific article published on 9 September 2009

In vitro and in vivo growth-inhibitory effects of cladribine on neoplastic mast cells exhibiting the imatinib-resistant KIT mutation D816V.

scientific article published on 27 May 2010

Interleukin-9 (IL-9) and NPM-ALK each generate mast cell hyperplasia as single 'hit' and cooperate in producing a mastocytosis-like disease in mice

scientific article

NI-1: a novel canine mastocytoma model for studying drug resistance and IgER-dependent mast cell activation. ⬇️

scientific article published on 15 May 2012

Neoplastic stem cells: current concepts and clinical perspectives.

scientific article published on 25 February 2010

Nilotinib and imatinib are comparably effective in reducing growth of human eosinophil leukemia cells in a newly established xenograft model

scientific article

Phenotypic heterogeneity, novel diagnostic markers, and target expression profiles in normal and neoplastic human mast cells

scientific article published on 12 August 2010

Polo-like kinase-1 as a novel target in neoplastic mast cells: demonstration of growth-inhibitory effects of small interfering RNA and the Polo-like kinase-1 targeting drug BI 2536.

scientific article published on 17 January 2011

Prominin-1 (CD133, AC133) and dipeptidyl-peptidase IV (CD26) are indicators of infinitive growth in colon cancer cells

scientific article published on 15 January 2015

Quantitative assessment of the CD26+ leukemic stem cell compartment in chronic myeloid leukemia: patient-subgroups, prognostic impact, and technical aspects.

scientific article published on 29 April 2016

RNAi screen identifies Brd4 as a therapeutic target in acute myeloid leukaemia

scientific article (publication date: 3 August 2011)

Reducing allergenicity by altering allergen fold: a mosaic protein of Phl p 1 for allergy vaccination.

scientific article

Small-molecule inhibition of BRD4 as a new potent approach to eliminate leukemic stem- and progenitor cells in acute myeloid leukemia AML.

scientific article published on December 2012

Stable non-transforming minimal residual disease in Philadelphia chromosome positive acute lymphoblastic leukemia after autologous transplantation: origin from neoplastic yet ‘pre-leukemic’ stem cells? ⬇️

scientific article published on April 4, 2011

Structure and assembly properties of the intermediate filament protein vimentin: the role of its head, rod and tail domains

scientific article published on December 1996

Targeting of Hsp32 in solid tumors and leukemias: a novel approach to optimize anticancer therapy.

scientific article

Targeting of mTOR is associated with decreased growth and decreased VEGF expression in acute myeloid leukaemia cells.

scientific article published in May 2009

The Hsp32 inhibitors SMA-ZnPP and PEG-ZnPP exert major growth-inhibitory effects on D34+/CD38+ and CD34+/CD38- AML progenitor cells

scientific article published on 01 January 2012

The PI3-kinase/mTOR-targeting drug NVP-BEZ235 inhibits growth and IgE-dependent activation of human mast cells and basophils

scientific article

The effects of dasatinib on IgE receptor-dependent activation and histamine release in human basophils

scientific article published on 7 January 2008

The role of epigenetics in the regulation of apoptosis in myelodysplastic syndromes and acute myeloid leukemia.

scientific article published on 12 October 2013

Tumor stem cell research - basis and challenge for diagnosis and therapy

scientific article published on 22 July 2010

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