List of works - Juulia Jylhävä

A genome-wide association study identifies UGT1A1 as a regulator of serum cell-free DNA in young adults: The Cardiovascular Risk in Young Finns Study

scientific article

Ageing-associated changes in the human DNA methylome: genomic locations and effects on gene expression.

scientific article published on 14 March 2015

Aging is associated with quantitative and qualitative changes in circulating cell-free DNA: The Vitality 90+ study ⬇️

scientific article published on November 13, 2010

Aging-associated DNA methylation changes in middle-aged individuals: the Young Finns study

scientific article published on 9 February 2016

Aging-associated increase in indoleamine 2,3-dioxygenase (IDO) activity appears to be unrelated to the transcription of the IDO1 or IDO2 genes in peripheral blood mononuclear cells

scientific article

Biological Age Predictors.

scientific article

Body Mass Index and Waist Circumference as Predictors of Disability in Nonagenarians: The Vitality 90+ Study

scientific article

Can markers of biological age predict dependency in old age?

scientific article published on 21 January 2019

Cardiometabolic and Inflammatory Biomarkers as Mediators Between Educational Attainment and Functioning at the Age of 90 Years

scientific article published on 31 August 2015

Characterization of the role of distinct plasma cell‐free DNA species in age‐associated inflammation and frailty ⬇️

scientific article published on April 1, 2013

Circulating cell-free DNA in health and disease — the relationship to health behaviours, ageing phenotypes and metabolomics

scientific article published in 2022

Circulating cell-free DNA is associated with cardiometabolic risk factors: The Health 2000 Survey

article

Circulating cell-free DNA is associated with mortality and inflammatory markers in nonagenarians: the Vitality 90+ Study

scientific article published on 03 March 2012

Circulating miR-21, miR-146a and Fas ligand respond to postmenopausal estrogen-based hormone replacement therapy--a study with monozygotic twin pairs

scientific article

Complement factor H 402His variant confers an increased mortality risk in Finnish nonagenarians: the Vitality 90+ study

scientific article published on 26 October 2008

Cytomegalovirus (CMV)-dependent and -independent changes in the aging of the human immune system: a transcriptomic analysis

scientific article published on 2 January 2013

Cytomegalovirus infection accelerates epigenetic aging.

scientific article published on 17 October 2015

DNA Methylation and All-Cause Mortality in Middle-Aged and Elderly Danish Twins

scientific article published on 8 February 2018

Determinants of longevity: genetics, biomarkers and therapeutic approaches.

scientific article published on January 2014

Dynamics and interactions of parvoviral NS1 protein in the nucleus

scientific article published on 5 April 2007

Early life factors as predictors of age-associated deficit accumulation across 17 years from midlife into old age

scientific article

Epigenome-wide association study of level and change in cognitive abilities from midlife through late life

scientific article published on 21 April 2021

Expression profiling of immune-associated genes in peripheral blood mononuclear cells reveals baseline differences in co-stimulatory signalling between nonagenarians and younger controls: the vitality 90+ study

scientific article published in December 2010

FGF21 is a biomarker for mitochondrial translation and mtDNA maintenance disorders

scientific article published on 28 October 2016

Fatal outcome in bacteremia is characterized by high plasma cell free DNA concentration and apoptotic DNA fragmentation: a prospective cohort study

scientific article

Frailty index as a predictor of all-cause and cause-specific mortality in a Swedish population-based cohort.

scientific article published on 19 December 2017

Frailty trajectories in three longitudinal studies of aging: Is the level or the rate of change more predictive of mortality?

scientific article published on 01 November 2021

Gene variants as determinants of longevity: focus on the inflammatory factors.

scientific article published on 11 September 2009

Genetics of C-reactive protein and complement factor H have an epistatic effect on carotid artery compliance: the Cardiovascular Risk in Young Finns Study

article

Genome-wide association study does not reveal major genetic determinants for anti-cytomegalovirus antibody response

article

Heart rate variability is independently associated with C-reactive protein but not with Serum amyloid A. The Cardiovascular Risk in Young Finns Study

scholarly article by Atte Haarala et al published 17 February 2011 in European Journal of Clinical Investigation

High cell-free DNA predicts fatal outcome among Staphylococcus aureus bacteraemia patients with intensive care unit treatment

scientific article

High plasma level of long pentraxin 3 (PTX3) is associated with fatal disease in bacteremic patients: a prospective cohort study

scientific article

Human endogenous retrovirus HERV-K(HML-2) env expression is not associated with markers of immunosenescence.

scientific article published on 31 July 2017

IL-7 concentration is increased in nonagenarians but is not associated with markers of T cell immunosenescence.

scientific article published on 22 September 2011

Identification of a prognostic signature for old-age mortality by integrating genome-wide transcriptomic data with the conventional predictors: the Vitality 90+ Study.

scientific article

Increased Paternal Age at Conception Is Associated with Transcriptomic Changes Involved in Mitochondrial Function in Elderly Individuals

scientific article

Indoleamine 2,3-dioxygenase activity and expression in patients with chronic lymphocytic leukemia

scientific article published on 13 September 2012

Internalization of novel non-viral vector TAT-streptavidin into human cells

scientific article

Length of paternal lifespan is manifested in the DNA methylome of their nonagenarian progeny.

scientific article published on 30 September 2015

Lung-protective ventilation suppresses plasma levels of cell-free DNA in porcine experimental postoperative sepsis

Methylomic predictors demonstrate the role of NF-κB in old-age mortality and are unrelated to the aging-associated epigenetic drift.

scientific article published on 22 March 2016

Molecular mechanisms associated with the strength of the anti-CMV response in nonagenarians.

scientific article published on 31 January 2014

Number of sons contributes to ageing-associated inflammation

scientific article

Obesity accelerates epigenetic aging in middle-aged but not in elderly individuals

scientific article published on 14 February 2017

Parvovirus induced alterations in nuclear architecture and dynamics

scientific article

Pentraxin 3 (PTX3) is associated with cardiovascular risk factors: the Health 2000 Survey

article

Plasma cell-free DNA and qSOFA score predict 7-day mortality in 481 emergency department bacteraemia patients.

scientific article

Plasma cell-free DNA levels are elevated in acute Puumala hantavirus infection

scientific article

Plasma pentraxin-3 and coagulation and fibrinolysis variables during acute Puumala hantavirus infection and associated thrombocytopenia

scientific article

Relation of high cytomegalovirus antibody titres to blood pressure and brachial artery flow-mediated dilation in young men: the Cardiovascular Risk in Young Finns Study

article

Self-rated health in individuals with and without disease is associated with multiple biomarkers representing multiple biological domains

scientific article published on 17 March 2021

Serum amyloid A and C-reactive protein concentrations are differently associated with markers of autoimmunity in patients with primary Sjögren's syndrome

scientific article published on 15 October 2009

Serum amyloid A is independently associated with metabolic risk factors but not with early atherosclerosis: the Cardiovascular Risk in Young Finns Study

scientific article published in September 2009

The concentration of cell-free DNA in focal epilepsy.

scientific article published on 11 April 2013

The concentration of cell-free DNA in video-EEG patients is dependent on the epilepsy syndrome and duration of epilepsy

scientific article published on 01 January 2016

The frailty index is a predictor of cause-specific mortality independent of familial effects from midlife onwards: a large cohort study

scientific article published on 15 May 2019

The pathogenesis of nephropathia epidemica: new knowledge and unanswered questions

scientific article published on 12 October 2013

The trajectory of the blood DNA methylome ageing rate is largely set before adulthood: evidence from two longitudinal studies

scientific article published on 14 June 2016

Transcriptional analysis reveals gender-specific changes in the aging of the human immune system.

scientific article published on 11 June 2013

Transcriptomic and epigenetic analyses reveal a gender difference in aging-associated inflammation: the Vitality 90+ study.

scientific article published on 19 July 2015

List of works by Juulia Jylhävä

A genome-wide association study identifies UGT1A1 as a regulator of serum cell-free DNA in young adults: The Cardiovascular Risk in Young Finns Study

Ageing-associated changes in the human DNA methylome: genomic locations and effects on gene expression.

Aging is associated with quantitative and qualitative changes in circulating cell-free DNA: The Vitality 90+ study ⬇️

Aging-associated DNA methylation changes in middle-aged individuals: the Young Finns study

Aging-associated increase in indoleamine 2,3-dioxygenase (IDO) activity appears to be unrelated to the transcription of the IDO1 or IDO2 genes in peripheral blood mononuclear cells

Biological Age Predictors.

Body Mass Index and Waist Circumference as Predictors of Disability in Nonagenarians: The Vitality 90+ Study

Can markers of biological age predict dependency in old age?

Cardiometabolic and Inflammatory Biomarkers as Mediators Between Educational Attainment and Functioning at the Age of 90 Years

Characterization of the role of distinct plasma cell‐free DNA species in age‐associated inflammation and frailty ⬇️

Circulating cell-free DNA in health and disease — the relationship to health behaviours, ageing phenotypes and metabolomics

Circulating cell-free DNA is associated with cardiometabolic risk factors: The Health 2000 Survey

Circulating cell-free DNA is associated with mortality and inflammatory markers in nonagenarians: the Vitality 90+ Study

Circulating miR-21, miR-146a and Fas ligand respond to postmenopausal estrogen-based hormone replacement therapy--a study with monozygotic twin pairs

Complement factor H 402His variant confers an increased mortality risk in Finnish nonagenarians: the Vitality 90+ study

Cytomegalovirus (CMV)-dependent and -independent changes in the aging of the human immune system: a transcriptomic analysis

Cytomegalovirus infection accelerates epigenetic aging.

DNA Methylation and All-Cause Mortality in Middle-Aged and Elderly Danish Twins

Determinants of longevity: genetics, biomarkers and therapeutic approaches.

Dynamics and interactions of parvoviral NS1 protein in the nucleus

Early life factors as predictors of age-associated deficit accumulation across 17 years from midlife into old age

Epigenome-wide association study of level and change in cognitive abilities from midlife through late life

Expression profiling of immune-associated genes in peripheral blood mononuclear cells reveals baseline differences in co-stimulatory signalling between nonagenarians and younger controls: the vitality 90+ study

FGF21 is a biomarker for mitochondrial translation and mtDNA maintenance disorders

Fatal outcome in bacteremia is characterized by high plasma cell free DNA concentration and apoptotic DNA fragmentation: a prospective cohort study

Frailty index as a predictor of all-cause and cause-specific mortality in a Swedish population-based cohort.

Frailty trajectories in three longitudinal studies of aging: Is the level or the rate of change more predictive of mortality?

Gene variants as determinants of longevity: focus on the inflammatory factors.

Genetics of C-reactive protein and complement factor H have an epistatic effect on carotid artery compliance: the Cardiovascular Risk in Young Finns Study

Genome-wide association study does not reveal major genetic determinants for anti-cytomegalovirus antibody response

Heart rate variability is independently associated with C-reactive protein but not with Serum amyloid A. The Cardiovascular Risk in Young Finns Study

High cell-free DNA predicts fatal outcome among Staphylococcus aureus bacteraemia patients with intensive care unit treatment

High plasma level of long pentraxin 3 (PTX3) is associated with fatal disease in bacteremic patients: a prospective cohort study

Human endogenous retrovirus HERV-K(HML-2) env expression is not associated with markers of immunosenescence.

IL-7 concentration is increased in nonagenarians but is not associated with markers of T cell immunosenescence.

Identification of a prognostic signature for old-age mortality by integrating genome-wide transcriptomic data with the conventional predictors: the Vitality 90+ Study.

Increased Paternal Age at Conception Is Associated with Transcriptomic Changes Involved in Mitochondrial Function in Elderly Individuals

Indoleamine 2,3-dioxygenase activity and expression in patients with chronic lymphocytic leukemia

Internalization of novel non-viral vector TAT-streptavidin into human cells

Length of paternal lifespan is manifested in the DNA methylome of their nonagenarian progeny.

Lung-protective ventilation suppresses plasma levels of cell-free DNA in porcine experimental postoperative sepsis

Methylomic predictors demonstrate the role of NF-κB in old-age mortality and are unrelated to the aging-associated epigenetic drift.

Molecular mechanisms associated with the strength of the anti-CMV response in nonagenarians.

Number of sons contributes to ageing-associated inflammation

Obesity accelerates epigenetic aging in middle-aged but not in elderly individuals

Parvovirus induced alterations in nuclear architecture and dynamics

Pentraxin 3 (PTX3) is associated with cardiovascular risk factors: the Health 2000 Survey

Plasma cell-free DNA and qSOFA score predict 7-day mortality in 481 emergency department bacteraemia patients.

Plasma cell-free DNA levels are elevated in acute Puumala hantavirus infection

Plasma pentraxin-3 and coagulation and fibrinolysis variables during acute Puumala hantavirus infection and associated thrombocytopenia

Relation of high cytomegalovirus antibody titres to blood pressure and brachial artery flow-mediated dilation in young men: the Cardiovascular Risk in Young Finns Study

Self-rated health in individuals with and without disease is associated with multiple biomarkers representing multiple biological domains

Serum amyloid A and C-reactive protein concentrations are differently associated with markers of autoimmunity in patients with primary Sjögren's syndrome

Serum amyloid A is independently associated with metabolic risk factors but not with early atherosclerosis: the Cardiovascular Risk in Young Finns Study

The concentration of cell-free DNA in focal epilepsy.

The concentration of cell-free DNA in video-EEG patients is dependent on the epilepsy syndrome and duration of epilepsy

The frailty index is a predictor of cause-specific mortality independent of familial effects from midlife onwards: a large cohort study

The pathogenesis of nephropathia epidemica: new knowledge and unanswered questions

The trajectory of the blood DNA methylome ageing rate is largely set before adulthood: evidence from two longitudinal studies

Transcriptional analysis reveals gender-specific changes in the aging of the human immune system.

Transcriptomic and epigenetic analyses reveal a gender difference in aging-associated inflammation: the Vitality 90+ study.