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List of works by Pierachille Santus

A pilot study to assess the effects of combining fluticasone propionate/salmeterol and tiotropium on the airflow obstruction of patients with severe-to-very severe COPD.

scientific article published on 7 July 2006

A single high dose of formoterol is as effective as the same dose administered in a cumulative manner in patients with acute exacerbation of COPD ⬇️

scientific article published on May 1, 2003

A systematic review on tracheostomy decannulation: a proposal of a quantitative semiquantitative clinical score.

scientific article

Airway occlusion assessed by single breath N2 test and lung P-V curve in healthy subjects and COPD patients

scientific article published on 6 September 2016

Antileukotrienes in clinical development for asthma

scientific article

Anxiety and depression in COPD patients: The roles of gender and disease severity

scientific article published on 13 March 2006

Anxiety and depression in asthma

scientific article published on January 2011

Assessing and accessing the small airways; implications for asthma management

scientific article published on 13 October 2012

Assessment of acute bronchodilator effects from specific airway resistance changes in stable COPD patients

scientific article published on 12 April 2014

Asthma management in a specialist setting: Results of an Italian Respiratory Society survey.

scientific article published on 21 March 2017

Avoiding misdiagnosis in patients with dyspnea and wheezing: a case report illustrating the clinical implications of fixation error

scientific article published on 08 February 2017

Azithromycin and lower respiratory tract infections.

scientific article

Bronchodilating effect of oxitropium bromide in heart disease patients with exacerbations of COPD: double-blind, randomized, controlled study.

scientific article published in March 2002

Bronchodilator effect of an inhaled combination therapy with salmeterol + fluticasone and formoterol + budesonide in patients with COPD.

scientific article published in May 2003

Bronchodilators modulate inflammation in chronic obstructive pulmonary disease subjects

scientific article published on 31 May 2012

Budesonide/formoterol dry powder in asthma: an option for control as maintenance and reliever therapy

scientific article published on February 2010

Cardiopulmonary exercise testing and second-line pulmonary function tests to detect obstructive pattern in symptomatic smokers with borderline spirometry.

scientific article published on 10 April 2017

Characteristics of newly diagnosed COPD patients treated with triple inhaled therapy by general practitioners: a real world Italian study.

scientific article published on 7 September 2017

Close correlation between anxiety, depression, and asthma control.

scientific article published on 4 September 2009

Comparison of the bronchodilating effect of salmeterol and zafirlukast in combination with that of their use as single treatments in asthma and chronic obstructive pulmonary disease.

scientific article published in January 2001

Differences in the efficacy and safety among inhaled corticosteroids (ICS)/long-acting beta2-agonists (LABA) combinations in the treatment of chronic obstructive pulmonary disease (COPD): Role of ICS.

scientific article

Disability in moderate chronic obstructive pulmonary disease: prevalence, burden and assessment - results from a real-life study.

scientific article published on 21 January 2015

Doctor–patient relationship: A resource to improve respiratory diseases management

scientific article published on 01 May 2012

Does Improving Exercise Capacity and Daily Activity Represent the Holistic Perspective of a New COPD Approach?

scientific article published on 04 August 2015

Doppler echocardiographic assessment of the effects of inhaled long-acting beta2-agonists on pulmonary artery pressure in COPD patients

scientific article published on 06 March 2006

Effect of formoterol, tiotropium, and their combination in patients with acute exacerbation of chronic obstructive pulmonary disease: a pilot study

scientific article published on 19 April 2006

Effect of indacaterol on lung deflation improves cardiac performance in hyperinflated COPD patients: an interventional, randomized, double-blind clinical trial

scientific article

Effect of inhaled bronchodilators on inspiratory capacity and dyspnoea at rest in COPD.

scientific article

Effects of aclidinium on determinants of COPD severity: symptoms and quality of life

scientific article

Epidemiology of clinical trials of medicines in respiratory diseases in Europe and Italy

scientific article published on 20 February 2017

Expiratory flow-limitation and heliox breathing in resting and exercising COPD patients

scientific article published on 19 September 2009

Faster reduction in hyperinflation and improvement in lung ventilation inhomogeneity promoted by aclidinium compared to glycopyrronium in severe stable COPD patients. A randomized crossover study.

scientific article published on 5 November 2015

Formoterol fumarate + glycopyrrolate for the treatment of chronic obstructive pulmonary disease.

scientific article published on 23 August 2016

Genuair® Usability Test: Results of a National Public Survey of the Elderly

scientific article published on 8 December 2015

Highlights on the appropriate use of fluoroquinolones in respiratory tract infections

scientific article

How air pollution influences clinical management of respiratory diseases. A case-crossover study in Milan

scientific article

Improvements in Lung Diffusion Capacity following Pulmonary Rehabilitation in COPD with and without Ventilation Inhomogeneity.

scientific article published on 7 September 2016

Is the six-minute walk test useful or useless in systemic sclerosis?

scientific article published on 22 May 2017

Onset of action of formoterol/budesonide in single inhaler vs. formoterol in patients with COPD.

scientific article

Onset of action of single doses of formoterol administered via Turbuhaler in patients with stable COPD.

scientific article

Oxidative stress and respiratory system: pharmacological and clinical reappraisal of N-acetylcysteine

scientific article

PD-1 blockade counteracts post–COVID-19 immune abnormalities and stimulates the anti–SARS-CoV-2 immune response

scientific article published in 2021

Physical activity impairment in depressed COPD subjects

scientific article

Prostaglandin D2 receptor antagonists in early development as potential therapeutic options for asthma

scientific article

Prulifloxacin: a brief review of its potential in the treatment of acute exacerbation of chronic bronchitis

scientific article

Pulmonary Rehabilitation in COPD: A Reappraisal (2008-2012)

scientific article published on 9 January 2013

Randomized Controlled Trials and real life studies. Approaches and methodologies: a clinical point of view.

scientific article published on 24 January 2014

Rapid on-site evaluation improves needle aspiration sensitivity in the diagnosis of central lung cancers: a randomized trial

scientific article published on 10 April 2013

Safety and pharmacological profile of tiotropium bromide.

scientific article published on May 2009

Salmeterol improves fluid clearance from alveolar-capillary membrane in COPD patients: A pilot study

scientific article published on 06 January 2012

Salmeterol/fluticasone propionate in a Single Inhaler Device versus theophylline+fluticasone propionate in patients with COPD.

scientific article

Severity of respiratory failure at admission and in-hospital mortality in patients with COVID-19: a prospective observational multicentre study

scientific article published on 10 October 2020

Small airway disease in asthma: pathophysiological and diagnostic considerations

scientific article

State of the Heart in Chronic Obstructive Pulmonary Disease: The Best Is Yet to Come

scientific article published on 01 December 2016

Symptom variability and control in COPD: Advantages of dual bronchodilation therapy

scientific article published on 2 March 2017

The Airways' Mechanical Stress in Lung Disease: Implications for COPD Pathophysiology and Treatment Evaluation

scientific article published on 05 September 2019

The evidence on tiotropium bromide in asthma: from the rationale to the bedside

scientific article

The old open question of marijuana and healthcare: Flares from NANHES

scientific article published on 22 August 2016

The pharmacodynamic effects of single inhaled doses of formoterol, tiotropium and their combination in patients with COPD.

scientific article

Tiotropium is less likely to induce oxygen desaturation in stable COPD patients compared to long-acting beta2-agonists

scientific article published on 30 March 2007

Tiotropium: what came after the UPLIFT study

scientific article published on 28 January 2012

Understanding the burden of pneumococcal disease in adults

scientific article

Which factors affect the choice of the inhaler in chronic obstructive respiratory diseases?

scientific article published on 24 February 2015

Why use long acting bronchodilators in chronic obstructive lung diseases? An extensive review on formoterol and salmeterol

scientific article published on 03 June 2015

Withdrawal of inhaled corticosteroids in COPD: A meta-analysis

scientific article published on 9 June 2017

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