List of works by Sean Humphrey

A Positive Feedback Loop between Akt and mTORC2 via SIN1 Phosphorylation

scientific article published on 29 July 2015

ABHD15 regulates adipose tissue lipolysis and hepatic lipid accumulation

scientific article published on 06 May 2019

Dynamic Metabolomics Reveals that Insulin Primes the Adipocyte for Glucose Metabolism

scientific article published in December 2017

Dynamic adipocyte phosphoproteome reveals that Akt directly regulates mTORC2.

scientific article published on 16 May 2013

Global Phosphoproteomic Analysis of Human Skeletal Muscle Reveals a Network of Exercise-Regulated Kinases and AMPK Substrates.

scientific article

Global redox proteome and phosphoproteome analysis reveals redox switch in Akt

scientific article published on 02 December 2019

Glucose-regulated and drug-perturbed phosphoproteome reveals molecular mechanisms controlling insulin secretion

scientific article published on 14 November 2016

High-throughput and high-sensitivity phosphoproteomics with the EasyPhos platform

scientific article published on 01 September 2018

High-throughput phosphoproteomics reveals in vivo insulin signaling dynamics.

scientific article published on 17 August 2015

Hyperactivation of the Insulin Signaling Pathway Improves Intracellular Proteostasis by Coordinately Up-regulating the Proteostatic Machinery in Adipocytes

scientific article published on 13 October 2016

Illuminating the dark phosphoproteome

scientific article published on 22 January 2019

In vivo brain GPCR signaling elucidated by phosphoproteomics.

scientific article published in June 2018

KinasePA: Phosphoproteomics data annotation using hypothesis driven kinase perturbation analysis.

scientific article

Mechanism of Regulation of Intrachromatid Recombination and Long-Range Chromosome Interactions in Saccharomyces cerevisiae

scientific article

Mitochondrial CoQ deficiency is a common driver of mitochondrial oxidants and insulin resistance.

scientific article

Multi-omic Profiling Reveals Dynamics of the Phased Progression of Pluripotency

scientific article published on 08 May 2019

NanoBlow: A Simple Device To Limit Contaminants during NanoLC-MS

scientific article published on 03 July 2019

PhosphOrtholog: a web-based tool for cross-species mapping of orthologous protein post-translational modifications

scientific article published on 19 August 2015

Phosphoproteomics Reveals the GSK3-PDX1 Axis as a Key Pathogenic Signaling Node in Diabetic Islets

scientific article published on 14 March 2019

Phosphoproteomics of Acute Cell Stressors Targeting Exercise Signaling Networks Reveal Drug Interactions Regulating Protein Secretion

scientific article published on 01 November 2019

Phosphorylation Is a Central Mechanism for Circadian Control of Metabolism and Physiology

scientific article published on 29 October 2016

Positive-unlabeled ensemble learning for kinase substrate prediction from dynamic phosphoproteomics data.

scientific article

Protein Phosphorylation: A Major Switch Mechanism for Metabolic Regulation.

scientific article

Proteomic Analysis of Human Plasma during Intermittent Fasting

scientific article published on 01 April 2019

QCMAP: An Interactive Web-Tool for Performance Diagnosis and Prediction of LC-MS Systems

scientific article published on 13 June 2019

Quantitative proteomic analysis of the adipocyte plasma membrane.

scientific article published on 18 October 2011

RagC phosphorylation autoregulates mTOR complex 1

scientific article published on 14 December 2018

Sphingosine 1-phosphate but not Fingolimod protects neurons against excitotoxic cell death by inducing neurotrophic gene expression in astrocytes

scientific article published on 19 November 2019

TBC1D13 is a RAB35 specific GAP that plays an important role in GLUT4 trafficking in adipocytes

scientific journal article

Targeted phosphoproteomics of insulin signaling using data-independent acquisition mass spectrometry.

scientific article

The amino acid transporter, SLC1A3, is plasma membrane-localised in adipocytes and its activity is insensitive to insulin

scientific article published on 29 December 2016

Transcriptional network dynamics during the progression of pluripotency revealed by integrative statistical learning

scientific article published on 01 February 2020

Uncaging akt

scientific article published on 08 May 2012

Unraveling Kinase Activation Dynamics Using Kinase-Substrate Relationships from Temporal Large-Scale Phosphoproteomics Studies

scientific article

mTORC1 Is a Major Regulatory Node in the FGF21 Signaling Network in Adipocytes.

scientific article published in September 2016

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